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(NPR)   A new Alzheimer's drug didn't cause bleeding brains in 4/5 patients   (npr.org) divider line
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    More: Interesting, Alzheimer's disease, Clinical trial, experimental drug, Dr. Madhav Thambisetty of the National Institute, infusions of lecanemab, Dr. Christopher van Dyck, Cognition, rate of cognitive decline  
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406 clicks; posted to STEM » on 30 Nov 2022 at 3:30 PM (16 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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Arkanaut
2022-11-30 4:08:20 PM  
1 vote:
People who got infusions of lecanemab scored about half a point better on a zero-to-18-point scale of mental functioning, a slight but statistically significant difference.

Question is, how far behind normal people are Alzheimer patients (or at least, Alzheimer patients at this stage of the disease) on this scale? If it's 1 or 2 points, then maybe that's a pretty big deal; if it's 10 points, it seems like it's not worth the risk.
 
LockeOak
2022-11-30 4:24:26 PM  
1 vote:

Arkanaut: People who got infusions of lecanemab scored about half a point better on a zero-to-18-point scale of mental functioning, a slight but statistically significant difference.

Question is, how far behind normal people are Alzheimer patients (or at least, Alzheimer patients at this stage of the disease) on this scale? If it's 1 or 2 points, then maybe that's a pretty big deal; if it's 10 points, it seems like it's not worth the risk.


I think the NYTimes article said it slowed the progression by 27%.
 
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