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(Ars Technica)   Scientists have concluded that they don't know why transplanting a pig's heart into a human didn't work   (arstechnica.com) divider line
    More: Unlikely, Heart, Immune system, Blood, Circulatory system, weight loss, publication of a research paper, heart disease, human patient  
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653 clicks; posted to STEM » on 25 Jun 2022 at 2:25 AM (7 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



35 Comments     (+0 »)
View Voting Results: Smartest and Funniest
 
2022-06-24 8:10:34 PM  
It kept the guy alive longer than he would have been without it.
 
2022-06-24 8:29:42 PM  
But the patient had what the researchers refer to as "poor adherence to treatment,"

I wonder if that has anything to do with it.
 
2022-06-24 8:39:38 PM  
Glad that they included a picture of what typical muscle cells look like.

/Geez arstechnica. Did CNN buy you?
 
2022-06-24 8:46:28 PM  
Well, now that we can't abort the spare ones, we sure shouldn't be extending the existing ones
 
2022-06-24 8:57:59 PM  
pig != long pig?
 
2022-06-24 9:54:14 PM  
Because even your own body will eat itself if it doesn't weed out over-aggressive immune cells. There's an entire organ dedicated to doing that, and its devolution with age is a large part of why you get arthritis.  Throw in actual species-foreign proteins and it's even more of a crapshoot.
 
2022-06-24 10:22:55 PM  
Well is was a genetically engineered pig. Maybe not enough 5G?
 
2022-06-24 10:27:28 PM  
Sad that this attempt didn't work. The shortages of transplantable organs remains a severe setback to keeping some patients alive.
 
2022-06-25 12:34:01 AM  

IgG4: Well is was a genetically engineered pig. Maybe not enough 5G?


A weird side story to this is that they had to get rid of the gene for Alpha Galactose in these pigs to make them immunologically acceptable transplant donors for humans. Alpha Gal is what people how have been bitten by the lone star tick become allergic to and prevents them from eating red meat. So after they harvest the usable organs you still have a whole pig carcass on your hands. So when the company sponsoring this trial was at it the also go licensed as a food production facility to make bacon and pork chops for Alpha Gal sensitive folks.
 
2022-06-25 3:10:27 AM  

IgG4: IgG4: Well is was a genetically engineered pig. Maybe not enough 5G?

A weird side story to this is that they had to get rid of the gene for Alpha Galactose in these pigs to make them immunologically acceptable transplant donors for humans. Alpha Gal is what people how have been bitten by the lone star tick become allergic to and prevents them from eating red meat. So after they harvest the usable organs you still have a whole pig carcass on your hands. So when the company sponsoring this trial was at it the also go licensed as a food production facility to make bacon and pork chops for Alpha Gal sensitive folks.


No no no. None of that is true.
 
2022-06-25 3:18:40 AM  

Spectrum: IgG4: IgG4: Well is was a genetically engineered pig. Maybe not enough 5G?

A weird side story to this is that they had to get rid of the gene for Alpha Galactose in these pigs to make them immunologically acceptable transplant donors for humans. Alpha Gal is what people how have been bitten by the lone star tick become allergic to and prevents them from eating red meat. So after they harvest the usable organs you still have a whole pig carcass on your hands. So when the company sponsoring this trial was at it the also go licensed as a food production facility to make bacon and pork chops for Alpha Gal sensitive folks.

No no no. None of that is true.


I Googled and all I got was this article about Smithfield Foods selling heparin and selling pig guts for transplants.

Smithfield Foods and Pig-to-Human Organ Transplants - The Atlantic
 
2022-06-25 4:51:16 AM  
That article was genuinely fascinating, and would be exciting research to be a part of.
 
2022-06-25 4:56:00 AM  
Did they try it with a police officer or republicans?
 
2022-06-25 7:38:44 AM  
Was the recipient a republican?

Because as that song by Loverboy says, pig and elephant DNA just won't splice.
 
2022-06-25 8:30:43 AM  

Bootleg: But the patient had what the researchers refer to as "poor adherence to treatment,"

I wonder if that has anything to do with it.


Problem is that nobody who isn't already in a pretty bad & desperate way is going to be medically or ethically a candidate for this sort of an experiment.

And that's what it certainly was, btw. An experiment everyone including the recipient knew would most likely end in his death but hopefully provide some advancement toward helping others.
 
2022-06-25 9:19:06 AM  

Spectrum: IgG4: IgG4: Well is was a genetically engineered pig. Maybe not enough 5G?

A weird side story to this is that they had to get rid of the gene for Alpha Galactose in these pigs to make them immunologically acceptable transplant donors for humans. Alpha Gal is what people how have been bitten by the lone star tick become allergic to and prevents them from eating red meat. So after they harvest the usable organs you still have a whole pig carcass on your hands. So when the company sponsoring this trial was at it the also go licensed as a food production facility to make bacon and pork chops for Alpha Gal sensitive folks.

No no no. None of that is true.


https://www.fda.gov/news-events/press-announcements/fda-approves-first-its-kind-intentional-genomic-alteration-line-domestic-pigs-both-human-food
 
2022-06-25 10:32:37 AM  

AirForceVet: Sad that this attempt didn't work. The shortages of transplantable organs remains a severe setback to keeping some patients alive.


All it would take to fix this is to make organ donation opt-out instead of opt-in, but no...., we're too chickenshiat to actually do that.
 
2022-06-25 11:01:31 AM  

Izunbacol: Spectrum: IgG4: IgG4: Well is was a genetically engineered pig. Maybe not enough 5G?

A weird side story to this is that they had to get rid of the gene for Alpha Galactose in these pigs to make them immunologically acceptable transplant donors for humans. Alpha Gal is what people how have been bitten by the lone star tick become allergic to and prevents them from eating red meat. So after they harvest the usable organs you still have a whole pig carcass on your hands. So when the company sponsoring this trial was at it the also go licensed as a food production facility to make bacon and pork chops for Alpha Gal sensitive folks.

No no no. None of that is true.

https://www.fda.gov/news-events/press-announcements/fda-approves-first-its-kind-intentional-genomic-alteration-line-domestic-pigs-both-human-food


Huh. I stand corrected.
 
2022-06-25 12:22:02 PM  

Spectrum: Izunbacol: Spectrum: IgG4: IgG4: Well is was a genetically engineered pig. Maybe not enough 5G?

A weird side story to this is that they had to get rid of the gene for Alpha Galactose in these pigs to make them immunologically acceptable transplant donors for humans. Alpha Gal is what people how have been bitten by the lone star tick become allergic to and prevents them from eating red meat. So after they harvest the usable organs you still have a whole pig carcass on your hands. So when the company sponsoring this trial was at it the also go licensed as a food production facility to make bacon and pork chops for Alpha Gal sensitive folks.

No no no. None of that is true.

https://www.fda.gov/news-events/press-announcements/fda-approves-first-its-kind-intentional-genomic-alteration-line-domestic-pigs-both-human-food

Huh. I stand corrected.


Fark user imageView Full Size
 
2022-06-25 12:59:43 PM  

aleister_greynight: It kept the guy alive longer than he would have been without it.


Especially after removing the original!
 
2022-06-25 2:15:37 PM  

aleister_greynight: It kept the guy alive longer than he would have been without it.


That and surgery pays very well.
 
2022-06-25 2:16:18 PM  

Bootleg: But the patient had what the researchers refer to as "poor adherence to treatment,"

I wonder if that has anything to do with it.


Blame the patient

Sounds abt typical
 
2022-06-25 2:17:39 PM  

koder: Because even your own body will eat itself if it doesn't weed out over-aggressive immune cells. There's an entire organ dedicated to doing that, and its devolution with age is a large part of why you get arthritis.  Throw in actual species-foreign proteins and it's even more of a crapshoot.


Life sucks


In a nutshell

If you live long enough everyone gets cancer
 
2022-06-25 2:20:08 PM  

Bootleg: But the patient had what the researchers refer to as "poor adherence to treatment,"

I wonder if that has anything to do with it.


"He decided to become one with the pig, and only ate bacon"
 
2022-06-25 2:21:55 PM  

trialpha: AirForceVet: Sad that this attempt didn't work. The shortages of transplantable organs remains a severe setback to keeping some patients alive.

All it would take to fix this is to make organ donation opt-out instead of opt-in, but no...., we're too chickenshiat to actually do that.


Sell your eyeball man

Who said they arent taking shiat from inside you anyway??
 
2022-06-25 2:28:59 PM  
They did WHAT?

That's not kosher.
 
2022-06-25 5:09:37 PM  

koder: Because even your own body will eat itself if it doesn't weed out over-aggressive immune cells. There's an entire organ dedicated to doing that, and its devolution with age is a large part of why you get arthritis.  Throw in actual species-foreign proteins and it's even more of a crapshoot.


But they altered the DNA so it wouldn't be rejected.. and the organ itself wasn't.

I think the guy was just gonna die. They do this in people who have one foot in the grave anyway.
 
2022-06-25 5:30:34 PM  
Have they ever managed, even in vitro, to get cells from two species to form a single tissue? Seems like that would be necessary for a pig's heart to survive in a human body. Eventually the pig's heart would form a scaffold for human heart tissue, or it would just rot away.
 
2022-06-25 9:36:15 PM  
Try putting a few into strong healthy people. Just a thought.
 
2022-06-25 10:14:48 PM  

drewogatory: Try putting a few into strong healthy people. Just a thought.


Hands up any volunteers.

*crickets*

Although if they can nail the "one foot in the grave" market, it'll take longer to come to market, but the product will be bulletproof when expanded out. They'll see and resolve every unforeseeable issue before it's market ready.
 
2022-06-25 11:49:31 PM  

Linux_Yes: trialpha: AirForceVet: Sad that this attempt didn't work. The shortages of transplantable organs remains a severe setback to keeping some patients alive.

All it would take to fix this is to make organ donation opt-out instead of opt-in, but no...., we're too chickenshiat to actually do that.

Sell your eyeball man

Who said they arent taking shiat from inside you anyway??


That's what I do!  Those f@kers that come in here spouting 'my rights' are the first to go.  I don't care about your rights.  You came to my volcano lair to participate in the game show.  Don't go whining about it when I cut your legs off and throw you in the lava.  You were my brother.  You were the chosen one.  Now someone else can use those legs.

Why didn't Obi-wan think of all the people who might need a leg transplant, and use the force to save those legs?  Thoughtless.  No wonder Anakin turned.
 
2022-06-25 11:52:21 PM  

aungen: Linux_Yes: trialpha: AirForceVet: Sad that this attempt didn't work. The shortages of transplantable organs remains a severe setback to keeping some patients alive.

All it would take to fix this is to make organ donation opt-out instead of opt-in, but no...., we're too chickenshiat to actually do that.

Sell your eyeball man

Who said they arent taking shiat from inside you anyway??

That's what I do!  Those f@kers that come in here spouting 'my rights' are the first to go.  I don't care about your rights.  You came to my volcano lair to participate in the game show.  Don't go whining about it when I cut your legs off and throw you in the lava.  You were my brother.  You were the chosen one.  Now someone else can use those legs.

Why didn't Obi-wan think of all the people who might need a leg transplant, and use the force to save those legs?  Thoughtless.  No wonder Anakin turned.


There can be obi wan.
 
2022-06-26 1:37:57 AM  

Spectrum: IgG4: IgG4: Well is was a genetically engineered pig. Maybe not enough 5G?

A weird side story to this is that they had to get rid of the gene for Alpha Galactose in these pigs to make them immunologically acceptable transplant donors for humans. Alpha Gal is what people how have been bitten by the lone star tick become allergic to and prevents them from eating red meat. So after they harvest the usable organs you still have a whole pig carcass on your hands. So when the company sponsoring this trial was at it the also go licensed as a food production facility to make bacon and pork chops for Alpha Gal sensitive folks.

No no no. None of that is true.


Would you eat that meat though?
https://images.app.goo.gl/mCakJV5XgzZ7QDuLA
Radio Lab episode: alpha gal returns.
 
2022-06-26 2:17:42 PM  

drewogatory: Try putting a few into strong healthy people. Just a thought.


OK, Dr. Mengele.
 
2022-06-26 2:20:31 PM  

dyhchong: drewogatory: Try putting a few into strong healthy people. Just a thought.

Hands up any volunteers.

*crickets*

Although if they can nail the "one foot in the grave" market, it'll take longer to come to market, but the product will be bulletproof when expanded out. They'll see and resolve every unforeseeable issue before it's market ready.


Even if a strong, healthy, normal person seriously wanted to it would be an unethical atrocity to injure and likely kill them with such an experiment.
 
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