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(NL Times (Netherlands))   Cancer vaccine cures ten year old's bone cancer. Now he wants steak. Still no cure f...no, wait?   (nltimes.nl) divider line
    More: Spiffy, Cancer, cancer vaccine, Immune system, Oncology, dogs' chances, research team, important step, Vaccine  
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4230 clicks; posted to Main » on 24 May 2022 at 10:45 AM (6 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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2022-05-24 10:04:25 AM  
Lost my grandfather 19 years ago to bone cancer after he has beat prostate cancer. Hopefully this will lead to something for humans in the near future.
 
2022-05-24 10:14:50 AM  
That'd be so awesome. A cure for goddamed cancer.
 
2022-05-24 10:47:57 AM  
Assuming humanity can put war back in its collective pants,
These next 30 years are going to be amazing for medicine.
 
2022-05-24 10:50:50 AM  

Sub Human: That'd be so awesome. A cure for goddamed cancer.


*One form of cancer.
 
2022-05-24 10:51:30 AM  

Somaticasual: Assuming humanity can put war back in its collective pants,
These next 30 years are going to be amazing for medicine.


Given the extreme headwinds of climate change I don't think less war is in humanities future. Desperate people tend to end up in fight or flight and both actually generally lead to wars.

/Sorry to be Debbie Downer
//Will be very happy to see more cancers go away
///Fark cancer
 
2022-05-24 10:52:53 AM  
I hope i'm still alive when the cure for cancer is announced.  It will be a great day for science.
 
2022-05-24 10:53:10 AM  
There are many different cancers & many causes for them. A single vaccine won't cure all cancer, but if it could cure like 90% of all cancer, or heck even 1-2%, it would save millions of lives.

Huge deal
 
2022-05-24 10:54:08 AM  
The news media is utterly confused about the differences between a vaccine, a treatment and a cure. I blame Trump.
 
2022-05-24 10:57:36 AM  
Best woofday thread ever
 
2022-05-24 10:59:27 AM  

alechemist: Lost my grandfather 19 years ago to bone cancer after he has beat prostate cancer. Hopefully this will lead to something for humans in the near future.


Lost my uncle to bone cancer that spread about 5 years ago. Spent a couple months with him pretty much just the two of us refurbishing my mom's downstairs for my grandmother to live there. We didn't talk much, he sort of leaned Republican as the next in line for Post Master General of the USA and we just didn't talk much - this was before Trump in 2010, he did not make any disparaging remarks about Dems, we talked about individual rights.
 
2022-05-24 11:00:19 AM  
Fark cancer

/insert long diatribe on how much it sucks seeing a child suffer from it
 
2022-05-24 11:02:37 AM  

Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.


**It's a good start
 
2022-05-24 11:07:10 AM  
Lost my dog to liver cancer in 2020, would've given anything for a treatment.

/ Still hate 2020 with the fire of a thousand suns
 
2022-05-24 11:07:22 AM  
Cancer is an umbrella term for many different diseases. This is great, though.
 
2022-05-24 11:07:52 AM  
Rax
by Zidders

A once very sick Malinois
gave to the doctors his fuzzy paw.
A thank you for their new vaccine
upon which all his hopes had leaned.

Made in a lab in Amsterdam.
Part of a now years-long program
this shot affects a bad protein.
One that when active can be quite mean.

It turns off a dog's immune system.
Cancerous tumors then grow within them.
The vaccine takes this protein out.
A new chance is given where there was doubt.

Here's hoping that with this medicine
a cure for more cancers won't be a whim. 
Once more our loyal four-legged friends
are there to face threats and defend.
 
2022-05-24 11:09:11 AM  

Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.


Seemed to be several times according to TFA.
 
2022-05-24 11:10:50 AM  

The Exit Stencilist: Lost my dog to liver cancer in 2020, would've given anything for a treatment.

/ Still hate 2020 with the fire of a thousand suns


I'm sorry, friend. We lost our Ibizan hound Shiner to cancer back in 2011. I wouldn't wish having to go through losing a friend like that on anyone.
 
2022-05-24 11:18:46 AM  

Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.


"The vaccine proved effective in laboratory animals against colorectal cancer, skin cancer, and brain tumors. And now also in spontaneous bladder cancer "
 
2022-05-24 11:19:36 AM  
If the cure for cancer turns out to be a vaccine, 30% of the people will refuse.
 
2022-05-24 11:23:27 AM  

Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.


FTFA: "The vaccine proved effective in laboratory animals against colorectal cancer, skin cancer, and brain tumors. And now also in spontaneous bladder cancer in dogs," said Griffioen.
 
2022-05-24 11:23:43 AM  

johnny_vegas: Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.

**It's a good start


***Agreed.
 
2022-05-24 11:25:10 AM  

To The Escape Zeppelin!: Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.

"The vaccine proved effective in laboratory animals against colorectal cancer, skin cancer, and brain tumors. And now also in spontaneous bladder cancer "


/shakes tiny fist
 
2022-05-24 11:28:52 AM  

alechemist: Lost my grandfather 19 years ago to bone cancer after he has beat prostate cancer. Hopefully this will lead to something for humans in the near future.


I lost a friend who was under 50 to bone cancer.  That a vaccine works even on a dog is impressive as heck.
 
2022-05-24 11:30:14 AM  
That's a quality Fark.com headline right there...well done *rimshot*. ;)
 
2022-05-24 11:47:45 AM  

Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.


Theoretically leading to other versions -  the idea is you teach the immune system that the cancer is bad.

The trick is teaching the immune system that the cancer is bad but that normal cells are not bad.

The issue is that it has to be an individual designed treatment - you need a vaccine that says "Okay, things in your body that have this on them are bad, eat them." But that won't apply to other people's cancers, they'll need one that spots the difference between their normal cells and their particular cancer.

The good news is the ability to both sequence these tissues, spot the difference, and develop a vaccine to train the immune system has gone from "year long effort" to "days"

There are places this can't help - if they can't spot a safe genetic different for a vaccine to train the immune system on, they can't use that therapy, it would either do nothing or create a systemic autoimmune disease (which means now you're more farked.)

Forex, with COVID-19, they had the spike protein that attaches to the ACE2 receptor - it was different enough from the normal enzyme that attaches there that they could build a vaccine that basically said "eat anything with this protein." If there isn't enough of a difference, they can't do that, the immune system would either ignore the vaccine (dude, that's like, all of us!) or worse, not (EAT ALL THE THINGS!)
 
2022-05-24 11:53:25 AM  

Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.


From TFA:
"The vaccine proved effective in laboratory animals against colorectal cancer, skin cancer, and brain tumors. And now also in spontaneous bladder cancer in dogs,"
 
2022-05-24 11:57:29 AM  

WastrelWay: The news media is utterly confused about the differences between a vaccine, a treatment and a cure. I blame Trump.


Yeah, it is confusing.  This is a treatment by vaccination, as opposed to prevention by vaccination.

This is a vaccination because it causes the immune system to attack a protein (vimentin) that is over-expressed in certain kinds of cancer and makes tumors worse.  It doesn't target the tumors themselves or the cause of the tumors, the way vaccinations against bacteria or viruses do, but it is still a form of vaccination.

I suspect this won't be a good preventative vaccine for humans. Vimentin isn't cancer-specific and is crucial to ovum, sperm and fetal development. At the very least, there is a long, steep road ahead to prove that it is safe when used to prevent cancer.

Still, it looks like a promising treatment option for people and animals who have cancer already.  It might even be effective in certain cases of metastatic cancer which is pretty freaking awesome. Should be less terrible than chemotherapy too.
 
2022-05-24 12:15:36 PM  

groverpm: Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.

FTFA: "The vaccine proved effective in laboratory animals against colorectal cancer, skin cancer, and brain tumors. And now also in spontaneous bladder cancer in dogs," said Griffioen.


It will be effective in cancer types that involve the over-expression of vimentin. That is a lot of cancers to be sure, tumors especially.
 
2022-05-24 12:29:08 PM  
FTFA: "
The researchers treated 35 dogs with spontaneous bladder cancer with the vaccine, and half are still alive 400 days later. Two even wholly recovered.
Without treatment, half of the dogs would have died within 180 days and all of them within a year, on average."

If it works that well by itself, it probably greatly increases the odds when combined with other methods... so great step in the right direction, but a universal cure this is very much not.
 
2022-05-24 12:34:39 PM  

Sub Human: That'd be so awesome. A cure for goddamed cancer.


Tell me about it. My youngest sister was just diagnosed with stage 3 breast cancer a couple weeks ago and last week I find out that my other sister is having a biopsy of her uterus. I thought the pandemic was shiat, but the hits just keep on coming.

/ fark cancer
 
2022-05-24 12:39:05 PM  

alechemist: Lost my grandfather 19 years ago to bone cancer after he has beat prostate cancer. Hopefully this will lead to something for humans in the near future.


It already has. Roswell Park Cancer Institute has a vaccine in stage two trials for patients with Glioblastoma, while it doesn't seem to be a cure, in the trials it is showing promise as a treatment to significantly extend the time before  symptoms reappear and death.
For those of you that don't know Glioblastoma is generally fatal in under 18 months (think Gord Downie of the Hip or 3-5 years if you get the rare version, think Neal Peart of Rush).
 
2022-05-24 12:56:34 PM  

DRTFA: If the cure for cancer turns out to be a vaccine, 30% of the people will refuse.


GroguDieTrash.jpg
 
2022-05-24 12:58:07 PM  
64.media.tumblr.comView Full Size
 
2022-05-24 1:09:54 PM  

DRTFA: If the cure for cancer turns out to be a vaccine, 30% of the people will refuse.


Good. Chlorine for the gene pool.

The cured can tapdance past the rooms of the stubborn on their way out of the hospital.
 
2022-05-24 1:20:10 PM  

Fireproof: Sub Human: That'd be so awesome. A cure for goddamed cancer.

*One form of cancer.


RTFA

"The vaccine proved effective in laboratory animals against colorectal cancer, skin cancer, and brain tumors. And now also in spontaneous bladder cancer in dogs," said Griffioen.
 
2022-05-24 1:42:37 PM  

I hereby demand that I be given a Fark account: Theoretically leading to other versions -  the idea is you teach the immune system that the cancer is bad.


It's not teaching the immune system the cancer is bad, it's taking out a protein that prevents the immune system from accessing the tumor at all.

As others have pointed out, it's the same protein that protects our reproductive systems from being targeted by our immune systems, so that could be a downside to the treatment.
 
2022-05-24 1:56:02 PM  

radioactive-hamster: I hereby demand that I be given a Fark account: Theoretically leading to other versions -  the idea is you teach the immune system that the cancer is bad.

It's not teaching the immune system the cancer is bad, it's taking out a protein that prevents the immune system from accessing the tumor at all.

As others have pointed out, it's the same protein that protects our reproductive systems from being targeted by our immune systems, so that could be a downside to the treatment.


Hmm .. chance of sterility or certain death ... I wonder which I'd choose...
 
2022-05-24 2:02:39 PM  

Nick Nostril: Sub Human: That'd be so awesome. A cure for goddamed cancer.

Tell me about it. My youngest sister was just diagnosed with stage 3 breast cancer a couple weeks ago and last week I find out that my other sister is having a biopsy of her uterus. I thought the pandemic was shiat, but the hits just keep on coming.

/ fark cancer


I hope the one recovers and the other is OK. I hope you're OK, too. If it's something that runs in your family it's worth it to get screened. Heck, even if it doesn't.
 
2022-05-24 2:10:31 PM  

DRTFA: If the cure for cancer turns out to be a vaccine, 30% of the people will refuse.


Unlike something like the Covid vaccine, their idiotic decisions only affect themselves since cancer isn't contagious.
 
2022-05-24 2:12:52 PM  

radioactive-hamster: I hereby demand that I be given a Fark account: Theoretically leading to other versions -  the idea is you teach the immune system that the cancer is bad.

It's not teaching the immune system the cancer is bad, it's taking out a protein that prevents the immune system from accessing the tumor at all.

As others have pointed out, it's the same protein that protects our reproductive systems from being targeted by our immune systems, so that could be a downside to the treatment.


90% of cancers hit after 45. It would certainly be VERY useful for postmenopausal women and for men who have no desire to have children.
 
2022-05-24 2:26:14 PM  
Know someone who lost a leg to bone cancer as a kid and took his life when it came back as an adult.

May this vaccine lead to bigger and better things.

And fark cancer.
 
2022-05-24 2:36:55 PM  

meanmutton: DRTFA: If the cure for cancer turns out to be a vaccine, 30% of the people will refuse.

Unlike something like the Covid vaccine, their idiotic decisions only affect themselves since cancer isn't contagious.


Well, except many forms are (HPV and cervical cancer is but the first of quite a few cancers that have been found to be caused/exasperated by a virus).

/The fact that the HPV vaccine isn't more widely used is a crying shame
//Fark the Puritans and all of their spawn
///Letting religious hangups get in the way of sound public policy is a pox against our species
 
2022-05-24 2:42:12 PM  
me: alechemist: Lost my grandfather 19 years ago to bone cancer after he has beat prostate cancer. Hopefully this will lead to something for humans in the near future.

Lost my uncle to bone cancer that spread about 5 years ago. Spent a couple months with him pretty much just the two of us refurbishing my mom's downstairs for my grandmother to live there. We didn't talk much, he sort of leaned Republican as the next in line for Post Master General of the USA and we just didn't talk much - this was before Trump in 2010, he did not make any disparaging remarks about Dems, we talked about individual rights.


I wanted to add to this, my uncle definitely would have hated at least what Trump did with the Post Office, as those sorting machines, remember them? That was the reason why my uncle was supposed to be next Post Master, because that was his pet project.
 
2022-05-24 3:30:03 PM  

MurphyMurphy: Fark cancer

/insert long diatribe on how much it sucks seeing a child suffer from it


you know that 10 year old likes FP play fetch and go for walks right?
 
2022-05-24 4:48:42 PM  

robodog: Somaticasual: Assuming humanity can put war back in its collective pants,
These next 30 years are going to be amazing for medicine.

Given the extreme headwinds of climate change I don't think less war is in humanities future. Desperate people tend to end up in fight or flight and both actually generally lead to wars.

/Sorry to be Debbie Downer
//Will be very happy to see more cancers go away
///Fark cancer


True, but there's about to be a lot more space in Russia, and an increase in need for agricultural workers.
 
2022-05-24 4:52:31 PM  

DRTFA: If the cure for cancer turns out to be a vaccine, 30% of the people will refuse.


Fine.
 
2022-05-24 6:51:36 PM  

zidders: Nick Nostril: Sub Human: That'd be so awesome. A cure for goddamed cancer.

Tell me about it. My youngest sister was just diagnosed with stage 3 breast cancer a couple weeks ago and last week I find out that my other sister is having a biopsy of her uterus. I thought the pandemic was shiat, but the hits just keep on coming.

/ fark cancer

I hope the one recovers and the other is OK. I hope you're OK, too. If it's something that runs in your family it's worth it to get screened. Heck, even if it doesn't.


Thanks. My sisters are telling me that even as a male, I need to get the genetic test.
 
2022-05-24 7:42:49 PM  

Sub Human: That'd be so awesome. A cure for goddamed cancer.


Now if we could cure Republicanism...
 
2022-05-25 2:32:08 PM  

Baloo Uriza: Sub Human: That'd be so awesome. A cure for goddamed cancer.

Now if we could cure Republicanism...


That's a job for the psychiatrists not immunologists.
 
2022-05-25 3:14:10 PM  

awruk!: Baloo Uriza: Sub Human: That'd be so awesome. A cure for goddamed cancer.

Now if we could cure Republicanism...

That's a job for the psychiatrists not immunologists.


Are we sure they don't have the brain worms?
 
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