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(Science Alert)   Taking Tylenol linked to risky behavior, unlike the alcohol that gave you the hangover in the first place   (sciencealert.com) divider line
    More: Interesting, Risk, Over-the-counter drug, Paracetamol, Psychology, Codeine, important effects, seriousness of those findings, Emotion  
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3343 clicks; posted to Main » on 20 Nov 2021 at 6:35 AM (25 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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2021-11-20 12:25:45 AM  
That shiat's supposed to be bad for your liver so don't take it if you're already a drunk.
 
2021-11-20 12:51:05 AM  

Mugato: That shiat's supposed to be bad for your liver so don't take it if you're already a drunk.


And it's no better than a placebo for treating lower back pain.
 
2021-11-20 12:57:51 AM  

Ivo Shandor: Mugato: That shiat's supposed to be bad for your liver so don't take it if you're already a drunk.

And it's no better than a placebo for treating lower back pain.


We are truly servents of the public good.
 
2021-11-20 1:54:47 AM  
what is, autocorrelation?
 
2021-11-20 6:41:02 AM  
True story:

Thursday, I had the VERY rare second martini.  Immediately regretted my indiscretion.  Took a shower and went to bed at 9pm.

Woke up two hours later with a BUSTING headache, so I got up, took two Tylenol and drank a huge glass of water.

30 minutes later, my fiance is pregnant.  I blame the Tylenol.

/Ok..that last part isn't true.
//If it WERE true, I'd prob slit my own wrists
 
2021-11-20 6:45:55 AM  
I make it a point to Not consume alcohol and tylenol within 24h of each other. They're toxic together. If you want to prevent a hangover, take 1 milk thistle for every 3-4 beers. If you don't have milk thistle, eat candy after you're drunk. Otherwise, a cajun filet biscuit combo from Bojangles, a large sweet tea and a nap shortly after will do the trick.
 
2021-11-20 6:48:05 AM  
I'd just like to take this moment to say I love Tylenol II's.

Caffeine, codeine, and acetaminophen all in one wonderful little pill available over the counter*.

*offer not valid for the USA
 
2021-11-20 6:54:53 AM  
Tylenol? What is it?
 
2021-11-20 7:02:48 AM  

Boo_Guy: I'd just like to take this moment to say I love Tylenol II's.

Caffeine, codeine, and acetaminophen all in one wonderful little pill available over the counter*.

*offer not valid for the USA


** or Sweden, where the middle one is now narkotika-class, and therefore shall only be talked about in hushed tones, much like cannabinoids, and other life-threatening substances.

/lutfisk season is already upon us, ffs.
 
2021-11-20 7:06:41 AM  
everyone knows that 5mg adderall + 800 mg ibuprofen makes you right as rain.
 
2021-11-20 7:13:30 AM  
Back when I was drinking to excess on a regular basis, I avoided Tylenol on a friend's advice (friend is an RN).

I found a bong rip to be quite helpful.

YMMV
 
2021-11-20 7:23:08 AM  

Ivo Shandor: Mugato: That shiat's supposed to be bad for your liver so don't take it if you're already a drunk.

And it's no better than a placebo for treating lower back pain.


Lower back pain is just youth leaving the body.
 
2021-11-20 7:23:11 AM  

The Official Fark Cajun: True story:

Thursday, I had the VERY rare second martini.  Immediately regretted my indiscretion.  Took a shower and went to bed at 9pm.

Woke up two hours later with a BUSTING headache, so I got up, took two Tylenol and drank a huge glass of water.

30 minutes later, my fiance is pregnant.  I blame the Tylenol.

/Ok..that last part isn't true.
//If it WERE true, I'd prob slit my own wrists


How do you know it is wasn't the water?!

/and why would you slit your wrists?
 
2021-11-20 7:25:54 AM  

Resident Muslim: The Official Fark Cajun: True story:

Thursday, I had the VERY rare second martini.  Immediately regretted my indiscretion.  Took a shower and went to bed at 9pm.

Woke up two hours later with a BUSTING headache, so I got up, took two Tylenol and drank a huge glass of water.

30 minutes later, my fiance is pregnant.  I blame the Tylenol.

/Ok..that last part isn't true.
//If it WERE true, I'd prob slit my own wrists

How do you know it is wasn't the water?!

/and why would you slit your wrists?


Maybe they live in Texas.
 
2021-11-20 7:27:46 AM  
I had about a third of a bottle of rum last night.  I don't have a hangover because I ate before and had a little food after and drank plenty of water.  Only with rum can I get away with that anymore.
 
2021-11-20 7:28:51 AM  
Tylenol and aspirin are the only analgesics, other than like, Mobic, that do anything for my pain or inflammation. And having just taken both, and had a nice cup of coffee, I'm enjoying this thread.

/Cortisone injections in the hand are hurty
 
2021-11-20 7:29:04 AM  

Lady J: what is, autocorrelation?


Please explain.

/feel like I haven't seen your username in a while
//also, FTA: "While the effects might be slight", how slight? Also, should have given people something that actually IS risky, even if it's just $5 that they then could lose, not a balloon on a screen. You know damn well people would start extrapolating from this all things like wreckless behavior to road rage smashing into others' cars *insert news cycle cartoon here*
///that wasn't a typo
 
2021-11-20 7:30:38 AM  
Tylenol and alcohol causes liver failure.

Fark user imageView Full Size
 
2021-11-20 7:36:17 AM  

LewDux: Tylenol? What is it?


It's white and red and looks like a big airplane.
 
2021-11-20 7:38:44 AM  
From a neuropsychiatric perspective Tylenol might not be all that benign. https://www.nih.gov/news-events/news-releases/nih-funded-study-suggests-acetaminophen-exposure-pregnancy-linked-higher-risk-adhd-autism

Of course that study suffers from correlation doesn't equal causation. The woman could have taken more acetaminophen due to having more pregnancy complications, poorer health etc. Still I stay away from the stuff.  Tend to use naproxen when needed.
 
2021-11-20 7:40:27 AM  

BlippityBleep: Ivo Shandor: Mugato: That shiat's supposed to be bad for your liver so don't take it if you're already a drunk.

And it's no better than a placebo for treating lower back pain.

Lower back pain is just youth leaving the body.


And saying, "Hello, darlin', welcome to the second half of your life!"
 
2021-11-20 7:40:43 AM  

Resident Muslim: Lady J: what is, autocorrelation?

Please explain.

/feel like I haven't seen your username in a while
//also, FTA: "While the effects might be slight", how slight? Also, should have given people something that actually IS risky, even if it's just $5 that they then could lose, not a balloon on a screen. You know damn well people would start extrapolating from this all things like wreckless behavior to road rage smashing into others' cars *insert news cycle cartoon here*
///that wasn't a typo


See the correlations with prenatal exposure and ADHD/autism. There might be something neuropsychiatric to acetaminophen. It is interesting that effects are seen in adults.
 
2021-11-20 7:41:42 AM  
I have said this before, but it bares repeating. About 40 years ago, I worked with a husband and wife that really liked drinking. One night, after a particularly hard session, she decided to get a head start on the hangover, and took a bunch of Tylenol before going to bed. She never woke up. I still remember her name.
 
2021-11-20 7:42:30 AM  

tuxq: I make it a point to Not consume alcohol and tylenol within 24h of each other. They're toxic together. If you want to prevent a hangover, take 1 milk thistle for every 3-4 beers. If you don't have milk thistle, eat candy after you're drunk. Otherwise, a cajun filet biscuit combo from Bojangles, a large sweet tea and a nap shortly after will do the trick.


You'll die from the hangover long before you get to the drivethru window, unless your Bojangles actually has an open lobby. None (that I've run across) in 3 states do.
 
2021-11-20 7:43:05 AM  
TFG comes out favor on Tylenol in 3... 2....
 
2021-11-20 7:46:15 AM  

uttertosh: Boo_Guy: I'd just like to take this moment to say I love Tylenol II's.

Caffeine, codeine, and acetaminophen all in one wonderful little pill available over the counter*.

*offer not valid for the USA

** or Sweden, where the middle one is now narkotika-class, and therefore shall only be talked about in hushed tones, much like cannabinoids, and other life-threatening substances.

/lutfisk season is already upon us, ffs.


It's not all bad, surströmming season is over.
 
2021-11-20 7:52:11 AM  

tuxq: I make it a point to Not consume alcohol and tylenol within 24h of each other. They're toxic together. If you want to prevent a hangover, take 1 milk thistle for every 3-4 beers. If you don't have milk thistle, eat candy after you're drunk. Otherwise, a cajun filet biscuit combo from Bojangles, a large sweet tea and a nap shortly after will do the trick.


My magic hangover cure is to drink a litre of water mixed with a tablespoon of sugar, teaspoon of table salt and a pinch of bicarb, and eat a quarter of banana before bed. Then, eat and drink that again when you wake up. The hangover goes away enough in 20 minutes to enable me to easily get back to sleep off the rest of it.

Of course it may have more to do with the (at least) 120mg of codeine or its equianalgesic I take with the second drink that really lets me get back to sleep and takes away the pains.
 
2021-11-20 8:04:08 AM  

Ivo Shandor: Mugato: That shiat's supposed to be bad for your liver so don't take it if you're already a drunk.

And it's no better than a placebo for treating lower back pain.


When I had kidney stones they prescribed me some extra strength generic tylenol. It didn't do crap. Two regular advil were much better.

I doubt any effectiveness of tylenol for anything, at least for me. It never seems to help.
 
2021-11-20 8:14:07 AM  
When I was 8, the first Tylenol poisoning case happened near where I lived. I know it's irrational, but I'm still leery of taking it

https://en.wikipedia.org/wiki/Chicago_Tylenol_murders
 
2021-11-20 8:16:44 AM  

The_Homeless_Guy: Resident Muslim: Lady J: what is, autocorrelation?

Please explain.

/feel like I haven't seen your username in a while
//also, FTA: "While the effects might be slight", how slight? Also, should have given people something that actually IS risky, even if it's just $5 that they then could lose, not a balloon on a screen. You know damn well people would start extrapolating from this all things like wreckless behavior to road rage smashing into others' cars *insert news cycle cartoon here*
///that wasn't a typo

See the correlations with prenatal exposure and ADHD/autism. There might be something neuropsychiatric to acetaminophen. It is interesting that effects are seen in adults.


Sorry, I should have clarified, 1) I don't know what autocorrelation means 2) how would that apply here.
As for exposure and autism, it would be interesting to read, especially since I've previously said to people to consider that painkillers work on the brain, not the actual area that hurts.

/for some reason reminds me of my very, uhm, "dedicated" boss who, when I implied something, stated "I don't do that...my body is my temple."
//my reply was "me too! A Roman temple."
///he wasn't amused
 
2021-11-20 8:27:37 AM  

Resident Muslim: The_Homeless_Guy: Resident Muslim: Lady J: what is, autocorrelation?

Please explain.

/feel like I haven't seen your username in a while
//also, FTA: "While the effects might be slight", how slight? Also, should have given people something that actually IS risky, even if it's just $5 that they then could lose, not a balloon on a screen. You know damn well people would start extrapolating from this all things like wreckless behavior to road rage smashing into others' cars *insert news cycle cartoon here*
///that wasn't a typo

See the correlations with prenatal exposure and ADHD/autism. There might be something neuropsychiatric to acetaminophen. It is interesting that effects are seen in adults.

Sorry, I should have clarified, 1) I don't know what autocorrelation means 2) how would that apply here.
As for exposure and autism, it would be interesting to read, especially since I've previously said to people to consider that painkillers work on the brain, not the actual area that hurts.

/for some reason reminds me of my very, uhm, "dedicated" boss who, when I implied something, stated "I don't do that...my body is my temple."
//my reply was "me too! A Roman temple."
///he wasn't amused


That was a typo sorry. Hate using phones.
 
2021-11-20 8:27:45 AM  
My hangover cure is to sit in a darkened room for two days sipping water.  I don't drink very much anymore.
 
2021-11-20 8:35:47 AM  
I rarely take painkillers, or any drugs really.  All kinds of reasons really, I'm not moralizing here, maybe I just don't need them all that much.

- I don't like my mind altered, my thinking/decision making processes changed.  So no recreational drugs/alcohol.
- Anti inflammatory drugs such as Motrin, actually impede the bodies repair of ligament damage.  The inflammation is a call for healing of the affected bits.
- Tylenol, I might take once a year for a severe headache, but as often as not, I just drink some water and take a nap, and wake up better.
- Liver health matters, I watched two good friends die of cirrhosis. Not a pretty way to go.
- My knees are trashed, and always in pain.  I have plantar fasciitis.  It's very painful to move for the first half our or so after rest.  I take half an hour to slowly hobble about and to stretch out the feet, then I can hike/climb mountains all day.  The pain just fades to the background, and I can ignore it.  Exercise is a great painkiller.

When I was much younger and muscle'y my back was always going out, and I took all sorts of pain medications and it always seemed like a never ending cycle of pain and relief.  Again, purely anecdotal, and based on my body/my experience.  YMMV.
 
2021-11-20 9:11:30 AM  
I'm pretty sure it's the other way around:  Risky behavior is linked to Tylenol use.
 
2021-11-20 9:15:31 AM  
If I'm going to overindulge, besides getting a dd, I will drink a leader of Pedialyte and get another for the next morning.
 
2021-11-20 9:18:08 AM  
I try to stay away from any and all pills and medicines, because I have to take blood pressure medication.  I'm constantly worried about negative interactions between the two, and getting my blood pressure under control is my primary concern.  My medicine cabinet is down to beano, pepto-bismol, tylenol, and zyrtec, because those don't supposedly interact with the blood pressure medication.  Even then, they're only for emergencies and not regular use (except for my daily zyrtec).
 
2021-11-20 9:18:17 AM  

eclecticman666: If I'm going to overindulge, besides getting a dd, I will drink a leader of Pedialyte and get another for the next morning.


Litter of Pedialyte.

They also have it in powdered form, which I keep in the cupboard for those times I didn't know I was going to over indulge.
 
2021-11-20 9:22:38 AM  
"HA HA I drink so much that it makes me feel sick and so I joke about it on FARK to feel better about it!"
 
2021-11-20 9:23:54 AM  

LewDux: Tylenol? What is it?


It is a delivery vector for cyanide, much like celery is for Cheez Whiz.
 
2021-11-20 9:24:08 AM  
Fun fact that Acetaminophen is a mood suppressor.

Which means it really can help with the pain of a broken heart.
 
2021-11-20 9:24:39 AM  
I drink to excess, all the time. Havent taken tylenol in over a decade. This thread makes me think that is a good idea
 
2021-11-20 9:49:08 AM  
Makes me think of the guy in "In Cold Blood" who was addicted to aspirin - chewed it up by the bottle because of leg pain.  There was definitely something wrong with his head too.
 
2021-11-20 9:57:41 AM  

eclecticman666: eclecticman666: If I'm going to overindulge, besides getting a dd, I will drink a leader of Pedialyte and get another for the next morning.

Litter of Pedialyte.

They also have it in powdered form, which I keep in the cupboard for those times I didn't know I was going to over indulge.


One more try!  I believe in you!
 
2021-11-20 10:14:42 AM  
I'm curios about the demographics of Tylenol users. 25% of the population uses it regularly and it lowers empathy.  Seems like that could explain some things.
 
2021-11-20 10:15:35 AM  

Resident Muslim: The Official Fark Cajun: True story:

Thursday, I had the VERY rare second martini.  Immediately regretted my indiscretion.  Took a shower and went to bed at 9pm.

Woke up two hours later with a BUSTING headache, so I got up, took two Tylenol and drank a huge glass of water.

30 minutes later, my fiance is pregnant.  I blame the Tylenol.

/Ok..that last part isn't true.
//If it WERE true, I'd prob slit my own wrists

How do you know it is wasn't the water?!

/and why would you slit your wrists?


Because I'm 44.  The thought of having a ball and chain for another 18 years minimum is enough for me to plan an out.
 
2021-11-20 10:31:42 AM  

The Official Fark Cajun: Resident Muslim: The Official Fark Cajun: True story:

Thursday, I had the VERY rare second martini.  Immediately regretted my indiscretion.  Took a shower and went to bed at 9pm.

Woke up two hours later with a BUSTING headache, so I got up, took two Tylenol and drank a huge glass of water.

30 minutes later, my fiance is pregnant.  I blame the Tylenol.

/Ok..that last part isn't true.
//If it WERE true, I'd prob slit my own wrists

How do you know it is wasn't the water?!

/and why would you slit your wrists?

Because I'm 44.  The thought of having a ball and chain for another 18 years minimum is enough for me to plan an out.


So you had a kid before turning 27?
"Another"
Once bitten, I take it.

/was surprised because I'm (REALLY) old-fashioned and always assume fiancée is just a run up to kids, so was surprised by your response, and now I'm thinking of to how many people that's normal
//oh, and my eldest is third year university
///and my youngest *smiles* just past toddler stage. After 8 years...my wife wasn't amused :)
 
2021-11-20 10:37:44 AM  
Journalists (and publicists) will naturally always present correlations in the order that catches our attention. When you see a headline "X linked to Y", it's always a good idea to rearrange X and Y to see if the result is less surprising that way.

"Risky behavior linked to taking Tylenol"

Well well well, that's not much of a surprise.

Who known which way the cause & effect goes, but "risky behavior increases Tylenol intake" sounds quite reasonable and may well explain at least a part of the effect.
 
2021-11-20 10:38:35 AM  

WilderKWight: "HA HA I drink so much that it makes me feel sick and so I joke about it on FARK to feel better about it!"


"HA HA I post judgemental comments on Fark as I am way more intelligent than all you assholes."
/GFY
 
2021-11-20 10:47:51 AM  

vilesithknight: I drink to excess, all the time. Havent taken tylenol in over a decade. This thread makes me think that is a good idea


Yes.

Refresher for the class: Acetaminophen/Paracetamol strips the liver clean of Glutathione, one of its main detox enzymes. Glutathione is very important to your body and liver! Tylenol is POISON and always has been. Your body needs a lot of time to restock that Glutathione and while it's gone, all metabolic byproducts that are toxic (especially alcohol) will now be actively killing you because your body can't get rid of them by converting them into bile. Meanwhile you are also now busy damaging your kidneys because they try to flush what the liver can't and that's not how they are supposed to work: people with bad livers tend to die first from renal failure.

The only remedy is massive amounts of N-Acetyl L-Cystine (orally and intravenously) and Glutathione intravenously. Your body cannot absorb more than like 1% of Glutathione orally so taking N-A-C as the precursor that your body CAN take orally is a good idea if you absolutely must take a lot of Tylenol for any reason.
Again, Tylenol is POISON and doctors and the makers have always known this. The dose makes the poison and that dose is very low compared to other things like Aspirin.

Now for the really bad news: good luck trying to get ahold of NAC in the United States now, as the FDA is currently reviewing it for removal from the OTC supplement market because some assshole Big Pharma company complained to the FDA about this nearly 60 year old product because once upon a time it was a patented medicine, and apparently nothing that has ever been sold as a medicine can ever be allowed to be sold as a "supplement". Jarrow and Now have already ceased making it and the market is drying up here in the States. Keep your eyes peeled for a new NAC-based medicine in the coming months or years.
 
2021-11-20 10:57:04 AM  
I gather my taking a low dose aspirin daily on doctor's prescription is risk reduction rather than reduced risk perception.  The absurdly higher cost of the low dose aspirin risks my pocket money enough that I split a regular tablet in quarters instead too, same dose.
 
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