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(Stat News)   The largest trial yet confirms shroomin' is boomin' when you're dark roomin'   (statnews.com) divider line
    More: Spiffy, Suicide, Major depressive disorder, Phase 2b study, treatment-resistant depression, Bipolar disorder, part of the study, suicidal behavior, highest dose  
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772 clicks; posted to STEM » on 11 Nov 2021 at 3:01 PM (28 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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2021-11-11 2:28:36 PM  
"The suicidal behaviors were reported at least one month after the administration of treatment and they occurred in patients who were essentially non-responding,"

True, I guess I'd be even more Eeyore-feeling when the miracle mushrooms don't help.

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2021-11-11 3:26:04 PM  
There is nothing quite like the ego-shattering introspection that only a mushroom trup can open your mind to.
 
2021-11-11 3:37:32 PM  
I laugh to the point of almost peeing myself
 
2021-11-11 6:14:05 PM  

MurphyMurphy: I laugh to the point of almost peeing myself


When I have partaken, I laugh until my face hurts. They also seem to make me yawn quite a bit.
 
2021-11-11 10:41:46 PM  
"Everyone agrees such a result hasn't been seen before in depression research, so we're incredibly happy with that result," said Lars Christian Wilde, co-founder and president of Compass.

Well, *somebody* is high on their own supply.
 
2021-11-12 6:13:22 AM  
FTFA:  "The results released by the company, which have not been published in a medical journal or peer-reviewed,..."

Score one for their reliability.

FTFA continued:  "...included side effects data showing a small number of serious adverse events. Overall, 12 patients [over five percent of the total number tested] reported treatment-emergent serious adverse events, five of whom were in the 25-milligram group and six in the 10-milligram group; these included suicidal behavior and self-injury. Just one patient in the 1-milligram [placebo] group experienced a serious adverse event."

So this stuff can be unpredictable?  What a surprise, considering that clinical experiments for this application back in the '50s and '60s with another hallucinogen, LSD, failed to launch because that drug was unpredictable too.

Veloram: There is nothing quite like the ego-shattering introspection that only a mushroom trup can open your mind to.


I bet you that nothing would be better for people suffering from severe depression than to have their egos shattered.
 
2021-11-12 7:38:00 AM  
Good news, but Compass is a profit-driven company that ran a close trial with a non-disclosure agreement. I trust him about as far as I can pick him up and throw them, which given that they are a corporate entity isn't isn't very far.

I think psjlo probably works, but this is low quality evidence at best. They have a huge profit motive.
 
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