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(Sci Tech Daily)   If you suffer from gout, you may want to refill your prescription before freshly-dewormed anti-vaxxers find out your pills help prevent COVID and the flu   (scitechdaily.com) divider line
    More: Interesting, Virus, In vivo, Antiviral drug, Influenza, Infection, In vitro, clinical development, pharmaceutical company TrippBio  
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946 clicks; posted to STEM » on 13 Sep 2021 at 11:20 PM (6 days ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



27 Comments     (+0 »)
View Voting Results: Smartest and Funniest
 
6 days ago  
I hope they take colchicine instead
 
6 days ago  
Oh, geez. My friends with gout describe it as sheer agony. If there's a shortage of treatments, more agony.
 
6 days ago  

mofa: Oh, geez. My friends with gout describe it as sheer agony. If there's a shortage of treatments, more agony.


I have gout. Flare-ups are pure hell.  If it's in your foot, chances are your big toe will get swollen and very red.  Even a sheet touching it in bed is excruciating.  I am currently having a flare-up in my wrist and thumb. I thought I had carpal tunnel.  15mg of oxy doesn't even touch it.  I basically had to follow that with a muscle relaxer and a lot of thc just to get to sleep for a couple of hours.  And even while sleeping you feel the pain.  Anti-inflammatories help it a great deal, but they take time to work.

Not fun. Not fun at all.
 
6 days ago  
These are test tube and small organism results - it's a good ways from proof of any antiviral properties that would affect COVID I think.  Similar results were found for hydroxychoriquin and ivermection, in terms of in vivo and in vitro studies.
But subby is right, the dummies will probably latch on to this now. At least is does have antiviral properties.
 
6 days ago  

mofa: Oh, geez. My friends with gout describe it as sheer agony. If there's a shortage of treatments, more agony.


That's the colchicine. The directions are literally take it until the diarrhea starts then stop immediately or you could die.

The article is about a different med.
If it stands up to scrutiny, fine.

I'm going to sit back and wait for the first story of someone who shiat themselves to death rather than get vaccinated.
 
6 days ago  
It protects you from the covid and helps your liver, Carter's Little Liver Pills. Plus you will never have constipation while taking one each day. Yes folks, Carter's Little Liver Pills are the only sure way to protect you in this big pandemic. Do not forget the great pooping part!
 
6 days ago  
I swear to f*cking God these assholes are intentionally trying to make my job harder.

I feel personally attacked.
 
6 days ago  
"There's really nothing out there to safely fight these viruses,"

I mean, aside from 3 vaccines (one with full FDA approval), monoclonal antibodies, and Remdesivir, he's right.  Oh, and masks, washing your hands, and staying 6ft away from potential carriers.

Yup, nothing exists to prevent or treat COVID.
 
6 days ago  

enry: "There's really nothing out there to safely fight these viruses,"

I mean, aside from 3 vaccines (one with full FDA approval), monoclonal antibodies, and Remdesivir, he's right.  Oh, and masks, washing your hands, and staying 6ft away from potential carriers.

Yup, nothing exists to prevent or treat COVID.


Also...

Fark user imageView Full Size


Oh yeah... it's on allocation now and I can't get any.
 
6 days ago  

NewportBarGuy: enry: "There's really nothing out there to safely fight these viruses,"

I mean, aside from 3 vaccines (one with full FDA approval), monoclonal antibodies, and Remdesivir, he's right.  Oh, and masks, washing your hands, and staying 6ft away from potential carriers.

Yup, nothing exists to prevent or treat COVID.

Also...

[Fark user image image 288x216]

Oh yeah... it's on allocation now and I can't get any.


Monoclonal antibody.  Should have said there's at least two different kinds.
 
6 days ago  
Anti-vaxxers in the future:

c.tenor.comView Full Size
 
6 days ago  
I'm hoping that the miracle treatment next week is injecting roundup.
 
6 days ago  
Gout is sheer hell. The only thing worse is a kidneystone attack. I have both. Hydrocodone is effective for the pain.

Over the past few years, I have been able to greatly reduce the occurrence of gout attacks by taking regular supplements of potassium citrate and guanefesin.  Both the citrate and guan have the side effect of reducing uric acid levels in the blood. With asthma, guan also thins mucus so I take it for that anyway.

Since having bariatric sleeve surgery in January, that has also really cut down on the attacks.

I don't take prescription gout meds, since my doc tells me the first line meds can cause initial flareups as they flush the crap out of your system. Dunno if that is colchicine or probenecid or both or neither.

But if probenecid fights C19 and its cheap and available, I'm all for it. Anything to keep people out of the hospital and off the patriotic choking noises on ventilators.
 
6 days ago  
In a sane timeline this would only be available for people who are vaccinated. Or cost a thousand dollars per pill if you're not.
 
6 days ago  

Somacandra: Gout is sheer hell. The only thing worse is a kidneystone attack. I have both. Hydrocodone is effective for the pain.

Over the past few years, I have been able to greatly reduce the occurrence of gout attacks by taking regular supplements of potassium citrate and guanefesin.  Both the citrate and guan have the side effect of reducing uric acid levels in the blood. With asthma, guan also thins mucus so I take it for that anyway.

Since having bariatric sleeve surgery in January, that has also really cut down on the attacks.

I don't take prescription gout meds, since my doc tells me the first line meds can cause initial flareups as they flush the crap out of your system. Dunno if that is colchicine or probenecid or both or neither.

But if probenecid fights C19 and its cheap and available, I'm all for it. Anything to keep people out of the hospital and off the patriotic choking noises on ventilators.


I don't know the last time we dispensed probenicid at my pharmacy, but we dispense a fair amount of colchicine and a lot of allopurinol.  When I read the headline I assumed it was allopurinol, and that we'd see yet another shortage like so many things in the last couple of years.
 
6 days ago  
I wonder when they'll realize that the people telling them that kind of shiate are literally trying to murder them?  Antivax are bad enough but people talking these idiots into poisoning themselves...  Who needs depopulation conspiracy theories when you can just get them to kill themselves directly?  My neighbor is a dyed in the wool "God doesn't want me wearing a mask" antivaxer.  I wonder how long til he's contacting the local vet about getting his pet goats de-wormed...  Heh, knowing him, he's already done it.
 
6 days ago  

NewportBarGuy: enry: "There's really nothing out there to safely fight these viruses,"

I mean, aside from 3 vaccines (one with full FDA approval), monoclonal antibodies, and Remdesivir, he's right.  Oh, and masks, washing your hands, and staying 6ft away from potential carriers.

Yup, nothing exists to prevent or treat COVID.

Also...

[Fark user image 288x216]

Oh yeah... it's on allocation now and I can't get any.


Was there some sort of MSM/OAN thing on Tocilizumab relatively recently? Because I've been following the pre-pubs and pubs on it and other IL-6 inhibitors since the Italians raised the flag in March 2020 going 'hey ER guys!' But suddenly a buddy from NC, who was popping illegally prescribed HCQ back then (she's moved on to snorting povidone iodine now or something, so baby steps) and ignoring what I was saying about IL-6 inhibitors texting me about this miracle RA drug that is apparently doing wonders treating COVID, saying it's the first she's ever heard of an RA drug treating COVID.
 
5 days ago  

threnodyj: NewportBarGuy: enry: "There's really nothing out there to safely fight these viruses,"

I mean, aside from 3 vaccines (one with full FDA approval), monoclonal antibodies, and Remdesivir, he's right.  Oh, and masks, washing your hands, and staying 6ft away from potential carriers.

Yup, nothing exists to prevent or treat COVID.

Also...

[Fark user image 288x216]

Oh yeah... it's on allocation now and I can't get any.

Was there some sort of MSM/OAN thing on Tocilizumab relatively recently? Because I've been following the pre-pubs and pubs on it and other IL-6 inhibitors since the Italians raised the flag in March 2020 going 'hey ER guys!' But suddenly a buddy from NC, who was popping illegally prescribed HCQ back then (she's moved on to snorting povidone iodine now or something, so baby steps) and ignoring what I was saying about IL-6 inhibitors texting me about this miracle RA drug that is apparently doing wonders treating COVID, saying it's the first she's ever heard of an RA drug treating COVID.


I only know that the ID people totally love this thing for advanced Covid cases in the ICU and go with it before intubation. So, to not be able to buy it for them is making me mad.

Genentech took all supply from the distributors about 8 months ago to handle all deliveries themselves. Then Delta hit. Then they farked up every order/got overwhelmed and cancelled orders and freaked out. Then they gave it back to the drug distributors but put an allocation on it based on purchases from 2019... you know before Covid. So, magically everyone's allocation is zero.

We all think they are selling it out the back door to Texas/Florida/Redneck Riviera... because by the time we all needed it, Delta has been rocking all of them and they probably made a f*cking fortune selling it all to them.
 
5 days ago  
Good news anti vaxxers! There is something the that cures covid that the government doesn't want you to know
imgs.xkcd.comView Full Size

Best of all, you probably already have this medicine in your home.
 
5 days ago  

RodneyToady: mofa: Oh, geez. My friends with gout describe it as sheer agony. If there's a shortage of treatments, more agony.

I have gout. Flare-ups are pure hell.  If it's in your foot, chances are your big toe will get swollen and very red.  Even a sheet touching it in bed is excruciating.  I am currently having a flare-up in my wrist and thumb. I thought I had carpal tunnel.  15mg of oxy doesn't even touch it.  I basically had to follow that with a muscle relaxer and a lot of thc just to get to sleep for a couple of hours.  And even while sleeping you feel the pain.  Anti-inflammatories help it a great deal, but they take time to work.

Not fun. Not fun at all.


My father had it and used to get it in his foot all the time.  I remember him screaming in agony if anything so much as brushed up against his foot on a flare-up.  He nearly killed the dog one day when her tail hit him.  He used to have to crawl to move around the house because there was no putting pressure on it.  There weren't a lot of readily available pain killers back then (70s/80s) like there is now but I do remember him taking Valium when it was bad.
 
5 days ago  
Just imagine if someone convinced them a laxative was the cure all.
 
5 days ago  
Wait, I thought they didn't trust/want to make 'big pharma' richer.

How is this different now?
Somebody making this stuff in their back yard? Is that the qualifier?
 
5 days ago  
If they touch my Allopurinol, I'm gonna have to cut somebody.
 
5 days ago  
I'm on board with everything stated about gout.  It freaking sucks, and I'm no stranger to pain (former marathoner, back surgery, chronic ear infections as a child, and so on.  But I started taking this, 4x a day during a flare up and 2x per day otherwise, and I have not had gout in 4 months.  Despite some IPAs, pork, and scotch, all of which tend to give me flare-ups historically.  Try this, for serious.  It genuinely worked for me.https://smile.amazon.com/Cherry-Ex​trac​t-Strength-Veggie-Potent/dp/B07CTKPKSX​?pd_rd_w=wugmM&pf_rd_p=ba22ea03-d3c1-4​ebb-8d3e-472aa0cf3b30&pf_rd_r=WBRB6C2P​7SAG509188JP&pd_rd_r=1cd0db9c-676d-4a3​7-a80e-beba29b172e2&pd_rd_wg=AMBIp&pd_​rd_i=B07CTKPKSX&psc=1&ref_=pd_bap_d_rp​_13_t
 
5 days ago  

MoriartyLives: I'm on board with everything stated about gout.  It freaking sucks, and I'm no stranger to pain (former marathoner, back surgery, chronic ear infections as a child, and so on.  But I started taking this, 4x a day during a flare up and 2x per day otherwise, and I have not had gout in 4 months.  Despite some IPAs, pork, and scotch, all of which tend to give me flare-ups historically.  Try this, for serious.  It genuinely worked for me.https://smile.amazon.com/Cherry-Ext​ract-Strength-Veggie-Potent/dp/B07CTKP​KSX?pd_rd_w=wugmM&pf_rd_p=ba22ea03-d3c​1-4ebb-8d3e-472aa0cf3b30&pf_rd_r=WBRB6​C2P7SAG509188JP&pd_rd_r=1cd0db9c-676d-​4a37-a80e-beba29b172e2&pd_rd_wg=AMBIp&​pd_rd_i=B07CTKPKSX&psc=1&ref_=pd_bap_d​_rp_13_t


My FIL never quite got to the point where he needed medicated for gout (yet!), but he hasn't had a serious flare-up since he started regularly drinking tart cherry juice. Either Knudsen or Lakewood brand. Not sure which.

The last study that I read said it showed no effect at up to 30ml twice a day though.  I have no idea how much he's drinking.  Probably more than about 4oz though.

Keeps him from complaining anyways.
 
5 days ago  

mofa: Oh, geez. My friends with gout describe it as sheer agony. If there's a shortage of treatments, more agony.


it's only 1 of the two major anti uric med's out there.  Allopurinol is another and is cheaper.
 
5 days ago  

cretinbob: I hope they take colchicine instead


colchicine is no joke.  even when taken properly, you can only take so much of it.  take no more than x amount per day and "Stop taking this medicine as soon as the pain is relieved or at the first sign of nausea, vomiting, stomach pain, or diarrhea.
 
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