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(Twitter)   Oh nothing, just Eric Feigl-Ding explaining the DoD funded dialysis filter that can remove the SARS-Cov-2 virus from a person's body   (twitter.com) divider line
    More: Spiffy, shot  
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771 clicks; posted to STEM » on 12 Apr 2021 at 4:20 PM (4 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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View Voting Results: Smartest and Funniest
 
2021-04-12 3:56:56 PM  
Original Tweet:

 
2021-04-12 4:03:31 PM  
Dayum! That is amazing.
 
2021-04-12 4:07:45 PM  
That's cool. What does it do in terms of survivability and at what level of infection? How soon can we push this out everywhere?
 
2021-04-12 4:07:49 PM  
That is farking cool.
 
2021-04-12 4:12:05 PM  
Wow
 
2021-04-12 4:16:20 PM  
That's damned amazing! I guess all of those billions of dollars we sink into DARPA are paying off a bit.
 
2021-04-12 4:17:35 PM  
Something about that doesn't add up. Coronavirus is way too big to diffuse out of a standard dialysis cartridge. Those are meant to let out very small molecular weight waste products. If you made the filter with pore sizes  big enough to get rid of virus you would also let out things like antibodies and other blood proteins.
 
2021-04-12 4:22:42 PM  
OK it's not size based like a standard dialysis membrane. It has some sort of adsorptive material on it that binds the virus, and other things probably as these types of things are non-specific.
 
2021-04-12 4:22:48 PM  
Well sure. If you are okay trying to live with plasma instead of blood.

/didn't read TFA
 
2021-04-12 4:27:22 PM  
Wow, that's awesome
 
2021-04-12 4:29:56 PM  

Jackal_N: That's damned amazing! I guess all of those billions of dollars we sink into DARPA are paying off a bit.


Add it to the list!
 
2021-04-12 4:36:06 PM  

Bootleg: That's cool. What does it do in terms of survivability and at what level of infection? How soon can we push this out everywhere?


The thread says a woman was near death and opted into a study. The filter attaches to a regular dialysis machine and completely removes the virus from a person's blood. The woman was in great health after a few days.
 
2021-04-12 4:37:24 PM  

IgG4: Something about that doesn't add up. Coronavirus is way too big to diffuse out of a standard dialysis cartridge. Those are meant to let out very small molecular weight waste products. If you made the filter with pore sizes  big enough to get rid of virus you would also let out things like antibodies and other blood proteins.


From the thread...

I think its The CytoSorb. It doesn't remove specifically the virus, it removes the cytokines in a cytokine storm. If that works, its a major breakthrough for any kind of sepsis

Does that make any sense?
 
Juc
2021-04-12 4:42:48 PM  
seems like when people are about to go kablooie they can plug 'em into the old blood filter and get their bodies to stop filling their lungs with shiat long enough for people to recover.
that's my read on it anyway.
 
2021-04-12 4:43:31 PM  

physt: IgG4: Something about that doesn't add up. Coronavirus is way too big to diffuse out of a standard dialysis cartridge. Those are meant to let out very small molecular weight waste products. If you made the filter with pore sizes  big enough to get rid of virus you would also let out things like antibodies and other blood proteins.

From the thread...

I think its The CytoSorb. It doesn't remove specifically the virus, it removes the cytokines in a cytokine storm. If that works, its a major breakthrough for any kind of sepsis

Does that make any sense?


If true, that is fan-freaking-tastic with ramifications way beyond Covid treatment.
 
2021-04-12 4:44:43 PM  

disaster bastard: Bootleg: That's cool. What does it do in terms of survivability and at what level of infection? How soon can we push this out everywhere?

The thread says a woman was near death and opted into a study. The filter attaches to a regular dialysis machine and completely removes the virus from a person's blood. The woman was in great health after a few days.


28 days later...
 
2021-04-12 4:48:04 PM  
Is it filled with Clorox?
 
2021-04-12 4:50:02 PM  
I saw this on 60 Minutes last night and really wonder how exactly it works.
 
2021-04-12 4:52:05 PM  

RolandTGunner: I saw this on 60 Minutes last night and really wonder how exactly it works.


Ball bearings.  It's all ball bearings these days.
 
2021-04-12 4:52:26 PM  

Jackal_N: That's damned amazing! I guess all of those billions of dollars we sink into DARPA are paying off a bit.


Yeah, but on the downside:  DARPA helped create what would become the Internet, one of the worst things to ever happen to this planet

/says the guy using the Internet
 
2021-04-12 5:00:06 PM  

Bootleg: That's cool. What does it do in terms of survivability and at what level of infection? How soon can we push this out everywhere?


100% full recovery for critically ill patients.
 
Juc
2021-04-12 5:01:41 PM  

RolandTGunner: I saw this on 60 Minutes last night and really wonder how exactly it works.


well they're broad spectrum filters that remove a bunch of stuff from blood, that you hook up to a dialysis machine.
You pass blood through the machine, it takes the junk out, and you're left with filtered blood that goes back into the body.
There's two filters that are being tested and they weren't made specifically for covid, they were made to filter out a whole shwack of pathogens. They got funding for these two filters from the success of a previous pathogen agnostic blood filter.

both those new filters apparently remove covid, and they're being checked for general treatment of sepsis (which would save a ton of people's lives if that pans out, about a quarter million deaths per year from just infections gone awry)

I sorta want to read through the research papers on this stuff but I got the feeling the data's not really open to shlubs to peruse.

anybody got good links for additional info?
 
2021-04-12 5:27:24 PM  

IgG4: OK it's not size based like a standard dialysis membrane. It has some sort of adsorptive material on it that binds the virus, and other things probably as these types of things are non-specific.


Username checks out.
 
2021-04-12 5:45:14 PM  
It's like y'all are amazed by "new" stories that are on Twitter today...that appeared in full on 60 Minutes last night.
 
2021-04-12 5:50:20 PM  

johnny_vegas: Jackal_N: That's damned amazing! I guess all of those billions of dollars we sink into DARPA are paying off a bit.

Add it to the list!


That was interesting. Thanks!
 
2021-04-12 5:54:13 PM  

xanadian: Jackal_N: That's damned amazing! I guess all of those billions of dollars we sink into DARPA are paying off a bit.

Yeah, but on the downside:  DARPA helped create what would become the Internet, one of the worst things to ever happen to this planet

/says the guy using the Internet


I know, the Internet does seem to create a bit more havoc than expected.

/Says someone else using the Internet.
 
2021-04-12 5:58:22 PM  

wejash: It's like y'all are amazed by "new" stories that are on Twitter today...that appeared in full on 60 Minutes last night.


Not many people watch broadcast networks anymore.
 
2021-04-12 6:11:41 PM  

IgG4: Something about that doesn't add up. Coronavirus is way too big to diffuse out of a standard dialysis cartridge. Those are meant to let out very small molecular weight waste products. If you made the filter with pore sizes  big enough to get rid of virus you would also let out things like antibodies and other blood proteins.


You might be able to do it with synthetic antibody molecules anchored to large plastic beads, to grab and hold the spike proteins of passing virus particles.
 
2021-04-12 6:24:54 PM  

wejash: It's like y'all are amazed by "new" stories that are on Twitter today...that appeared in full on 60 Minutes last night.


Yeah well, there's a reason for that. Most of the younger generations don't watch 60 Minutes. I have it set to record every week because I grew up watching it. I deleted this episode without even looking at the preview because the description said "the efforts of the scientific community and the military to prevent future pandemics."

/Just pulled it out of the trash to watch later.
//Already feel 10 years older.
 
2021-04-12 6:38:34 PM  

Jackal_N: wejash: It's like y'all are amazed by "new" stories that are on Twitter today...that appeared in full on 60 Minutes last night.

Yeah well, there's a reason for that. Most of the younger generations don't watch 60 Minutes. I have it set to record every week because I grew up watching it. I deleted this episode without even looking at the preview because the description said "the efforts of the scientific community and the military to prevent future pandemics."

/Just pulled it out of the trash to watch later.
//Already feel 10 years older.


Your onion belt will arrive in the mail shortly.
 
2021-04-12 6:41:31 PM  

jclaggett: Jackal_N: wejash: It's like y'all are amazed by "new" stories that are on Twitter today...that appeared in full on 60 Minutes last night.

Yeah well, there's a reason for that. Most of the younger generations don't watch 60 Minutes. I have it set to record every week because I grew up watching it. I deleted this episode without even looking at the preview because the description said "the efforts of the scientific community and the military to prevent future pandemics."

/Just pulled it out of the trash to watch later.
//Already feel 10 years older.

Your onion belt will arrive in the mail shortly.


If Andy Rooney were still around, he'd do a segment on "what's the deal with these internets cribbing our stories?"
 
2021-04-12 7:06:02 PM  

physt: IgG4: Something about that doesn't add up. Coronavirus is way too big to diffuse out of a standard dialysis cartridge. Those are meant to let out very small molecular weight waste products. If you made the filter with pore sizes  big enough to get rid of virus you would also let out things like antibodies and other blood proteins.

From the thread...

I think its The CytoSorb. It doesn't remove specifically the virus, it removes the cytokines in a cytokine storm. If that works, its a major breakthrough for any kind of sepsis

Does that make any sense?


Yes it does, but that isn't the same as "it takes the virus out" as quoted in TST (The Stupid Tweet (there is no other kind) ).  It absolutely could be a game changer for sepsis by any cause, for sure.
 
2021-04-12 7:08:09 PM  

Jackal_N: wejash: It's like y'all are amazed by "new" stories that are on Twitter today...that appeared in full on 60 Minutes last night.

Yeah well, there's a reason for that. Most of the younger generations don't watch 60 Minutes. I have it set to record every week because I grew up watching it. I deleted this episode without even looking at the preview because the description said "the efforts of the scientific community and the military to prevent future pandemics."

/Just pulled it out of the trash to watch later.
//Already feel 10 years older.


I don't watch 60 Minutes or TV at all and I'm most assuredly NOT the younger generation.
 
2021-04-12 7:17:53 PM  

IgG4: OK it's not size based like a standard dialysis membrane. It has some sort of adsorptive material on it that binds the virus, and other things probably as these types of things are non-specific.


It's a chromatography column that binds cytokines.  These will be very expensive to manufacture and use.  On the other hand they should work for anyone in septic shock which is really amazing.
 
2021-04-12 8:45:57 PM  

Northern: IgG4: OK it's not size based like a standard dialysis membrane. It has some sort of adsorptive material on it that binds the virus, and other things probably as these types of things are non-specific.

It's a chromatography column that binds cytokines.  These will be very expensive to manufacture and use.  On the other hand they should work for anyone in septic shock which is really amazing.


Seems like you might accomplish the same if you run 10 pints of compatible donor blood into the patient's right arm while draining 10 pints from the left.  Dialysis as replacement instead of filtration.
 
2021-04-12 8:49:59 PM  
The sad and gross ;art if DARPA. fark those monsters, who ouwldn't fund medicine for a milisecond of their lives, but fund only things that help sodliers go out and kill.

DARPA kept this on the shelf for how long?? How long?????

DARPA isn't medicine, it's just a killing factory. We need to get ahold of their tech. Think of all the people who died from viruses that this mahcine would have helped.
 
2021-04-12 9:07:46 PM  

Bennie Crabtree: The sad and gross ;art if DARPA. fark those monsters, who ouwldn't fund medicine for a milisecond of their lives, but fund only things that help sodliers go out and kill.

DARPA kept this on the shelf for how long?? How long?????

DARPA isn't medicine, it's just a killing factory. We need to get ahold of their tech. Think of all the people who died from viruses that this mahcine would have helped.


Dude... Put down the bong.
 
2021-04-12 9:35:25 PM  
Bennie Crabtree:

DARPA kept this on the shelf for how long?? How long?????

Until the spring of 2020, when Col Stephen Olson and others conducted a study to see if the Seraph 100 extracorporeal blood filter might help patients with severe COVID symptoms.  It did.  Results were announced in August of 2020.

I think there're some misunderstandings here.  Best I can see is The Stupid Tweet - and possibly 60 Minutes as the source - is full of shiat with regard to "filtering the virus".
 
2021-04-12 10:17:41 PM  

Northern: It's a chromatography column that binds cytokines.  These will be very expensive to manufacture and use.  On the other hand they should work for anyone in septic shock which is really amazing.


Cross your fingers it doesn't get sucked up under ITAR or patent-restricted to patients with billionaire-level net worth.
 
2021-04-12 10:23:31 PM  

Bennie Crabtree: The sad and gross ;art if DARPA. fark those monsters, who ouwldn't fund medicine for a milisecond of their lives, but fund only things that help sodliers go out and kill.

DARPA kept this on the shelf for how long?? How long?????

DARPA isn't medicine, it's just a killing factory. We need to get ahold of their tech. Think of all the people who died from viruses that this mahcine would have helped.


It's ironic this blathering screed is inflicted on everyone one via the internet
 
2021-04-12 10:30:04 PM  

physt: IgG4: Something about that doesn't add up. Coronavirus is way too big to diffuse out of a standard dialysis cartridge. Those are meant to let out very small molecular weight waste products. If you made the filter with pore sizes  big enough to get rid of virus you would also let out things like antibodies and other blood proteins.

From the thread...

I think its The CytoSorb. It doesn't remove specifically the virus, it removes the cytokines in a cytokine storm. If that works, its a major breakthrough for any kind of sepsis

Does that make any sense?


Your immune system, instead of calmly calling 911, puts a microphone in front a half stack turned to 11 and yells "RUN FOR THE HILLS".

Or you can think of it as friendly fire.

Thank Frak dot com for throwing away the link.

https://www.health.com/condition/infec​tious-diseases/coronavirus/cytokine-st​orm
 
2021-04-12 11:42:37 PM  
Yeah, but what about Rick Gingle-Gangle-Jingle?
 
2021-04-13 1:54:03 AM  
Sounds like the biofilter on a Star Trek transporter.  Cool shiat
 
2021-04-13 12:07:46 PM  

Bennie Crabtree: The sad and gross ;art if DARPA. fark those monsters, who ouwldn't fund medicine for a milisecond of their lives, but fund only things that help sodliers go out and kill.

DARPA kept this on the shelf for how long?? How long?????

DARPA isn't medicine, it's just a killing factory. We need to get ahold of their tech. Think of all the people who died from viruses that this mahcine would have helped.


Helping soldiers survive also helps non-soldiers survive.  DARPA is heavily incentivized to transition their technology outside of the DOD, and their spinoffs include things like the Internet.  They didn't "keep this on the shelf", any more than mRNA vaccines have been "kept on the shelf".  It's a new technology, but was approved for medical use in Europe two years ago, and is being rushed out in the U.S. for COVID-19 applications under emergency FDA authorization given the urgency of the pandemic.
 
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