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(NYPost)   No, constantly tripping balls is not a productivity hack that improves your psychological well being   (nypost.com) divider line
    More: Obvious, Psychedelics, dissociatives and deliriants, Psilocybin mushrooms, Placebo, Psychedelic drug, low doses of psychedelic drugs, Psilocybin, Psychedelic, new study  
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2705 clicks; posted to Main » on 03 Mar 2021 at 8:10 PM (10 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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2021-03-03 6:49:15 PM  
Yeah, it's hard to concentrate on spreadsheets when they're melting... But, it's great for your psychological wellbeing.
 
2021-03-03 7:29:42 PM  
Researchers virtually guided study participants - all of whom were already regularly microdosing - through the process of preparing themselves four week's worth of envelopes containing either a placebo gel capsule or one with a low LSD dose, each envelope bearing a QR code they logged following consumption.
At the end of the trial period, researchers found that participants reported an improvement in psychological well being across the board, whether they were taking actual acid or placebos.

Participants were allowed to use any psychedelic substance to microdose with. The microdose dose, which is the amount of substance to use as a microdose, was not defined for participants, rather they were instructed to use a microdose dose that they would use outside the study.The rationale for this direction was threefold. First, given that participants typically would source their substance from the black market, the precise microdose dose could not have been known even if instructions requested it. Second, based on community feedback, most experienced microdosers have a preferred dose that they would not have liked to change to participate in the study. Lastly, this study was not a clinical trial and therefore from a regulatory perspective not allowing for control over and/or directing about drug doses.


Fark user imageView Full Size


There is a long more wrong with the study, but I stopped reading after I skimmed a bit. They didn't power the study correctly. Of the 246 who started the study, only 159 finished. Washout period of 1 week. People were taking mushrooms and/or LSD-like substances and/or other hallucinigentic drugs. And the whole structure of the study was weird ... but I don't care anymore.Anecdotally, Microdosing LSD helps with a variety of mental health problems. But according to this study, anecdotally it does not.tldr: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.
 
2021-03-03 8:09:42 PM  
I love microdosing at work. Until the LSD wears off and I realize I'm still in the car.
 
2021-03-03 8:11:52 PM  
Bootsy Collins disagrees
 
2021-03-03 8:12:53 PM  
I tried microdosing on mushrooms. It feels like you have to sneeze but can't.
 
2021-03-03 8:14:09 PM  
i.pinimg.comView Full Size
 
2021-03-03 8:14:39 PM  
Whelp looks like we can pack up all the research being conducted into the use of psilocybin to improve psychological well being because this one article in the NY Post (lmfao) about this one study said it was all bullshiat.

Poorly designed study, poorly written article, and idiotic headline even for Fark.com.
 
2021-03-03 8:14:49 PM  
i.pinimg.comView Full Size
 
2021-03-03 8:15:22 PM  
fark the NY Post
 
2021-03-03 8:16:06 PM  
I still want to try it. For science
 
2021-03-03 8:16:32 PM  

BigLuca: Researchers virtually guided study participants - all of whom were already regularly microdosing - through the process of preparing themselves four week's worth of envelopes containing either a placebo gel capsule or one with a low LSD dose, each envelope bearing a QR code they logged following consumption.
At the end of the trial period, researchers found that participants reported an improvement in psychological well being across the board, whether they were taking actual acid or placebos.

Participants were allowed to use any psychedelic substance to microdose with. The microdose dose, which is the amount of substance to use as a microdose, was not defined for participants, rather they were instructed to use a microdose dose that they would use outside the study.The rationale for this direction was threefold. First, given that participants typically would source their substance from the black market, the precise microdose dose could not have been known even if instructions requested it. Second, based on community feedback, most experienced microdosers have a preferred dose that they would not have liked to change to participate in the study. Lastly, this study was not a clinical trial and therefore from a regulatory perspective not allowing for control over and/or directing about drug doses.


[Fark user image image 272x254]

There is a long more wrong with the study, but I stopped reading after I skimmed a bit. They didn't power the study correctly. Of the 246 who started the study, only 159 finished. Washout period of 1 week. People were taking mushrooms and/or LSD-like substances and/or other hallucinigentic drugs. And the whole structure of the study was weird ... but I don't care anymore.Anecdotally, Microdosing LSD helps with a variety of mental health problems. But according to this study, anecdotally it does not.tldr: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.


Run a lot of research studies with Schedule I substances, do you?

Might want to at least compare it to the vast majority of available literature from US groups before you jump to conclusions about the quality.
 
2021-03-03 8:17:23 PM  

BigLuca: Researchers virtually guided study participants - all of whom were already regularly microdosing - through the process of preparing themselves four week's worth of envelopes containing either a placebo gel capsule or one with a low LSD dose, each envelope bearing a QR code they logged following consumption.
At the end of the trial period, researchers found that participants reported an improvement in psychological well being across the board, whether they were taking actual acid or placebos.

Participants were allowed to use any psychedelic substance to microdose with. The microdose dose, which is the amount of substance to use as a microdose, was not defined for participants, rather they were instructed to use a microdose dose that they would use outside the study.The rationale for this direction was threefold. First, given that participants typically would source their substance from the black market, the precise microdose dose could not have been known even if instructions requested it. Second, based on community feedback, most experienced microdosers have a preferred dose that they would not have liked to change to participate in the study. Lastly, this study was not a clinical trial and therefore from a regulatory perspective not allowing for control over and/or directing about drug doses.


[Fark user image image 272x254]

There is a long more wrong with the study, but I stopped reading after I skimmed a bit. They didn't power the study correctly. Of the 246 who started the study, only 159 finished. Washout period of 1 week. People were taking mushrooms and/or LSD-like substances and/or other hallucinigentic drugs. And the whole structure of the study was weird ... but I don't care anymore.Anecdotally, Microdosing LSD helps with a variety of mental health problems. But according to this study, anecdotally it does not.tldr: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.


But it was published in eLife, which the NYPost called a scientific journal.  I don't know what more you need .
 
2021-03-03 8:17:55 PM  
Wife tried microdosing for a while. Didn't seem to have any effect. Not saying it doesn't work, others may have different experiences.
 
2021-03-03 8:18:11 PM  
The placebo effect is as strong as weak acid. See miracles at Lourdes, etc.
 
2021-03-03 8:18:44 PM  
NYPost said it which means the truth is probably that downing a 10 strip a day grants immortality.
 
2021-03-03 8:19:01 PM  
Ok, now try macrodosing.
 
2021-03-03 8:19:27 PM  
This goes a long way towards explaining California politics.
 
2021-03-03 8:21:11 PM  
Sounds like a waste of LSD
 
2021-03-03 8:22:10 PM  
Says you, stupid talking houseplant.
 
2021-03-03 8:22:41 PM  

bigdog1960: The placebo effect is as strong as weak acid. See miracles at Lourdes, etc.


True. The previously initiated my experience a number of physiological phenomena associated with certain substances simply by discussing them or thinking about ingesting them. Or so they say.
 
2021-03-03 8:22:42 PM  

BigLuca: And the whole structure of the study was weird ... but I don't care anymore.Anecdotally, Microdosing LSD helps with a variety of mental health problems. But according to this study, anecdotally it does not.tldr: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.


They say "the plural of anecdote is not data", but after reading through the study, it looks like the authors were attempting it as a proof-of-concept for gathering enough anecdotes to glean meaningful data from them. I think their idea is that most of the uncontrolled variables will average out simply through the good-faith diligence of the participants. It's an interesting concept, but whether or not they actually succeeded in gathering "meaningful data" is another matter entirely.

I would like to see a study like this repeated on a much larger scale, and on a group of participants who aren't biased about what the results will be (such as people who already microdose because they believe it helps them). Pretty hard to recruit for a large study that inherently requires breaking the law though.
 
2021-03-03 8:24:17 PM  
Microdosing =/= tripping balls
 
2021-03-03 8:24:23 PM  
 
2021-03-03 8:27:58 PM  

GranoblasticMan: Might want to at least compare it to the vast majority of available literature from US groups before you jump to conclusions about the quality.


"The report is full of numerous concessions regarding the the study's weaknesses, including that it had a small participant pool and was performed by citizens, who were not in a clinical setting."

From TFA
 
2021-03-03 8:28:05 PM  
I have a farking tiger, man, and he's wearing a saddle!
 
2021-03-03 8:34:10 PM  
Ketamine works for me. Neuroscience, fark yeah.
 
2021-03-03 8:35:44 PM  
There's not much difference between a placebo effect and a non-placebo effect functionally. Even less when you're tripping.
 
2021-03-03 8:38:32 PM  
Yeah, well you try driving from New York to Key West on rest stop coffee, smart ass.
 
2021-03-03 8:38:33 PM  

BigLuca: Researchers virtually guided study participants - all of whom were already regularly microdosing - through the process of preparing themselves four week's worth of envelopes containing either a placebo gel capsule or one with a low LSD dose, each envelope bearing a QR code they logged following consumption.
At the end of the trial period, researchers found that participants reported an improvement in psychological well being across the board, whether they were taking actual acid or placebos.

Participants were allowed to use any psychedelic substance to microdose with. The microdose dose, which is the amount of substance to use as a microdose, was not defined for participants, rather they were instructed to use a microdose dose that they would use outside the study.The rationale for this direction was threefold. First, given that participants typically would source their substance from the black market, the precise microdose dose could not have been known even if instructions requested it. Second, based on community feedback, most experienced microdosers have a preferred dose that they would not have liked to change to participate in the study. Lastly, this study was not a clinical trial and therefore from a regulatory perspective not allowing for control over and/or directing about drug doses.


[Fark user image 272x254]

There is a long more wrong with the study, but I stopped reading after I skimmed a bit. They didn't power the study correctly. Of the 246 who started the study, only 159 finished. Washout period of 1 week. People were taking mushrooms and/or LSD-like substances and/or other hallucinigentic drugs. And the whole structure of the study was weird ... but I don't care anymore.Anecdotally, Microdosing LSD helps with a variety of mental health problems. But according to this study, anecdotally it does not.tldr: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.


More like an ethnography, really. It is still informative. Taking drugs at work is a waste of drugs.
 
2021-03-03 8:40:12 PM  

wax_on: Wife tried microdosing for a while. Didn't seem to have any effect. Not saying it doesn't work, others may have different experiences.


the wife and i tried it for about six months. we really didn't notice anything. one day before my morning run, though, i took a *little bit* more than usual. still wasn't tripping or anything, but i did feel the need to stop at a point on the trail that had a bunch of young sycamore trees and admire their beauty. the usual bong hits and the tiny bit of mushrooms along with the runner's high was awesome that day.
 
2021-03-03 8:40:39 PM  
But it could be
 
2021-03-03 8:40:48 PM  
thumbs.gfycat.comView Full Size
 
2021-03-03 8:43:15 PM  

Al Roker's Forecast: I love microdosing at work. Until the LSD wears off and I realize I'm still in the car.


Just last night I raised my hands to begin my prayers...and realized I was in bed dreaming.
 
2021-03-03 8:45:24 PM  

wax_on: Wife tried microdosing for a while. Didn't seem to have any effect. Not saying it doesn't work, others may have different experiences.


To what objective, if I may ask?
 
2021-03-03 8:46:36 PM  

GranoblasticMan: BigLuca: Researchers virtually guided study participants - all of whom were already regularly microdosing - through the process of preparing themselves four week's worth of envelopes containing either a placebo gel capsule or one with a low LSD dose, each envelope bearing a QR code they logged following consumption.
At the end of the trial period, researchers found that participants reported an improvement in psychological well being across the board, whether they were taking actual acid or placebos.

Participants were allowed to use any psychedelic substance to microdose with. The microdose dose, which is the amount of substance to use as a microdose, was not defined for participants, rather they were instructed to use a microdose dose that they would use outside the study.The rationale for this direction was threefold. First, given that participants typically would source their substance from the black market, the precise microdose dose could not have been known even if instructions requested it. Second, based on community feedback, most experienced microdosers have a preferred dose that they would not have liked to change to participate in the study. Lastly, this study was not a clinical trial and therefore from a regulatory perspective not allowing for control over and/or directing about drug doses.


[Fark user image image 272x254]

There is a long more wrong with the study, but I stopped reading after I skimmed a bit. They didn't power the study correctly. Of the 246 who started the study, only 159 finished. Washout period of 1 week. People were taking mushrooms and/or LSD-like substances and/or other hallucinigentic drugs. And the whole structure of the study was weird ... but I don't care anymore.Anecdotally, Microdosing LSD helps with a variety of mental health problems. But according to this study, anecdotally it does not.tldr: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.

Run a lot of research studies with Schedule I substances, do you?

Might want to at least compare it to the vast majority of available literature from US groups before you jump to conclusions about the quality.


https://youtu.be/42QuXLucH3Q
Is probably more home boy's level.  Then he can move up to reading John Ioannidis.
 
2021-03-03 8:49:38 PM  
I would recommend that everybody try a (benign) hallucinogen at least once in their lives. It may change the way you look at things going forward.
 
2021-03-03 8:50:26 PM  

BigLuca: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.


Says the guy who can't bother to find the open access manuscript.

eLife is a perfectly fine journal whose peer review is unusually open.
 
2021-03-03 8:51:14 PM  
Now you tell me.
 
2021-03-03 8:54:07 PM  

culebra: Whelp looks like we can pack up all the research being conducted into the use of psilocybin to improve psychological well being because this one article in the NY Post (lmfao) about this one study said it was all bullshiat.

Poorly designed study, poorly written article, and idiotic headline even for Fark.com.


Not only that but I'm pretty sure there results showed dramatic improvements for every single microdoser. So I mean... even if it's not what they think, it apparently ain't that bad either.
 
2021-03-03 8:56:51 PM  
Look I'm not a scientist but if you mix it with painkillers, weed, coke, and booze it will help
 
2021-03-03 8:58:41 PM  
Whatever. I'm still going to put a little bit of this mystery oil on my butthole.
 
2021-03-03 9:00:44 PM  

wantingout: Microdosing =/= tripping balls


People who microdose might as well drink O'douls "non alcoholic" "beer". It has alcohol, just not enough to get you drunk.

Same bs concept.
 
2021-03-03 9:00:53 PM  
I've found microdosing with mushrooms helpful when I'm very depressed.

I find microdosing with LSD to be annoying and pointless, I much prefer megadosing whenever I have some spare time.
 
2021-03-03 9:03:20 PM  

Wine Sipping Elitist: wantingout: Microdosing =/= tripping balls

People who microdose might as well drink O'douls "non alcoholic" "beer". It has alcohol, just not enough to get you drunk.

Same bs concept.


Because as we all know, all drugs are exactly the same.
 
2021-03-03 9:03:47 PM  
I've found that microdosing with Scotch throughout the day really umprobvs my peohductity adn psysvghcologlac welln been.
 
2021-03-03 9:04:17 PM  

BigLuca: Researchers virtually guided study participants - all of whom were already regularly microdosing - through the process of preparing themselves four week's worth of envelopes containing either a placebo gel capsule or one with a low LSD dose, each envelope bearing a QR code they logged following consumption.
At the end of the trial period, researchers found that participants reported an improvement in psychological well being across the board, whether they were taking actual acid or placebos.

Participants were allowed to use any psychedelic substance to microdose with. The microdose dose, which is the amount of substance to use as a microdose, was not defined for participants, rather they were instructed to use a microdose dose that they would use outside the study.The rationale for this direction was threefold. First, given that participants typically would source their substance from the black market, the precise microdose dose could not have been known even if instructions requested it. Second, based on community feedback, most experienced microdosers have a preferred dose that they would not have liked to change to participate in the study. Lastly, this study was not a clinical trial and therefore from a regulatory perspective not allowing for control over and/or directing about drug doses.


[Fark user image 272x254]

There is a long more wrong with the study, but I stopped reading after I skimmed a bit. They didn't power the study correctly. Of the 246 who started the study, only 159 finished. Washout period of 1 week. People were taking mushrooms and/or LSD-like substances and/or other hallucinigentic drugs. And the whole structure of the study was weird ... but I don't care anymore.Anecdotally, Microdosing LSD helps with a variety of mental health problems. But according to this study, anecdotally it does not.tldr: This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.


Goddamn I love it when someone absolutely crushes it two posts into the thread. Hit the lights.
 
2021-03-03 9:05:07 PM  
My purple platypus friend here in the copilot's chair of my cola-powered spaceship says you're a liar.

He also seems to think I'm a woman and into him, but that's not what this is about.
 
2021-03-03 9:05:22 PM  
Doesn't look very scientific to me.
 
2021-03-03 9:07:55 PM  
I'm pissed that this was about microdosing. I thought it was going to be about some kind of flip. I used to drop acid on Saturday, shroom on monday, acid on wednesday, and shrooms again thursday. Not EVERY week but some weeks. College was great.

I genuinely believe if I was still doing that from time to time, I'd probably be relentlessly productive and positive. I'm just too old to easily obtain drugs. And I have cop hair.
 
2021-03-03 9:09:22 PM  
BigLuca:

This 'study' was an attention grab to get published in mainstream media. No respectable journal would even read past the abstract.

But, a newspaper as reputable as the NY Post has only the highest journalistic ethics. Why would they lie to me?
 
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