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(CTV News)   This seems like big news   (montreal.ctvnews.ca) divider line
    More: News, Hospital, Patient, Pharmacology, Colchicine, Quebec, Illness, ColCorona study, team of researchers  
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16816 clicks; posted to Main » on 24 Jan 2021 at 8:17 PM (5 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



220 Comments     (+0 »)
 
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2021-01-24 7:26:16 PM  
Reducing deaths by 44%.

Okay, then.

I really hope this is true. Seems like a solid study, though: double blind and over 4,000 participants.
 
2021-01-24 7:31:57 PM  
If it would prevent Covid-19 would be cool. But this is definitely cool for helping people that already have Covid-19.
 
2021-01-24 7:35:38 PM  
This seems like big news


This seems a lot like hydroxychloroquine.
 
2021-01-24 7:39:29 PM  

Badmoodman: This seems like big news


This seems a lot like hydroxychloroquine.


User name checks out ;-)
anyway I don't think it is. This was a high quality study of a significant number of patients and double blind. So, another study is needed to confirm. But it is a very good result.

If I tested positive tomorrow I'd be taking it.
 
2021-01-24 7:40:20 PM  

WTFDYW: If it would prevent Covid-19 would be cool. But this is definitely cool for helping people that already have Covid-19.


The vaccine is for prevention.
 
2021-01-24 7:40:47 PM  
I'll just stick with bleach, thanks anyway.
 
2021-01-24 7:40:54 PM  

Sepia apama: Reducing deaths by 44%.

Okay, then.

I really hope this is true. Seems like a solid study, though: double blind and over 4,000 participants.


Reduces the need for mechanical ventilation by 50%, thereby lessening the burden on the hospital system.
Drug used to treat gout for hundreds of years? Let's get rolling on the peer review.
 
2021-01-24 7:43:06 PM  
(looks at the picture)

Why are they popping flexeril out of a M&M Mini's tube?
 
jbc [TotalFark]
2021-01-24 7:45:25 PM  
I don't know that people are going to want a pill covered in gravy and cheese curds.
 
2021-01-24 7:47:54 PM  
Hell yeah. Those hospital reductions are nothing to scoff at. The fact that it's a prevalent drug is huge, as well. I feel like there has to be a catch.

With this news, the current vaccines, and the latest news from Johnson & Johnson... I might go see a movie in a theatre this spring already.
 
2021-01-24 7:51:30 PM  
confirmed by a nasopharyngeal test (PCR).

The PCR is NOT a reliable way to confirm if someone has COVID. It's only a starting point, even the WHO has said so. A real COVID diagnosis requires real clinical work.
 
2021-01-24 7:51:54 PM  
 
2021-01-24 7:54:43 PM  

dj_bigbird: confirmed by a nasopharyngeal test (PCR).

The PCR is NOT a reliable way to confirm if someone has COVID. It's only a starting point, even the WHO has said so. A real COVID diagnosis requires real clinical work.


The false positive rate on the pcr test is close to zero.

You really are wrong about just about everything.
 
2021-01-24 7:56:37 PM  

Cake Hunter: dj_bigbird: confirmed by a nasopharyngeal test (PCR).

The PCR is NOT a reliable way to confirm if someone has COVID. It's only a starting point, even the WHO has said so. A real COVID diagnosis requires real clinical work.

The false positive rate on the pcr test is close to zero.

You really are wrong about just about everything.


I'll add that a negative covid test is not a reliable way to say that you don't have it.

But you're still incredibly wrong.
 
2021-01-24 7:58:51 PM  
Colchicine is a seriously strong drug.

Works great for gout though.
 
2021-01-24 7:59:09 PM  
I really hope this pans out.
 
2021-01-24 7:59:18 PM  
If it works in canada, it will take the FDA plenty of time to approve it.
Like Avastin.

It is almost as if they have to get some finances in order to approve a working drug in America
 
2021-01-24 8:05:58 PM  

SoupGuru: Hell yeah. Those hospital reductions are nothing to scoff at. The fact that it's a prevalent drug is huge, as well. I feel like there has to be a catch.

With this news, the current vaccines, and the latest news from Johnson & Johnson... I might go see a movie in a theatre this spring already.


A 30-day supply is $33.54 at Walgreen's and $55 at CVS. We'll see what it is tomorrow.
 
2021-01-24 8:07:13 PM  
Of course, in the US, this isn't a FDA approved use so even if your doctor is willing to prescribe it your insurance almost certainly won't cover it.
 
2021-01-24 8:09:15 PM  
I can't believe it's not hydroxychloroquine. Shocked. I was so sure. As sure as I am that paste tastes delicious.
 
2021-01-24 8:14:46 PM  
I'll note that this study (even though it was done in Canada) was partially funded by US tax dollars (NIH).

Here's an earlier paper (yes, colchicine has been looked at as a potential treatment for a while) explaining some of the theory behind it. Looks like in addition to the anti-inflammatory properties, there's also some disruption of the polymer-building mechanisms that SARS-CoV-2 needs to replicate efficiently.

https://www.ncbi.nlm.nih.gov/pmc/arti​c​les/PMC7367785/
 
2021-01-24 8:19:31 PM  
So I guess Biden has part ownership of THAT company...

/ yes I'm joking
 
2021-01-24 8:20:11 PM  
Fark user imageView Full Size
 
2021-01-24 8:20:39 PM  

Joe USer: Colchicine is a seriously strong drug.

Works great for gout though.


Yea, like hydroxychloroquine or dexamethasone, colchicine isn't a drug you should take just willy nilly.
 
2021-01-24 8:22:15 PM  
I'm hoping that after my second shot the Moderna vaccine will work better.
 
2021-01-24 8:24:47 PM  

Ker_Thwap: I'll just stick with bleach, thanks anyway.


i.imgur.comView Full Size
 
2021-01-24 8:26:40 PM  
Nice, now find something to help long haulers get back into the swing of things.
 
2021-01-24 8:28:55 PM  
Side effects include intense cravings for poutine, maple syrup, and a shiatty French accent.
 
2021-01-24 8:29:08 PM  
You mean to say that Quebec has actually contributed something positive to mankind other than Celine Dion?
 
2021-01-24 8:29:26 PM  

SoupGuru: Hell yeah. Those hospital reductions are nothing to scoff at. The fact that it's a prevalent drug is huge, as well. I feel like there has to be a catch.

With this news, the current vaccines, and the latest news from Johnson & Johnson... I might go see a movie in a theatre this spring already.


I mean according to Covid tracking project around 110k in US hospitals now so that would be a reduction of about 27500 needing hospitalization. That is huge.
 
2021-01-24 8:29:49 PM  
Colchichine is also used to cause marijuana to poliploid, i.e., instead of division of one cell into two one cell divides into four - it was recommended in a book I read 50 years ago to make average home grown weed really good home grown weed.  Also used the horticulturists to make flowers mo' better.
 
2021-01-24 8:30:05 PM  
Colchicine is a helluva drug *Rick James*. But yeah it's basically just a very powerful anti-inflammatory like dexamethasone which just prevents your immune system from going nuts and causing friendly fire organ damage.
upload.wikimedia.orgView Full Size
 
2021-01-24 8:30:55 PM  
Holy crap!
 
2021-01-24 8:32:01 PM  
They are just figuring out to use colchicine??? Did they not watch every season of HOUSE???
 
2021-01-24 8:32:15 PM  
But I was told that socialist countries never develop new drugs because capitalism is best.
 
2021-01-24 8:32:47 PM  
Does it affect libido? I need less libido ever since Biden won
 
2021-01-24 8:33:09 PM  

fragMasterFlash: Nice, now find something to help long haulers get back into the swing of things.


If there's an inflammatory component to the long-term symptomatology, it seems like this might actually help.
 
2021-01-24 8:34:21 PM  

TomFooolery: Of course, in the US, this isn't a FDA approved use so even if your doctor is willing to prescribe it your insurance almost certainly won't cover it.


50% reduction in mechanical ventilation is more than enough for them to approve it.  Actually insurance companies cover off label uses alot.  I take an expensive immune suppressant off label and my insurance company has no problem covering it.
 
2021-01-24 8:34:22 PM  
Just don't take Skyrizzi or go see Alice while taking Cyalis and all will be good.(ask your doctor)
 
2021-01-24 8:35:26 PM  

enry: WTFDYW: If it would prevent Covid-19 would be cool. But this is definitely cool for helping people that already have Covid-19.

The vaccine is for prevention.


I know that. I guess I didn't spell it out well enough for you.
 
2021-01-24 8:35:31 PM  
But, will Bill Gates mind control chip counter act its effects?
 
2021-01-24 8:35:36 PM  
I took it for gout many years ago. Works great for that. In researching it, however, I read that it is essentially a poison, so proper dosing is pretty damned important. Here's hoping the bleach drinking set doesn't start gobbling handfuls of this stuff. Although... no, they still shouldn't
 
2021-01-24 8:36:45 PM  
That's great news!
 
2021-01-24 8:36:53 PM  

Heraclitus: But I was told that socialist countries never develop new drugs because capitalism is best.


This isn't a new drug.  It has been around for decades.
 
2021-01-24 8:37:24 PM  
To think, the doctor who said this won the Super Bowl last season now this.  That guy is great no matter what he does
 
2021-01-24 8:37:47 PM  
Fark user imageView Full Size

 
2021-01-24 8:38:45 PM  
Well, it is good to have in the utility belt if it has some benefit but colchicine jas some SERIOUS side effects and interactions so it isn't the top option for everyone unless you have a very lousy prognosis, I would think.
 
2021-01-24 8:39:38 PM  

Badmoodman: This seems like big news


This seems a lot like hydroxychloroquine.


Yeah except for the properly designed study which shows it's effective and dramatically reduces mortality.
 
2021-01-24 8:40:49 PM  

jbc: I don't know that people are going to want a pill covered in gravy and cheese curds.


Dunno - seems like a good way to GET people to take medication to me.
 
2021-01-24 8:41:07 PM  

Heraclitus: But I was told that socialist countries never develop new drugs because capitalism is best.


Canada isn't a socialist nation...
 
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