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(CNBC)   When faced with a choice of vaccines, choose Moderna Vaccine - because the only other thing 94% effective and stable at 36 to 46° F is your dog on a walk in December   (cnbc.com) divider line
    More: Cool, Vaccine, coronavirus vaccine, Vaccination, first doses of Moderna, public health officials, vaccine race, Moderna's results, Moderna  
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1689 clicks; posted to Main » on 30 Nov 2020 at 9:48 AM (19 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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2020-11-30 12:13:35 PM  

bronskrat: The one that doesn't prevent transmission? Although do any of them?


The one which hasn't yet been proven to prevent transmission. It's much harder to test for that, and I don't know if any of the clinical trials are even trying to measure that directly. However if a vaccine can prevent you from experiencing even mild symptoms, it's probably stopping the infection early enough that the patients won't be shedding significant amounts of viral particles.

So far the mRNA vaccines (Moderna and Pfizer) are looking really good. The Oxford one gets a passing grade but needs a follow-up trial to see if they can improve its efficacy by using a half dose for the first injection (e.g. to make sure it wasn't a statistical artifact due to the demographics of that subset).
 
2020-11-30 12:15:36 PM  

tuxq: Forget the vaccine, we need some medication that's going to ease the mental illness the pandemic/lockdown has created. I would like to suggest the federal legalization of marijuana.

/although I'd like a vaccine, too.


Yeah, but isn't it a breathing problem thing anyway?
So if you get huffers lung and die 20 years later, that's gonna suck too.

What you REALLY want is shrooms and LSD.
IANAS, but I don't think anyone did anything aside from falling asleep in a walk-in cooler on that stuff.
 
2020-11-30 12:26:40 PM  

WillofJ2: 11 out of 15,000 that were vaccinated got covid

185 out of 15,000 unvaccinated got covid

So only 1 percentish of unvaccinated people caught covid and the vaccine is listed as 94.1% effective?   Just relative to the tiny amounts of people that became sick?


Strictly speaking, it doesn't matter whether few or many unvaccinated got COVID-19, it matters what proportion of them got COVID-19 relative to the vaccinated treatment group: you can still estimate a high efficacy if many fewer vaccinated got it than unvaccinated.

However, the small numbers of people who got COVID means that the estimates of efficacy (whether high or low) are more uncertain.  Here's a quick-and-dirty estimate of the uncertainty (Bayesian binomial model with uniform priors; adapted from Pfizer example here):

Fark user imageView Full Size
 
2020-11-30 1:54:57 PM  

Karma Chameleon: tuxq: Forget the vaccine, we need some medication that's going to ease the mental illness the pandemic/lockdown has created. I would like to suggest the federal legalization of marijuana.

/although I'd like a vaccine, too.

If it makes you feel any better I live somewhere it's legal and it doesnt help with uneasiness. If you want to get high that's cool, so do I. But it doesnt make dealing with uncertainty any more appealing.


What you need is hemp. Lots of CBD, barely any THC. It will make you give a fark about absolutely nothing. Works for me.
 
2020-11-30 2:16:00 PM  
I suspect most people will not have the option to choose which vaccine they can get.  It's more likely to be a "get it" or "don't get it" choice.
 
2020-11-30 2:19:42 PM  

1funguy: tuxq: Forget the vaccine, we need some medication that's going to ease the mental illness the pandemic/lockdown has created. I would like to suggest the federal legalization of marijuana.

/although I'd like a vaccine, too.

Yeah, but isn't it a breathing problem thing anyway?
So if you get huffers lung and die 20 years later, that's gonna suck too.

What you REALLY want is shrooms and LSD.
IANAS, but I don't think anyone did anything aside from falling asleep in a walk-in cooler on that stuff.


Alright, definitely don't smoke it... vape it in something like a Volcano. But for the most part, it's to pass time while bored af at home.
 
2020-11-30 2:30:32 PM  
 
2020-11-30 2:56:33 PM  
Well they'd better hurry!!!

With 100 million Americans already immune they may not need the vaccine soon!
 
2020-11-30 3:28:40 PM  

tuxq: 1funguy: tuxq: Forget the vaccine, we need some medication that's going to ease the mental illness the pandemic/lockdown has created. I would like to suggest the federal legalization of marijuana.

/although I'd like a vaccine, too.

Yeah, but isn't it a breathing problem thing anyway?
So if you get huffers lung and die 20 years later, that's gonna suck too.

What you REALLY want is shrooms and LSD.
IANAS, but I don't think anyone did anything aside from falling asleep in a walk-in cooler on that stuff.

Alright, definitely don't smoke it... vape it in something like a Volcano. But for the most part, it's to pass time while bored af at home.


See? Dinosaur here...
We had to set everything on fire when I was a kid...hash, pot, etc.

The headliner of my first car looked like a winning card at a turkey shoot...
 
2020-11-30 6:24:30 PM  
I'll take the first one I can get when it's finally available to my class.  (Non-medical, non-first responder, non-essential, non-geriatric, non-underlying conditions, etc.)  Unless it's got a big list of problems by the time it's available to me.  It's not like I'm going to say, "Oh...yeah...no.  I'm not really a Pfizer kind of person.  Pass."
 
2020-11-30 7:20:26 PM  
Look, it's almost impossible to demonstrate that a vaccine will prevent "infection" and thereby communicability. Any person vaccinated can still be "innoculated" with the virus, and it is quite possible they can develop an "infection" to the extent that they may be communicable. The bottom line is that it is very promising that these vaccines will infer enough immunization to drop the Reff of this virus well below 1.0.
 
2020-11-30 9:37:17 PM  

bronskrat: The one that doesn't prevent transmission? Although do any of them?


It sounds like he's being cautiously scientific. "We don't have evidence" means just that: We don't have evidence. Can you even imagine how difficult it would be to determine with scientific rigor if people who don't get sick do spread the illness?
 
2020-11-30 9:37:49 PM  
Hot damn!

ZAZ: Like most people I will choose the vaccine that is available at my health care provider or pharmacy.  Beggars can't be choosers.


This, this, a thousand times THIS.
 
2020-12-01 1:58:22 AM  
Lawl.  The only thing Moderna has ever shipped is hype.  Sounds legit though.
 
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