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(BBC-US)   The Oxford vaccine shows at least 70% effectiveness, joining the other main contenders Moderna, Pfizer, and the strippers   (bbc.com) divider line
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1095 clicks; posted to Main » on 23 Nov 2020 at 8:33 PM (9 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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2020-11-23 6:37:14 PM  
70%?  Slackers.
 
2020-11-23 7:29:12 PM  
So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.
 
2020-11-23 7:34:06 PM  
Will it compel the vaccinated to add extra commas to lists?
 
jph
2020-11-23 8:34:35 PM  

AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.


This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.
 
2020-11-23 8:36:28 PM  
Who really cares about the Oxford Comma? Nobody but I, a grammarian and an educated person.
 
2020-11-23 8:37:01 PM  
I'll just take all of them. That's like 287% effective or something?
 
2020-11-23 8:38:23 PM  
70%? Better than Sex Panther.

Fark user imageView Full Size
 
jph
2020-11-23 8:39:29 PM  

Eravior: I'll just take all of them. That's like 287% effective or something?


This is something I'd love to find out about. Pfizer and Moderna's vaccines use different techniques, but the Oxford/AstraZeneca vaccine uses Different Science™, so perhaps the ultimate answer will be some sort of cocktail.
 
2020-11-23 8:40:41 PM  

jph: AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.

This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.


Most importantly they say they can make enough for 2B people by the end of 2021. That means we're up to 50% of the world with a 90+% efficiency vaccine in 13 months. Let's hope the rest of the major trials are as successful as we can hit nearly 100%.
 
2020-11-23 8:42:45 PM  

jph: Eravior: I'll just take all of them. That's like 287% effective or something?

This is something I'd love to find out about. Pfizer and Moderna's vaccines use different techniques, but the Oxford/AstraZeneca vaccine uses Different Science™, so perhaps the ultimate answer will be some sort of cocktail.


64.media.tumblr.comView Full Size
 
2020-11-23 8:43:07 PM  
The Oxford effectiveness gap. The capitalarchy strikes again
 
2020-11-23 8:43:32 PM  

jph: Eravior: I'll just take all of them. That's like 287% effective or something?

This is something I'd love to find out about. Pfizer and Moderna's vaccines use different techniques, but the Oxford/AstraZeneca vaccine uses Different Science™, so perhaps the ultimate answer will be some sort of cocktail.


They all use a means to produce the spoke protein for the immune system to identify, so it's unlikely a combination would be any more effective than a booster of the one you originally took, and assuming you didn't have any side effects from the first one you'd likely be exposing yourself to more risk than you mitigated.
 
2020-11-23 8:43:40 PM  

robodog: jph: AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.

This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.

Most importantly they say they can make enough for 2B people by the end of 2021.


2B or not 2B, that is the question.
 
2020-11-23 8:43:45 PM  

robodog: jph: AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.

This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.

Most importantly they say they can make enough for 2B people by the end of 2021. That means we're up to 50% of the world with a 90+% efficiency vaccine in 13 months. Let's hope the rest of the major trials are as successful as we can hit nearly 100%.


They say?
 
2020-11-23 8:48:57 PM  
Keep your vaccine. I'll just be snorting Lysol up my nostrils and praying to Jesus Christ to save me from the 'rona.
 
2020-11-23 8:49:33 PM  
I'll bet the fine print includes a proviso that it is not to be distributed to any location named Cambridge.
 
2020-11-23 8:51:18 PM  

jph: Eravior: I'll just take all of them. That's like 287% effective or something?

This is something I'd love to find out about. Pfizer and Moderna's vaccines use different techniques, but the Oxford/AstraZeneca vaccine uses Different Science™, so perhaps the ultimate answer will be some sort of cocktail.


So vaccines follow Jager rules?  Best served cold or in a cocktail. Would have been better to not need it, but you're glad it's there when you're in a bind.
 
2020-11-23 8:51:50 PM  
Between this, Pfyzer and Moderna on top of a couple of other things today, the almost immobilizing anxiety I have had all year is beginning to subside somewhat. Perhaps I'll sleep better tonight.
 
2020-11-23 8:54:26 PM  

WTFDYW: Between this, Pfyzer and Moderna on top of a couple of other things today, the almost immobilizing anxiety I have had all year is beginning to subside somewhat. Perhaps I'll sleep better tonight.


Don't worry. Drew knows where you sleep.
 
2020-11-23 8:58:21 PM  
All assuming it hasn't mutated yet..

There are two big reasons we can't eliminate the flu. One of them is the mutation issue.

The other is that not enough people would get the shot.

Welcome to getting flu and COVID each year.
 
2020-11-23 8:58:57 PM  
Apparently it increases to 90% if you start with a half dose and then have a full dose later on as a booster. Also it doesn't need to be kept at as low a temperature as the other two successful candidates. This is really, really good news. Three vaccines in less than a year.
 
2020-11-23 9:00:20 PM  
The more the better then
 
2020-11-23 9:00:28 PM  

akede: All assuming it hasn't mutated yet..

There are two big reasons we can't eliminate the flu. One of them is the mutation issue.

The other is that not enough people would get the shot.

Welcome to getting flu and COVID each year.


Fark and pessimism. Aren't there drugs for this?
 
2020-11-23 9:02:06 PM  
The difference between them and pfizer/moderna? They are british. They are less likely to lie their asses off for profit.

I bet the pfizer/moderna vaccine is also around 70% effective, not 90%.
 
2020-11-23 9:03:46 PM  
JnJ is still developing another version, also with concurrent production
 
2020-11-23 9:04:03 PM  

AliceBToklasLives: Will it compel the vaccinated to add extra commas to lists?


Nah. But it will allow some to accept loses and disassociate for the greater good.
i.imgur.comView Full Size


/Sad for the loss and the loss to come
//Hey, where are all the dinosaurs?
///Childhoods End.
 
2020-11-23 9:04:32 PM  
i took two astra ones at 90% to take it to 99% effective....it feels like its getting warmer and the room is spinning
 
2020-11-23 9:05:08 PM  
There is so much pressure and money involved with all of these companies and scientists I would take any figure with a teaspoon of salt. There is not even a consensus on what effectiveness even means other than generating some degree of resistance and how you translate that into numerics
/no I am not an anti-vaxxer just skeptical of everything...I'll take them all right now if given the offer
//I think Moderna has the best one just for transportation purposes
 
2020-11-23 9:05:50 PM  
If I take one of each can I get to 99.9%?
 
jph
2020-11-23 9:05:51 PM  

lolmao500: The difference between them and pfizer/moderna? They are british. They are less likely to lie their asses off for profit.

I bet the pfizer/moderna vaccine is also around 70% effective, not 90%.


The Pfizer vaccine is co-developed with BioNTech. As for 'lying their asses off,' I seriously doubt any company would want to get caught lying about this. The consequences would be immense.

For a good idea of what 'immense consequences' look like, go read the book (not the movie) World War Z.
 
2020-11-23 9:05:54 PM  

Snarfangel: robodog: jph: AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.

This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.

Most importantly they say they can make enough for 2B people by the end of 2021.

2B or not 2B, that is the question.


2B?
Fark user imageView Full Size
 
2020-11-23 9:06:14 PM  

jph: AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.

This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.


We can't feed everyone with shelf stable food. How can anyone think we have solved even this logistical problem? So many are so bad at maths. Enjoy your leech therapy you farking vampires.
 
2020-11-23 9:08:52 PM  

jph: AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.

This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.


We are as ignorant as we have always been. Nothing has changed in 6000 years.

It's sickening. Oh look, cute doggies! I want to sp nd money on them while I ignore the crippled woman on the corner that I can't even b bothered to look at in my personal moving coffin that burns dead dinosaurs

/Fu Fark ai
 
2020-11-23 9:10:08 PM  

berylman: There is so much pressure and money involved with all of these companies and scientists I would take any figure with a teaspoon of salt. There is not even a consensus on what effectiveness even means other than generating some degree of resistance and how you translate that into numerics
/no I am not an anti-vaxxer just skeptical of everything...I'll take them all right now if given the offer
//I think Moderna has the best one just for transportation purposes


Better than taken with a grain of salt, right?
 
2020-11-23 9:11:40 PM  

StoPPeRmobile: jph: AlgaeRancher: So if you keep it really cold does it work better?

Just kidding the article says they think they can hit 90 percent by modifying the two doses.

This is exactly it - efficacy is actually 90%. What's more, the storage properties are superior. While it might not be 95% (unlike the Pfizer and Moderna vaccines), this one may work better for the undeveloped world without a cold transport infrastructure.

We are as ignorant as we have always been. Nothing has changed in 6000 years.

It's sickening. Oh look, cute doggies! I want to sp nd money on them while I ignore the crippled woman on the corner that I can't even b bothered to look at in my personal moving coffin that burns dead dinosaurs

/Fu Fark ai


Somebody needs a hug
 
2020-11-23 9:12:07 PM  

Schlubbe: JnJ is still developing another version, also with concurrent production


Yeah, I'm less enthused with the J&J/Janssen vaccine due to it using a common human virus as the spike carrier, but it's the most stable and it's being tested as a single dose, so as long as it's reasonably effective it will have a use case in countries with very poor medical supply chain facilities. I just wish they had applied their tech to a primate or pig virus to lower the chance of it having reduced reaction from the immune system.
 
2020-11-23 9:14:19 PM  
Status of Scumbag Vaccine currently unclear.


i.ytimg.comView Full Size

 
2020-11-23 9:18:26 PM  

akede: All assuming it hasn't mutated yet..

There are two big reasons we can't eliminate the flu. One of them is the mutation issue.

The other is that not enough people would get the shot.

Welcome to getting flu and COVID each year.


This coronavirus has a proofreading mechanism that suppresses most mutations when it's being copied.  And it's a single strand, versus flu which has seven (for the relatively uncommon influenza C) or eight different strands; within a genus, flu viruses can pretty easily swap strands with each other, leading to much larger scale mutations.

My only concerns about these were (a) how effective would they be, and (b) were the side effects going to be terrible.  The answers so far are "very" and "no", so get in a (socially distanced) line for your shots!
 
2020-11-23 9:24:38 PM  

Dork Gently: .

My only concerns about these were (a) how effective would they be, and (b) were the side effects going to be terrible.  The answers so far are "very" and "no", so get in a (socially distanced) line for your shots!


Well it sounds like doctors involved with the study are suggesting that a warning about side effects should be posted with the vaccine.  Apparently some people are experiencing pretty harsh migraines, body aches, and chills for about 24 hours, but then it recedes.  Since people need to take multiple doses, doctors are worried that people will skip on the second dose because of the severity of the side effects on the first dose
 
2020-11-23 9:28:54 PM  
There's gonna be a black market for these vaccines, right? By mid-March, you'll be able to get one out of the back of the van down by the river. $50 cash, no questions asked. Don't ask for a receipt.
 
2020-11-23 9:29:24 PM  

lolmao500: The difference between them and pfizer/moderna? They are british. They are less likely to lie their asses off for profit.

I bet the pfizer/moderna vaccine is also around 70% effective, not 90%.


British don't lie?   Don't say that around an Irishman.   This vaccine is made through Astrazeneca, a very very large multinational corporation listed on multiple stock exchanges, so I am certain they care very much about profiting from this.
 
2020-11-23 9:30:34 PM  

StoPPeRmobile: AliceBToklasLives: Will it compel the vaccinated to add extra commas to lists?

Nah. But it will allow some to accept loses and disassociate for the greater good.

Fark user imageView Full Size



Fark user imageView Full Size
 
2020-11-23 9:32:03 PM  
I'm just planning on hanging out in the blanket fort clutching my big monkeywrench while I wait to see if the first batch of people vaccinated turn into robot werewolves.
 
2020-11-23 9:34:11 PM  

bhcompy: Dork Gently: .

My only concerns about these were (a) how effective would they be, and (b) were the side effects going to be terrible.  The answers so far are "very" and "no", so get in a (socially distanced) line for your shots!

Well it sounds like doctors involved with the study are suggesting that a warning about side effects should be posted with the vaccine.  Apparently some people are experiencing pretty harsh migraines, body aches, and chills for about 24 hours, but then it recedes.  Since people need to take multiple doses, doctors are worried that people will skip on the second dose because of the severity of the side effects on the first dose


There is no question that the side effects for this vaccine are worse than for the Eli Lilly and Regeneron vaccines, but if immunity lasts for years, they're probably acceptable.  It depends on their prevalence.  Notices about side effects are often about setting expectations and letting people know they are not having a medical emergency, not about warning people away from the vaccine.
 
2020-11-23 9:36:05 PM  

ChrisDe: There's gonna be a black market for these vaccines, right? By mid-March, you'll be able to get one out of the back of the van down by the river. $50 cash, no questions asked. Don't ask for a receipt.


Given the cold chain requirements of every one of the effective candidates so far you'd have to be a fool to buy something on the black market (that's ignoring the huge chance for fraud of course).
 
2020-11-23 9:38:01 PM  

Weatherkiss: Keep your vaccine. I'll just be snorting Lysol up my nostrils and praying to Jesus Christ to save me from the 'rona.


Yeah! Let's just keep the populace wearing masks in public forever. Only a monster would not accept the risk that some might cause great harm to many for the personal feeling of security of all obscuring their identity in public.

Besides, we have eradicated all of the enemies that this empire has aquired through our great acceptance policy of agreeable acceptance of those that, I don't think I can say the politically acceptable rationale of this but I have been assured by a small portion of the population that if I do this I am not a hater. The entire planet wants nothing but unicorn farts and puppy smiles for all of us that choos to live here and we should shame all that do not accept the covering of their identity.

Geez people! We are not individuals with choices, we are but faceless workers, put on this planet, to serve our betters. Get the eff over yourselves, cover your ugly face, smell your breath constantly, and serve our masters. It can't be any more simple than that. You do not have a choice.

I am sick and tired that so-called people thinking that they have a choice. You have no choice besides purchasing a few Chinese made widgets and your preferred drugs. Just shut the eff up, cover your disgusting face that no one wants to see, and do what you are ordered to do.

There is a bright side though in case you forgot. All states have a lottery and you could be a rich person if you only pay for a ticket. So tell those naysayers that they don't know what they are talking about with their so-called last mile and freedumbs arguments because you know you are not free. Heck you can even get to feel superior. Which is nice, so you have that going for you.
 
2020-11-23 9:38:57 PM  

Algebrat: jph: Eravior: I'll just take all of them. That's like 287% effective or something?

This is something I'd love to find out about. Pfizer and Moderna's vaccines use different techniques, but the Oxford/AstraZeneca vaccine uses Different Science™, so perhaps the ultimate answer will be some sort of cocktail.

So vaccines follow Jager rules?  Best served cold or in a cocktail. Would have been better to not need it, but you're glad it's there when you're in a bind.


Only bad occurs with that poison.
 
2020-11-23 9:44:26 PM  

StoPPeRmobile: Weatherkiss: Keep your vaccine. I'll just be snorting Lysol up my nostrils and praying to Jesus Christ to save me from the 'rona.

Yeah! Let's just keep the populace wearing masks in public forever. Only a monster would not accept the risk that some might cause great harm to many for the personal feeling of security of all obscuring their identity in public.

Besides, we have eradicated all of the enemies that this empire has aquired through our great acceptance policy of agreeable acceptance of those that, I don't think I can say the politically acceptable rationale of this but I have been assured by a small portion of the population that if I do this I am not a hater. The entire planet wants nothing but unicorn farts and puppy smiles for all of us that choos to live here and we should shame all that do not accept the covering of their identity.

Geez people! We are not individuals with choices, we are but faceless workers, put on this planet, to serve our betters. Get the eff over yourselves, cover your ugly face, smell your breath constantly, and serve our masters. It can't be any more simple than that. You do not have a choice.

I am sick and tired that so-called people thinking that they have a choice. You have no choice besides purchasing a few Chinese made widgets and your preferred drugs. Just shut the eff up, cover your disgusting face that no one wants to see, and do what you are ordered to do.

There is a bright side though in case you forgot. All states have a lottery and you could be a rich person if you only pay for a ticket. So tell those naysayers that they don't know what they are talking about with their so-called last mile and freedumbs arguments because you know you are not free. Heck you can even get to feel superior. Which is nice, so you have that going for you.


Vaccine should be available around April. You can wear a mask until that long at least. Your inconvenience is not more important than the lives of people.
 
2020-11-23 9:45:08 PM  

jph: This is exactly it - efficacy is actually 90%.


In a study of 20k people, only 3k received the dosing regimen that showed 90% efficacy. That arm wasn't even supposed to be part of the study - it was a dosing error. It's encouraging, but I'd like to see another study with that regimen and placebo.

Post-hoc analysis of an accidental, underpowered treatment arm just doesn't fill me with confidence.
 
2020-11-23 9:50:28 PM  

StoPPeRmobile: Algebrat: jph: Eravior: I'll just take all of them. That's like 287% effective or something?

This is something I'd love to find out about. Pfizer and Moderna's vaccines use different techniques, but the Oxford/AstraZeneca vaccine uses Different Science™, so perhaps the ultimate answer will be some sort of cocktail.

So vaccines follow Jager rules?  Best served cold or in a cocktail. Would have been better to not need it, but you're glad it's there when you're in a bind.

Only bad occurs with that poison.


Ok, sure, it leads directly to being penetrated with a little prick, but the alternative is being alone forever.
 
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