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(CNBC)   AstraZeneca is basically building the Chrysler of Covid vaccines   ( divider line
    More: Followup  
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3192 clicks; posted to Main » on 23 Nov 2020 at 11:50 AM (20 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook

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2020-11-23 10:02:19 AM  
34 votes:'s filled with soft Corinthian leather and delivered by Ricardo Montalban?
2020-11-23 10:12:19 AM  
26 votes:
All the sensors will blow out at 50,000 miles?
2020-11-23 11:56:46 AM  
12 votes:
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2020-11-23 12:00:21 PM  
8 votes:
A nice Reliant Vaccine.
2020-11-23 12:10:54 PM  
6 votes:
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2020-11-23 11:58:59 AM  
6 votes:
I didn't realize vaccines could leak oil. The more you know I guess.
2020-11-23 11:55:08 AM  
4 votes:
Appealing only to a few people?
2020-11-23 11:59:29 AM  
3 votes:

taintbaggins: [Fark user image 425x253]

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An American Trabant!

/ shiny metal boxes, etc.
2020-11-23 11:56:42 AM  
3 votes:
It's a PT cruiser?
2020-11-23 12:53:56 PM  
2 votes:

The_Homeless_Guy: kevlar51: Honestly, 70% would normally be viewed as pretty damn good, as far as vaccines go. Flu vaccines typically come in at 60%. It's just overshadowed by the 90-95 percenters.

Also, as the article states, it appears that when it is not 100% percent effective it still lessons the symptoms (it says that there were no hospitalizations in the vaccination arm). That is good enough as well.

Well what about the rest of the body?  What was the percentage then, huh?
2020-11-23 12:19:21 PM  
2 votes:

Marcus Aurelius: All the sensors will blow out at 50,000 miles?

It was so thoughtful how they shared that trait with certain Jeep models after the merger.
2020-11-23 4:09:48 PM  
1 vote:

Ivo Shandor: From the "are you farking kidding me?" department...

Dosing error turns into lucky punch for AstraZeneca and Oxford

Wow. This can only be the work of time travelers who want to provide a gentle guiding hand without it being totally obvious someone's farking with the timeline.
2020-11-23 1:30:35 PM  
1 vote:

goodncold: ChiliBoots: I hereby demand that I be given a Fark account: Tr0mBoNe: One showed an effectiveness of 90% when trial participants received a half dose, followed by a full dose at least one month apart.
The other dosing regimen showed 62% efficacy when given as two full doses at least one month apart.

That's... interesting.

Interesting bordering on WTF?

I think we need to hold off on this particular vaccine until more data comes in and if this hold, a solid explanation of why the 1/2->1 dosing is so much more effective than 1->1 dosing.

Doubly so when none of the other candidates has shown a pattern like this so far.

The Oxford vaccine is an adenovirus vectored vaccine as opposed to the mRNA vaccines from Pfizer and Moderna. The major issue with vectored vaccines is pre-existing immunity to the vector portion so that the payload bits can't gain access to the immunological machinery. I'd hypothesize that the higher prime dose induces too great of an immunity to the vector, so when it's time to introduce the booster, it's rebuffed by the immune response to the adenovirus portion.

mRNA vaccines don't have this issue.

The downside to the mRNA vaccines is that these will be the first ones to be used massively on humans and are the first ones to basically operate at the genetic level. could be saved...or you could be turned into crab people.

Did-a-chak, did-a-chum
2020-11-23 12:59:43 PM  
1 vote:
Ed Rooney's Car Gets Towed
2020-11-23 12:08:07 PM  
1 vote:
So how are we gonna pass this stuff out?

By race or....?
2020-11-23 12:02:39 PM  
1 vote:
Bench seating in the front to more easily get road head?
2020-11-23 11:57:47 AM  
1 vote:
Lee Iacocca will avoid snorting it, unlike his competitor, Mr. DeLorean?
2020-11-23 11:55:28 AM  
1 vote:

FirstNationalBastard:'s filled with soft Corinthian leather and delivered by Ricardo Montalban?

Marcus Aurelius: All the sensors will blow out at 50,000 miles?

No, no. It will be "The Best You Can Get".
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