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(Medical Xpress)   In Re Coronavirus - "Everything that guy just said was bullshiat. Thank You"   (medicalxpress.com) divider line
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1068 clicks; posted to STEM » on 30 Oct 2020 at 1:18 PM (4 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



14 Comments     (+0 »)
 
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2020-10-30 1:30:02 PM  
"The (Carl) Icahn School of Medicine (and Get the Fark Back to Work, Maggots) at Mount Sinai and published October 28,... "
 
2020-10-30 1:37:17 PM  
5 months of antibody response is... insufficient for a flu-like disease that's going to recur on a 12-month cycle.
 
2020-10-30 1:53:31 PM  
That would be totally relevant and great if maybe we infected everyone in the world with it at the same time. Then the virus would be completely eliminated along with a not insignificant portion of the world's populace and economy. Unfortunately, lax and disproportionate response to the virus has been allowed it to become endemic and you can just catch it again once your antibody response drops enough.
 
2020-10-30 3:22:39 PM  

FrancoFile: 5 months of antibody response is... insufficient for a flu-like disease that's going to recur on a 12-month cycle.


Were the 6 million Americans it infected during summer not sufficient to entirely dispel any notion that it has a seasonality?

Things like the common cold or the flu, which have basic reproductive numbers between 1.1 and 1.5 usually, have seasons to them. The 'rona has a reproductive number between 3 and 6. There's no season to that.
 
2020-10-30 3:25:04 PM  

erik-k: FrancoFile: 5 months of antibody response is... insufficient for a flu-like disease that's going to recur on a 12-month cycle.

Were the 6 million Americans it infected during summer not sufficient to entirely dispel any notion that it has a seasonality?

Things like the common cold or the flu, which have basic reproductive numbers between 1.1 and 1.5 usually, have seasons to them. The 'rona has a reproductive number between 3 and 6. There's no season to that.



True.  During the initial infection phase, it's been seasonless.

But if it persists, it will have seasonal peaks when people move their activities indoors, and when other seasonal diseases overload people's immune systems and/or the healthcare system.

In any event, none of this immune system news does anything to support a herd immunity approach as a valid strategy.
 
2020-10-30 4:05:41 PM  
"...strong antibody response to SARS-CoV-2 that does not decline rapidly."

WOOHOO!

"...is relatively stable for at least five months, ..."

Well, at least a bit, then...

"...the response is maintained for many months, ..."

So, 5 = 'many' ???

WTF am I reading???
 
2020-10-30 4:11:13 PM  

BenSaw2: "...strong antibody response to SARS-CoV-2 that does not decline rapidly."

WOOHOO!

"...is relatively stable for at least five months, ..."

Well, at least a bit, then...

"...the response is maintained for many months, ..."

So, 5 = 'many' ???

WTF am I reading???


How many months of the pandemic have they been tracking individual patients?

Is at least 5 months because that's the timeline we have. No one is saying it's a cap yet. It is sustaining immune response so far. Short version, that's good.
 
2020-10-30 4:40:50 PM  

FrancoFile: erik-k: FrancoFile: 5 months of antibody response is... insufficient for a flu-like disease that's going to recur on a 12-month cycle.

Were the 6 million Americans it infected during summer not sufficient to entirely dispel any notion that it has a seasonality?

Things like the common cold or the flu, which have basic reproductive numbers between 1.1 and 1.5 usually, have seasons to them. The 'rona has a reproductive number between 3 and 6. There's no season to that.


True.  During the initial infection phase, it's been seasonless.

But if it persists, it will have seasonal peaks when people move their activities indoors, and when other seasonal diseases overload people's immune systems and/or the healthcare system.

In any event, none of this immune system news does anything to support a herd immunity approach as a valid strategy.


I -still- can't imagine how anyone could actually believe 'herd immunity' was a viable strategy without a vaccine (as opposed to the sociopaths who knowingly lie that it is).

Think about it, dipshiats - if communicable viral infections worked that way, shouldn't they all have eradicated themselves?
 
2020-10-30 5:05:29 PM  

erik-k: FrancoFile: erik-k: FrancoFile: 5 months of antibody response is... insufficient for a flu-like disease that's going to recur on a 12-month cycle.

Were the 6 million Americans it infected during summer not sufficient to entirely dispel any notion that it has a seasonality?

Things like the common cold or the flu, which have basic reproductive numbers between 1.1 and 1.5 usually, have seasons to them. The 'rona has a reproductive number between 3 and 6. There's no season to that.


True.  During the initial infection phase, it's been seasonless.

But if it persists, it will have seasonal peaks when people move their activities indoors, and when other seasonal diseases overload people's immune systems and/or the healthcare system.

In any event, none of this immune system news does anything to support a herd immunity approach as a valid strategy.

I -still- can't imagine how anyone could actually believe 'herd immunity' was a viable strategy without a vaccine (as opposed to the sociopaths who knowingly lie that it is).

Think about it, dipshiats - if communicable viral infections worked that way, shouldn't they all have eradicated themselves?


I agree that without a vaccine, herd immunity is just so much nonsense - thinning the herd, more like.

But communicable viral diseases which cause lifelong immunity in the survivors would still persist, just because new, non-immune individuals get added to the population, with each parent taking their baby home from the maternity ward....
 
2020-10-30 5:45:58 PM  

BenSaw2: "...strong antibody response to SARS-CoV-2 that does not decline rapidly."

WOOHOO!

"...is relatively stable for at least five months, ..."

Well, at least a bit, then...

"...the response is maintained for many months, ..."

So, 5 = 'many' ???

WTF am I reading???


"Dozens of us!"
 
2020-10-30 6:33:30 PM  
But some unqualified blogger for the NYT told me that the last study, which hadn't been reviewed yet, was a done deal!!!11.
 
2020-10-30 8:00:00 PM  
I thought the report saying that antibodies didn't last more than a couple of months was from people that were asymptomatic, which isn't the same demographic as this report.
 
2020-10-30 10:46:36 PM  
FTFA: Another important and outstanding question in the scientific community is the longevity of the antibody response to the spike protein. To answer that question, the team recalled 121 plasma donors at a variety of titer levels for repeat antibody testing at approximately 3 months and 5 months post-symptom onset. When comparing overall titers, they saw a slight drop from a geometric mean titer (GMT) of 764 to a GMT of 690 from the first to second testing time point and another drop to a GMT of 404 for the last testing time point,

So there was a 10% drop after 3 months and a 47% drop after 5 months.
That's not especially reassuring.
 
2020-10-31 8:48:54 PM  

NotARocketScientist: FTFA: Another important and outstanding question in the scientific community is the longevity of the antibody response to the spike protein. To answer that question, the team recalled 121 plasma donors at a variety of titer levels for repeat antibody testing at approximately 3 months and 5 months post-symptom onset. When comparing overall titers, they saw a slight drop from a geometric mean titer (GMT) of 764 to a GMT of 690 from the first to second testing time point and another drop to a GMT of 404 for the last testing time point,

So there was a 10% drop after 3 months and a 47% drop after 5 months.
That's not especially reassuring.


What level is sufficient to prevent reinvention?

SARS from 17 years ago gave immunity that has persisted to this day that extends to this virus as well. So I am optimistic that a proper vaccine may fix this.
 
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