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(Yahoo)   In rare GOOD Covid news, the CDC has a very effective treatment for the version killing kids (MIS-C). Of a test group of 33, the mortality rate was 0 percent, and 82 percent had been discharged from the hospital   (yahoo.com) divider line
    More: Spiffy, Immune system, inflammatory syndrome, hallmark symptom of MIS-C, Antibody, MIS-C., Blood, Disease Control, blood plasma  
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2905 clicks; posted to Main » on 21 May 2020 at 5:07 PM (2 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook



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2020-05-21 4:15:39 PM  
One can always appreciate good news during this pandemic.
 
2020-05-21 4:21:27 PM  
PMIS.
 
2020-05-21 4:35:00 PM  
That's great news, but no control group for the study?
 
2020-05-21 4:49:51 PM  
... but it isn't killing kids.

It is maiming them.
 
2020-05-21 4:57:57 PM  
They are treating the inflammation, not the infection.
Still good news.
 
2020-05-21 5:07:39 PM  
And the control group?
 
2020-05-21 5:09:48 PM  
 
2020-05-21 5:12:58 PM  

cretinbob: They are treating the inflammation, not the infection.
Still good news.


Yep - I'm all for some genuinely good news in this months-long mess, and this fits the bill.
 
2020-05-21 5:13:03 PM  
another missy that was bad...
encrypted-tbn0.gstatic.comView Full Size
 
2020-05-21 5:13:52 PM  
But the ET-C version killing grandma is still unchecked.
 
2020-05-21 5:15:40 PM  

I hereby demand that I be given a Fark account: And the control group?


The kids who died before the treatment was used
 
2020-05-21 5:15:45 PM  
But what if you dislike children?
 
2020-05-21 5:18:32 PM  
I dislike children. What can Trump so for me?!
 
2020-05-21 5:18:38 PM  
Still no cure for trump.
 
2020-05-21 5:24:26 PM  

camarugala: I dislike children. What can Trump so for me?!


Discord.
 
2020-05-21 5:25:34 PM  
media0.giphy.comView Full Size
 
2020-05-21 5:25:46 PM  
So if I get exposed to COVID-19 from some knuckledragging antivax protester while waiting in line to be vaccinated which will kick in first, the vaccine or the 'rona?
 
2020-05-21 5:26:26 PM  

GardenWeasel: That's great news, but no control group for the study?


Oh ya, let's give 30 other kids with Covid a sugar pill.
 
2020-05-21 5:26:37 PM  

Breaker Moran: camarugala: I dislike children. What can Trump so for me?!

Discord.


Maybe find a Pizza Hut with a basement?
 
2020-05-21 5:31:11 PM  
So which evangelist preacher can we credit for this ? There was a laying on of hands and much gibbering was there not?
 
2020-05-21 5:41:28 PM  
So it says it's giving the kids plasma rich in a variety of antibodies to basically let the body think it's got the immune response handled and doesn't have to go overboard with the response.

With adults with advanced COVID, they can also get the out of control immune response with the cytokine storm. Without knowing anything, I wonder if there's any benefit in doing the same thing? Introduce the plasma with various antibodies to lessen the overboard immune response.
 
2020-05-21 5:42:11 PM  
I need all the good news I can get.
 
2020-05-21 5:43:15 PM  

fragMasterFlash: So if I get exposed to COVID-19 from some knuckledragging antivax protester while waiting in line to be vaccinated which will kick in first, the vaccine or the 'rona?


Yes
 
2020-05-21 5:49:55 PM  
MIS-C is not a version of Covid-19, it's something that seems to be caused by it. I really hope it does not follow the kids all their lives or even "only" while they're kids. If so I hope the treatment is cheap in places with capitalist healthcare.
 
2020-05-21 5:54:14 PM  
Whar orange man bad in story?
 
2020-05-21 5:55:14 PM  

bhcompy: I hereby demand that I be given a Fark account: And the control group?

The kids who died before the treatment was used


The problem with that is care evolves all the time. We've been burned by this too many times.

I hope this treatment helps, but we don't know without proper random selected double-blind controlled trials.
 
2020-05-21 5:55:43 PM  

SirDigbyChickenCaesar: Whar orange man bad in story?


In a woodchipper if there's any justice in this world.
 
2020-05-21 5:58:09 PM  

I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.


So just to be clear, just in case anyone is reading this, you want to kill a sitting president.
 
2020-05-21 6:08:58 PM  

SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.


Fark user imageView Full Size
 
2020-05-21 6:12:41 PM  

SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.


There's a difference between "wanting to kill" and "wanting to die."
 
2020-05-21 6:13:19 PM  

SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.


He didn't say he wanted to put him in a wood-chipper. He merely said he hoped that the man was in a wood chipper.

Much like saying I have no desire to kill evil nazi racist bastards, but I'm very hopeful that they'll get Covid-19 and die and won't feel bad about it.
 
2020-05-21 6:14:42 PM  

talkertopc: MIS-C is not a version of Covid-19, it's something that seems to be caused by it. I really hope it does not follow the kids all their lives or even "only" while they're kids. If so I hope the treatment is cheap in places with capitalist healthcare.


the last time something foul caused something, we got Mis-C Elliot.

/i know, I know.
 
2020-05-21 6:19:58 PM  
Subby this is Fark get that shiat outta here.
 
2020-05-21 6:20:33 PM  

Breaker Moran: camarugala: I dislike children. What can Trump so for me?!

Discord.


Well done.
 
2020-05-21 6:21:26 PM  

Kit Fister: SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.

He didn't say he wanted to put him in a wood-chipper. He merely said he hoped that the man was in a wood chipper.

Much like saying I have no desire to kill evil nazi racist bastards, but I'm very hopeful that they'll get Covid-19 and die and won't feel bad about it.


Fark it, I'll do it.  I'll even provide the wood chipper and the plastic bags.

Someone bring me Trump.
 
2020-05-21 6:29:07 PM  

Rent Party: Kit Fister: SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.

He didn't say he wanted to put him in a wood-chipper. He merely said he hoped that the man was in a wood chipper.

Much like saying I have no desire to kill evil nazi racist bastards, but I'm very hopeful that they'll get Covid-19 and die and won't feel bad about it.

Fark it, I'll do it.  I'll even provide the wood chipper and the plastic bags.

Someone bring me Trump.


Were that I had but 3 months to live.

/I regret that I have but one life to give for my country.
 
2020-05-21 6:30:13 PM  

Rent Party: Kit Fister: SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.

He didn't say he wanted to put him in a wood-chipper. He merely said he hoped that the man was in a wood chipper.

Much like saying I have no desire to kill evil nazi racist bastards, but I'm very hopeful that they'll get Covid-19 and die and won't feel bad about it.

Fark it, I'll do it.  I'll even provide the wood chipper and the plastic bags.

Someone bring me Trump.


Oh, and I lied. If it was legal, I'd kill every violent nazi scumbag that had the balls to threaten violence on peaceful peoples and destroy the lives of innocents.
 
2020-05-21 6:31:04 PM  

SanityIsAFullTimeJob: So it says it's giving the kids plasma rich in a variety of antibodies to basically let the body think it's got the immune response handled and doesn't have to go overboard with the response.

With adults with advanced COVID, they can also get the out of control immune response with the cytokine storm. Without knowing anything, I wonder if there's any benefit in doing the same thing? Introduce the plasma with various antibodies to lessen the overboard immune response.


Early COVID-19 trials in interferon-beta look promising, working on a diff aspect of the immune system. This is given to people with MS to take down the autoimmune response.  https://www.thelancet.com/journals/la​n​cet/article/PIIS0140-6736(20)31042-4/f​ulltext

Kids & adults are different in critical ways. Esp in the immune system.
 
2020-05-21 6:49:44 PM  
That's great news; I have to say though that MIS-C is a garbage name when they just could have called it Pediatric COVID Syndrome.
 
2020-05-21 7:00:42 PM  

WithinReason: GardenWeasel: That's great news, but no control group for the study?

Oh ya, let's give 30 other kids with Covid a sugar pill.


That's how science works, unfortunately.
 
2020-05-21 7:06:05 PM  
I am usually the guy who can explain stuff, and not the one confused... but,

How do diseases that you fight off cause new diseases? I know that there are other examples, but I don't understand how this happens. What is the process?

And if CoViD-19 causes MIS-C right now in some children, does that mean it's likely to cause other complications for other patients later on?
 
2020-05-21 7:27:50 PM  
A syndrome isn't a disease, it's a collection of symptoms.
 
2020-05-21 7:37:00 PM  

GardenWeasel: WithinReason: GardenWeasel: That's great news, but no control group for the study?

Oh ya, let's give 30 other kids with Covid a sugar pill.

That's how science works, unfortunately.


FTFA: "Although doctors aren't exactly sure how IVIG helps with MIS-C, the theory is..."

I'll be that guy - why isn't the media foaming at the mouth that this wasn't a double-blind study with a larger sample size and a control group?  I mean, this was a previously approved therapy for a new application, on a new disease, that just happened to exhibit similar symptoms to an unrelated one.  One would think if the mechanisms of how a therapy addresses symptoms are what you're looking for, to at least keep you from having to go on a ventilator, then maybe you'd want to try other therapies for new applications.  Perhaps therapies with known side effects, kept restricted in use to people that test out as able to handle them.  Therapies that have been used by a LOT of people, for a LONG time, as an alternative to just letting people die.  I wonder who'd suggest such a thing?

Fark user imageView Full Size


Pfft.  That's just crazy talk.  No civilized country would go out on a limb and bulk buy an untested drug.
 
2020-05-21 7:42:05 PM  

fragMasterFlash: So if I get exposed to COVID-19 from some knuckledragging antivax protester while waiting in line to be vaccinated which will kick in first, the vaccine or the 'rona?


Post-exposure effects of vaccines are usually worthwhile - the more prompt the vaccination following the exposure the better. Getting the rabies vaccine after being infected with the rabies virus has a 100% effective rate, for example.

You're on terra incognita when it comes to a vaccine for any coronavirus, much less the novel coronavirus Covid-19 which seems to keep springing so many surprises, so we'll only know how effective a treatment that is when we have one, but it seems quite likely that it would be helpful.
 
2020-05-21 7:54:23 PM  

I hereby demand that I be given a Fark account: bhcompy: I hereby demand that I be given a Fark account: And the control group?

The kids who died before the treatment was used

The problem with that is care evolves all the time. We've been burned by this too many times.

I hope this treatment helps, but we don't know without proper random selected double-blind controlled trials.


Fair enough, but going from kids dying to no kids dying is not a subtle change in outcome.
 
2020-05-21 8:01:42 PM  

Prussian_Roulette: GardenWeasel: WithinReason: GardenWeasel: That's great news, but no control group for the study?

Oh ya, let's give 30 other kids with Covid a sugar pill.

That's how science works, unfortunately.

FTFA: "Although doctors aren't exactly sure how IVIG helps with MIS-C, the theory is..."

I'll be that guy - why isn't the media foaming at the mouth that this wasn't a double-blind study with a larger sample size and a control group?  I mean, this was a previously approved therapy for a new application, on a new disease, that just happened to exhibit similar symptoms to an unrelated one.  One would think if the mechanisms of how a therapy addresses symptoms are what you're looking for, to at least keep you from having to go on a ventilator, then maybe you'd want to try other therapies for new applications.  Perhaps therapies with known side effects, kept restricted in use to people that test out as able to handle them.  Therapies that have been used by a LOT of people, for a LONG time, as an alternative to just letting people die.  I wonder who'd suggest such a thing?

[Fark user image 245x183] [View Full Size image _x_]

Pfft.  That's just crazy talk.  No civilized country would go out on a limb and bulk buy an untested drug.


And once those treatments are tested, and found not to be beneficial, you'd stop using them and tell people not to bother, right?
 
2020-05-21 8:07:07 PM  

Gooch: That's great news; I have to say though that MIS-C is a garbage name when they just could have called it Pediatric COVID Syndrome.


That would require proof that Sars-CoV-2 or COVID-19 directly causes MIS-C, which we don't have.

While it might sound like it would be a hell of a coincidence if it didn't, there could be something else going on. For example, Legionnaire's Disease is in the news now that large office buildings are preparing to open back up again. If nobody went around and flushed toilets and ran taps regularly while the buildings were shut down, the bacteria that causes Legionnaire's Disease can take off in a big way.

Cities and towns have been operating in very non-typical fashions for an extended period of time, so bacteria of all sorts that would not normally be a problem might be flourishing now. Children, not being in school, have also not been following normal patterns of behavior and movement and may be getting exposed to things (not necessarily even bacteria or viruses) they normally wouldn't be.
 
2020-05-21 8:15:05 PM  

evilsofa: Children, not being in school, have also not been following normal patterns of behavior and movement and may be getting exposed to things (not necessarily even bacteria or viruses) they normally wouldn't be.


Yes, those things at home where they already spend at least 12 hours a day even when school is in session
 
2020-05-21 8:17:46 PM  

Kit Fister: Rent Party: Kit Fister: SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.

He didn't say he wanted to put him in a wood-chipper. He merely said he hoped that the man was in a wood chipper.

Much like saying I have no desire to kill evil nazi racist bastards, but I'm very hopeful that they'll get Covid-19 and die and won't feel bad about it.

Fark it, I'll do it.  I'll even provide the wood chipper and the plastic bags.

Someone bring me Trump.

Were that I had but 3 months to live.

/I regret that I have but one life to give for my country.


so you are saying you'd kill the president?
 
2020-05-21 8:37:27 PM  

SirDigbyChickenCaesar: Kit Fister: Rent Party: Kit Fister: SirDigbyChickenCaesar: I hereby demand that I be given a Fark account: SirDigbyChickenCaesar: Whar orange man bad in story?

In a woodchipper if there's any justice in this world.

So just to be clear, just in case anyone is reading this, you want to kill a sitting president.

He didn't say he wanted to put him in a wood-chipper. He merely said he hoped that the man was in a wood chipper.

Much like saying I have no desire to kill evil nazi racist bastards, but I'm very hopeful that they'll get Covid-19 and die and won't feel bad about it.

Fark it, I'll do it.  I'll even provide the wood chipper and the plastic bags.

Someone bring me Trump.

Were that I had but 3 months to live.

/I regret that I have but one life to give for my country.

so you are saying you'd kill the president?


I made no such threat or claim. I just wouldn't go out of my way to help him.

/no, I will not threaten the president and commit a felony no matter how much you try to bait someone into it.
 
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