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(Wired UK)   Scientists believe they've found a way to cure people with HIV and Zika by infecting them with a CRISPR virus that infects those viruses and edits out the DNA they need for survival. Other phases of the treatment involve needle snakes and gorillas   ( wired.co.uk) divider line
    More: Interesting, gene therapy, Gene, Immune system, HIV, Bacteria, gene therapy trial, AIDS, virus  
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3195 clicks; posted to Main » on 19 May 2017 at 10:20 PM (29 weeks ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



79 Comments     (+0 »)
 
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2017-05-19 03:06:42 PM  
Better than being infected with the CRISPEN virus which just makes you a creepier Andy Koffman-lite.
 
2017-05-19 09:51:48 PM  
HOW CRISPR-CAS13A ENZYMES BEHAVE LIKE PAC-MAN

wakka wakkaaaa
 
2017-05-19 10:23:00 PM  
Isn't this the plot of a BUNCH of apocalypse-virus movies?
 
2017-05-19 10:25:25 PM  
What could possibly go wrong?

/nothing, nothing could go wrong
 
2017-05-19 10:26:20 PM  
A friend of mine recently died from HIV related lymphoma, so this is a little too late for him and many others.  Yes, he was healthy and on existing meds.
Great development tho.
 
2017-05-19 10:26:41 PM  
I thought the Zima virus cured itself in 2008
 
2017-05-19 10:27:19 PM  
You know I've had of of those in my fridge for years but I didn't know it could do that.
 
2017-05-19 10:28:10 PM  
Scientists say they can then *ease* them onto a sister virus, Ebola..

//Results not guaranteed
//Prepayment Required
 
2017-05-19 10:30:36 PM  
The gorilla enema is really gonna suck
 
2017-05-19 10:31:11 PM  
Kudos to these scientists!
 
2017-05-19 10:31:24 PM  
Brad Pitt's WWZ anyone?
 
2017-05-19 10:31:47 PM  

Short Victoria's War: What could possibly go wrong?

/nothing, nothing could go wrong


I just can't wait until a rogue biologist creates a human CRISPR virus and turns us all into gingers or something.  Maybe even a long play like turning off something that makes us more susceptible to skin caner.
 
2017-05-19 10:32:09 PM  
Do you want zombie hordes?, because this is how you get zombie hordes.
 
2017-05-19 10:33:56 PM  
The CRISPR virus keeps your vegetables fresh.
 
2017-05-19 10:41:48 PM  
That's the brilliant part! When winter comes around, the gorillas will just freeze to death
 
2017-05-19 10:44:33 PM  
Crispr cas9 will change the world. One of the biggest discoveries in science.
 
2017-05-19 10:47:02 PM  
Why don't we just build nanobot robots that beat up the AIDS virus with tiny baseball bats?

\copyright pending Amish Tech 2017
 
2017-05-19 10:47:57 PM  

mattj1984: Isn't this the plot of a BUNCH of apocalypse-virus movies?


And books.  I am Legend off the top of my head.
 
2017-05-19 10:50:20 PM  
O that we now had here but one ten thousand of those viruses in England that do no work to-day.
 
2017-05-19 10:50:33 PM  

Short Victoria's War: What could possibly go wrong?

/nothing, nothing could go wrong


Nothing could possably go wrong, Possibly go wrong, Hmmm...that is the first thing that's ever gone wrong.
 
2017-05-19 10:56:43 PM  

NathanAllen: Brad Pitt's WWZ anyone?


There's no cure for that movie


/ seriously, what was the zombie doing in the cupboard for 5 hours. Browsing skymall?
 
2017-05-19 11:01:49 PM  

puffy999: That's the brilliant part! When winter comes around, the gorillas will just freeze to death


This rock keeps tigers away.
 
2017-05-19 11:01:52 PM  
I really enjoyed the reference.
 
2017-05-19 11:02:07 PM  
Ever since AIDS got on the radar, I would hear of some prospective cure or another, which would fizzle.

I would remember the baby steps were in the form of drug cocktails that eventually went down to a pill and gradually the funerals tapered off as the disease went from incurable to manageable.

Hoping for that silver bullet. Might even unlock cures to cancer.
 
2017-05-19 11:04:07 PM  
img.fark.netView Full Size


A great movie, if somewhat scientifically untenable. But at least it doesn't have infectious zombies.
 
2017-05-19 11:13:54 PM  
And hold their manhoods cheap whiles any speaks
That infected us with Saint Crisprs virus.
 
2017-05-19 11:15:34 PM  
Please don't be Umbrella Corporation , please don't be Umbrella Corporation... Reads story...Phew, we may have dodged a bullet this time.
 
2017-05-19 11:20:29 PM  

abhorrent1: The gorilla enema is really gonna suck


It's gonna be worse when you have to freeze them to kill them. Gorilla poopsicles for everyone!
 
2017-05-19 11:23:18 PM  
Let's do this thing.
 
2017-05-19 11:31:09 PM  
Taken to its logical conclusion, this technique will be used to target genes that signal telomeres to shorten as cells age, producing many of the effects we attribute to aging. Fountain of youth? Sure, if you can afford it.
 
2017-05-19 11:34:03 PM  
I've been looking forward to this use of CRISPR for years now. I've got a genetic defect that contributes to my clinical depression; it would be nice to be able to edit my DNA to fix it.
 
2017-05-19 11:37:26 PM  

fragMasterFlash: Taken to its logical conclusion, this technique will be used to target genes that signal telomeres to shorten as cells age, producing many of the effects we attribute to aging. Fountain of youth? Sure, if you can afford it.


I was just thinking of that.  If insurance was smart, insurance would cover it.  Imagine a world where everyone had the health problems of 20 year olds.
 
2017-05-19 11:38:03 PM  
Now I always wash my hands after handling  the hiv and zica , a wake up call.
 
2017-05-19 11:40:10 PM  

RoomFullOfMonkeys: I've been looking forward to this use of CRISPR for years now. I've got a genetic defect that contributes to my clinical depression; it would be nice to be able to edit my DNA to fix it.


Care to elaborate? That's very interesting.
 
2017-05-19 11:45:46 PM  
So, once again, smart people get to do cool stuff -and- save the world? How is that fare?
 
2017-05-19 11:47:03 PM  

Ghastly: Better than being infected with the CRISPEN virus which just makes you a creepier Andy Koffman-lite.


BWAHAHAHAHAHA!!!
 
2017-05-20 12:01:15 AM  

RogermcAllen: Short Victoria's War: What could possibly go wrong?

/nothing, nothing could go wrong

I just can't wait until a rogue biologist creates a human CRISPR virus and turns us all into gingers or something.  Maybe even a long play like turning off something that makes us more susceptible to skin caner.


I doubt we are very far away from being able to create killer synthetic viruses as weapons.  I'm sure that will be awesome.
 
2017-05-20 12:02:22 AM  
The cure for syphilis used to be malaria. Because they had a cure for malaria and the body fighting the malaria would kill the syphilis in the process.
This is not a new concept.
 
2017-05-20 12:02:35 AM  

Pointy Tail of Satan: [img.fark.net image 467x471]

A great movie, if somewhat scientifically untenable. But at least it doesn't have infectious zombies.


Read the book a million years ago.
 
2017-05-20 12:20:41 AM  
Just so you know, the early treatment for syphyllis was to infect those with syphyllis with a heavy dose of malaria. The fever associated with malaria kills off the symptoms of syphyllis in about 35 percent of patients treated. The winner of the 1929 or 28 winner of the Nobel in medicine did this.

The more you know, or chose to not know.
 
2017-05-20 12:24:18 AM  
This will obviously get quietly buried. Big pharma doesn't like cures.

Why sell a one-time cure when you can sell a treatment for the rest of the patient's life?
 
2017-05-20 12:24:41 AM  
img.fark.netView Full Size


"I want more life, f***er"
 
2017-05-20 12:27:14 AM  
img.fark.netView Full Size
 
2017-05-20 12:38:22 AM  
Will it turn you into some laugh-inducing CGI "villain"?
img.fark.netView Full Size
 
2017-05-20 01:30:03 AM  
This won't work as a cure.  The issue with HIV is the infected CD4+ reservoirs - such as in the lymph - that we have no accessible way of attacking.  This will make for a terrific treatment, however.  The current drugs are incredibly toxic, and non-adherence is the main (other than cost) issue with them due to side effects.  A CRISPR attack would bypass all of that hot garbage.  Article suggests this will also clean infected cells of provirus - that is awesome.
 
2017-05-20 01:41:40 AM  

Russ1642: Will it turn you into some laugh-inducing CGI "villain"?
[img.fark.net image 425x265]


Don't worry
About a thing
Every little thing
Is gonna be alright
 
2017-05-20 02:02:36 AM  

The Beatings Will Continue Until Morale Improves: I thought the Zima virus cured itself in 2008


I was under the impression the viruses don't have DNA.
 
2017-05-20 02:25:26 AM  

Sensei Can You See: The Beatings Will Continue Until Morale Improves: I thought the Zima virus cured itself in 2008

I was under the impression the viruses don't have DNA.


There are RNA viruses and DNA viruses.  Measles, Mumps, Rubella, the Common Cold, Flu, Ebola, Rabies, HIV, etc. are all RNA viruses.  Smallpox, Chicken pox, Herpes, HPV, etc. are all DNA viruses.
 
2017-05-20 02:26:34 AM  
While that does sound like an odd solution to people who don't get how retro viruses work, it's technically feasible, I just assumed stuff like that was over a decade away.
 
2017-05-20 02:27:40 AM  
Yeah cool cool, cool cool.  I'm just... gonna go buy a lot of canned beans now and maybe some hazmat level face filters.
 
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