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(Mother Nature Network)   The next time you go to the dentist and intensely feel the cold steel bite of his drill spinning vigorously into your decaying, exposed, cavity-riddled tooth, you can now blame a genetic mutation for why the anesthesia didn't work   (mnn.com ) divider line
    More: Scary, Anesthesia, Local anesthetic resistance, Sodium, sodium channels, specific sodium channel, Local anesthetic, Sodium channel, Yale University School  
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2541 clicks; posted to Main » on 11 Jan 2017 at 9:30 AM (6 days ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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6 days ago  
For ~25 years I thought dental anaesthetics had no effect on me.

As a kid, back around 1991 I had to have a filling in one tooth.  The anaesthetic numbed my mouth and I was talking funny. . .but I felt EVERYTHING when the dentist drilled me.  He wouldn't believe that I could feel everything and was shouting at me to stop screaming.  It was very, VERY unpleasant and rather mentally scarring to be forcibly held down by the hygenist while the dentist drills, feeling everything the whole way.

It left me with a life-long fear of dentists and dental work.

I finally went to a dentist last month.  The only other dental work I'd had in my whole life was having my wisdom teeth cut out (because the Army required it), and they knocked me out for that one.  I looked up a dentist that would do sedation dentistry, since I thought I was apparently immune to novocaine and would need to be knocked out to do anything to me.

They did a little test.  Nope, not immune.  They were able to do all the dental work I really, really needed with just a local, and I feel a helluva lot better afterwards.  It turns out that small-town dentist was just really incompetent and didn't numb the right part of my mouth, and refused to try again or believe me when I was basically telling him he missed with the first injection.
 
OOF
6 days ago  
Is it safe?
 
6 days ago  
A man goes to the doctor for a prostate exam, but is worried that it will hurt. The doctor says "want me to numb it up for you?" and the man says "yes, please."

Then the doctor sticks his face in the man's butt and goes "num num num"
 
6 days ago  

HailRobonia: A man goes to the doctor for a prostate exam, but is worried that it will hurt. The doctor says "want me to numb it up for you?" and the man says "yes, please."

Then the doctor sticks his face in the man's butt and goes "num num num"


Thread's over.
 
6 days ago  
You know what's fun?  Discovering you're immune to local at the beginning of a vasectomy.

/Uh, no we're not going to continue, thank you very much.
//Knock me the fark out.
///Didn't want to be awake for it anyway
////super glad I live where this covered by socialist health care.
 
6 days ago  
www.chud.com
 
6 days ago  
Articaine is an amazing anesthetic. Any patient that states they have trouble getting numb gets a cartridge of Articaine. No problem.
 
6 days ago  

OOF: Is it safe?


Is what safe?...

While I'm not immune to it, I have a very high tolerance for it. Drives my dentist nuts, the amount of novocaine he uses on me.
 
6 days ago  
Genetic mutation?  I like to think of it as a "Super Power"

The man who felt noall pain, as it were.
 
6 days ago  

Rihlsul: You know what's fun?  Discovering you're immune to local at the beginning of a vasectomy.

/Uh, no we're not going to continue, thank you very much.
//Knock me the fark out.
///Didn't want to be awake for it anyway
////super glad I live where this covered by socialist health care.


Same here. I was good up until he cut the first vas. I felt that. Completely.
 
6 days ago  

Silverstaff: For ~25 years I thought dental anaesthetics had no effect on me.

As a kid, back around 1991 I had to have a filling in one tooth.  The anaesthetic numbed my mouth and I was talking funny. . .but I felt EVERYTHING when the dentist drilled me.  He wouldn't believe that I could feel everything and was shouting at me to stop screaming.  It was very, VERY unpleasant and rather mentally scarring to be forcibly held down by the hygenist while the dentist drills, feeling everything the whole way.

It left me with a life-long fear of dentists and dental work.

I finally went to a dentist last month.  The only other dental work I'd had in my whole life was having my wisdom teeth cut out (because the Army required it), and they knocked me out for that one.  I looked up a dentist that would do sedation dentistry, since I thought I was apparently immune to novocaine and would need to be knocked out to do anything to me.

They did a little test.  Nope, not immune.  They were able to do all the dental work I really, really needed with just a local, and I feel a helluva lot better afterwards.  It turns out that small-town dentist was just really incompetent and didn't numb the right part of my mouth, and refused to try again or believe me when I was basically telling him he missed with the first injection.


I keep telling my dentists that it never works and that I can feel everything. They keep saying that I'm lying and to stop pretending that I can feel the pain..

One dentist even injected me 3 times in one go, didn't work. Bastard had the cheek to charge me for the 3 injections at £50 a pop. And that was 30 years ago..
 
6 days ago  
Old news. Redheads have this issue

/num num
 
6 days ago  
img.fark.net
 
6 days ago  
Cold?
 
6 days ago  

Silverstaff: For ~25 years I thought dental anaesthetics had no effect on me.

As a kid, back around 1991 I had to have a filling in one tooth.  The anaesthetic numbed my mouth and I was talking funny. . .but I felt EVERYTHING when the dentist drilled me.  He wouldn't believe that I could feel everything and was shouting at me to stop screaming.  It was very, VERY unpleasant and rather mentally scarring to be forcibly held down by the hygenist while the dentist drills, feeling everything the whole way.

It left me with a life-long fear of dentists and dental work.

I finally went to a dentist last month.  The only other dental work I'd had in my whole life was having my wisdom teeth cut out (because the Army required it), and they knocked me out for that one.  I looked up a dentist that would do sedation dentistry, since I thought I was apparently immune to novocaine and would need to be knocked out to do anything to me.

They did a little test.  Nope, not immune.  They were able to do all the dental work I really, really needed with just a local, and I feel a helluva lot better afterwards.  It turns out that small-town dentist was just really incompetent and didn't numb the right part of my mouth, and refused to try again or believe me when I was basically telling him he missed with the first injection.


I had the same happen as well. Incompetent family dentist that was also a family friend. Had multiple procedures where I wasn't numb enough, explained with "well, it doesn't work for some people".

Dumbfark also "fixed" two metal fillings by surrounding them with the resin, rather than drilling out the old filling and putting a new one in. Ended up needing root canals for those teeth. Following dentist said that he's never seen something like that.
 
6 days ago  
The first dentist that I liked listened to me when I said I usually feel pain when I have work done. She did a cold swab that tests if you have been numbed properly by pressing a small bit of cloth soaked in a chemical that feels cold when it's pressed against a tooth. She would use that and hit me with more novocain until I couldn't feel the swab. it took her a few tries, but it was the first time I felt at ease with a dentist.
 
6 days ago  
It's not just locals.  Imagine the joy of learning you're immune to Versed during a spinal procedure.
 
6 days ago  
My dentist is not the least bit stingy with the gas. Getting a single filling? Gas me. I rather dislike dental work, but the gas at least makes it bearable.
 
Ant
6 days ago  

OOF: Is it safe?


Is it secret?
 
6 days ago  

MythDragon: My dentist is not the least bit stingy with the gas. Getting a single filling? Gas me. I rather dislike dental work, but the gas at least makes it bearable.


Huh. The gas is the one thing that has yet to have an effect on me. I've asked them plenty of times to "turn up the juice" but, they say that they can't do it. It doesn't even take the edge off of me. I, too had a couple of bad experiences with dental work as a kid and I have an anxiety attack every time I have to go.
 
6 days ago  
Novocaine wears off super fast at the dentist and ive had problems with morphine being ineffective when ive gone to the ER but dilaudid seems to work great.

really great.

really really great.
 
6 days ago  

dragonchild: Cold?


For me, yes. It's like a pin point laser beam of cold right at my tooth.

My last filling, the doctor completely numbed the main nerve to my jaw in the back of my mouth. It did the trick and we were able to pull through it without issue.
 
6 days ago  

RJReves: [www.chud.com image 500x284]


You're singing my tune.
 
6 days ago  
I have been terrified of dentists my whole life.  Parents took me to a pediatric dentist.  While I'm sure he was a nice guy, I had paroxysms because they wouldn't let family members be nearby while he worked.  It wouldn't have been so bad except the dentist was so casual about it.  He made lighthearted quips and spoke in this lilting voice I can still remember today.  I'm sure he was only trying to be reassuring, but it just made me feel worse, like he thought the whole thing was a lark.  Hey, I was like eight years old.  What the Fark did I know.

It's probably the law somewhere, because I couldn't have a family member nearby either during wisdom teeth surgery.  Except that time I was asking the surgeon questions about the surgery, and he finally said real snotty tome, What's your bottom line here?  Get to the point.

I flipped my shiat and refused to let them touch me.  That's one benefit of being an adult.  If you decide you don't want a procedure done, they aren't going to goddamn force you.  Just farking try it.  I could use the lawsuit money.  >:/

Still haven't had the wisdom teeth pulled, but in the spirit of adulting, I accept that I could have done something a long time ago and didn't, should my teeth go awry because of it.

Yay adulting.
 
6 days ago  

Silverstaff: For ~25 years I thought dental anaesthetics had no effect on me.

As a kid, back around 1991 I had to have a filling in one tooth.  The anaesthetic numbed my mouth and I was talking funny. . .but I felt EVERYTHING when the dentist drilled me.  He wouldn't believe that I could feel everything and was shouting at me to stop screaming.  It was very, VERY unpleasant and rather mentally scarring to be forcibly held down by the hygenist while the dentist drills, feeling everything the whole way.

It left me with a life-long fear of dentists and dental work.

I finally went to a dentist last month.  The only other dental work I'd had in my whole life was having my wisdom teeth cut out (because the Army required it), and they knocked me out for that one.  I looked up a dentist that would do sedation dentistry, since I thought I was apparently immune to novocaine and would need to be knocked out to do anything to me.

They did a little test.  Nope, not immune.  They were able to do all the dental work I really, really needed with just a local, and I feel a helluva lot better afterwards.  It turns out that small-town dentist was just really incompetent and didn't numb the right part of my mouth, and refused to try again or believe me when I was basically telling him he missed with the first injection.


I think I am immune to novacaine.  My dad is as well and we both had different dentists (I have actually had a couple and I could never get numbed) so it is a genetic thing (thanks dad!).

It has left me with crippling anxiety for dentistry.  Even a normal checkup/cleaning I will get anxious.  I went to the dentist for the first time in about 2 years on Monday and I need some cavities drilled, crowns, and a gingivitis treatment.   Due to my insurance I can only get the treatment and the cavities taken care of this year and next year will have to get the crowns.  I will only get sedation treatment now.

I also had braces (and have a permanent bottom retainer) so that doubled the fun!  Before the braces I had a tooth coming down through the gums above another one and another hole in my gums where you could see an impacted tooth, a major overbite and crossed incisors.
 
6 days ago  
Geeze subs thanks for the imagery.
 
6 days ago  
Ligajet.  Works for me.
 
6 days ago  

Silverstaff: For ~25 years I thought dental anaesthetics had no effect on me.

...since I thought I was apparently immune to novocaine and would need to be knocked out to do anything to me.


The anesthetic they are using now is different. Novocaine was used more in the past and it's probable that Novocaine is ineffective for you but Lidocaine does work. I think most dentists transitioned to lidocaine based injections a decade ago. I haven't seen Novocaine used for a long time and the newer injections seem to work better for me.

And if your parents let you have an aspirin and a soda that might have changed how the anesthetic worked for you. For many people (myself included) the combination of aspirin (possibly other NSAIDs) and caffeine can nearly completely block the effectiveness of local anesthetics. I learned that after having aspirin and coffee before going to the dentist as an adult.

Also I have some red hair genetics in my background which means a lot of anesthetics may lack punch. I kind of wonder what the heck my ancestors were eating to make that a useful gene.
 
6 days ago  
It works for me, but it takes an unusually long time to kick in.
They really ought to let me go and read a magazine or something for awhile after the injection.
 
6 days ago  

Burr: Silverstaff: For ~25 years I thought dental anaesthetics had no effect on me.

As a kid, back around 1991 I had to have a filling in one tooth.  The anaesthetic numbed my mouth and I was talking funny. . .but I felt EVERYTHING when the dentist drilled me.  He wouldn't believe that I could feel everything and was shouting at me to stop screaming.  It was very, VERY unpleasant and rather mentally scarring to be forcibly held down by the hygenist while the dentist drills, feeling everything the whole way.

It left me with a life-long fear of dentists and dental work.

I finally went to a dentist last month.  The only other dental work I'd had in my whole life was having my wisdom teeth cut out (because the Army required it), and they knocked me out for that one.  I looked up a dentist that would do sedation dentistry, since I thought I was apparently immune to novocaine and would need to be knocked out to do anything to me.

They did a little test.  Nope, not immune.  They were able to do all the dental work I really, really needed with just a local, and I feel a helluva lot better afterwards.  It turns out that small-town dentist was just really incompetent and didn't numb the right part of my mouth, and refused to try again or believe me when I was basically telling him he missed with the first injection.

I think I am immune to novacaine.  My dad is as well and we both had different dentists (I have actually had a couple and I could never get numbed) so it is a genetic thing (thanks dad!).

It has left me with crippling anxiety for dentistry.  Even a normal checkup/cleaning I will get anxious.  I went to the dentist for the first time in about 2 years on Monday and I need some cavities drilled, crowns, and a gingivitis treatment.   Due to my insurance I can only get the treatment and the cavities taken care of this year and next year will have to get the crowns.  I will only get sedation treatment now.

I also had braces (and have a permanent bottom retainer) so tha ...


ive woken up with the dentists knee being used for leverage on the armrest as they try yanking a wisdom tooth out which they had already split with a chisel.

and i was told i am at the maximum dose based on my weight and the tooth was halfway out so just gimme a couple more minutes....
 
6 days ago  

garandman1a: OOF: Is it safe?

Is what safe?...

While I'm not immune to it, I have a very high tolerance for it. Drives my dentist nuts, the amount of novocaine he uses on me.


I have an extremely high tolerance as well. I've had a handful of dentist's tell me that they couldn't by law give me anymore, and I just tell them to go ahead, and I go to my happy place while I feel EVERYTHING.
 
6 days ago  

The Lurker at Your Threshold: RJReves: [www.chud.com image 500x284]

You're singing my tune.


Enjoyed the original movie
Really loved the musical remake
Saw a stage production, way the Fark off Broadway. Quite enjoyable. Audrey 2 was rather cheesy..
 
6 days ago  
I'll take a filling any day rather than a clotted hemmorrhoid excision. Thankfully local anesthetics are functional for me but there's still like a shadow of the feeling for either procedure and the shadow of the feeling of jellied blood getting squeezed out of a venous balloon in the ass is somehow much worse than the pressure and buzz of a drill in the tooth.

Some days plants and fungi are lucky for their lack of a nervous system from an animals perspective.
 
6 days ago  

A Vain Tangent: I'll take a filling any day rather than a clotted hemmorrhoid excision. Thankfully local anesthetics are functional for me but there's still like a shadow of the feeling for either procedure and the shadow of the feeling of jellied blood getting squeezed out of a venous balloon in the ass is somehow much worse than the pressure and buzz of a drill in the tooth.

Some days plants and fungi are lucky for their lack of a nervous system from an animals perspective.


img.fark.net
 
6 days ago  
When I was a kid, I had 7 teeth pulled.  One tooth a week for 7 weeks.  By the last tooth, the novocaine had no effect, I guess I became tolerant.  They ended up giving me 4 shots, but nothing, so they said fark it and just yanked with the pliers and I felt everything.  It was a permanent molar, so that thing was in there good.  Took a whole lot of twisting and yanking to get it out.  Dentists are sadists.
 
6 days ago  
I have never had an anesthetic for a filling. Are your dentists incompetent or don't they deal with cavities until they hit the nerve or something?
 
6 days ago  
You Americans are big Pussies. In Soviet Russia we did not use no anesthetics on teeth drilling! And the drill was so large that when the comrade dentist drilled -- it sounded like a jackhammer. And painful. And when I (then a nine-year-old kid) raised hands in pain, the dental torturer was screaming, "PUT YOUR HANDS DOWN! OR ELSE I'LL DRILL THROUGH YOUR TONGE!" My parents made me visit dentist rather frequently, and in that big room there were many procedures going on at once. But I never seen them tie anyone hands down on anyone, even when they were pulling teeth. They scare you in submission.
 
6 days ago  

DerAppie: I have never had an anesthetic for a filling.

img.fark.net

 
6 days ago  
I'm fortunate my only major dental surgery was for my wisdom teeth. The general anesthetic they gave me knocked me out almost immediately. I vaguely remember the assistant counting down from ten and then waking up an hour or so later confused where I was.
 
6 days ago  

Bluemoons: garandman1a: OOF: Is it safe?

Is what safe?...

While I'm not immune to it, I have a very high tolerance for it. Drives my dentist nuts, the amount of novocaine he uses on me.

I have an extremely high tolerance as well. I've had a handful of dentist's tell me that they couldn't by law give me anymore, and I just tell them to go ahead, and I go to my happy place while I feel EVERYTHING.


I got in the habit of digging my fingernail into my thumb while getting drilled, just something to take my mind off of the pain.

/the smell of burning bone still haunts me.
 
6 days ago  

Eli WhiskeyDik: MythDragon: My dentist is not the least bit stingy with the gas. Getting a single filling? Gas me. I rather dislike dental work, but the gas at least makes it bearable.

Huh. The gas is the one thing that has yet to have an effect on me. I've asked them plenty of times to "turn up the juice" but, they say that they can't do it. It doesn't even take the edge off of me. I, too had a couple of bad experiences with dental work as a kid and I have an anxiety attack every time I have to go.


You have to breath it in through your nose or it won't work. Maybe they are just giving you only oxy? It should have a peculiar smell to it.

You want anxiety? Try going to a dentist just across from a Firestone when you're young and have them fire up the impact wrench just as you go in. *WRRRRRRRRR CHAKCHAKCHAKCHAK WRRRRRRRRR* "AAAAAAAGH what the hell is that?"
 
6 days ago  

Silverstaff: For ~25 years I thought dental anaesthetics had no effect on me....


Reminds me of my childhood dentist (now retired).  I had many cavities/fillings growing up.  I was never afraid of the dentist, but I definitely got used to it hurting quite a bit (even with anesthetic).  There were several times where I'd raise my hand to indicate pain and I was told "oh, I'm almost done" and had to suck it up for the rest.

Fast forward to recent years when I've had to get a root canal and other work.  I mentioned to the doc as he was about to inject me that I recall things being painful in the past.  He decided to test prior to starting the drilling.  It hurt, so we waited a couple extra minutes.  Surprise, no pain at all.  (Also found out I had 5 roots in the one tooth, so I'm a mutant.)
 
6 days ago  
How I feel about dentists
 
6 days ago  

Eli WhiskeyDik: [img.fark.net image 223x226]


For many years now whenever I have a dental procedure which requires anesthesia of any kind I ask them to give me the short duration stuff. I find the numbness far more annoying than the dull ache of the procedure. It usually wears off in about 1-2 hours at most. OTC meds take care of any pain.

You should be able to ask for it.
 
6 days ago  
I always thought that my dentist was just a cheap bastard that watered down the anesthetic. I bit the old SOB more then once.
 
6 days ago  
I hate dentists. Was way sick as a kid. All my teeth are crap from antibiotics damaging the enamel.

Really looking forward to this http://www.sciencealert.com/this-new-drug-can-regenerate-teeth-possibl​y-reducing-the-need-for-man-made-fillings
 
6 days ago  

MythDragon: Eli WhiskeyDik: MythDragon: My dentist is not the least bit stingy with the gas. Getting a single filling? Gas me. I rather dislike dental work, but the gas at least makes it bearable.

Huh. The gas is the one thing that has yet to have an effect on me. I've asked them plenty of times to "turn up the juice" but, they say that they can't do it. It doesn't even take the edge off of me. I, too had a couple of bad experiences with dental work as a kid and I have an anxiety attack every time I have to go.

You have to breath it in through your nose or it won't work. Maybe they are just giving you only oxy? It should have a peculiar smell to it.

You want anxiety? Try going to a dentist just across from a Firestone when you're young and have them fire up the impact wrench just as you go in. *WRRRRRRRRR CHAKCHAKCHAKCHAK WRRRRRRRRR* "AAAAAAAGH what the hell is that?"


Yes, it does come in through the nose. The apparatus that they put on my only goes over the nose.
I larfed at the Firestone story. That would have sent me running and screaming out of that dentist office.
 
6 days ago  
I'm about to get a tooth pulled in a week (was hoping for just a root canal, but the tooth has a crack running down the length of it on the inside), so I'm getting a kick out of this...

/Good thing I can't feel it
//Drinking coffee after dentalwork is weird
///I can only feel the slashies on one side of my face
 
6 days ago  

OdradekRex: It's not just locals.  Imagine the joy of learning you're immune to Versed during a spinal procedure.


I guess after getting a few more shots of it, you know how much it takes. You could say you're well-versed in it.
 
6 days ago  

Giltric: Burr: Silverstaff: For ~25 years I thought dental anaesthetics had no effect on me.

As a kid, back around 1991 I had to have a filling in one tooth.  The anaesthetic numbed my mouth and I was talking funny. . .but I felt EVERYTHING when the dentist drilled me.  He wouldn't believe that I could feel everything and was shouting at me to stop screaming.  It was very, VERY unpleasant and rather mentally scarring to be forcibly held down by the hygenist while the dentist drills, feeling everything the whole way.

It left me with a life-long fear of dentists and dental work.

I finally went to a dentist last month.  The only other dental work I'd had in my whole life was having my wisdom teeth cut out (because the Army required it), and they knocked me out for that one.  I looked up a dentist that would do sedation dentistry, since I thought I was apparently immune to novocaine and would need to be knocked out to do anything to me.

They did a little test.  Nope, not immune.  They were able to do all the dental work I really, really needed with just a local, and I feel a helluva lot better afterwards.  It turns out that small-town dentist was just really incompetent and didn't numb the right part of my mouth, and refused to try again or believe me when I was basically telling him he missed with the first injection.

I think I am immune to novacaine.  My dad is as well and we both had different dentists (I have actually had a couple and I could never get numbed) so it is a genetic thing (thanks dad!).

It has left me with crippling anxiety for dentistry.  Even a normal checkup/cleaning I will get anxious.  I went to the dentist for the first time in about 2 years on Monday and I need some cavities drilled, crowns, and a gingivitis treatment.   Due to my insurance I can only get the treatment and the cavities taken care of this year and next year will have to get the crowns.  I will only get sedation treatment now.

I also had braces (and have a permanent bottom retainer) so tha ...

ive woken up with the dentists knee being used for leverage on the armrest as they try yanking a wisdom tooth out which they had already split with a chisel.

and i was told i am at the maximum dose based on my weight and the tooth was halfway out so just gimme a couple more minutes....


When I was 20 I had a wisdom tooth chiseled out with only shots in the gum.  It didnt hurt much but the pressure of the dentist banging on my tooth was unreal.  That experience put me off dentists for 20 years unfortunately.

I finally went back after cracking a tooth on a chicken bone.  I ended up getting 4 crowns over the span of a month and one filling.  Local shots only for anesthetic.  Five hours awake in the chair while they prepped the teeth for the crowns.  Im lucky after all those years that was all they had to do.

The new dentist is a really nice woman with good bedside manner.  Everyone in that office is pretty awesome.  Will not be neglecting oral health ever again.

/Ill take the shots over gas as I fortunately respond well to them.
//dental tech has really come a long way. I think the crowns were 3D printed at the lab.
 
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