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(Lexington Herald Leader)   Ebola serum's secret ingredient: Kentucky tobacco   (kentucky.com) divider line 56
    More: Followup  
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5408 clicks; posted to Main » on 05 Aug 2014 at 10:10 AM (19 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2014-08-05 09:02:28 AM  
I'll bet a nice burly or latakia would give the HIV a run for its money...
 
2014-08-05 09:33:58 AM  
In a study published last year, scientists at the U.S. Army Medical Research Institute of Infectious Diseases reported that 43 percent of infected nonhuman primates recovered after receiving the treatment intravenously 104 to 120 hours after infection - after symptoms developed.

I'm a bit curious what that actually means. What's the typical death rate? 43% is barely better than the 60% survival rate currently reported on Ebola Zaire. Obviously latent symptoms are a bad sign.
 
2014-08-05 10:13:05 AM  
The nicotine content of my blood must make me immune then.
 
2014-08-05 10:15:15 AM  
Anytime they're giving a "compound" a code name that starts or ends with "Z", I start to get worried.
 
2014-08-05 10:17:51 AM  
img.fark.net

Let's see all natural organically grown homeopathic lettuce do that.
 
2014-08-05 10:17:58 AM  
This is kind of cool.  Much like getting certain variants of e. coli to replicate human insulin.
http://www.madehow.com/Volume-7/Insulin.html
 
2014-08-05 10:18:02 AM  
Simpsons did it.

1.bp.blogspot.com
 
2014-08-05 10:18:23 AM  
1.bp.blogspot.com
 
2014-08-05 10:19:25 AM  

bdub77: In a study published last year, scientists at the U.S. Army Medical Research Institute of Infectious Diseases reported that 43 percent of infected nonhuman primates recovered after receiving the treatment intravenously 104 to 120 hours after infection - after symptoms developed.

I'm a bit curious what that actually means. What's the typical death rate? 43% is barely better than the 60% survival rate currently reported on Ebola Zaire. Obviously latent symptoms are a bad sign.


Historical survival rate is 10%, current outbreak is 40%. 43% is a small improvement, but it's at least a start.

If the alternative was bleeding to death out my nose/eyeballs/ass, I'd take an injection of damn near anything for a 3% better chance.
 
2014-08-05 10:20:08 AM  

hardinparamedic: [img.fark.net image 500x341]

Let's see all natural organically grown homeopathic lettuce do that.


WHAT THE ACTUAL HELL, I thought I'd misclicked onto Tumblr for a moment. Hi, want to be my best friend?
 
2014-08-05 10:20:51 AM  
Well, ain't that somethin' said the tomato to the nicotine
 
2014-08-05 10:21:18 AM  

RainbeauxSue: bdub77: In a study published last year, scientists at the U.S. Army Medical Research Institute of Infectious Diseases reported that 43 percent of infected nonhuman primates recovered after receiving the treatment intravenously 104 to 120 hours after infection - after symptoms developed.

I'm a bit curious what that actually means. What's the typical death rate? 43% is barely better than the 60% survival rate currently reported on Ebola Zaire. Obviously latent symptoms are a bad sign.

Historical survival rate is 10%, current outbreak is 40%. 43% is a small improvement, but it's at least a start.

If the alternative was bleeding to death out my nose/eyeballs/ass, I'd take an injection of damn near anything for a 3% better chance.


I don't have the information but the 104-120 hours could be a shorter time period of being sick then without the medicine.  That would also be a good thing.
 
2014-08-05 10:22:09 AM  
Thanks, big tobacco.  You're the best.
 
2014-08-05 10:23:22 AM  
FTA:  "Scientists have long known that tobacco readily picks up genes inserted into it."

Interesting...be nice if all those tobacco farmers could find new uses for their product.

/not opposed to smokers
//except the ones who leave their butts everywhere
 
2014-08-05 10:24:02 AM  
Way to go, Colonel!!

img.fark.net
 
2014-08-05 10:24:10 AM  

bdub77: I'm a bit curious what that actually means. What's the typical death rate? 43% is barely better than the 60% survival rate currently reported on Ebola Zaire. Obviously latent symptoms are a bad sign.


http://stm.sciencemag.org/content/5/199/199ra113

Looks like Rhesus are universally susceptible.  This study falls on the heals of an initial study where they treated shortly after exposure and had 100% recovery.
 
2014-08-05 10:24:17 AM  
Krusty brand children's cough syrup cures SARS.
 
2014-08-05 10:27:39 AM  
DDT cures crabs and head lice
 
2014-08-05 10:29:55 AM  

GMO's!!! GMO's!!! GMO's!!!

 
2014-08-05 10:30:12 AM  
This here tobacco will cure anything you got:

http://www.nytimes.com/2013/05/05/us/tobacco-lovers-discover-mystiqu e- of-perique.html?_r=0

Every cigarette you smoke adds twelve minutes to your life.

www.cigarettespedia.com

If you don't smoke, you can drink it.

img.fark.net
 
2014-08-05 10:32:06 AM  
They'll find a cheaper way to produce it using mushrooms or other fungi. The tobacco farmers will go back to prepping for federally legal weed.
 
2014-08-05 10:33:08 AM  

drjekel_mrhyde: DDT cures crabs and head lice


Agent Orange cures headaches.
 
2014-08-05 10:35:56 AM  
PunGent:

/not opposed to smokers
//except the ones who leave their butts everywhere


I apologize.  Here, let me just leave this here.
encrypted-tbn0.gstatic.com
 
2014-08-05 10:38:06 AM  

El Dudereno: drjekel_mrhyde: DDT cures crabs and head lice

Agent Orange cures headaches.


So does a guillotine.
 
2014-08-05 10:39:48 AM  
img.fark.net
 
2014-08-05 10:43:46 AM  

MooseBayou: PunGent:

/not opposed to smokers
//except the ones who leave their butts everywhere

I apologize.  Here, let me just leave this here.
[encrypted-tbn0.gstatic.com image 194x260]


img.fark.net

Let me expand on that.
 
2014-08-05 10:43:58 AM  
No Ebola for me! Hack hack hack hack cough wheeeeeeeeeze. Clears throat. Anyone know where I can spit this honker?
 
2014-08-05 10:47:03 AM  

PunGent: FTA:  "Scientists have long known that tobacco readily picks up genes inserted into it."

Interesting...be nice if all those tobacco farmers could find new uses for their product.

/not opposed to smokers
//except the ones who leave their butts everywhere


This and I am a smoker leaving butts everywhere is just lazy
 
2014-08-05 10:58:37 AM  
Tobacco cures Ebola and thus all smoking bans are hereby revoked. Checkmate, libtards!
 
2014-08-05 11:04:48 AM  

mediablitz: GMO's!!! GMO's!!! GMO's!!!


No Ebola treatments for Europe then, I guess. So sorry, old chaps.
 
2014-08-05 11:15:21 AM  

Tax Boy: [1.bp.blogspot.com image 528x400]


man...21 seconds.
 
2014-08-05 11:16:40 AM  
Reminds me of X-Files episode where one guy survived an epidemic because he smoked.
 
2014-08-05 11:19:32 AM  

LazyMedia: Tobacco cures Ebola and thus all smoking bans are hereby revoked. Checkmate, libtards!


You forgot that Sarah Palin automatically becomes President.
 
2014-08-05 11:20:35 AM  

BitwiseShift: They'll find a cheaper way to produce it using mushrooms or other fungi. The tobacco farmers will go back to prepping for federally legal weed.



With 50% of the adults in China smoking, I don't think the tobacco farmers are hurting for a market.

But yeah, I'd rather see them growing cannabis; either the smoking kind, or oil and fiber hemp varieties.
 
2014-08-05 11:26:02 AM  
Joe Camel cured ebola?!

i1182.photobucket.com
 
2014-08-05 11:29:54 AM  

give me doughnuts: With 50% of the adults in China smoking, I don't think the tobacco farmers are hurting for a market.


As if the air wasn't bad enough already.
 
2014-08-05 11:31:31 AM  
I bet that it's before they add all those chemicals they put in for smokers.

imageshack.com

You know that is a pair of "tightly packed" jeans.
/Wonders if it would be as nice without the jeans.
 
2014-08-05 11:43:11 AM  
Well, this is actually pretty interesting.  Something vilified as totally useless and evil and deadly and wicked and bad can be useful and possibly modified to be quite helpful and beneficial?  I think I'm going to be forwarding this to a few losers I know, just to watch them froth at the mouth.  I don't smoke, but really don't care if you do.  Please just don't be a pig about it.
 
2014-08-05 11:58:35 AM  

Farce-Side: Thanks, big tobacco.  You're the best.


Except for the part where they started the epidemic in the first place to improve international demand for their product, which has fallen out of favor in this country...
 
2014-08-05 12:00:28 PM  
Sorry, just checked the comments to see if that was a euphemism.
 
2014-08-05 12:01:50 PM  

MooseBayou: PunGent:

/not opposed to smokers
//except the ones who leave their butts everywhere

I apologize.  Here, let me just leave this here.
[encrypted-tbn0.gstatic.com image 194x260]


Completely acceptable :)
 
2014-08-05 12:11:54 PM  

bdub77: In a study published last year, scientists at the U.S. Army Medical Research Institute of Infectious Diseases reported that 43 percent of infected nonhuman primates recovered after receiving the treatment intravenously 104 to 120 hours after infection - after symptoms developed.

I'm a bit curious what that actually means. What's the typical death rate? 43% is barely better than the 60% survival rate currently reported on Ebola Zaire. Obviously latent symptoms are a bad sign.


These are primate studies, and the monkeys are given huge infectious doses of Ebola virus.  Mortality is nearly 100% under these conditions.  43% survival is actually a big improvement.
 
2014-08-05 12:35:08 PM  
The good news is it cures Ebola

/The bad news is it causes Cancer
 
2014-08-05 12:46:15 PM  

RainbeauxSue: Historical survival rate is 10%, current outbreak is 40%. 43% is a small improvement, but it's at least a start.


The way they are currently calculating survival rate is the sum of the probable ebola cases + definitive ebola cases as the denominator.  Thus non-ebola cases with similar clinical presentation (e.g. malaria, typhoid fever, dengue fever, chickengunya, etc...) but naturally reduced mortality are in the mix.  If you counted only confirmed ebola cases (they are using PCR methods, apparently) I bet the mortality rate would be much higher than 45% (or the 55% I read in the WSJ yesterday).

Source: physician from Monrovia working at JFK Hospital.

themoreyouknow.jpg

- bs
 
2014-08-05 01:07:06 PM  
Maureen McDonnell knew she was on to something big!
 
2014-08-05 01:11:45 PM  

Stoker: You know that is a pair of "tightly packed" jeans.
/Wonders if it would be as nice without the jeans.


Top pic here is without jeans and so slightly nsfw perhaps by fark standards
 
2014-08-05 01:14:10 PM  
I said this in the other thread but multiple bears, etc:

Having the choice between ebola with no treatment or being the first test subject for a new monoclonal antibody is a very difficult choice. I would be seriously tempted to take my chances with ebola alone.

Monoclonal antibodies are extraordinarily dangerous because they are playing around with the low level operations of the human immune system. These sorts of antibodies cannot be successfully tested for safety in animals. The most famous example is TGN1412, an antibody superagonist that caused a cytokine storm in the first 6 test subjects, causing their heads to swell up "like the elephant man" and multiple organ failure only hours after administration. It was administered at 1/500th of the dose found safe in animals.

The warnings on FDA approved monoclonal antibodies often include "sudden death within 24 hours of administration." And these are the MABs that made it through human trials.

I'm glad this worked out for the two Americans, but make no mistake: this was a friggin coin toss with their lives. There was the very real possibility that an untested monoclonal antibody could have killed them faster than the ebola, or that the drug could have crippled their immune systems due to some unforeseen and untestable interaction with the human immune system.
 
2014-08-05 01:15:25 PM  

Stoker: Wonders if it would be as nice without the jeans.


Look at the rest of her. It'd be better without those jeans. sitting on your face.
 
2014-08-05 01:20:47 PM  
Product placement.
 
2014-08-05 01:46:59 PM  

cs30109: bdub77: In a study published last year, scientists at the U.S. Army Medical Research Institute of Infectious Diseases reported that 43 percent of infected nonhuman primates recovered after receiving the treatment intravenously 104 to 120 hours after infection - after symptoms developed.

I'm a bit curious what that actually means. What's the typical death rate? 43% is barely better than the 60% survival rate currently reported on Ebola Zaire. Obviously latent symptoms are a bad sign.

These are primate studies, and the monkeys are given huge infectious doses of Ebola virus.  Mortality is nearly 100% under these conditions.  43% survival is actually a big improvement.


Looking at the study itself: all controls died within 10 days.
img.fark.net
 
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