Do you have adblock enabled?
If you can read this, either the style sheet didn't load or you have an older browser that doesn't support style sheets. Try clearing your browser cache and refreshing the page.

(NBC News)   Human albino gene found in dogs. Well, he always did like to spend time in his lab   (nbcnews.com) divider line 31
    More: Interesting, albino  
•       •       •

2454 clicks; posted to Main » on 20 May 2014 at 12:33 PM (50 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



31 Comments   (+0 »)
   
View Voting Results: Smartest and Funniest
 
2014-05-20 11:02:49 AM  
some1cur
 
2014-05-20 11:04:09 AM  
Does it make them evil as well?

www.albinism.org www.albinism.org

img.photobucket.com
 
2014-05-20 12:14:53 PM  
www.ithadtobeyou.net

Approves
 
2014-05-20 12:33:29 PM  
+1, subby
 
2014-05-20 12:34:56 PM  
Your dog wants sun glasses and a broad-rimmed hat.
 
2014-05-20 12:36:05 PM  
"What we found was a significant increase in risk for development of melanoma-like tumors in the albino dogs."

media3.s-nbcnews.com

Next up. How long does a human body burn in a furnace.
 
2014-05-20 12:38:34 PM  
Two paws up Subby!
 
2014-05-20 12:41:12 PM  

Because People in power are Stupid: Does it make them evil as well?


you left out:    2.bp.blogspot.com

and those freaky twins with dreadlocks in the Matrix film that should not have happened.
 
d23 [TotalFark]
2014-05-20 12:50:23 PM  
"See, I told you it would happen."

www.nashvillescene.com
 
2014-05-20 12:51:04 PM  

Sofa King Smart: and those freaky twins with dreadlocks in the Matrix film that should not have happened.


I actually liked them. They were new and interesting characters at least. Those two and Monica Bellucci were the only two watchable parts of that entire crapshow.
 
2014-05-20 12:53:12 PM  

Langston: Monica Bellucci were the only two watchable parts

 
2014-05-20 12:58:39 PM  
Yeah, that's not a human gene found in dogs, that's a mutation in a dog gene that is similar to a mutation in an equivalent human gene.
 
2014-05-20 01:00:21 PM  
/But +1 for the headline subby. Classy.
 
2014-05-20 01:00:45 PM  
i.imgflip.com
 
2014-05-20 01:00:47 PM  
Masseth?
 
2014-05-20 01:02:11 PM  
Mans best lay.
 
2014-05-20 01:22:45 PM  
img2.wikia.nocookie.net
 
2014-05-20 01:26:04 PM  
You'd be surprised how many of your genes you share with your dog. Or with mice (about 50%). Or even with bananas (25%). I suspect that American and Canadian poltiicians are mostly bananas.

Since the advent of genetics and gene replication on a large scale, scientists have been using mutations in genes shared by humans or shared with other species to not only track the movements of people in prehistory, but also to figure how how closely species are related to each other.

The gene clocks (such as the Y-chromosme and mitochondrial DNA) may run at different speeds, but the mutations do occur with regularity, which enables scientists to build a family tree for humans and for life in general.

I've been reading books genetics and genealogy lately, especially the British population, since they are covered in the most detail.

It is complicated and fascinating, but much has been and can be learned.

There is a lot of misunderstanding among the general public, however, of what all this means. This is particularly true of nationalists and racists. They think the genes can be used to support their favourite prejudices. Not so.

Take my Y-chromosome, please!

Oops! That is ruder than I intended.

But seriously, the Y chromosome is used to track the movement of men (through war, trade, slavery, etc.). All men have one, and only men have them. They have 17 genes, one of which turns a girl fetus into a boy fetus at six weeks after conception. That is all it does. The other 16 genes are largely involved with sperm production and quality. That is all they do.

But you can use the junk DNA (non-coding for proteins and apparently largely used only for spacers in the gene code) to track the ancestry of men.

All men have a lineage consisting solely of men--their father, paternal grand-father and so forth. All women have a lineage consisting solely of their Mother, their Mother's Mother and so forth. These two lineages are the only ones consisting entirely of one sex or the other. All the other of millions of ancestors you have are a mixture of daughters and sons.

The Y chromosome is thus a good clock to track men through history. But it is otherwise pretty much useless because the genes are so few and so vital that they scarcely change. It is only the junk that mutates much.

That said, a lot of racists and ignoramuses are making a big deal of where these mutated variants on a common theme come from. There is lose talk of "Jewish genes" and such. In Africa, many of my brothers by other mothers are using the haplotypes (groups of genes with the same mutations) to put down other nations and races, such as the Arabs or Black Africans, etc.) or as a badge of honour (We are so great! We are so great!)

That's not the way evolution works and it certainly isn't the way the Y chromosome works.

Every man has a Y chromosome (or two, sometimes even three, by a freak duplication that doesn't actually kill you but may have serious health or psychological effects). And they are essentially one and the same Y chromosome.

So don't think you are so great just because you have an R1b or an E1b 1b1 b1a or whatever.

R1b is the dominant Y in Western Europe, a couple of spots in Asia and one really odd spot in Africa. It is believed that there was a bit of reverse migration in the case of the African population. It is in Chad if I recall correctly.

E1b is very interesting because it is common only in Africa but is to be found in Europe and Western Asia. It almost disappears in East Asia and is not native anywhere else.

It has been called the "Jewish" Y chromosome but only 20% of Ashenazi Jews have it and between 8% and 30% of Shephardic Jews depending on country of origin.

The E haplogroups apparently mutated from a  D haplogroup in Ethiopia about 24,000 years ago. It reached the Middle East via Egypt. It is the only haplogroup outside of Africa that did not jump the Gate of Tears from Ethiopia into Arabia about 85,000 years ago. It is the last Y chromosome out of Africa.

All of the Y chromosomes that left Africa in our ancestors come from one of 12 haplogroups. Anthropologists have been divided Africans into five racial blocks, of which one gave rise to non-black Africans (non-African humans are a thumb among four African fingers) but now apparently, the variety in the African gene pool is much greater and the African gene pool is thus much older and deeper than we thought.

We are practically cloning out here. I'd say something about Asians all looking alike, but compared to a Hottentot, so do Europeans, if you are looking at the variety of their genes.

We have previously learned that a small troop of Chimpanzees have more gene variation than the whole human race, africans included. Well, that's because they are even older than modern humans. The difference between the most different humans is much smaller than difference between humans and apes at something like 8 to 50 mutations or something like that. I don't recall.

So genetics can tell us a lot about genealogy, but they can't tell us who is best. There is no best in Y chromosomes. We are all sons of Adam--and Adam and his thousands of contemporaries have their own Adam deeper in the past. It is Adams all the way down, to paraphrase the old joke about the Earth riding on the back of a turtle.

This E1b chromosome is the one which my ancestor has. In fact, several of my ancestors have it, but only one could pass it down to me.. I can't be sure that I'm not adopted, or that one of my great grandmothers was raped or commited adultery, but it is very likely I have this one: E1b 1b1 and so on. One mutation doesn't mean the scientists rename the Y chromosome haplotype, and even a couple may pass because genes can mutate back to their original form from time to time, but I share a Y chromosome with Hitler, Einstein, Caravaggio, the Wright Brothers and 20% of the Jews on average.

This chromosome is very interesting because the population where it originated seems to have invented agriculture on the way to the Sinai or after arriving in the fertile Cresecent. They carried agriculture into all parts of Africa, West and Central Asia and Europe from a base in Southern Turkey, Syria and the rest of the Fertile Crescent. Not only did they probably invent the pastoral lifestyle, but they invented farming generally, domesticated wheat, rye and barley, and probably played an oversized role in inventing several other elements of "Civilization" as we know it.

The question which interests me and many others is whether we get this gene from Jews, from Phoenecians, from Greeks or Macedonians, and when. You see, the few pockets of E1b and its sons in Europe are in places where the Romans had forts or the Greeks, Phonecians, Jews and others mined for gold, iron, tin, copper, and so forth. They are places where whole nations traded ideas and technologies and luxury goods.

Am I the descendant of a Phoenecian who traded in British tin in the Bronze Age? Did my direct male ancestor invent iron working? Was he a Jew under the aegis of the Roman Empire and if so was he Sephardic (from the Mediterranean) or Ashkenazi (from the land route through the Balkans and the Great Plain of Northern Europe.

We know that one of my male ancestors settled in the North of France during the population expansion of the Great Medieval Warm Period but was he a Norman carrying the E1b 1b1b etc. chromosome acquired during Neolithic expansion of farming or was he a refugee from Spain or Germany?

This is a complicated story with no end, because the Y chromosome is particularly heavy on the Atlantic Coast (even in bits of Scotland). The only sure thing is that layers upon layers of immigrants, traders, refugees, soldiers, slaves and what not carried this gene to the places it can be found today and reinforced them in some places.

In Northern Wales, for example, the E1b genes represent as much as 30-40% of the men in a small region that once had a Roman fort and tradiing town. On the Isle of Anglesey, which had tin mines, it is not quite so densely packed, but it is still quite high for a European region. It is in this same area that another haplytype, called T, also from the Middle East and typical of Phoenecians from Lebanon, Cathage and the other colonies, managed to find its way into the DNA of one Thomas Jefferson's ancestors.

And it is very likely that another President with an African father inherited this gene, which is carried by the majority of the tribe that his Father belongs to.

Although it is called the Jewish chromosome, it is hardly that because most Jewish men don't have it while as much as 85% of more of Berbers, Tuaregs and Somalian men do.

Interestingly, I find, Timbuctoo, the great literate civilization in the Sahara, was built by men carrying this chromosome variant. It seems to be closely tied to many of the great civilizations and empires, probably because the men who carry it have been wanderers and farmers and builders. Without agriculture, no villages, without villages no settled life, without settled life no states, armies, taxes, arts and sciences.

Another interesting factoid:  many of the Jews that have this gene (remember it is only one in five) seem to be men who claim descent from Levi, the  tribe to which Aaron, Moses and the priests of the Temple in Jerusalem belonged.

Given the massive number of farmers, clergymen (Baptist, Quaker and others), refugees and nation-builders in my family tree, I sort of feel at home with the idea that I might be a descendant of Aaron. I have already found a 33rd Great grandfather who claimed descent from King David, and Lord help me, I have a ton of saints in my family tree, Roman Catholic and other, as well as the Herodian and Hasmonean dynasties (through Vandal and Roman ancestors.

But this has absolutely nothing to do with the Y chromosome. It makes you a man. It doesn't make you a Jew, a Muslim, a Christian or an atheist. It doesn't make you a refugee, a barbarian or a king. It doesn't make you a farmer even. It was a historical accident (in the philosophical sense of the word) that caused my entire male line to be tied to the rise of agriculture, empire, civilization and eventually, Canada and the United States. Because we DID build that, Mr. Obama. Welcome to the project. Put on your hard hat and follow us.

I wonder what Jefferson would have thought of that. After all, he is a famous Lebanese American with his Middle Eastern T haplotype chromosome. At least a couple of thousand years back, and up to 4,000 B.P. his ancestors helped to bring agriculture and trade even to remote Scotland, which was nearly the ends of the Earth in those days.
 
2014-05-20 01:35:36 PM  
Guffaw.
 
2014-05-20 01:35:38 PM  
 
2014-05-20 01:35:48 PM  
As for my Mother's mitochondrial DNA, I haven't a clue. Nobody seems to have taken the test in my Mother's maternal line, which goes back to England and 1582. She is likely an H haplotype. One of the geneticists who tested thousands of people in the UK named the H mitochondrial DNA group Helena.

Helena has been localized to Southern France during the Ice Age. The tundra ran down to the South of France, but the sea levels were lower. Helena lived in a group of hunter-gatherers taking refuge from the Ice on the shores of the Mederranean, which were as much as 50 miles out to sea from today's coast.

I hope to take the test some day and determine which Haplotype my female relations have. It is probably Helena because they account for over 50% of the English women in the region where my ancestress lived.

Unlike my paternal ancestor, she was part of the mainstream of Western Europeans, and she never saw North America. But she had two daughters at least and though she is probably buried under the Mediterannean Sea,these two daughters have descendants all over Europe and beyond. All of the Daughters of Eve have to have at least two daughters for their genes to be carried into the general population.
.

Like the Adams, it is Eves all the way down. Mitochondrial Eve is much older than Adam--or not perhaps. But she had an Eve in her past, and there are other Eves in our future. One of the current mitochondrial types will eventually outsurvive the others due to women having only sons or no children at all. And this new Eve will beget many daugheters, we may hope.

Evolution works, bi-atch! Let's hope politics, religion and culture can keep up!
 
2014-05-20 01:39:07 PM  

Starhawk: brantgoose: ...

[i.chzbgr.com image 500x333]


Hey, not everybody is a Twitter member!

I am just one of those unfortunate people who not only think in sentences but also paragraphs and chapters. Can't help that. Blame the Jews. Or the Tuaregs. Or the Muslims. They all have a love of books and learning, even in Wales and Scotland. Well, they did. Some of them are destroying books at the moment. I regard this as tragic.

But we can always write more books.
 
2014-05-20 01:42:23 PM  
Aphorisms are great but they only tell you what you want to hear. For new ideas, you need prose.
 
2014-05-20 01:47:44 PM  

brantgoose: You'd be surprised how many of your genes you share with your dog. Or with mice (about 50%). Or even with bananas (25%). I suspect that American and Canadian poltiicians are mostly bananas.

Since the advent of genetics and gene replication on a large scale, scientists have been using mutations in genes shared by humans or shared with other species to not only track the movements of people in prehistory, but also to figure how how closely species are related to each other.

The gene clocks (such as the Y-chromosme and mitochondrial DNA) may run at different speeds, but the mutations do occur with regularity, which enables scientists to build a family tree for humans and for life in general.

I've been reading books genetics and genealogy lately, especially the British population, since they are covered in the most detail.

It is complicated and fascinating, but much has been and can be learned.

There is a lot of misunderstanding among the general public, however, of what all this means. This is particularly true of nationalists and racists. They think the genes can be used to support their favourite prejudices. Not so.

Take my Y-chromosome, please!

Oops! That is ruder than I intended.

But seriously, the Y chromosome is used to track the movement of men (through war, trade, slavery, etc.). All men have one, and only men have them. They have 17 genes, one of which turns a girl fetus into a boy fetus at six weeks after conception. That is all it does. The other 16 genes are largely involved with sperm production and quality. That is all they do.

But you can use the junk DNA (non-coding for proteins and apparently largely used only for spacers in the gene code) to track the ancestry of men.

All men have a lineage consisting solely of men--their father, paternal grand-father and so forth. All women have a lineage consisting solely of their Mother, their Mother's Mother and so forth. These two lineages are the only ones consisting entirely of one sex or the other. A ...


thenewtraditionalists.com
 
2014-05-20 01:49:17 PM  
Human albino gene found in dogs. Well, he always did like to spend time in his lab

Anyone mention the gerbil found in Will Gere's jeans?

img.fark.net
 
2014-05-20 01:54:30 PM  
www.yee.ch
 
2014-05-20 02:09:42 PM  
Hey assholes, get them out of the farking sun.
 
2014-05-20 02:10:29 PM  
You know nothing, Jon Snow.
 
2014-05-20 06:25:44 PM  
Four paws up Subby!
 
2014-05-20 06:40:23 PM  
This gives me an idea for a game show. Put up a picture of a DNA sequence, and make the contestants guess whether the genome comes from:

COCK OR SPANIEL!

*wild applause*
 
2014-05-20 07:01:32 PM  
│ Human albino gene found in dogs.

Upon reading that, I thought they'd found that the human albino gene had somehow migrated to canines. Which, of course, is nonsense. It's simply that some humans and dogs have the same genetic mutation of the gene that causes albinism.
 
Displayed 31 of 31 comments

View Voting Results: Smartest and Funniest


This thread is closed to new comments.

Continue Farking
Submit a Link »
Advertisement
On Twitter





In Other Media


  1. Links are submitted by members of the Fark community.

  2. When community members submit a link, they also write a custom headline for the story.

  3. Other Farkers comment on the links. This is the number of comments. Click here to read them.

  4. Click here to submit a link.

Report