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(Salon)   You can't say there's no cure for cancer, but it will make you sicker than the disease, and cost you a small house   (salon.com) divider line 13
    More: Interesting, monoclonal antibodies, gene therapy, immunotherapy, Scientific American, switches  
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2361 clicks; posted to Geek » on 06 May 2014 at 3:17 PM (15 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2014-05-06 01:59:00 PM
static.musictoday.com

R.I.P. Bill Hicks

 
2014-05-06 02:35:07 PM
FTFA:  And yes, treatment is expensive-more than $100,000 a pop.

So...about the same as major heart surgery, I'm guessing.
 
2014-05-06 03:17:44 PM
One hundred grand?  So basically the same as two aspirin and an enema?
 
2014-05-06 03:27:46 PM
I hope this is better than the current cocktail of treatments. I saw my mother go through that for 5 years and it's a really ugly process
 
2014-05-06 03:49:53 PM

Ennuipoet: One hundred grand?  So basically the same as two aspirin and an enema?


Hey, Obama-care has successfully allowed the free market to control prices, you can now get three aspirin.
 
2014-05-06 03:51:52 PM

xanadian: FTFA:  And yes, treatment is expensive-more than $100,000 a pop.

So...about the same as major heart surgery, I'm guessing.


Actually, cheaper. Iirc the average cost of open heart in thr US is something like 175k. If it actually had a solid cure rate, there isn't a government or insurance company in the developed world that would balk at 100k for this.

Otoh, lots of stuff looks great in the lab. Unless there's solid phase 2 or 3 trial data on this, it's too early to get excited. 10 years away at best and probably another disapointment.
 
2014-05-06 04:02:28 PM

ikanreed: Ennuipoet: One hundred grand?  So basically the same as two aspirin and an enema?

Hey, Obama-care has successfully allowed the free market to control prices, you can now get three aspirin.


Who's gonna pay for the internal bleeding now?
 
2014-05-06 04:09:25 PM

neon_god: xanadian: FTFA:  And yes, treatment is expensive-more than $100,000 a pop.

So...about the same as major heart surgery, I'm guessing.

Actually, cheaper. Iirc the average cost of open heart in thr US is something like 175k. If it actually had a solid cure rate, there isn't a government or insurance company in the developed world that would balk at 100k for this.


I wouldn't be too sure about that. Remember that as a person grows older the chance of getting cancer approaches 1. There are going to be a lot of people needing this treatment, major heart surgery not so much.
 
2014-05-06 04:10:53 PM
Immunotherapy is a fantastic thing, and there are some really cool ideas making their way through trials these days.

That said, the current "hot idea" is monoclonal antibodies. The major pharmaceutical companies are all trying to make monoclonal antibodies for any cell surface marker or cytokine that's ever been associated with a difficult disease. You can certainly get a lot of funding if you've got a good antibody and a good target.

They're not the end all, be all of immunotherapy, though. The side effects range from "unpleasant" to "possibly worse than the disease in the long run." They're expensive as hell to make, which makes them costly for the consumer  and severely limits the production of generics/biosimilars.

We'll see what the future brings for better immunotherapies.
 
2014-05-06 04:28:07 PM

DerAppie: neon_god: xanadian: FTFA:  And yes, treatment is expensive-more than $100,000 a pop.

So...about the same as major heart surgery, I'm guessing.

Actually, cheaper. Iirc the average cost of open heart in thr US is something like 175k. If it actually had a solid cure rate, there isn't a government or insurance company in the developed world that would balk at 100k for this.

I wouldn't be too sure about that. Remember that as a person grows older the chance of getting cancer approaches 1. There are going to be a lot of people needing this treatment, major heart surgery not so much.


Yeah, true. The thing is that a person dieing of cancer is massively expensive, with all the complications, drawn out ICU stays etc. Not to mention that tens or hundreds of thousands per patient are often spent on current drugs that prolong life but offer little hope of a cure in any advanced case. Cost effectiveness for medical stuff is usually determined as cost per quality adjusted life year, or QALY, gained (how much longer you live, divided by what percent of a normal quality of life you expect in that time). It's hard to get an exact threshold out of anyone, but it's almost universally assumed to be above 50k per QALY for government health plans. Given that current treatments are already very expensive, and that curing a cancer patient is statistically going to generate a large number of QALYs, this treatment would definitely pass muster.
 
2014-05-06 06:52:52 PM

Ennuipoet: One hundred grand?  So basically the same as two aspirin and an enema?


You should do some comparison shopping on escorts. Yours is ripping you off.
 
2014-05-06 08:30:36 PM

xanadian: FTFA:  And yes, treatment is expensive-more than $100,000 a pop.

So...about the same as major heart surgery, I'm guessing.


And now that Obamacare is in place, it's not "cost you $100k" so much as its "cost the insurance company $100k".  That is, unless you're the kind of idiot who got a plan with a yearly cap on benefits.
 
2014-05-06 09:42:43 PM

Ennuipoet: One hundred grand?  So basically the same as two aspirin and an enema?


Pretty cheap.

upload.wikimedia.org
 
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