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(Google)   59 out of 80 dead as Ebola makes another run at the gates. Sleep tight   (google.com) divider line 103
    More: Scary, ebola, protective equipment, Guinean, Doctors Without Borders, World Health Organisation  
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13237 clicks; posted to Main » on 22 Mar 2014 at 7:00 PM (27 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2014-03-22 07:03:35 PM
"The Hot Zone" is a very good book worth reading on this subject, even if sometimes the author tries to guess/write fiction at what a person was thinking and what his motivations were even though the book is supposed to be non-fiction.
 
2014-03-22 07:04:30 PM
img.fark.net

For real this time.

/Damn
 
2014-03-22 07:04:31 PM
Newsflash from Madagascar:

img2u.info
 
2014-03-22 07:05:06 PM

Canton: [img.fark.net image 616x662]

For real this time.

/Damn


Shakes tiny fist....
 
2014-03-22 07:05:33 PM

skinink: "The Hot Zone" is a very good book worth reading on this subject, even if sometimes the author tries to guess/write fiction at what a person was thinking and what his motivations were even though the book is supposed to be non-fiction.


Terrifying book.
 
2014-03-22 07:06:19 PM

LesserEvil: Canton: [img.fark.net image 616x662]

For real this time.

/Damn

Shakes tiny fist....


Shakes one back

/Great minds
//It was gonna happen
///Etc, etc.
 
2014-03-22 07:06:36 PM
Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.
 
2014-03-22 07:08:02 PM
The problem:

download.lardlad.com

'Mmm, I couldn't wait to eat that monkey!'
 
2014-03-22 07:08:22 PM
i'm old. i think i'll spin 'the survivors' in the disk drive. no not that one. no. no. 1975-1977. i give credit for my public tv in the usa for airing this back in the day.
 
2014-03-22 07:10:14 PM
Nothing like a nice visit from your friendly hemorrhagic fever that turns your organs to soup and then jumps to the next host. Odd...if you think about it. A virus, that by it's nature, destroys the host that allows it to reproduce and live. Not too smart, but definitely deadly.
 
2014-03-22 07:10:35 PM
Thanks, Obama... I mean, Ebola.
 
2014-03-22 07:12:51 PM
Is happy with this development, pleased to meet you, and hopes you guessed his name.

upload.wikimedia.org
 
2014-03-22 07:14:47 PM

Bit'O'Gristle: Nothing like a nice visit from your friendly hemorrhagic fever that turns your organs to soup and then jumps to the next host. Odd...if you think about it. A virus, that by it's nature, destroys the host that allows it to reproduce and live. Not too smart, but definitely deadly.


You have summarized my dating life.
 
2014-03-22 07:16:20 PM

Bit'O'Gristle: Nothing like a nice visit from your friendly hemorrhagic fever that turns your organs to soup and then jumps to the next host. Odd...if you think about it. A virus, that by it's nature, destroys the host that allows it to reproduce and live. Not too smart, but definitely deadly.


Pretty much. It's not the most successful virus in terms of spread. (I'd actually give that to any cold virus floating around out there. Sure, the host's immune system typically kills it, but not before the thing has spread just everywhere the host has been.)

Um, it's possible I've read The Andromeda Strain a few too many times.

/One of Crichton's better works.
 
2014-03-22 07:16:39 PM

wildcardjack: Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.


From what I remember reading, the disease is fatal but the drawbacks it has is that it kills really really fast compared to other diseases and that it is lethal most of the time. Means there are less carriers walking around letting the disease incubate and spread because the people are just dying.
 
2014-03-22 07:16:44 PM
Do not expose yourself to the bodily fluids of an Ebola victim.

You probably shouldn't drink out of the same glass either.

And double dipping is out of the question.
 
2014-03-22 07:18:51 PM

megarian: Bit'O'Gristle: Nothing like a nice visit from your friendly hemorrhagic fever that turns your organs to soup and then jumps to the next host. Odd...if you think about it. A virus, that by it's nature, destroys the host that allows it to reproduce and live. Not too smart, but definitely deadly.

You have summarized my dating life.


That summarized my first marriage.  Which still hasn't ended, completely.

/thinks about french kissing an Ebola victim
 
2014-03-22 07:20:26 PM

megarian: Bit'O'Gristle: Nothing like a nice visit from your friendly hemorrhagic fever that turns your organs to soup and then jumps to the next host. Odd...if you think about it. A virus, that by it's nature, destroys the host that allows it to reproduce and live. Not too smart, but definitely deadly.

You have summarized my dating life.


img.fark.net
?
 
2014-03-22 07:23:26 PM

skinink: wildcardjack: Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.

From what I remember reading, the disease is fatal but the drawbacks it has is that it kills really really fast compared to other diseases and that it is lethal most of the time. Means there are less carriers walking around letting the disease incubate and spread because the people are just dying.


Hopefully that continues to remain true, if there's ever a mutation that increases the length of time before symptoms appear, we're in real trouble.
 
2014-03-22 07:26:29 PM
Limited to small outbreaks until a strain develops that can spread by aerosol.
 
2014-03-22 07:27:31 PM

Reverend J: skinink: wildcardjack: Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.

From what I remember reading, the disease is fatal but the drawbacks it has is that it kills really really fast compared to other diseases and that it is lethal most of the time. Means there are less carriers walking around letting the disease incubate and spread because the people are just dying.

Hopefully that continues to remain true, if there's ever a mutation that increases the length of time before symptoms appear, we're in real trouble.


Doesn't have to be a mutation. A microbiology student could just about make a version with a long latency period and airborne spread in a home lab, and we're just getting closer to that capability daily. Of course, they'd probably be the first person to melt.
 
2014-03-22 07:27:45 PM
Goddamnit.
 
2014-03-22 07:28:17 PM

skinink: "The Hot Zone" is a very good book worth reading on this subject, even if sometimes the author tries to guess/write fiction at what a person was thinking and what his motivations were even though the book is supposed to be non-fiction.


CSB

At the time of the Ebola Reston incident, I was a budding young chemist at Hazleton Laboratories in Vienna, VA. Before they got the CDC and eventually USAMRIID involved, they performed the necropsies on the dead monkeys down the hall from my lab (the monkeys were transported from the Reston primate facility to the necropsy lab in Vienna). You could have told us that the monkeys had ebola and none of us would have know what you were talking about. We were told to report any "flu-like" symptoms to the mammalian toxicology folks. If memory serves, I think we had two people get sick, but no one died. It was 100% lethal to the monkeys though.

We all freaked out when "The Hot Zone" came out. Since then, I've gone into computers - much less crazy biohazard exposure.

/CSB
 
2014-03-22 07:29:48 PM

Marcus Aurelius: megarian: Bit'O'Gristle: Nothing like a nice visit from your friendly hemorrhagic fever that turns your organs to soup and then jumps to the next host. Odd...if you think about it. A virus, that by it's nature, destroys the host that allows it to reproduce and live. Not too smart, but definitely deadly.

You have summarized my dating life.

That summarized my first marriage.  Which still hasn't ended, completely.

/thinks about french kissing an Ebola victim


/well, it doesn't sound like you would be much worse off.  Oh yes, you could be married to my ex wife. I wouldnt wish that on anyone.  You're better off with the ebola lip lock.
 
2014-03-22 07:32:18 PM

Bit'O'Gristle: Oh yes, you could be married to my ex wife. I wouldnt wish that on anyone. You're better off with the ebola lip lock.


One's a disease that utterly destroys you from the inside out until you wish for death, and the other is an African virus?
 
2014-03-22 07:41:24 PM

beer4breakfast: Limited to small outbreaks until a strain develops that can spread by aerosol.


Hate to tell you this, but it can spread via airborne droplet. Its no flu wafting around but if someone's hacking up blood keep your distance and keep their blood off of you
 
2014-03-22 07:41:43 PM

Marcus Aurelius: Do not expose yourself to the bodily fluids of an Ebola victim.

You probably shouldn't drink out of the same glass either.

And double dipping is out of the question.


I guess sex is out of the question too.
 
2014-03-22 07:42:34 PM

skinink: "The Hot Zone" is a very good book worth reading on this subject, even if sometimes the author tries to guess/write fiction at what a person was thinking and what his motivations were even though the book is supposed to be non-fiction.


Another vote for a "scarey as fark" book. Tom Clancy wrote a book (can't remember the title) that involved a terrorist ebola attack and I often wondered if he used Hot Zone as a source.
 
2014-03-22 07:42:58 PM
skinink
"The Hot Zone" is a very good book worth reading on this subject,


I was more thinking "Tom Clancy":
This Ebola outbreak is surely connected to the passengers with stolen passports on the missing Malaysian plane and both are linked to Russia stirring up shiat in Ukraine after an ex-NSA spy has defected to Moscow and the release of chemical weapon's in the Middle East by Russia's partner Syria. And it's certainly not a coincidence that Crimea started directly after Russia had the Olympics at another blacksea port.
I'm sure Jack Ryan is already hard at work figuring out what's behind all this.
 
2014-03-22 07:44:03 PM
It's too bad for the victims, but thank God this stuff kills too fast to sustain any large-scale outbreaks.

Epidemiologist's Lament: If only we could find the host...
 
2014-03-22 07:45:20 PM

Ginnungagap42: skinink: "The Hot Zone" is a very good book worth reading on this subject, even if sometimes the author tries to guess/write fiction at what a person was thinking and what his motivations were even though the book is supposed to be non-fiction.

CSB

At the time of the Ebola Reston incident, I was a budding young chemist at Hazleton Laboratories in Vienna, VA. Before they got the CDC and eventually USAMRIID involved, they performed the necropsies on the dead monkeys down the hall from my lab (the monkeys were transported from the Reston primate facility to the necropsy lab in Vienna). You could have told us that the monkeys had ebola and none of us would have know what you were talking about. We were told to report any "flu-like" symptoms to the mammalian toxicology folks. If memory serves, I think we had two people get sick, but no one died. It was 100% lethal to the monkeys though.

We all freaked out when "The Hot Zone" came out. Since then, I've gone into computers - much less crazy biohazard exposure.

/CSB


Would be interesting to see how many of you have antibodies against it. As far as ebola reston is concerned I'm not aware of it ever causing known human illness (for sure no fatalities). Of course the rule of thumb for that bug is "yeah, it hasn't done anything yet, but its fraternal twins are bastards and no one wants to be patient zero." Its treated with the same precautions as the other strains
 
2014-03-22 07:45:56 PM

NutWrench: skinink: "The Hot Zone" is a very good book worth reading on this subject, even if sometimes the author tries to guess/write fiction at what a person was thinking and what his motivations were even though the book is supposed to be non-fiction.

Another vote for a "scarey as fark" book. Tom Clancy wrote a book (can't remember the title) that involved a terrorist ebola attack and I often wondered if he used Hot Zone as a source.


It was Executive Orders, with a related scenario in Rainbow Six.
 
2014-03-22 07:48:24 PM

All Latest: Marcus Aurelius: Do not expose yourself to the bodily fluids of an Ebola victim.

You probably shouldn't drink out of the same glass either.

And double dipping is out of the question.

I guess sex is out of the question too.


Hemmorhagic fever viruses are nasty buggers when it comes to sex. You can detect live virus up to six weeks after infection for a bunch of them. Provided you survive the initial infection its best to keep it in your pants for quite a while
 
2014-03-22 07:49:28 PM

Boojum2k: Reverend J: skinink: wildcardjack: Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.

From what I remember reading, the disease is fatal but the drawbacks it has is that it kills really really fast compared to other diseases and that it is lethal most of the time. Means there are less carriers walking around letting the disease incubate and spread because the people are just dying.

Hopefully that continues to remain true, if there's ever a mutation that increases the length of time before symptoms appear, we're in real trouble.

Doesn't have to be a mutation. A microbiology student could just about make a version with a long latency period and airborne spread in a home lab, and we're just getting closer to that capability daily. Of course, they'd probably be the first person to melt.


As someone who just finished my dissertation working with hemorrhagic diseases, specifically looking at attenuating one of them, I can assure you this still isn't anywhere near easy. While the DIY movement is really cool I doubt many would be anywhere near the skill level to even look at modification and characterization of a pathogen, let alone a BSL4 pathogen.

On the other note, yes Ebola virus is very quick and actually fairly difficult to spread, at least the strains which are pathogenic to humans. Reston had evidence of airborne spread in NHPs but no clinical disease in exposed humans. The biggest factors are believed to be exposure to infected vector, shared needles (hospitals recycle them), and direct contact with fluids of near-deceased or deceased. They normally have very close family care in the clinics (aka families feed/bath/clothe) and very direct contact during some funeral rights.

This is the type of outbreak I would love to be involved with, if only EIS took more field based PhDs. Dang MDs and their lack of laboratory training.

Hope they get it under control soon.
 
2014-03-22 07:54:21 PM

Wicked Chinchilla: beer4breakfast: Limited to small outbreaks until a strain develops that can spread by aerosol.

Hate to tell you this, but it can spread via airborne droplet. Its no flu wafting around but if someone's hacking up blood keep your distance and keep their blood off of you


I was thinking something similar to the Reston strain described in The Hot Zone that only infected chimps.
 
2014-03-22 07:56:04 PM

PathologyFreak: Boojum2k: Reverend J: skinink: wildcardjack: Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.

From what I remember reading, the disease is fatal but the drawbacks it has is that it kills really really fast compared to other diseases and that it is lethal most of the time. Means there are less carriers walking around letting the disease incubate and spread because the people are just dying.

Hopefully that continues to remain true, if there's ever a mutation that increases the length of time before symptoms appear, we're in real trouble.

Doesn't have to be a mutation. A microbiology student could just about make a version with a long latency period and airborne spread in a home lab, and we're just getting closer to that capability daily. Of course, they'd probably be the first person to melt.

As someone who just finished my dissertation working with hemorrhagic diseases, specifically looking at attenuating one of them, I can assure you this still isn't anywhere near easy. While the DIY movement is really cool I doubt many would be anywhere near the skill level to even look at modification and characterization of a pathogen, let alone a BSL4 pathogen.

On the other note, yes Ebola virus is very quick and actually fairly difficult to spread, at least the strains which are pathogenic to humans. Reston had evidence of airborne spread in NHPs but no clinical disease in exposed humans. The biggest factors are believed to be exposure to infected vector, shared needles (hospitals recycle them), and direct contact with fluids of near-deceased or deceased. They normally have very close family care in the clinics (aka families feed/bath/clothe) and very direct contact during some funeral rights.

This is the type of outbreak I would love to be involved with, if only EIS took more field based PhDs. Dang MDs and their lack of laboratory training.

Hope they get it under control soon.


Its the funeral rights that tend to be particularly devastating. Its really depressing actually because these people have to say goodbye totheir loved ones and the EIS officers have to tell them they have to discard all their cultural norms or risk high chance of death. Once the outbreak is recognized the healthcare related transmissions can be clamped down but people tend to hold on to religious belief more tightly than money...
 
2014-03-22 07:56:57 PM

LesserEvil: Canton: [img.fark.net image 616x662]

For real this time.

/Damn

Shakes tiny fist....


One.  Farking.  Second.
 
2014-03-22 07:59:01 PM

beer4breakfast: Wicked Chinchilla: beer4breakfast: Limited to small outbreaks until a strain develops that can spread by aerosol.

Hate to tell you this, but it can spread via airborne droplet. Its no flu wafting around but if someone's hacking up blood keep your distance and keep their blood off of you

I was thinking something similar to the Reston strain described in The Hot Zone that only infected chimps.


Ah. Interestingly that outbreak in reston appeared to potentially have had true airborne tranmission given the geographical locations of the chimps in the facility and which ones got infected
 
2014-03-22 08:00:06 PM
If they just cook their hamburgers longer this wouldn't happen.
 
2014-03-22 08:00:30 PM

The Voice of Doom: I was more thinking "Tom Clancy":


Shush. He was right once, please don't tempt fate.

PathologyFreak: As someone who just finished my dissertation working with hemorrhagic diseases, specifically looking at attenuating one of them, I can assure you this still isn't anywhere near easy.


Oh, I know that. As you noted, very very few have the capability. I'm just noting it takes one motivated genius, or a team of lesser lights, for something ugly to happen. Not necessarily on the order of Clancy's Rainbow Six or Frank Herbert's The White Plague, but maybe a 9/11 scale incident.
 
2014-03-22 08:01:56 PM

Wicked Chinchilla: Ginnungagap42: skinink: "The Hot Zone" is a very good book worth reading on this subject, even if sometimes the author tries to guess/write fiction at what a person was thinking and what his motivations were even though the book is supposed to be non-fiction.

CSB

At the time of the Ebola Reston incident, I was a budding young chemist at Hazleton Laboratories in Vienna, VA. Before they got the CDC and eventually USAMRIID involved, they performed the necropsies on the dead monkeys down the hall from my lab (the monkeys were transported from the Reston primate facility to the necropsy lab in Vienna). You could have told us that the monkeys had ebola and none of us would have know what you were talking about. We were told to report any "flu-like" symptoms to the mammalian toxicology folks. If memory serves, I think we had two people get sick, but no one died. It was 100% lethal to the monkeys though.

We all freaked out when "The Hot Zone" came out. Since then, I've gone into computers - much less crazy biohazard exposure.

/CSB

Would be interesting to see how many of you have antibodies against it. As far as ebola reston is concerned I'm not aware of it ever causing known human illness (for sure no fatalities). Of course the rule of thumb for that bug is "yeah, it hasn't done anything yet, but its fraternal twins are bastards and no one wants to be patient zero." Its treated with the same precautions as the other strains



Two of the mammalian tox techs got sick with very bad flu-like symptoms. Of course, it could have been two very bad cases of flu for all I know. And yeah, zero human fatalities.

I worked in a radiolabeling lab. We always joked that the higher than normal background radiation killed all the bugs in our lab.
 
2014-03-22 08:02:16 PM

Bit'O'Gristle: Nothing like a nice visit from your friendly hemorrhagic fever that turns your organs to soup and then jumps to the next host. Odd...if you think about it. A virus, that by it's nature, destroys the host that allows it to reproduce and live. Not too smart, but definitely deadly.


That's the sign of a young virus.  Old viruses mutate to let the host live.

That's actually a bad way to look at it because it implies that the virus has a directive.  It doesn't.  It just multiplies, as the Good Agent Smith once said.  What happens is that a virus that is too strong kills its hosts, a virus that is just right will let its hosts live.  The too-strong virus will kill faster than it can spread while the mutation that allows the hosts to live will be able to spread farther.

See?  Isn't it beautiful?  No conscious intent is required.  The nature of virus transmission will always self-correct to the model where the virus isn't TOO deadly.  As long as the organisms that are getting the virus are smart enough to shun their ill instead of helping them... oh dear.

/we are screwed by our very compassion
 
2014-03-22 08:14:17 PM

wildcardjack: Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.


It's passed on by contact with bodily fluids. Given the symptoms, not going to have a lot of people making contact with an infected person.

skinink: the disease is fatal


The mortality outbreak varies pretty widely based on the outbreak. The worst have been around 95% and the best have been, if I remember right, around 60%. The variation could mean a few things, or it could mean nothing other than just random luck.

BTW anyone up for a Marburg or dengue outbreak? How about Lassa?
 
2014-03-22 08:16:20 PM

WhyteRaven74: wildcardjack: Always gets me that the numbers are so low. It must present symptoms at almost the same time as it becomes contagious.

It's passed on by contact with bodily fluids. Given the symptoms, not going to have a lot of people making contact with an infected person.

skinink: the disease is fatal

The mortality outbreak varies pretty widely based on the outbreak. The worst have been around 95% and the best have been, if I remember right, around 60%. The variation could mean a few things, or it could mean nothing other than just random luck.

BTW anyone up for a Marburg or dengue outbreak? How about Lassa?


How about no? Does no work for you?

/Aaaaahhhh!  Run away!!!
 
2014-03-22 08:16:32 PM
Africa. The world's petri dish.
 
2014-03-22 08:17:37 PM
BTW the worrisome thing with this outbreak, Guinea is nowhere near what was Zaire, now Democratic Republic of the Congo, where ebola is normally found.
 
2014-03-22 08:23:45 PM
Since Ebola is a virus, if one survives, are they then resistant to that strain?
 
2014-03-22 08:25:13 PM
What was tthat movie that addressed an epidemic?  not based in Africa, but the result of a chimese pig farming operation. Not "12Monkeys", but close to it.
 
2014-03-22 08:35:54 PM

WhyteRaven74: BTW the worrisome thing with this outbreak, Guinea is nowhere near what was Zaire, now Democratic Republic of the Congo, where ebola is normally found.


Those places are all in Russia somewhere.  I'll start to worry when it shows up in Canada.
 
2014-03-22 08:44:23 PM

Ex-Texan: What was tthat movie that addressed an epidemic?  not based in Africa, but the result of a chimese pig farming operation. Not "12Monkeys", but close to it.


you sound drunker than i am

/must rectify
 
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