If you can read this, either the style sheet didn't load or you have an older browser that doesn't support style sheets. Try clearing your browser cache and refreshing the page.

(EurekAlert.org)   Mosquito-borne virus only attacks cancerous tumors. Still no cure for... malaria   (eurekalert.org) divider line 48
    More: Ironic  
•       •       •

9923 clicks; posted to Main » on 01 Feb 2004 at 2:42 PM (10 years ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



48 Comments   (+0 »)
   

Archived thread
 
2004-02-01 10:42:16 AM
mmm, Tumors.

Here's hoping the next virual genetic engineer doesn't splice the wrong gene.
 
2004-02-01 02:48:48 PM
I am so sick of reading these "medical breakthroughs" that state we're still years from human trials...

Call me when they cure something. T don't think the medical community has developed an actual cure in about a zillion years. Too much money goes into medical reseach. There is no incentive for a cure, only treatment. Why cure something and kill a cash cow. We should immediately stop funding all medical research and just bank the money. Offer rewards for cures and we will get cures not treatment.
 
2004-02-01 02:49:05 PM
Kudos to the headline writer.

This is very interesting -- I wonder where the mutation occured within the virus' chromosomes and how it enabled it to specifically target cancer cells.

Very interesting alternative to chemo.
 
2004-02-01 02:49:05 PM
IT IS NOT A TUMOR.

/sorry
 
2004-02-01 02:53:38 PM
Rhadamanthus: reading the article might give you some insight as to why it targets only cancerous cells
 
2004-02-01 02:57:21 PM
Isn't there already a cure-ish cure-type cure-thing for malaria? I mean at least a treatment to prevent death from dying from the death-related death-causing deadly events caused by malaria's death-related properties.
 
cot
2004-02-01 02:57:51 PM
"T don't think the medical community has developed an actual cure in about a zillion years"

I pity the fool who badmouths recent medical advances.
 
2004-02-01 02:59:00 PM
Virii are going to be a common day cure. My biology teacher was speculating on this years and years ago, I just thought he was ranting and didn't think too much about it at the time.
 
2004-02-01 03:02:24 PM
Maximilius
T don't think the medical community has developed an actual cure in about a zillion years. Too much money goes into medical reseach.

*restrains impulse to repeat the Mr. T Joke*

Where do you think cures come from? Medical research produces cures.

Yes, the greedy pharmaceutical companies are only interested in treating symptoms, but they aren't the only ones doing research. Universities and government labs are also engaged in research, and they aren't profit driven. Funnel money to them, and then let the pharmaceutical companies market the result...and don't let the greedy buggers jack up the price, since they haven't been footing the bill for R&D and don't have multi-million dollar investments to recoup.
 
2004-02-01 03:02:53 PM
now if we can only cure those pesky "headaches" the wife
always gets.
 
2004-02-01 03:03:18 PM
Do you let you mechanic "treat" you car troubles?

"We can't fix that valve noise but if you buy this gas additive for $75 a pint and pour that after every fill up, your car will be less noisy."

Fark that!
 
2004-02-01 03:05:27 PM
2004-02-01 03:02:53 PM Impudent Domain


now if we can only cure those pesky "headaches" the wife
always gets.


Roofies always seem to work.
 
2004-02-01 03:06:34 PM
You assume that if we were to stop funding medical research, research would stop.

If instead you offered a reward for a cure, companies would still continue to do the research, except they would start looking for a cure and stop looking for ways to prolong your life while suffering from the disease.
 
2004-02-01 03:06:38 PM
This actually sounds pretty awesome. If I had cancer I'd willingly let myself be injected with this virus.

Don't they already have human subjects? What is the rate of cancer in the humans who contracted the virus from mosquitoes?
 
2004-02-01 03:08:19 PM
What about quinine?

/got nothin
 
2004-02-01 03:15:14 PM
Maxamillius
If instead you offered a reward for a cure, companies would still continue to do the research, except they would start looking for a cure and stop looking for ways to prolong your life while suffering from the disease.

How big a reward? Research is *expensive*. You can pour a lot of money into dead-end avenues of investigation before coming up with anything. While all this is going on, the company still needs to earn some income to fund the R&D, which means they continue selling things that prolong your suffering. Even if the reward is big enough to justify looking for a cure instead of a palliative, we still have a situation where the companies can charge sky-high prices.

Institutional research is the way to go.
 
2004-02-01 03:18:28 PM
Ok we continue doing the same thing and again I ask, when was the last real cure?
 
2004-02-01 03:24:33 PM
There are about 8 different commericially available cures and preventatives for malaria...

/goin' to Africa in a few months, I better know that
 
2004-02-01 03:27:20 PM
Actually there is a cure for Malaria: it's called DDT.

You can thank environmentalists for killing millions with their sweeping ban of DDT.

 
2004-02-01 03:38:46 PM
I've been taking Plaquenil since 1989 for my Lupus, but according to the insert, the main purpose of Plaquenil is as an anti-malarial.
 
2004-02-01 03:44:55 PM
According to the study, published in the January 2004 issue of the journal Nature Biotechnology, the Sindbis virus is effective at killing tumors in mice at every location tested--whether the growths occur under the skin, in the pancreas, in the main body cavity, or in the lungs.

The amount of time and the number of injections needed to cause tumor remission varied, depending on the type of cancer, but in general mice were given injections of the virus daily. Within a month to two months later, many tumors disappeared completely.


Huzzah! A cure for cancer! Behold as the first of many fark cliches dies.
 
2004-02-01 03:45:08 PM
Bondith

I disagree; I think university and government research is very much profit driven. First you do the research that will make money for the university (through patents and grants and alumni funding) then if you can afford it you do the research you REALLY care about.
 
2004-02-01 03:50:13 PM
It would seem to me that there would be thousands of people with cancer who would readily line up to be injected with this virus right now - who WON'T BE AROUND by the time they get tired of fooling around with mice.

A school gets a ton of money to *research* things like this; not figure it out, put it out there and close up shop. So they'll milk it for what it's worth....

This is essentially a *cure for cancer in mice*. Inject it anywhere, it goes anywhere, and in two months a tumor anywhere dissipates to nothing....

*They've cured cancer for mice!*


A) How do cancer cells differ from human cancer cells?
B) Does the virus proliferate in human blood?

If A is "much different" than humans, then it's useless to "research" it on mice, correct?

If B is "yes" - then is should be in humans, NOW.
If B is "we don't know" - then that should be the RESEARCH.

Sendbis, a viral cure for cancer in mice. That should be headline news; and people should be up in arms to push this to the front for human trials, or research to MAKE IT WORK IN HUMANS.
 
2004-02-01 03:56:29 PM
I have a friend who is currently working on an modified HSV-1 vector at the UofPA. It's been remarkably efficient at destroying tumors, and isn't too harmful.

So why aren't we giving human trials? Because it's dangerous. A French research team tested the hell out of a viral genetic cure for X-linked severe human immunodeficiancy syndrome. They gave it to 11 boys with the disease. 2 developed cancers, because the virus accidentially replaced genetic material a cell division control gene. Immediately the trial was shut down and the French government refused to allow human trials of viral treatments.

So fark you, Maxamillius , and everyone who thinks that it's taking so farking long to make miracle cures because everyone is greedy. Go on the inside before you say it's profit motive.
 
2004-02-01 03:58:11 PM
RubensHakkamacher

If you would stop your ranting...this was a mouse model for a human disease. They do this first. Then they do lab-grown human tissue. Then they'll do humans. That's the F*CKING NEXT STEP!
 
2004-02-01 04:01:28 PM
You both have good points, pkjun and RubensHakkamacher. I'd side more with pkjun and be on the safe side, though. Except if I had cancer, I personally wouldn't worry about the side effects of this treatment. What's it gonna do, give me cancer?
 
2004-02-01 04:02:48 PM
OUISCH Is the Plaquinil working? has your condition
deteriorated since 1989?
My mother died of Lupus, way back in 87. she had symptoms
for many years before.
 
2004-02-01 04:05:53 PM
I think most people in medicine and research are motivated
by profit AND they are motivated by trying to help people.
The two are not mutualy exclusive.
 
2004-02-01 04:07:40 PM
I think yellow fever would have been a better mosquito born virus to choose. Malaria is nothing these days. You get it, take chloroquine (or mefloquine), go crazy for a couple of days, and get better. If you take a prophylactic, you have little chance of getting it anyway. I have been in Africa during the malaria season and slept outside with no mosquito net. I looked like that guy on Shogun, but I never got malaria, and I was taking the weakest prophylactic there is...doxycycline (also cures anthrax and is used as acne medicine).
 
2004-02-01 04:08:45 PM
After all the damage the mosquito's done, I'd say it owes us.
 
2004-02-01 04:52:48 PM
AvoidingWork
I disagree; I think university and government research is very much profit driven.

I'd like to congratulate you on simply saying "I disagree" and not "Fark you, you farking moron. What the fark is farking wrong with you, farktard?"

First you do the research that will make money for the university (through patents and grants and alumni funding) then if you can afford it you do the research you REALLY care about.

I've only been in grad school for about a month, and I never really paid attention to such things when I was an undergrad (since my school didn't have a research mandate), but you could have something there. It's very difficult to get funding if your research doesn't have some form of useful application. That's about all I can say, since I'm still somewhat in the dark as to how the grant process works (sometimes I wonder how I managed to make it into grad school while being so clueless). All I know is that my supervisor got $500,000 recently.
 
2004-02-01 05:04:01 PM
This virus that is carried by mosquitos in a certain part of Egypt has no relation to malaria. Malaria is a protozoan parasite which is transmitted by mosquitos, not a virus.

This sounds like a weak version of West Nile virus, if anything.

Cool that they actually found out something useful and it looks really promising, though whether it can ever work in humans is unknown, but it seems to work well in GMO mice.

BTW: India and at least one country in Africa still manufacture DDT mainly for mosquito control.
 
2004-02-01 05:25:19 PM
there's actually no reason for medical companies to actually find cures for the disease...look at the ridiculous amount of money they make on "treatments" like chemotherapy, etc.

What's their motivation?

I'm not usually a conspiracy theorist...in fact I'm not...but I do believe that a cure for cancer has been found...but medical companies are going to try and suck as much cash out of us as possible before they release it.
 
2004-02-01 05:32:54 PM
maybe now france will start the next world war..
 
2004-02-01 06:04:07 PM
Impudent Domain

I read a study somewhere that said sex releases chemicals in the body that are good for headaches.
 
2004-02-01 06:04:53 PM
I worked for Cancer Research UK last year on a novel protein implicated in tumour progression.

Expensive, time consuming research? Yes.
A waste of time? No.

To all the morons that are criticising lab research - go and check it out for yourself. Lab research is the reason yourself and those around you are living so well at the moment.

For instance, I'd love to see you deal with a complicated urinary tract infection without the use of laboratory produced antibiotics, or an advanced stomach ulcer, or terminal cancer. You get the picture.

Learn about these things, or shut up.
 
2004-02-01 06:21:31 PM
You want irony? Try this:

now if we can only cure those pesky "headaches" the wife
always gets.


The chemicals released by the brain during orgasm have analgesic properties, in addition to their tendency to relieve stress. In other words, the best cure for a headache is a roll in the hay. Tell that to the wife next time she complains.
 
2004-02-01 06:35:33 PM
NavyBlues - Kindergarten Cop, right ? I gots to know.
 
2004-02-01 06:50:25 PM
macaw: I thank the farktard farmers for using DDT by the metric farking ton. It was used by the ounce to fight Malaria by spraying the inside walls of homes with 10% solution. I am glad it was banned, birds are more useful than people but thanks to agrobiz we cannot have our cake and eat it to.
 
2004-02-01 07:57:45 PM
bootman
thanks to agrobiz we cannot have our cake and eat it to.


Sure you can. It will simply give you cancer :)
 
2004-02-01 09:11:27 PM
I don't get it... All this time, and no cures for cancer. Then suddenly, there's like five of them. Mind you, it's a good thing...

The so-called "reovirus" being developed by Oncolytics Biotech (a naturally ocurring virus that they've been working on which does pretty much the same thing, and has already been tested on humans...and works) looks like the most promising one I've seen. I saw a before and after set of pictures from a woman who had a gross tumor on her neck, and it's just...gone. Vanished. Poof.

I guess Fark can't use the "no cure for cancer" headlines anymore, but somehow "no cure for herpes" doesn't have the same ring...
 
2004-02-01 10:06:40 PM
Still no cure for scrofula?
 
2004-02-01 11:09:56 PM
I have forwarded this article to my Oncologist here in Mexico. They say that one's hope is the last to die......
 
2004-02-01 11:56:52 PM
They found a cure for East Timor? Finally!

/on a roll tonight..

/not really
 
2004-02-02 01:36:22 AM
cbm5:

Don't they already have human subjects? What is the rate of cancer in the humans who contracted the virus from mosquitoes?

That's an excellent point. I don't know why everyone here chose to ignore it.

If I had cancer, I'd head to a place where the mosquitos that carry this disease hang out, cover myself with gravy, and let nature take its course.
 
2004-02-02 06:35:11 AM

Buggery!! There goes the reason for wiping out mosquitos. I hate the little bastards.

2004-02-01 06:21:31 PM SimuLord
You want irony? Try this:

now if we can only cure those pesky "headaches" the wife
always gets.

The chemicals released by the brain during orgasm have analgesic properties, in addition to their tendency to relieve stress. In other words, the best cure for a headache is a roll in the hay. Tell that to the wife next time she complains.

That's assuming you can give her an orgasm.

 
2004-02-02 11:34:09 AM
 
2004-02-02 03:17:25 PM
macaw It wasn't the environmentalists banning DDT that helped a resurgence of malaria in the third world.

In fear of starting another evolution flame-war, it was the development of resistance to DDT by mosquitoes that helped malaria come back. Most mosquitoes now can bathe in DDT with virtually no effects. I've seen pictures of the buggers with crystals of DDT literally precipitating out of their bodies, they are so full.

Note that DDT is still manufactured in the United States, and shipped to many of these third world nations, to be used in greater and greater, increasingly expensive, increasingly ineffective amounts every year. The environmental damage this does to birds is still underway, and may wipe out many species (if you recall, many of our birds fly south for the winter, eating bugs that have been bathed in DDT).

If you want someone to blame for DDT/Malaria, look to the giant chemical corporations and the governments they have in their pockets.

And this virus has no relation to malaria whatsoever. It is indeed a form of encephalitis (as is West Nile virus, and numerous other mosquito borne diseases such as St. Louis encephalitis, Western equine encephalitis, Japanese encephalitis and La Crosse encephalitis). However it tends to be milder than most of those.

Note that the effect these viruses have on different species can be very different. Western equine encephalitis is dangerous to horses, but barely effects humans. West Nile is very deadly to corvids (crows, ravens, magpies), nasty to other birds, and relatively mild (usually) to humans. No telling what a virus that effects cancer in mice will do to us.
 
Displayed 48 of 48 comments



This thread is archived, and closed to new comments.

Continue Farking
Submit a Link »






Report