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(io9)   Science finds that the secret to living to be really, really old lies with people who have been able to become really, really old   (io9.com) divider line 47
    More: Obvious, George Church, genetic variation  
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2855 clicks; posted to Main » on 03 Jan 2014 at 5:32 PM (33 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



47 Comments   (+0 »)
   
View Voting Results: Smartest and Funniest
 
2014-01-03 05:35:56 PM
wow...
 
2014-01-03 05:36:45 PM
Two words: immortal atoms.
 
2014-01-03 05:37:03 PM
Just in... studies have shown that people who have more birthdays tend to live longer.
 
2014-01-03 05:37:23 PM
The secret is to avoid dying, says ace reporter Ric Romero.
 
2014-01-03 05:39:20 PM
So if there is no obesity epidemic because of genetics how can their be an "epidemic" of people living past 110 that is due to genetics?
 
2014-01-03 05:39:23 PM

bingethinker: The secret is to avoid dying, says ace reporter Ric Romero.


Hob Gadling is not impressed.
 
2014-01-03 05:40:20 PM
The actuarial table for "old" hasn't changed much.  The mean lifetime of someone who reaches 100 is about the same now as it was 50-100 years ago.  Science has not extended longevity but has made great strides in infant mortality which tends to fool the public with "life expectancy."  Anyone old enough to read has passed the most daunting part.
 
2014-01-03 05:41:39 PM
Choose wisely.

static1.wikia.nocookie.net
 
2014-01-03 05:42:12 PM
I prefer to try to throw myself at death, and miss.
 
2014-01-03 05:43:55 PM
You have to lie with someone that is really, really old?  Well, ok I guess, here goes.
 
2014-01-03 05:43:57 PM
While I can appreciate these research studies, they tend to tick me off when they inevitably state the obvious with no beneficial scientific progression.

Go find a cure for cancer, HIV, and bacterial resistance, dammit.
 
2014-01-03 05:44:24 PM
The best soylent green is made from the longest aged ingredients
 
2014-01-03 05:44:51 PM
which could lead to a gene therapy that promotes longevity

The Baby Boomers are going to do this just to spite the rest of us.
 
2014-01-03 05:46:03 PM
If people are all gonna start living till 110, society's gonna be in serious trouble.
 
2014-01-03 05:48:02 PM
The Howard Families just went into lock down and are planning their escape as we speak.
 
2014-01-03 05:57:32 PM
My great grandma is still alive and over 100. Still in pretty good shape - up and about, lives in "assisted" living but isn't in a nursing home. I don't know if living that long is a blessing or a curse, but at least she's not miserable or anything.

Her kids are in terrible health so I don't hold out hope that I've got those genes though. I'll make sure to post on fark if I make it to 100 though. Ha.
 
2014-01-03 06:07:34 PM

tbeatty: The actuarial table for "old" hasn't changed much.  The mean lifetime of someone who reaches 100 is about the same now as it was 50-100 years ago.  Science has not extended longevity but has made great strides in infant mortality which tends to fool the public with "life expectancy."  Anyone old enough to read has passed the most daunting part.


Yep. Back in the 19th century (and still today in some third world countries), half the children didn't make it to their fifth birthday. That tends to skew the statistics.
 
2014-01-03 06:08:01 PM
Listening to those people theorize why they lived so long is always a treat.  It's always some backwoods theory on eating a carrot every day, or some weird thing they've done like a brisk walk every night at exactly 2am.
 
2014-01-03 06:09:39 PM
Next year they are starting human trials on a compound that in mice reverse the damage caused by the aging process, so things could get interesting soon. We all may wind up retiring at 150, assuming anyone but the super wealthy will ever be able to afford regular treatment.
 
2014-01-03 06:10:51 PM
Kill them! Steal their blood.
 
2014-01-03 06:11:38 PM

WinoRhino: Listening to those people theorize why they lived so long is always a treat.  It's always some backwoods theory on eating a carrot every day, or some weird thing they've done like a brisk walk every night at exactly 2am.


Lean that one weird trick to keep the grim reaper at bay!
 
2014-01-03 06:12:35 PM

Fluid: If people are all gonna start living till 110, society's gonna be in serious trouble.


We already are with our largest generation hanging on till 80.
 
2014-01-03 06:18:44 PM

WinoRhino: Listening to those people theorize why they lived so long is always a treat.  It's always some backwoods theory on eating a carrot every day, or some weird thing they've done like a brisk walk every night at exactly 2am.


The one lady ate 2 lbs of chocolate a day...2 lbs!  Now that sounds like a plan to me!
 
2014-01-03 06:20:42 PM

DigitalCoffee: The Howard Families just went into lock down and are planning their escape as we speak.


Came here to say this, leaving satisfied.

/well done, that man.
 
2014-01-03 06:24:20 PM
bingethinker:
Yep. Back in the 19th century (and still today in some third world countries), half the children didn't make it to their fifth birthday. That tends to skew the statistics.

My Mother has gotten really into the whole Ancestry.com/family tree thing the last few years. It's amazing how many children in our families history died really young. There are like 10 instances of couples having like 6 or 8 kids and only 2 or 3 survived.
 
2014-01-03 06:25:41 PM
Let's just take care of this now. . .img.fark.net
 
2014-01-03 06:30:57 PM

TinyFist: bingethinker:
Yep. Back in the 19th century (and still today in some third world countries), half the children didn't make it to their fifth birthday. That tends to skew the statistics.

My Mother has gotten really into the whole Ancestry.com/family tree thing the last few years. It's amazing how many children in our families history died really young. There are like 10 instances of couples having like 6 or 8 kids and only 2 or 3 survived.


They sound very careless.
 
2014-01-03 06:41:58 PM

Nicholas D. Wolfwood: DigitalCoffee: The Howard Families just went into lock down and are planning their escape as we speak.

Came here to say this, leaving satisfied.

/well done, that man.


Thanks. I wonder if they even teach stuff like this anymore to the youngins.
 
2014-01-03 06:53:39 PM

bingethinker: The secret is to avoid dying, says ace reporter Ric Romero.


...so far, so good.
 
2014-01-03 07:17:09 PM
My grandmother is over 100 now (I think she's 105 now). Apparently she's still quite spry.
 
2014-01-03 07:41:42 PM

tbeatty: The actuarial table for "old" hasn't changed much.  The mean lifetime of someone who reaches 100 is about the same now as it was 50-100 years ago.  Science has not extended longevity but has made great strides in infant mortality which tends to fool the public with "life expectancy."  Anyone old enough to read has passed the most daunting part.


So you're saying that the secret to immortality is to be illiterate? Damn, too late! :(

Personally I plan to never die. We'll see how that goes.
 
2014-01-03 07:44:29 PM

Snazzy1: WinoRhino: Listening to those people theorize why they lived so long is always a treat.  It's always some backwoods theory on eating a carrot every day, or some weird thing they've done like a brisk walk every night at exactly 2am.

The one lady ate 2 lbs of chocolate a day week...2 lbs!  Now that sounds like a plan to me!


FTFY
 
2014-01-03 07:48:21 PM

cgraves67: Kill them! Steal their blood.


Why kill them? I've got two locked in my basement right now. I give them each a bottle of bourbon a three cigars each day and take just enough blood to pay the rent.
 
2014-01-03 07:51:28 PM

DigitalCoffee: Nicholas D. Wolfwood: DigitalCoffee: The Howard Families just went into lock down and are planning their escape as we speak.

Came here to say this, leaving satisfied.

/well done, that man.

Thanks. I wonder if they even teach stuff like this anymore to the youngins.


Haven't had a chance to push a lot of RAH, but I *was* able to turn on pretty much all of the ankle-biters in a small north central PA town (pretty rural, fairly redneck) on to Hiyao Miyazaki, to the point where the local stores need to stock the stuff now.

(And my best bud - and his Mom (a real Hazel Stone, right down to the red hair) made sure their local libraries were stocked with Heinlein.)
 
2014-01-03 07:53:10 PM

ReverendJimBobHammer: cgraves67: Kill them! Steal their blood.

Why kill them? I've got two locked in my basement right now. I give them each a bottle of bourbon a three cigars each day and take just enough blood to pay the rent.


Also helps that you can c... hang on,

"SHUT THE F*CK UP IN THERE, YOU OLD HAGS!"

Sorry, anyways, it also helps that you can cash their Social Security checks.
 
2014-01-03 08:02:29 PM
Staying away from Samarra is a good idea.
 
2014-01-03 08:03:59 PM
I hope TechnoBevets shows up to learn us real good.
 
2014-01-03 08:06:13 PM

TinyFist: ReverendJimBobHammer: cgraves67: Kill them! Steal their blood.

Why kill them? I've got two locked in my basement right now. I give them each a bottle of bourbon a three cigars each day and take just enough blood to pay the rent.

Also helps that you can c... hang on,

"SHUT THE F*CK UP IN THERE, YOU OLD HAGS!"

Sorry, anyways, it also helps that you can cash their Social Security checks.


Should I feel bad that I laughed at that? Naw, I know I'm a bad person but I have high self esteem.
 
2014-01-03 08:09:00 PM

mrlewish: So if there is no obesity epidemic because of genetics how can their be an "epidemic" of people living past 110 that is due to genetics?


My personal theory:

Obesity is due to dieting.

No seriously, hear me out.  Calories In/Out is both totally correct and entirely misleading because your metabolism adapts to Calories In.   So I WAS at 320 and eating 6000 calories a day (college.  All-nighters can be done with food instead of coffee, and I was in a place with infinite cookies), dropped to 300 by eating 3000 calories a day and then stabilized, threw in exercise, and dropped to 270-275 by eating 800-1500 calories a day (and fasting on weekends) and then stabilized.  You CANNOT sit there and tell me that metabolism is independent of Calories In, because I've seen it.  It sucks ASS.  Cutting out 2 meals and adding 7 miles/day of bike riding lost me a mere 15% of body weight.

And since we evolved to not like increasing our metabolisms, what ends up happening when we diet is:

1) Stop eating, lose a bunch of weight
2) Plateau.  Either stop eating even more and repeat Step 1, or hit our target weight and then stop the diet.
3) Add back in all the calories that we had been eating before Step 1.
4) Gain EVEN MORE WEIGHT while our metabolisms slowly adjust back to the additional calories.
5) Diet again.

Oh, and every time you have something that you're not used to (Christmas), it just goes straight to the thighs.

So since everyone and their grandmother is dieting, everyone is farking up their metabolisms, becoming "diet-proof" (since their metabolisms are now designed for 1300 calories a day), and gaining fark-tons of weight when they quit their diets.

/And if you really think about it, the only way to lose weight is to ratchet.  Diet hard for 3 days (before the metabolism freaks out), recover metabolism for 11 days, repeat until target weight and diet.
//Seriously tired of eating 2/3rds what my coworkers do, and being 3/2ths their size.
///Any rec's on a dumbbell set, since I should probably start caring about muscles other my legs (biking) again.
 
2014-01-03 08:16:14 PM

meyerkev: /And if you really think about it, the only way to lose weight is to ratchet.


I was with you to this part. IMHO nobody should ever "diet" ever. I've never once dieted in my life. I eat what I eat and I exercise quite a lot. When I feel fat I maybe cut out the worst of the junk food and run a few more miles. Or maybe not.

If you want to lose weight you should slowly adopt better, sustainable habits and plan to stick with them until the day you die. IMHO.
 
2014-01-03 08:21:40 PM
it's more important to live a life filled with meaning
noiselesschatter.com
 
2014-01-03 08:31:57 PM

Jument: meyerkev: /And if you really think about it, the only way to lose weight is to ratchet.

I was with you to this part. IMHO nobody should ever "diet" ever. I've never once dieted in my life. I eat what I eat and I exercise quite a lot. When I feel fat I maybe cut out the worst of the junk food and run a few more miles. Or maybe not.

If you want to lose weight you should slowly adopt better, sustainable habits and plan to stick with them until the day you die. IMHO.


Basic Thesis:

* Metabolism follows diet/lifestyle.  If you're stable at 4000 calories and sitting on your ass, and jump down to 1500 and P90X, you'll stabilize at 1500 (albeit a LOT of pounds and extra muscle mass later).  Ditto for 1500 -> 4000.
* For very, very good evolutionary reasons, your metabolism tracks down a LOT faster than it tracks up.
* So if you diet, you'll drop tons of weight and then stabilize because your metabolism drops.  When you stop dieting, you'll gain all that weight back and then some more because your metabolism takes longer to jump back up.
* So therefore, the way to diet (for purposes of losing weight independent of health) is:
1) Adopt the reasonably healthy habits (diets, exercise) you want to have until the day you die.
2) Wait until you stabilize.
3) Then to drop weight:
* Diet hard for 3 days.  Drop 2-3 pounds (Not joking).
* Before your metabolism starts tracking the drop, stop dieting.
* Stabilize again
* Repeat

/And I'm willing to bet that I've done way more massive, repeated weight gain/loss than anyone here in the thread, and I've seen this pattern every single time.  240->280 (8 months) ->240 (4 months) -> 300 (8 months) - 320 (stable-ish for 3 years) ->295 (2 months)->300 (cracked ribs, 3 month recovery, ate less though)->270 (2 months).  Eating like I'd like to eat now (For example: Adding breakfast back in for the first time in 4 years), and preparing to gain 20 pounds before I stabilize, and then start ratcheting.
//Because 1.5 meals a day, no snacks, more exercise than I've ever done in my life, and no weight loss sucks.
 
2014-01-03 09:27:47 PM

Nicholas D. Wolfwood: DigitalCoffee: Nicholas D. Wolfwood: DigitalCoffee: The Howard Families just went into lock down and are planning their escape as we speak.

Came here to say this, leaving satisfied.

/well done, that man.

Thanks. I wonder if they even teach stuff like this anymore to the youngins.

Haven't had a chance to push a lot of RAH, but I *was* able to turn on pretty much all of the ankle-biters in a small north central PA town (pretty rural, fairly redneck) on to Hiyao Miyazaki, to the point where the local stores need to stock the stuff now.

(And my best bud - and his Mom (a real Hazel Stone, right down to the red hair) made sure their local libraries were stocked with Heinlein.)


Bravo for you! Now get them into Mamoru Hosoda (The Girl Who Leapt Through Time, Summer Wars, Wolf Children...)

/don't think that they're ready for Makoto Shinkai just yet
//keep fighting the good fight
 
2014-01-03 10:19:51 PM
DigitalCoffee: //keep fighting the good fight.

Ever and always.  In truth, I never do as much as I *should* do.  But I always enjoy it when I manage to pull off something that works.

I'm no good trying to help unscrew people's personal problems, and there's damn little my skills lend themselves to for making the world a better place, but ever since cheap IBM PC compatibles became a thing, I've had fun building PCs and passing them along to people who *needed* them to help make a difference in their lives.

Back in '85 or thereabouts, a decent machine could go a couple thousand, but they were a lot cheaper for someone who could build a machine from mail-order parts.  I've gotten writers and artists started on machines, and they've often gone on to some pretty good things.

For someone like me who is in awe of people with creativity, but has damn little himself, it's a way to contribute.
 
2014-01-04 01:04:40 AM
"Lies" is the key word here. They're not giving that secret up for nothing and nobody no how. They'd literally have to live with the results.
 
2014-01-04 04:21:11 PM

DerAppie: Snazzy1: WinoRhino: Listening to those people theorize why they lived so long is always a treat.  It's always some backwoods theory on eating a carrot every day, or some weird thing they've done like a brisk walk every night at exactly 2am.

The one lady ate 2 lbs of chocolate a day week...2 lbs!  Now that sounds like a plan to me!

FTFY


Right you are...still, that's a lot!
 
2014-01-04 04:59:24 PM

Snazzy1: DerAppie: Snazzy1: WinoRhino: Listening to those people theorize why they lived so long is always a treat.  It's always some backwoods theory on eating a carrot every day, or some weird thing they've done like a brisk walk every night at exactly 2am.

The one lady ate 2 lbs of chocolate a day week...2 lbs!  Now that sounds like a plan to me!

FTFY

Right you are...still, that's a lot!


Yeah, I think I'm going to follow that diet. But only with chocolate with a high cocoa content.
 
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