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(Medium)   Imagining the post-antibiotics future. It ain't pretty   (medium.com) divider line 112
    More: Scary, farming, antibiotics, Rockaway Beach, nobel prize in medicine, hip replacements, medical journals, penicillins, work accident  
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9780 clicks; posted to Main » on 21 Nov 2013 at 1:43 AM (21 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2013-11-21 01:10:20 AM
Start making friends with some Russians.
 
2013-11-21 01:52:23 AM
*imagines*

So... a lot more regular vaccinations against a wider array of markers than just viral ones, probably heavily subsidized by the government, and slightly stricter enforcement of existing quality control rules in hospitals that sometimes are currently laxly enforced.  Probably the regulators will let up on all the arbitrary barriers for phage treatments, too.

Sure, a bit annoying, but not exactly mind-numbingly terrifying.  99.9% of current antibiotic use isn't strictly necessary anyhow, there are plenty of alternatives, and pretty much every disease of real concern is viral anyhow.

... oh, wait, sorry, I was supposed to be ignorant of basic medical science and thus panicking?  I mean we're all gonna die or whatever, truly the "journalist" with a degree that didn't even require him to take algebra 1 has opened my eyes to a deep and obscure scientific truth which he totally understands the details of.
 
2013-11-21 01:53:59 AM
If modern medicine will be obsolete in the future, then it would be the time for the return of the quack doctors.
 
2013-11-21 01:56:40 AM
this is why I eat dirt

mmmmm.....dirt!
 
2013-11-21 01:56:49 AM
resistant strains are likely caused in part from the abuse of the drugs (not administered or taken properly)

http://www.mayoclinic.com/health/antibiotics/FL00075
 
2013-11-21 01:57:29 AM

Cagey B: Start making friends with some Russians.


While it's a wonderfully clever idea, the finances and time it would take to create a phage - not to mention the logistics behind keeping updated banks of them, since you can't exactly connect them to a central server for updates like your antivirus - make mass uptake a little tricky.

Of course, from where I'm sitting, we don't exactly have a wealth of options or time here...
 
2013-11-21 01:57:38 AM

harrydorcas: If modern medicine will be obsolete in the future, then it would be the time for the return of the quack doctors.


This.

Is.

SEWIOUS.
 
2013-11-21 01:58:57 AM

Victoly: harrydorcas: If modern medicine will be obsolete in the future, then it would be the time for the return of the quack doctors.

This.

Is.

SEWIOUS.


Yeah, it is.
 
2013-11-21 02:00:44 AM
I think we should just keep acting foolish and hope for the best.
 
2013-11-21 02:01:07 AM
Your turn, biotech. Where the fark are the nanobots we inject that just auto-target cancer/aids/gonnasyphaherp?
 
2013-11-21 02:01:24 AM
If man is still alive
If woman can survive
 
2013-11-21 02:04:48 AM
Thank you for tonight's nightmare.
 
2013-11-21 02:09:58 AM
WE'RE ALL GONNA DIE!
 
2013-11-21 02:13:37 AM
img2.timeinc.net
 
2013-11-21 02:14:05 AM
Judging from the picture at the top it seems a post-antibiotic future will consist of being gang raped on the subway.
 
2013-11-21 02:18:29 AM

fusillade762: Judging from the picture at the top it seems a post-antibiotic future will consist of being gang raped on the subway.


So, modern-day India?


/so sorry
//not really
 
2013-11-21 02:18:34 AM
I blame the agricultural industry.

IF YOU DON'T WANT LIVESTOCK TO CATCH BUGS, THEN PUT THEM IN SANITARY CONDITIONS
 
2013-11-21 02:23:38 AM
Every century or two, there is a culling of the human herd. Maybe this will be how the next one will occur.
 
2013-11-21 02:26:37 AM
"Post anti-biotic future" is a hyperbolic phrase intended to incite people to fear, like "Global Warming".

No, this is "selective medical treatment adjustment" brought about by the natural cycles of earth's organisms, and certainly not man-made.

Just like "climate change", "treatment adjustment" is a good thing. Relax, citizen. Sleep. Spend.
 
2013-11-21 02:26:40 AM
 
2013-11-21 02:37:36 AM
I'm sure that with all the talk of getting rid of patents and profit based peer reviewed scientific journals, that plucky researchers who are doing it "for exposure" rather than "for the $$$" will step in and save us.
 
2013-11-21 02:39:17 AM
Farmers... is there nothing they can't screw up?
- Drinking waters polluted by pesticides
- eutrophic streams and lakes due to nutrient rich run-off
- nitrogen deposition changing ecosystems
- multi resistant bacteria due to growth focused use of antibiotics

I'm not saying let's go all organic, but using a bit of common sense will avoid disasters.
Common sense just isn't being applied in this particular industry.
 
2013-11-21 02:46:30 AM
2.bp.blogspot.com

www.livingfoodslifestyle.co.nz
 
2013-11-21 02:47:18 AM
In mid December of last year, while traveling to one of the far reaches of the planet, I came down with a very serious infection. I was on a ship in the South Pacific, near Nuku Hiva. The ship's doctors started running tests on me and quickly ascertained that my white bloodcell count was rapidly rising, from infection, but due to the lack of resources on the ship, they couldn't diagnose me. What they did say was downright frightening: "If you don't get to a hospital in the next 48 hours, you'll likely die."

We were still 6 days to sail to get back to the USA.

I was pumped full of IV antibiotic Cipro, along with morphine and medically evacuated by lifeboat to the island of Nuke Hiva. Other than Antarctica or Easter Island, this is one of the most remote spots on Earth. So sparsely populated, they don't have a veterinary clinic, let alone a hospital. They only get one flight a day, in and out, to Tahiti - which was 1,500 miles away.

To make a long story short, I made it to the hospital in Tahiti, while descending into septic shock. There they were able to continue my heavy antibiotic regimen with cipro, but were unable to get the diagnostic equipment,. After a week, the US State department and embassy stepped in, and Air France evac'd me back to the USA for emergency surgery. The doctors beck in the states were amazed that I survived as long as I had, attributing my survival completely on the heavy & steady dose of antibiotics.

Thankfully they still work for me. I have a feeling that in my lifetime, I'll see a number of my friends die from resistant bacteria.

/last month a scuba buddy was hospitalized for MRSA.
//and trust me, you never want to fall ill in the South Pacific . . .
 
2013-11-21 02:47:28 AM
Humans have been weakening themselves for years... Insulin injections, surgery for those who would otherwise not be able to have children. You are all idiots.

NEANDERTHALS SHALL RISE AGAIN!!!

Die you morans!
 
2013-11-21 02:49:10 AM

Fista-Phobia: [2.bp.blogspot.com image 220x220]

[www.livingfoodslifestyle.co.nz image 292x219]


Add a little red food coloring and you'll have yourself some lava for a volcano.
 
2013-11-21 02:53:11 AM
Mankind will face some serious hardships soon. Such is life.
 
2013-11-21 02:56:25 AM

Public Savant: Farmers... is there nothing they can't screw up?
- Drinking waters polluted by pesticides
- eutrophic streams and lakes due to nutrient rich run-off
- nitrogen deposition changing ecosystems
- multi resistant bacteria due to growth focused use of antibiotics

I'm not saying let's go all organic, but using a bit of common sense will avoid disasters.
Common sense just isn't being applied in this particular industry.


Agreed. Granted, this is also an economic issue having to do with the amount of food a given farm has to produce if it will be profitable at all. You have smaller commercial farmers competing against the giants who actually set the prices. And of course, we the consumers pay one way or another. Over the long term, it would be better to pay more for food now, rather than for more medical care and/or funerals later. Call it insurance.

But try telling that to ConAgra and Tyson.

Of course, there are also your small, local farms that don't necessarily engage in detrimental practices like the blanket use of antibiotics. Those farms are not necessarily profitable or even run for profit. They may be for the purpose of protecting heritage breed animals. They may be just for fun. It varies. But they're not producing commercial levels of food.

There's a middle ground somewhere, but there are no easy solutions, unfortunately.
 
2013-11-21 02:57:03 AM

Atomic Spunk: Fista-Phobia: [2.bp.blogspot.com image 220x220]

[www.livingfoodslifestyle.co.nz image 292x219]

Add a little red food coloring and you'll have yourself some lava for a volcano.


A salvecano!
 
2013-11-21 03:06:47 AM
Soon, soon you'll all come crawling to homeopathic doctors, begging to be cured, faces filled with shame and regret for the way you laughed at us. Us who will in the not to distant future become the saviors of mankind.
 
2013-11-21 03:07:21 AM
I recently lost my left leg to a drug resistant infection. Got scratched on Tuesday, and by Saturday night the docs told me to lose the leg or die. Happened just that fast. The sad part was I had turned 21 just two months earlier.

/I'm still hopping mad about the whole ordeal.
//Had about a jilliondy people tell me to dress up as a pirate last Halloween.
///Wish I'd thought of that.
 
2013-11-21 03:18:17 AM

Jim_Callahan: *imagines*

So... a lot more regular vaccinations against a wider array of markers than just viral ones, probably heavily subsidized by the government, and slightly stricter enforcement of existing quality control rules in hospitals that sometimes are currently laxly enforced.  Probably the regulators will let up on all the arbitrary barriers for phage treatments, too.

Sure, a bit annoying, but not exactly mind-numbingly terrifying.  99.9% of current antibiotic use isn't strictly necessary anyhow, there are plenty of alternatives, and pretty much every disease of real concern is viral anyhow.

... oh, wait, sorry, I was supposed to be ignorant of basic medical science and thus panicking?  I mean we're all gonna die or whatever, truly the "journalist" with a degree that didn't even require him to take algebra 1 has opened my eyes to a deep and obscure scientific truth which he totally understands the details of.


Article cites lots of doctors, and explains how antibiotics are critical to major treatments such as burns, chemotherapy and organ transplant. But I should just take some guy's word on the Internet that this is rubbish, because something about journalists being unable to math.
 
2013-11-21 03:19:03 AM
I've been warning people about this since the 90s, though I'm not exactly pleased to have been proven right. Every doctor I know still just throws antibiotics at sick people merely because it's de rigueur. Overprescription of antibiotics, low-dose antibiotics in cattle to keep them healthier and thus heavier and more profitable, and much of the rest of the world allowing people to get them over-the-counter and then not taking the full course once they "feel better" in order to save them for future illness; all of these have led to the rise of resistant strains. Not to mention that despite the veritable shiatloads of money spent on new drug development, research into new antibiotic agents is lagging way behind need. Is the next seriously virulent pandemic gonna be something we could have corralled easily 100 years ago?
 
2013-11-21 03:36:21 AM

Bonanza Jellybean: I've been warning people about this since the 90s, though I'm not exactly pleased to have been proven right. Every doctor I know still just throws antibiotics at sick people merely because it's de rigueur. Overprescription of antibiotics, low-dose antibiotics in cattle to keep them healthier and thus heavier and more profitable, and much of the rest of the world allowing people to get them over-the-counter and then not taking the full course once they "feel better" in order to save them for future illness; all of these have led to the rise of resistant strains. Not to mention that despite the veritable shiatloads of money spent on new drug development, research into new antibiotic agents is lagging way behind need. Is the next seriously virulent pandemic gonna be something we could have corralled easily 100 years ago?


"What do you mean, I/my child/my family 'just have a cold' and there's nothing you can do?! I paid you good money! I want some antibiotics, and if you don't give me some, I'll find a doctor who will!"
--sigh, okay, here's some amoxicillin, but be sure you finish the whole bottle.

SIX MONTHS LATER

"What do you mean, I/my child/my family 'just has the flu' and there's nothing you can do?!? Wait, I still have half the bottle of that pink stuff you gave us last time, would that do any good??"
--but I told you...never mind...(thinks: I should have gone into real estate like mother wanted me to)

A YEAR LATER

"What do you mean I/my child/my family has 'drug-resistant staph' and have to check into a hospital!?! Isn't there anything else you can do?!? What about all those half-empty bottles of pills you keep prescribing, won't those help?!?"
 
2013-11-21 03:46:01 AM

Bonanza Jellybean: Is the next seriously virulent pandemic gonna be something we could have corralled easily 100 years ago?


Dude, FAIL!
 
2013-11-21 03:49:30 AM

Twinkles: Bonanza Jellybean: Is the next seriously virulent pandemic gonna be something we could have corralled easily 100 years ago?

Dude, FAIL!


No, dude, you fail.

virulent [ˈvɪrʊlənt]adj
1. (Medicine / Pathology)
a.  (of a microorganism) extremely infective
b.  (of a disease) having a rapid course and violent effect
2. extremely poisonous, injurious, etc.
3. extremely bitter, hostile, etc.

"Virulent" has nothing to do with "virus".
 
2013-11-21 03:55:16 AM
Got cellulitis? Take some keflex. Not working? You probably have CA-MRSA, take some bactrim. Not working? Try clindamycin OR doxycycline instead. Better run that d-zone test at the lab and eat a fark-ton of Activia though.

Got CA-Pneumonia? 1g Ceftriaxone q24h. Then throw your antipseudomonal in there if you're going off to the ICU- so we'll throw in some levaquin 750mg IV qd. What's that, flouroquinalones have the highest resistance rates emerging in hospital according to your institutional bug report? Guess you could do gentamycin instead, that 7mg/kg shiat. Oh, but wait, the lab cultures say it's MRSA? SHOULDA DONE VANCO!!! Throw some Vancomycin 15/mg/kg at her q8/12/24h depending on renal clearance, and then draw a troft before the 5th dose! Just keep that stuff between 15-20mcg/mL plasma concentration. What? resistant to vancomycin? Go for the zosyn!!! Still nada? Dear god we're doomed.

I guess what i'm trying to say is even if we developed a whole new class of antibiotics, it would take another 10 years after entering the marketplace before we would find a suitable place to use it in the guidelines. EBM has it's perks for pulling out efficient and effective use, but that stuff takes time to develop.
 
2013-11-21 03:59:27 AM

Twinkles: Bonanza Jellybean: Is the next seriously virulent pandemic gonna be something we could have corralled easily 100 years ago?

Dude, FAIL!


Holy crap- this has the potential to be the next "NIXON YOU DOLT!"
 
2013-11-21 04:20:40 AM

Modern Apothecary PharmD: Got cellulitis? Take some keflex. Not working? You probably have CA-MRSA, take some bactrim. Not working? Try clindamycin OR doxycycline instead. Better run that d-zone test at the lab and eat a fark-ton of Activia though.

Got CA-Pneumonia? 1g Ceftriaxone q24h. Then throw your antipseudomonal in there if you're going off to the ICU- so we'll throw in some levaquin 750mg IV qd. What's that, flouroquinalones have the highest resistance rates emerging in hospital according to your institutional bug report? Guess you could do gentamycin instead, that 7mg/kg shiat. Oh, but wait, the lab cultures say it's MRSA? SHOULDA DONE VANCO!!! Throw some Vancomycin 15/mg/kg at her q8/12/24h depending on renal clearance, and then draw a troft before the 5th dose! Just keep that stuff between 15-20mcg/mL plasma concentration. What? resistant to vancomycin? Go for the zosyn!!! Still nada? Dear god we're doomed.

I guess what i'm trying to say is even if we developed a whole new class of antibiotics, it would take another 10 years after entering the marketplace before we would find a suitable place to use it in the guidelines. EBM has it's perks for pulling out efficient and effective use, but that stuff takes time to develop.


Apparently I haven't been on antibiotics in forever. The only thing I recognized there was doxysomething which I think I took in an extra low dose for rosacea, too low to cause resistance (I think).
 
2013-11-21 04:44:40 AM
You really only should get an antibiotic prescription upon evidence of an actual serious infection that your body is having difficulty fighting.  Something like pneumonia or a worsening case of bronchitis that's likely to progress into pneumonia.  Or when a post-trauma/post-surgery infection becomes serious.

No more of this I have the sniffles so I demand antibiotics stuff.

Really, let's legalize cocaine and psilocybin, and put amoxicillin onto Schedule II.
 
2013-11-21 04:52:46 AM
I'll wait until I get Jenny McCarthy's opinion on this.
 
2013-11-21 05:04:47 AM

relaxitsjustme: Soon, soon you'll all come crawling to homeopathic doctors, begging to be cured, faces filled with shame and regret for the way you laughed at us. Us who will in the not to distant future become the saviors of mankind.


please, just let the infection run the course and kill me.
 
2013-11-21 05:06:11 AM
Don't get sick. It's really the only solution.
 
2013-11-21 05:10:02 AM

Victoly: harrydorcas: If modern medicine will be obsolete in the future, then it would be the time for the return of the quack doctors.

This.

Is.

SEWIOUS.


Wonder Pets is now required viewing for Fark readers?
 
2013-11-21 05:29:21 AM
Antibiotics will always work on me because I don't believe in evolution.
 
2013-11-21 05:47:13 AM

super_grass: I blame the agricultural industry.

IF YOU DON'T WANT LIVESTOCK TO CATCH BUGS, THEN PUT THEM IN SANITARY CONDITIONS


This, then learn to live with a little loss in your investment.
 
2013-11-21 05:47:39 AM

MayoSlather: Antibiotics will always work on me because I don't believe in evolution.


It's not that people "don't believe" is just that evolution is misapplied or misunderstood.

Resistant bacteria are bound to happen given the reproduction rate and endless resources.  They're not actually adapting to the drugs themselves.  That's kind of a creationist line of thought.

Killing off the non resistant stuff has nothing to do with it.  They're not exactly competing for resources, on scale resources are limitless.  There's no natural balance that we're affecting by using anti-biotics, one does not crowd the other out.  The resistant strains are not filling in where resources are more abundant, they're living peaceably beside the other strains.

What is different in modern times is that man travels much more than he used to, sees more people in a given day, week, year.

These bugs that become resistant due to natural evolution(inevitable) now have a greater ability to spread, as do the more treatable bugs.

It's like blaming more polar bears on the fact that I use rat poison to kill the rats in my garage.  No, the polar bears, whether they thrive or not, are irrlevant to the rat population half way around the globe.

It's a mass delusion of people who thrive on fear and seek to find blame.  Kind of like boobs causing earthquakes.
 
2013-11-21 06:02:17 AM

rkiller1: [img2.timeinc.net image 612x380]


Wait, Lori got zombified? When did this happen?

/has decided to enjoy the bread and circuses and not worry about the apocalypse
//although 'enjoy' is debatable where Days of our Zombies is concerned
 
2013-11-21 06:39:57 AM
Yes it's going to suck hard, but at least we'll get a little bit of natural selection going again.

//Mother nature is a cruel, evil woman
//She makes Pat Buchanan look like Ralph Nader
 
2013-11-21 06:44:16 AM
That is one long-ass article.
 
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