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(Real Clear Science)   New drug effective against Type 2 diabetes & obesity, tentatively named EXERCISE   (realclearscience.com) divider line 80
    More: Interesting, exercises, insulin sensitivity, Anti-diabetic medication, obesity, diabetes  
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4430 clicks; posted to Main » on 05 Nov 2013 at 9:59 AM (23 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2013-11-05 10:01:23 AM
WHERE DO I INJECT THIS "exercise" YOU SPEAK OF???
 
2013-11-05 10:02:22 AM
Can I get "exercise" in a pill?
 
2013-11-05 10:02:49 AM
Like getting really cold ice cream out of a container? I think I am getting stronger, I bent a spoon last week.
 
2013-11-05 10:02:52 AM

lesliessexxy: WHERE DO I INJECT THIS "exercise" YOU SPEAK OF???


IN YOUR VAGINA BY WHICH I MEAN YOUR VAGINA, IF YOU KNOW WHAT I MEAN.


/penis
 
2013-11-05 10:05:53 AM

Yakk: Like getting really cold ice cream out of a container? I think I am getting stronger, I bent a spoon last week.


I read a few weeks ago here on Fark that if you eat cold food, you will burn more calories since your body needs to maintain a steady temperature. So keep eating that ice cream.
 
2013-11-05 10:06:05 AM
You guys mock, but if TFA is correct, this is a big farking deal. They already did some human testing, and even though the results are very limited, they're pretty damn significant.
 
2013-11-05 10:06:47 AM
Put down the donuts, fatty.

It's genetics that makes me weigh 350.

A little exercise goes a long way.

Stop fat shaming me, I just have slow metabolism.
 
2013-11-05 10:07:04 AM
In before all the "my fad diet is superior to exercise" comments.
 
2013-11-05 10:08:46 AM
One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS
 
2013-11-05 10:10:44 AM
Subby's headline made me giggle.


/It's funny because it's true!
 
2013-11-05 10:10:56 AM

Aidan: You guys mock, but if TFA is correct, this is a big farking deal. They already did some human testing, and even though the results are very limited, they're pretty damn significant.


Of course, it's probably worth reviewing the Avandia debacle first.  Glaxo just paid out a $3 Billion "Oops, our bad" fine for their FDA-approved anti-diabetes medication.

You're trying to modulate a core metabolic function here, and it's easy to end up with some pretty nasty unintended consequences.
 
2013-11-05 10:11:08 AM

MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS


Here.....
 
img5.hvg.hu
 
2013-11-05 10:11:21 AM

Aidan: You guys mock, but if TFA is correct, this is a big farking deal. They already did some human testing, and even though the results are very limited, they're pretty damn significant.


Pffft, clinically tested pill that cures diabetes and kills fat with no side effects already past stage-1 trials.  What a joke.  That'd be like living in the future.
//I'd take it.  It's like a cheat-code for real life.
 
2013-11-05 10:13:40 AM

ChipNASA: lesliessexxy: WHERE DO I INJECT THIS "exercise" YOU SPEAK OF???

IN YOUR VAGINA BY WHICH I MEAN YOUR VAGINA, IF YOU KNOW WHAT I MEAN.


/penis


I'LL TAKE TWO EXERCISES PLEASE!

/vagina
 
2013-11-05 10:16:36 AM
Developed at IU? Gee, where did they find the test subjects?

<snicker>
 
2013-11-05 10:16:52 AM

lesliessexxy: ChipNASA: lesliessexxy: WHERE DO I INJECT THIS "exercise" YOU SPEAK OF???

IN YOUR VAGINA BY WHICH I MEAN YOUR VAGINA, IF YOU KNOW WHAT I MEAN.


/penis

I'LL TAKE TWO EXERCISES PLEASE!

/vagina


Well, this just got interesting.

/grabs popcorn
//likes popcorn while watching exercise
 
2013-11-05 10:19:14 AM
25.media.tumblr.com

24.media.tumblr.com

almost.thedoctorschannel.com
 
2013-11-05 10:19:14 AM

Farkn Yaj Yenrac: Put down the donuts, fatty.

It's genetics that makes me weigh 350.

A little exercise goes a long way.

Stop fat shaming me, I just have slow metabolism.


Dont forget big boned and you have a thyroid problem, trust me I know what you are going through.  I use to be able to swallow chicken nuggets whole then my thyroid started to swell and now I have to chew to eat them.....the extra effort almost isn't worth it.
 
2013-11-05 10:23:23 AM

MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS


Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.
 
2013-11-05 10:25:41 AM
We see articles like this every now and again, an easy cure for obesity. Each one somehow slips into the void with no fanfare. I suspect some bizarre and terrible side effect is discovered like penis hemorrhages and anemia or something along those lines. It seems likely that this one will follow suit.
 
2013-11-05 10:25:58 AM
raw.github.com
 
2013-11-05 10:26:32 AM
Is it fen-phen.
 
2013-11-05 10:26:44 AM

MyRandomName: MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS

Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.


This has been another rousing edition of "You're both right!"

Thanks for playing.
 
2013-11-05 10:26:46 AM

gizmokid18: Farkn Yaj Yenrac: Put down the donuts, fatty.

It's genetics that makes me weigh 350.

A little exercise goes a long way.

Stop fat shaming me, I just have slow metabolism.

Dont forget big boned and you have a thyroid problem, trust me I know what you are going through.  I use to be able to swallow chicken nuggets whole then my thyroid started to swell and now I have to chew to eat them.....the extra effort almost isn't worth it.


I actually do have a thyroid problem.  :(

It didn't make me fat, but it sure as hell makes it hard to drop weight.
 
2013-11-05 10:28:08 AM

busy chillin': MyRandomName: MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS

Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.

This has been another rousing edition of "You're both right!"

Thanks for playing.


Except for the fact that the Boobieser made a strawman argument that nobody is making. Nobody claimed non obese people couldn't get diabetes.
 
2013-11-05 10:29:48 AM
MyRandomName:

Except for the fact that the Boobieser made a strawman argument that nobody is making. Nobody claimed non obese people couldn't get diabetes.

THEM DANGED OL' BOOBIESERs!

/filter lovvvvvve
 
2013-11-05 10:30:20 AM

MyRandomName: MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS

Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.


I think most of them are made up on the spot

/statistically
//so I'm defensive about being diabetic... what can I say?
 
2013-11-05 10:38:02 AM

MaudlinMutantMollusk: MyRandomName: MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS

Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.

I think most of them are made up on the spot

/statistically
//so I'm defensive about being diabetic... what can I say?


Are you T1 or T2?
 
2013-11-05 10:42:00 AM

JohnnyCanuck: MaudlinMutantMollusk: MyRandomName: MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS

Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.

I think most of them are made up on the spot

/statistically
//so I'm defensive about being diabetic... what can I say?

Are you T1 or T2?


Type 2

/I think genetics may be a factor, but a number of Fark health experts have told me that's impossible
 
2013-11-05 10:46:26 AM
Can you really effectively manage/treat diabetes with exercise?
 
2013-11-05 10:51:42 AM

MaudlinMutantMollusk: JohnnyCanuck: MaudlinMutantMollusk: MyRandomName: MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS

Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.

I think most of them are made up on the spot

/statistically
//so I'm defensive about being diabetic... what can I say?

Are you T1 or T2?

Type 2

/I think genetics may be a factor, but a number of Fark health experts have told me that's impossible


I've been introduced to the idea of "because". Why does this person have T2 diabetes? Because. Don't fit the typical model for a sufferer of T2 diabetes? Tough titties, you still have the problem to deal with.
 
2013-11-05 10:52:19 AM
I'm hypoglycemic so I'm getting a kick out of this thread
 
2013-11-05 10:52:29 AM

belhade: Can you really effectively manage/treat diabetes with exercise?


Yes. Studies show 120 minutes of exercise a week in any increments can reduce blood glucose levels and if done for at least 6 months will reduce A1C levels. That combined with a low sugar and low carb diet can effectively treat Type 2 diabetes in most people.

That 120 minutes of exercise does not need to be all at once, it can be 10 minutes here, 10 minutes there, all you need to do is make a concerted effort.
 
2013-11-05 10:52:35 AM

MaudlinMutantMollusk: JohnnyCanuck: MaudlinMutantMollusk: MyRandomName: MaudlinMutantMollusk: One more time for those who missed it: you don't have to be fat to get diabetes

/I'm 6 foot and weigh 177, FFS

Statistics. How do they work. A significant number of people with diabetes gained it through their own lifestyle choices.

I think most of them are made up on the spot

/statistically
//so I'm defensive about being diabetic... what can I say?

Are you T1 or T2?

Type 2

/I think genetics may be a factor, but a number of Fark health experts have told me that's impossible


At least some people understand that their are different types of diabetes which have next to nothing to do with each other. My son was diagnosed with type 1 or "juvenile" diabetes at 18 months. 4 shots a day for every day of his life. I had this HUGE mother of one of the kids at his school try to tell me his diet was what caused it. I asked if she had diabetes and when she said no I told her she just proved herself wrong and left it at that.

/csb
 
2013-11-05 10:55:42 AM

Slaves2Darkness: belhade: Can you really effectively manage/treat diabetes with exercise?

Yes. Studies show 120 minutes of exercise a week in any increments can reduce blood glucose levels and if done for at least 6 months will reduce A1C levels. That combined with a low sugar and low carb diet can effectively treat Type 2 diabetes in most people.

That 120 minutes of exercise does not need to be all at once, it can be 10 minutes here, 10 minutes there, all you need to do is make a concerted effort.


So what you're saying is I should make my wife get on top.
 
2013-11-05 10:56:59 AM

belhade: Can you really effectively manage/treat diabetes with exercise?


Yes and no. Depends on many factors. Some Type 2 can manage with exercise and diet. But typically those T2 who can are diabetic because of poor choices with regard to diet & exercise in the first place.

Most T2 need at least oral meds. Some need insulin.
All T1 need at least insulin.

All diabetics regardless of type should subscribe to a well regulated diet and exercise regime.

A small percentage of T2 developed diabetes due to poor habits. Most cases are genetics.
 
2013-11-05 11:01:04 AM
"Ask your doctor if getting off your ass and exercising is right for YOU"
 
2013-11-05 11:09:47 AM
Meh. Somebody's been mucking about in Human Genetics. Fat is one thing, but Wal-Mart people are  clearly genetic experiments. Article is intended to make readers ignore the facts.
 
2013-11-05 11:11:17 AM

Slaves2Darkness: belhade: Can you really effectively manage/treat diabetes with exercise?

Yes. Studies show 120 minutes of exercise a week in any increments can reduce blood glucose levels and if done for at least 6 months will reduce A1C levels. That combined with a low sugar and low carb diet can effectively treat Type 2 diabetes in most people.

That 120 minutes of exercise does not need to be all at once, it can be 10 minutes here, 10 minutes there, all you need to do is make a concerted effort.


I can sneak in 15-20 minutes of walking each day at work. Instead of several smoke breaks throughout the day, I take several 5 minute walking breaks around the office. Later after work I take the dog for a 20 minute walk, so that's an easy 30+ minutes of mindless exercise in a day.

I don't actually smoke but I argued that if other people are permitted to go outdoors 6 times a day to smoke, I should be allowed to go outside as well.
 
2013-11-05 11:15:37 AM

chimp_ninja: Aidan: You guys mock, but if TFA is correct, this is a big farking deal. They already did some human testing, and even though the results are very limited, they're pretty damn significant.

Of course, it's probably worth reviewing the Avandia debacle first.  Glaxo just paid out a $3 Billion "Oops, our bad" fine for their FDA-approved anti-diabetes medication.

You're trying to modulate a core metabolic function here, and it's easy to end up with some pretty nasty unintended consequences.


Oh believe me, I know. I take synthroid. :P
 
2013-11-05 11:18:22 AM

cgraves67: We see articles like this every now and again, an easy cure for obesity. Each one somehow slips into the void with no fanfare. I suspect some bizarre and terrible side effect is discovered like penis hemorrhages and anemia or something along those lines. It seems likely that this one will follow suit.


I've had borderline diabetes for years. I'm obese, lift weights and eat a balanced diet. My blood sugar's all over the map, and "normal" diabetes drugs like Byetta give me horrible medine-induced pancreatitis. I've been on a new class of drug, an SGLT2-inhibitor called Invokana, since June. It does one simple thing: it prevents sugar that arrives in your kidneys from being reabsorbed into your bloodstream (it's dumped directly into your bladder in your urine). This has easily tripled my weight loss rate, and I'm now at my lowest weight in 30 years.

I hesitate to use the term "miracle drug" but this drug has really made a huge positive difference in my life.
 
2013-11-05 11:19:48 AM

belhade: Slaves2Darkness: belhade: Can you really effectively manage/treat diabetes with exercise?

Yes. Studies show 120 minutes of exercise a week in any increments can reduce blood glucose levels and if done for at least 6 months will reduce A1C levels. That combined with a low sugar and low carb diet can effectively treat Type 2 diabetes in most people.

That 120 minutes of exercise does not need to be all at once, it can be 10 minutes here, 10 minutes there, all you need to do is make a concerted effort.

So what you're saying is I should make my wife get on top.


Does she have big tits? If yes, then yes, you should.
 
2013-11-05 11:28:41 AM
State funded university
Drugs
1st trials done in only six weeks
No serious side effects =
Ninety new commercials an hour telling me to take more drugs while I try to keep my kids off them and 200 new commercials of why I need a lawyer to get me justice.

Fark just give me the meth.
 
2013-11-05 11:31:17 AM

elysive: In before all the "my fad diet is superior to exercise" comments.


In general, a bad diet is a larger contributing factor to obesity than lack of exercise, although both are important.  Unless you have hours of free time every available to you every day, you'll never exercise away those donuts, steak bomb, Big Max Extra Value Meal and that half a bag of chips you eat every day.
 
2013-11-05 11:31:33 AM

xoxo: Slaves2Darkness: belhade: Can you really effectively manage/treat diabetes with exercise?

Yes. Studies show 120 minutes of exercise a week in any increments can reduce blood glucose levels and if done for at least 6 months will reduce A1C levels. That combined with a low sugar and low carb diet can effectively treat Type 2 diabetes in most people.

That 120 minutes of exercise does not need to be all at once, it can be 10 minutes here, 10 minutes there, all you need to do is make a concerted effort.

I can sneak in 15-20 minutes of walking each day at work. Instead of several smoke breaks throughout the day, I take several 5 minute walking breaks around the office. Later after work I take the dog for a 20 minute walk, so that's an easy 30+ minutes of mindless exercise in a day.

I don't actually smoke but I argued that if other people are permitted to go outdoors 6 times a day to smoke, I should be allowed to go outside as well.


My doctor told me that walking golf 3-4 times a week at 1 1/2 hrs a time carrying a bag 3 miles each time does not count because heart rate does not go high enough. That pissed me off.
 
2013-11-05 11:32:21 AM

Persnickety: elysive: In before all the "my fad diet is superior to exercise" comments.

In general, a bad diet is a larger contributing factor to obesity than lack of exercise, although both are important.  Unless you have hours of free time every available to you every day, you'll never exercise away those donuts, steak bomb, Big Max Extra Value Meal and that half a bag of chips you eat every day.


Max = Mac - damn auto correct.
 
2013-11-05 11:43:47 AM
I think my mother is on this drug (which they dont mention the name of) as part of the trials.  She injects it once a week.  It knocks her out for the day practically and kills her appetite with some mild nausea.  She has lost a lot of weight in the short time she has been on it and her blood sugar is the lowest its been in decades.  She loves it to death, and if this keeps up she might be off insulin by the end of the year.  Read that last part again, ok read it again and again a few more times.  This new drug, WILL NEVER EVER IN A farkING BILLION YEARS BE ALLOWED ON THE OPEN MARKET!  Big Pharma makes hundreds of billions a year on insulin, its one of their biggest money makers in the world, surpassing even viagra as a cash cow.  They will never, ever allow it to be stopped.

I told my mother to enjoy it while it last, because it wont last.  We dont cure things any more.  No money in it.


/health and pain management should not be a business.  We are farking ourselves over by allowing it to be.
 
2013-11-05 11:49:46 AM
lesliessexxy:

I'LL TAKE TWO EXERCISES PLEASE!

/vagina


Why do you get to have all the fun?

/anus
 
2013-11-05 12:24:25 PM

orclover: I think my mother is on this drug (which they dont mention the name of) as part of the trials.  She injects it once a week.  It knocks her out for the day practically and kills her appetite with some mild nausea.  She has lost a lot of weight in the short time she has been on it and her blood sugar is the lowest its been in decades.  She loves it to death, and if this keeps up she might be off insulin by the end of the year.  Read that last part again, ok read it again and again a few more times.  This new drug, WILL NEVER EVER IN A farkING BILLION YEARS BE ALLOWED ON THE OPEN MARKET!  Big Pharma makes hundreds of billions a year on insulin, its one of their biggest money makers in the world, surpassing even viagra as a cash cow.  They will never, ever allow it to be stopped.

I told my mother to enjoy it while it last, because it wont last.  We dont cure things any more.  No money in it.


/health and pain management should not be a business.  We are farking ourselves over by allowing it to be.


DNRTA but as long as you have to keep taking this new pill every day, why would big pharma care which medicine you have to buy from them?  If it makes you live longer, that's even more money for them.
 
2013-11-05 12:28:18 PM

orclover: I think my mother is on this drug (which they dont mention the name of) as part of the trials.  She injects it once a week.  It knocks her out for the day practically and kills her appetite with some mild nausea.  She has lost a lot of weight in the short time she has been on it and her blood sugar is the lowest its been in decades.  She loves it to death, and if this keeps up she might be off insulin by the end of the year.  Read that last part again, ok read it again and again a few more times.  This new drug, WILL NEVER EVER IN A farkING BILLION YEARS BE ALLOWED ON THE OPEN MARKET!  Big Pharma makes hundreds of billions a year on insulin, its one of their biggest money makers in the world, surpassing even viagra as a cash cow.  They will never, ever allow it to be stopped.

I told my mother to enjoy it while it last, because it wont last.  We dont cure things any more.  No money in it.


/health and pain management should not be a business.  We are farking ourselves over by allowing it to be.


That's the one thing that's really breaking our society.  The willful withholding of useful technologies and innovations for the sake of prolonging profit on old technologies.  In a healthy market, this shouldn't be allowed to happen.  The only way a capitalist society can truly succeed is if innovation outpaces corruption.  Currently, this doesn't seem to be the case.  The difficulty is forcing the people who create the innovation to actually push their inventions to market.  It would certainly be a fine line to tread but the thing is we've already invented viable solutions to a lot of our problems but they're being held back for the sake of profit.  Though it is hard to make that argument as any society-changing invention is bound to make more money than anything else currently on the market which makes it fairly stupid to withhold any potentially successful innovation.
 
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