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(Science Daily)   Time to updateyour retirement plans Farkers; Researchers have discovered a way to convert fat cells to liver cells   (sciencedaily.com) divider line 21
    More: Spiffy, liver cells, researchers, liver failure, pluripotent stem cells, Stanford University Medical Center, acetaminophen, liposuction, cell type  
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1104 clicks; posted to Geek » on 23 Oct 2013 at 11:55 AM (49 weeks ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



21 Comments   (+0 »)
   
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2013-10-23 11:58:02 AM
10 Drink beer
20 get fat
30 destroy liver
40 convert fat cells to liver cells
50 goto 10
 
2013-10-23 11:59:26 AM
Funny how this announcement coincides with my plans to start a liver transplant source farm.

\drink up, you know we'll be here for you.
 
2013-10-23 12:06:21 PM
Given that the liver can regenerate itself, I wonder if a person could become a partial liver donor in exchange for priority consideration in the event that they need an organ transplant at some later date. Hmm.
 
2013-10-23 12:06:46 PM
I'm going to live forever!
 
2013-10-23 12:13:00 PM
So I'm not really overweight, I've just got plenty of liver reserves.
 
2013-10-23 12:13:34 PM
Acute liver failure from acetaminophen alone takes about 500 lives annually and accounts for close to 60,000 emergency-room visits and more than 25,000 hospitalizations annually.

And remember, this is the drug that's not only still legal, but still being added to hundreds of formulations that have no reason for containing it, including some that include alcohol (and it's alcohol + acetaminophen that kills the liver most quickly and effectively).

Thank GOD we're still mostly protected from weed, though, which is equally damaging to your liver -- if, that is, you surgically excise your liver, then roast it over a burning bale.
 
2013-10-23 12:15:13 PM
It's not a paunch, it's a stem cell storage unit.
 
2013-10-23 12:16:26 PM
Indulgence perpetual motion
 
2013-10-23 12:24:01 PM
What the heck am I gonna do with 17 livers?
 
2013-10-23 12:28:15 PM
Now come up with a way to do that in vivo and cure Fatty Liver disease.
 
2013-10-23 12:33:10 PM

jdetweiler: What the heck am I gonna do with 17 livers?


Fava beans and a nice Chianti?
 
2013-10-23 12:41:42 PM
jfarkinB: And remember, this is the drug that's not only still legal, but still being added to hundreds of formulations that have no reason for containing it, including some that include alcohol (and it's alcohol + acetaminophen that kills the liver most quickly and effectively).

I'm no fan of drugs, but IIRC it's people eating the damn things like candy and ODing that get their livers exploded.

"While generally safe for use at recommended doses (1,000 mg per single dose and up to 4,000 mg per day for adults),[5] even small overdoses can be fatal. The ratio between fatal doses and therapeutic doses (the therapeutic index) is much smaller than for other over-the-counter painkillers.

According to the US Food and Drug Administration as little as 25 percent above the maximum daily dose can cause liver damage when taken over several days.[6] Acute overdoses of paracetamol can cause potentially fatal liver damage. The risk may be heightened by chronic alcohol abuse. Paracetamol toxicity is the foremost cause of acute liver failure in the Western world, and accounts for most drug overdoses in the United States, the United Kingdom, Australia and New Zealand.[7][8][9][10] In the United States, over 150 people die each year from overdoses, with up to 78,000 emergency room visits.[6]"
 
2013-10-23 12:43:56 PM

GRCooper: I'm going to liver forever!


FIFY.
 
2013-10-23 01:00:20 PM
Well, screw you diet, I'm gonna drink myself thin!
 
2013-10-23 01:07:04 PM
so, with this whole fatty liver thing, i've got a head start?
 
2013-10-23 01:07:51 PM
good by liposuction, hello hepatectomy!
 
2013-10-23 01:16:45 PM
So, they repatented hanging drop cultures?

/don't take acetaminophen if I can avoid it, I don't think it's a good thing at any dose.
 
2013-10-23 07:27:08 PM

lordargent: jfarkinB: And remember, this is the drug that's not only still legal, but still being added to hundreds of formulations that have no reason for containing it, including some that include alcohol (and it's alcohol + acetaminophen that kills the liver most quickly and effectively).

I'm no fan of drugs, but IIRC it's people eating the damn things like candy and ODing that get their livers exploded.

"While generally safe for use at recommended doses (1,000 mg per single dose and up to 4,000 mg per day for adults),[5] even small overdoses can be fatal. The ratio between fatal doses and therapeutic doses (the therapeutic index) is much smaller than for other over-the-counter painkillers.

According to the US Food and Drug Administration as little as 25 percent above the maximum daily dose can cause liver damage when taken over several days.[6] Acute overdoses of paracetamol can cause potentially fatal liver damage. The risk may be heightened by chronic alcohol abuse. Paracetamol toxicity is the foremost cause of acute liver failure in the Western world, and accounts for most drug overdoses in the United States, the United Kingdom, Australia and New Zealand.[7][8][9][10] In the United States, over 150 people die each year from overdoses, with up to 78,000 emergency room visits.[6]"


Given how dangerous paracetamol is I am baffled as to why codeine is so heavily restricted while paracetamol is available with no script.
 
2013-10-24 03:27:02 AM
kg2095: Given how dangerous paracetamol is I am baffled as to why codeine is so heavily restricted while paracetamol is available with no script.

AFAIK, people get high on codeine and if it were sold OTC, more people would die of ODs from it.

// I'm firmly in the 'drugs are bad' camp, so I avoid them. But I'm also fairly liberal, so if people want blow their livers and/or minds with excessive doses, have at it (as long as they don't screw with anyone else in the process.).

// I'm also fairly draconian, so if someone does happen to blow their liver because they took more than the recommended dosages, well fark them, it told you the limit right there on the packaging.
 
2013-10-24 01:12:40 PM
I'm not fat, I'm big <strike>boned</strike> livered.
 
2013-10-24 01:14:10 PM
Well, that didn't go as planned...
 
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