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(Venture Beat)   Want to use a personal genomics service without giving up your privacy? Here's a step-by-step guide   (venturebeat.com) divider line 6
    More: Interesting, personal genomics, data breaches, customer support, Alzheimer's Disease, testing kit, nucleotides, institutional review board, genetic code  
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745 clicks; posted to Geek » on 09 Oct 2013 at 10:01 AM (1 year ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



6 Comments   (+0 »)
   
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2013-10-09 10:29:37 AM  
"How about how likely you are to get Alzheimers or how fast your body processes caffeine? All of these clues are in your genes"

Or I could just drink a coffee and use a watch? I could just look up my family tree? What problem is this thing solving?
 
2013-10-09 10:43:30 AM  
I ordered one of these kits recently and used some of the measures mentioned... registered my account with a pseudonym using a separate email address on my work computer. Still, I don't think there is much to worry about. 23andme only looks at about one million SNPs.
 
2013-10-09 10:51:42 AM  

Quantum Apostrophe: "How about how likely you are to get Alzheimers or how fast your body processes caffeine? All of these clues are in your genes"

Or I could just drink a coffee and use a watch? I could just look up my family tree? What problem is this thing solving?


What if you're adopted?
 
2013-10-09 10:58:52 AM  

Ambivalence: Quantum Apostrophe: "How about how likely you are to get Alzheimers or how fast your body processes caffeine? All of these clues are in your genes"

Or I could just drink a coffee and use a watch? I could just look up my family tree? What problem is this thing solving?

What if you're adopted?


Mom? Dad? Can I just get you to open your mouths so I can get a swab and test to see if I'm adopted?
 
2013-10-09 11:55:10 AM  
I have nothing to worry about...


cache.ohinternet.com
 
2013-10-09 12:31:51 PM  

Quantum Apostrophe: "How about how likely you are to get Alzheimers or how fast your body processes caffeine? All of these clues are in your genes"

Or I could just drink a coffee and use a watch? I could just look up my family tree? What problem is this thing solving?


A family history tells you in broad strokes your likelihood for certain medical conditions on average, but that is done without knowing if you have actually inherited the genetic risk factors that are moving through your family tree. Knowing the exact factors and whether you have them can  potentiallygive you a much more exact estimate.

For genetic variants with a clear interpretation (many heritable cancers for instance) this can be a dramatic difference to know whether you do or don't carry the risk factor. Looking at a family tree doesn't tell you that, just the general probability that you inherited it.

Other traits are too complicated and may not have an output you can readily measure yourself. That said you have to be aware of the limitations of testing like 23andMe offers. Some of what it reports are very solid, others will have really broad risk percentages associated with them and are less actionable in terms of actual health.

Also, family trees are often incorrect, especially as you go back a few generations. And not in straightforward ways. Lots of children raised as siblings, etc.
 
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