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(The Daily Beast)   Worried about incurable tuberculosis? Stand by for incurable everything   (thedailybeast.com) divider line 35
    More: Scary, incurable, antibiotic resistance, medicinal chemistry, tuberculosis, Megan McArdle  
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3309 clicks; posted to Geek » on 14 Mar 2013 at 1:42 PM (1 year ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2013-03-14 01:53:10 PM  
Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.
 
2013-03-14 02:01:22 PM  

Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.


Either that or we'll get nanobots that kill anything they're programmed to dislike for one supremacists ideal of "human perfection".

static.wcnews.com

/obscure?
 
2013-03-14 02:07:58 PM  

Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.


I had a dream awhile back about VeritasTM Syrup ; it was a cough syrup type thing that was made from nanobots and would diagnose your entire body. That was available over the counter, the ones that actually fixed you were tightly controlled by the Government (Which was a giant corporation) and everyone lived in massive (1/3rd of a continent sized) domes that looked like the Ark from Wall-E because of rampant storms on the Earth's surface. Very Blade Runner aesthetically. Dreams are weird.
 
2013-03-14 02:10:07 PM  

Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.


Either that or, y'know, develop existing phage treatments into something slightly more clinically practical using scaled-up versions of existing techniques and replace the existing antibiotic infrastructure, something which we've only not already done because clinical science is mostly currently the province of non-biology specialists who are only comfortable with macro-scale treatments and because antibiotics are so absurdly idiot-proof that they'll be more cost-effective than anything else until they're completely obsoleted.

There are existing alternatives that aren't that difficult, scientifically, the only reason we haven't developed them is really just that there's no reason to yet.  No reason to go all grey goo on the problem, micrometer-scale is fine for this one.

//By "developed" I mean spend the money for full-on clinical trials and legislation capable of addressing genetic techniques beyond the current yes/no/NIMBY luddite nonsense.  They're already developed and in use in most of the old Soviet states in the case of phage therapy.
 
2013-03-14 02:12:02 PM  

Jim_Callahan: Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.

Either that or, y'know, develop existing phage treatments into something slightly more clinically practical using scaled-up versions of existing techniques and replace the existing antibiotic infrastructure, something which we've only not already done because clinical science is mostly currently the province of non-biology specialists who are only comfortable with macro-scale treatments and because antibiotics are so absurdly idiot-proof that they'll be more cost-effective than anything else until they're completely obsoleted.

There are existing alternatives that aren't that difficult, scientifically, the only reason we haven't developed them is really just that there's no reason to yet.  No reason to go all grey goo on the problem, micrometer-scale is fine for this one.

//By "developed" I mean spend the money for full-on clinical trials and legislation capable of addressing genetic techniques beyond the current yes/no/NIMBY luddite nonsense.  They're already developed and in use in most of the old Soviet states in the case of phage therapy.


Your solution doesn't involve tiny robots, therefore, I'm going to plug my ears and sing a song about tiny robots.

/la la la la la la la la
//tiiiiiiiiiny robots
///in my blood
 
2013-03-14 02:15:45 PM  

Duke Phillips' Singing Bears: Your solution doesn't involve tiny robots, therefore, I'm going to plug my ears and sing a song about tiny robots.

/la la la la la la la la
//tiiiiiiiiiny robots
///in my blood


Technically, viruses, including phage viruses, aren't "alive" in the biological sense, and the specific structure would have to be tailored to each target strain, so you can think of them as just being tiny mechanical hunter-killer drones for diseases based on carbon instead of silicon and steel if you like.
 
2013-03-14 02:19:40 PM  
THANKS OBAMA!
 
2013-03-14 02:25:39 PM  

Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.


Oh great, you just announced technology advances, you're gonna summon QA to shiat all over this
 
2013-03-14 02:34:41 PM  

Duke Phillips' Singing Bears: Jim_Callahan: Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.

Either that or, y'know, develop existing phage treatments into something slightly more clinically practical using scaled-up versions of existing techniques and replace the existing antibiotic infrastructure, something which we've only not already done because clinical science is mostly currently the province of non-biology specialists who are only comfortable with macro-scale treatments and because antibiotics are so absurdly idiot-proof that they'll be more cost-effective than anything else until they're completely obsoleted.

There are existing alternatives that aren't that difficult, scientifically, the only reason we haven't developed them is really just that there's no reason to yet.  No reason to go all grey goo on the problem, micrometer-scale is fine for this one.

//By "developed" I mean spend the money for full-on clinical trials and legislation capable of addressing genetic techniques beyond the current yes/no/NIMBY luddite nonsense.  They're already developed and in use in most of the old Soviet states in the case of phage therapy.

Your solution doesn't involve tiny robots, therefore, I'm going to plug my ears and sing a song about tiny robots.

/la la la la la la la la
//tiiiiiiiiiny robots
///in my blood


I want my tiny nanobot overlords to sing like smurfs
 
2013-03-14 02:35:37 PM  
This just in - you're never going to beat nature's population control measures. And, likewise, we need them to prevent a "hunger games" situation
 
2013-03-14 02:47:53 PM  
drvee.files.wordpress.com
 
2013-03-14 02:50:30 PM  

Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.


SO you want Obama to get power over drones inside our bodies!? Where does this infringement of civil liberties end!!
 
2013-03-14 03:13:24 PM  
The world will be a much better place when we are gone ...
 
2013-03-14 03:19:27 PM  

Jim_Callahan: develop existing phage treatments


Phage treatment is a neat idea, but there are some serious hurdles to overcome:


"The high bacterial strain specificity of phage therapy may make it necessary for clinics to make different cocktails for treatment of the same infection or disease because the bacterial components of such diseases may differ from region to region or even person to person.

In addition, due to the specificity of individual phages, for a high chance of success, a mixture of phages is often applied. This means that 'banks' containing many different phages must be kept and regularly updated with new phages.

Further, bacteria can evolve different receptors either before or during treatment; this can prevent the phages from completely eradicating the bacteria.

The need for banks of phages makes regulatory testing for safety harder and more expensive. Such a process would make it difficult for large-scale production of phage therapy. Additionally, patent issues (specifically on living organisms) may complicate distribution for pharmaceutical companies wishing to have exclusive rights over their "invention", making it unlikely that a for-profit corporation will invest capital in the widespread application of this technology."
 
2013-03-14 03:23:39 PM  
HOMEOPATHY WILL SAVE US

/totally sarcastic
 
2013-03-14 04:30:00 PM  

Lady Indica: HOMEOPATHY WILL SAVE US

/totally sarcastic


I hear homeopathy gets more effective the less of it you use.
 
2013-03-14 04:30:29 PM  

DarkSoulNoHope: Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.

Either that or we'll get nanobots that kill anything they're programmed to dislike for one supremacists ideal of "human perfection".



/obscure?


Either that, or they'll screw up and turn everyone into creepy gas-masked creatures looking for their Mummy.
 
2013-03-14 04:37:13 PM  
Reduction in risk from infection from surgery has more to do with antiseptic preparation than antibiotics.
 
2013-03-14 05:04:16 PM  
Should help out with those high unemployment numbers by a nice reduction in available workforce.

Always look on the bright side of your life....
 
2013-03-14 05:28:41 PM  

Brainsick: I had a dream awhile back about VeritasTM Syrup ; it was a cough syrup type thing that was made from nanobots and would diagnose your entire body. That was available over the counter, the ones that actually fixed you were tightly controlled by the Government (Which was a giant corporation) and everyone lived in massive (1/3rd of a continent sized) domes that looked like the Ark from Wall-E because of rampant storms on the Earth's surface. Very Blade Runner aesthetically. Dreams are weird.


Im totally stealing that idea. Look for MY novel Veritas Syrup in bookstores near you.
 
2013-03-14 05:41:57 PM  
Bacteriophages are going to come in handy in the era of antibiotic resistant bugs.  You want to make some easy cash, go patent a few critical bacteriophage genes.
 
2013-03-14 06:50:54 PM  

Brainsick: I had a dream awhile back about VeritasTM Syrup ; it was a cough syrup type thing that was made from nanobots and would diagnose your entire body. That was available over the counter, the ones that actually fixed you were tightly controlled by the Government (Which was a giant corporation) and everyone lived in massive (1/3rd of a continent sized) domes that looked like the Ark from Wall-E because of rampant storms on the Earth's surface. Very Blade Runner aesthetically. Dreams are weird.


"He say you Brade Runnuh!"

media.bladezone.com
 
2013-03-14 07:24:00 PM  

Lady Indica: HOMEOPATHY WILL SAVE US

/totally sarcastic


Actually, Homeopathy probably will save us.

People are cowards and tards. Our immune systems are good 99% of the time. Doctors need to be able to let them work naturally. If they can issue placebos, that would help slow or reverse the resitance trend.
 
2013-03-14 07:28:57 PM  
Interesting.  A direct correlation between bacterias' resistance to drugs, and the people's resistance to FartBongo taking our guns.

Maybe more guns IS the answer.
 
2013-03-14 07:42:28 PM  

DarkSoulNoHope: Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.

Either that or we'll get nanobots that kill anything they're programmed to dislike for one supremacists ideal of "human perfection".



/obscure?


Do you qualify the GenSelect bioweapon as an effective tool?
 
2013-03-14 08:18:47 PM  

doglover: Lady Indica: HOMEOPATHY WILL SAVE US

/totally sarcastic

Actually, Homeopathy probably will save us.

People are cowards and tards. Our immune systems are good 99% of the time. Doctors need to be able to let them work naturally. If they can issue placebos, that would help slow or reverse the resitance trend.


That's really only part of the problem. The other part are people with real illnesses that do need antibiotics ... and they don't finish their goddamned prescription.
 
2013-03-14 08:32:03 PM  

doglover: People are cowards and tards. Our immune systems are good 99% of the time. Doctors need to be able to let them work naturally. If they can issue placebos, that would help slow or reverse the resitance trend.


Next to sanitation/clean water and vaccination, antibiotics have saved more people than any other invention. Which is why heart disease and cancer are so prominent on the public health radar - transmissible diseases are well-controlled specifically due to concerted biomedical research.

Also, the advent of factory farming with prophylactic antibiotics has driven bacterial resistance far more than overuse by humans (which is a genuine problem but you substantially overstated its significance).
 
2013-03-14 10:06:24 PM  

drwiki: DarkSoulNoHope: Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.

Either that or we'll get nanobots that kill anything they're programmed to dislike for one supremacists ideal of "human perfection".

/obscure?

Do you qualify the GenSelect bioweapon as an effective tool?


If we can continue to perfect our methods of killing, then...

/glad people do remember Wing Commander :)
 
2013-03-14 10:17:27 PM  
Oh great, 'scientists' again. Why hasn't anyone taught me the controversy?
 
2013-03-14 10:28:12 PM  
Subby;
I would have gone with "Hey Farkettes, any of you have a headache right now?"
 
2013-03-14 10:28:47 PM  
shiat, wrong thread.
 
2013-03-15 12:22:48 AM  

Satanic_Hamster: Subby;
I would have gone with "Hey Farkettes, any of you have a headache right now?"


Satanic_Hamster: shiat, wrong thread.


Still works for the thread. :)
 
2013-03-15 02:04:42 AM  

DarkSoulNoHope: drwiki: DarkSoulNoHope: Duke Phillips' Singing Bears: Nanobots that hunt down pathogens with specific genetic codes. We'll get there. Someday, we'll kill everything we don't like. We're humans. It's what we do.

Either that or we'll get nanobots that kill anything they're programmed to dislike for one supremacists ideal of "human perfection".

/obscure?

Do you qualify the GenSelect bioweapon as an effective tool?

If we can continue to perfect our methods of killing, then...

/glad people do remember Wing Commander :)


I ran over the 4th disc ("So much action, it's on SIX CDs!" ) with a computer chair a few years back and don't have a computer old enough to run it anymore or it'd get another playthrough.
 
2013-03-15 02:42:54 AM  
I can only suggest DosBox, hopefully that could run Wing Commander well.
 
2013-03-15 09:01:20 AM  
Let the culling begin.

Ok with me if I'm included.
 
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