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(Medical Xpress)   Genetically engineered virus kills cancer. I think I've seen this movie before   (medicalxpress.com) divider line 19
    More: Spiffy, liver cancer, nature medicine, cancer types, smallpox, incurable, virus, virus kills  
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8434 clicks; posted to Geek » on 11 Feb 2013 at 12:45 AM (1 year ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2013-02-11 01:06:44 AM  
3 votes:

J. Frank Parnell: Actually, reading it again, it seems they might have just given one dose to the subjects, saw that it was very effective, then never gave them any more, and watched them die.

If continued usage of it is required, it's still just a treatment they'll milk people for, instead of a one time deal.


Well, since thousands of your cells turn rogue every day, I see this as a fair continued usage. I mean, why do those assholes make people take heart medications every day when it's clear you can just take one pill and be cured of hypertension? Clearly a scheme by Big Pharma.

In short, shut up.
2013-02-11 10:50:47 AM  
2 votes:

BenJammin: Still,  no cure for stupidity.


This! Until my stupidty is cured I don't care about anything else!
2013-02-11 09:51:31 AM  
2 votes:

3rotor: I'm just a bit confused by how they managed to get a 14 month survival rate, from a  trail period of only 4 weeks. Other than that , sound's good to me. Sign me up, Scotty!


That'd mean they were on the drug for 4 weeks. That's the 'trial period'. The 14 months would include that 4 weeks plus followup, which usually last until death or two or three years, whichever happens first. 

J. Frank Parnell: Fano: But saying that you don't need anything else in the fight against cancer is folly

What you definitely don't need is radiation and chemo, that much is certain. Radiation causes cancer, and studies are now showing chemo makes many cancers stronger. Even if those 'cures' manage to destroy the tumors they also damage everything else, like your immune system, and leave you with an extremely high chance to get cancer again because they are themselves highly carcinogenic.

What i was trying to get at earlier is mainly just that drug companies have no interest in cures because they don't make as much money as treatments, and that's what this sounds a bit like. Any potential cures they find are buried under years of tests while other dubious drugs are rushed to market and later found to be very dangerous.

/actually, just forget all that
//dioxins and radiation for you


Neither radiation or chemo work every time. They can, and occasionally do, make it worse. But they continue to be used because, on average, they do good. There's a reason that cancer mortality rates have been falling even though incidence is rising (http://globocan.iarc.fr/factsheet.asp), and it's improvements in surgery, drugs and radiation. Will all the lifestyle stuff you suggested to boost your immune system do some good? Yeah. It might decrease your chances of getting cancer, and it might help manage it once you've got it.
At any rate, this article isn't about chemo. A bit part of the reason oncolytic viruses are such a hot area (there are several others, some a lot closer to the market than this) is that they can provide the benefits of chemo without debilitating side effects.
Finally, if you don't think the pharma industry has an interest in cures, you haven't thought it through. In the long run, would it be more profitable to keep coming up with new treatments and not cure the disease? Only if one company had a monopoly. As it is, there are many drug companies, from Pfizer down to start-ups out of university labs. They're facing a huge patent cliff, where most of their best drugs will come off patent in the next couple years. When that happens, generics get in and prices promptly drop to around the cost of production. They need blockbuster drugs to fill those holes. Add in the fact that drug patents are globally standardized at 20 years now (with short extensions sometimes, but not much). It takes years to get a drug to market, and you generally have to patent early in the process. Once a drug hits the market, they control it for 10 years, 15 if they're really lucky. So you're in a cutthroat industry, facing a revenue problem. Your scientists come up with a potential cure. What do you do? Sit on it and try to come up with more treatment type drugs? Ok, then you run the risk that a competitor discovers the same thing and releases it, crushing your market. Even if they don't, you have to rely on your development pipeline to come up with an alternative that's provably better than what's currently on the market, and that's better than what your competitors come up with. Or you develop the cure, sell it, make unholy amounts of money and get hailed as a hero (the top cancer drug today, Avastin, is worth ~5 billion a year, and a cure for even one type of cancer would make more), and kick the fiscal can 15 years down the road. Which seems more like typical corporate behavior? The risky, hard work based long game approach, or get rich, get promoted, and leave the mess for the next guys?
You might argue that the drug companies have some sort of agreement to keep the ultra-competitive scenario I described above from happening. But even if you believe that it's possible for the dozen or so major drug companies around the world to enforce such a pact, there are always startups, usually formed by scientists who discover a single potential drug, looking to break in.
So even if you don't buy that the people who work at drug companies are people too and want to help patients, as Fano pointed out, the pure economics mean companies would have to be insane to sit on a cure for cancer. The reason they don't have one is that it's incredibly hard to find one. Mostly what they get are ones like this, that just hope to buy the patient some time, and hopefully improve their comfort. By the time you're trying out advanced therapies like this, you're usually terminal anyways.
2013-02-11 02:20:47 AM  
2 votes:

J. Frank Parnell: Fano: But saying that you don't need anything else in the fight against cancer is folly

What you definitely don't need is radiation and chemo, that much is certain. Radiation causes cancer, and studies are now showing chemo makes many cancers stronger. Even if those 'cures' manage to destroy the tumors they also damage everything else, like your immune system, and leave you with an extremely high chance to get cancer again because they are themselves highly carcinogenic.

What i was trying to get at earlier is mainly just that drug companies have no interest in cures because they don't make as much money as treatments, and that's what this sounds a bit like. Any potential cures they find are buried under years of tests while other dubious drugs are rushed to market and later found to be very dangerous.

/actually, just forget all that
//dioxins and radiation for you


Yeah, screw the win against polio, everyone was against that.

Keep in mind researchers and even the business guys suffer from cancer. Their loved ones do too. Are you saying that all of them are in on this conspiracy? Cancer is a difficult problem caused by normal biological processes. The idea we COULD cure cancer but don't is retard talk. What was Steve Jobs paid to keep up the act?
2013-02-11 01:59:27 AM  
2 votes:
My name is... well, it's not important.  I am a survivor living on the net. I am posting on all Fark threads. I will be at the 8.8.8.8 Google DNS server everyday at mid-day, when the bandwidth is best. If you are out there... if anyone is out there... I can provide caturday pics, I can provide rackspace, I can provide firewalls. If there's anybody out there... anybody... please. You are not alone.
2013-02-11 01:33:29 AM  
2 votes:
About a tenth of a percent of the population had the exact opposite effect...they've gone beyond madness...they killed everyone else...and not just killed...they've done things...
2013-02-11 01:14:25 AM  
2 votes:
It's not a movie, it's a novella.
www.orbitshortfiction.com
2013-02-11 11:38:11 AM  
1 votes:

Fark Rye For Many Whores: Still no cure for virus


spectaclesport.files.wordpress.com
2013-02-11 10:07:50 AM  
1 votes:

LincolnLogolas: HotWingAgenda: I was puzzled by the reference to it as a vaccine.  It's clearly not a preventative shot, more like a treatment for an existing cancer.

It's because the virus they used: They mutated the Vaccinia virus (thus named because it was used to vaccinate against Smallpox).


Actually, TFA states that the altered Vaccinia prompts the body's immune system into attacking the tumors. That makes it a vaccine.
2013-02-11 01:55:42 AM  
1 votes:

Yogimus: Fano: J. Frank Parnell: Fano: Well, since thousands of your cells turn rogue every day

Yeah, i was preaching that years ago here. There's cancer cells in all our bodies right now, and all that. Probably where you got it.

The other half of that knowledge, which you seem to have forgotten, is if your immune system is working fine, it can handle irregular cells with ease, and does so frequently. No need for medicine at all. It only becomes a problem when your immune system is suppressed or weakened significantly so it can't defend against them, and the cells begin to build up into tumors.

Some people would say the immune system is still capable of killing tumors on its own with proper lifestyle changes, but you, you should definitely get radiation and chemo. I insist on it.

Wow, you just doubled down on retard. Why have oncologists when you can just eat right and get exercise. Why, what else do you need? Are you selling some nutritional supplements? Because I would buy them from you if you had access to some good ones.

Why eat right and exercise, if you're just gonna get cancer, anyway?


I will post the caveat, "someday". Of course eating well and exercising are good for you, and rewarding as well. But saying that you don't need anything else in the fight against cancer is folly. I just mean they aren't enough, and I couldn't tell a cancer victim it's because they didn't eat perfectly and have just the right workout program. And also fark medicine for having a treatment that isn't one pill that protects you forever against abnormal cell division.
2013-02-11 01:40:47 AM  
1 votes:
i1184.photobucket.com
2013-02-11 01:32:29 AM  
1 votes:

J. Frank Parnell: Fano: Well, since thousands of your cells turn rogue every day

Yeah, i was preaching that years ago here. There's cancer cells in all our bodies right now, and all that. Probably where you got it.

The other half of that knowledge, which you seem to have forgotten, is if your immune system is working fine, it can handle irregular cells with ease, and does so frequently. No need for medicine at all. It only becomes a problem when your immune system is suppressed or weakened significantly so it can't defend against them, and the cells begin to build up into tumors.

Some people would say the immune system is still capable of killing tumors on its own with proper lifestyle changes, but you, you should definitely get radiation and chemo. I insist on it.


Wow, you just doubled down on retard. Why have oncologists when you can just eat right and get exercise. Why, what else do you need? Are you selling some nutritional supplements? Because I would buy them from you if you had access to some good ones.
2013-02-11 01:10:17 AM  
1 votes:
Also, what do you mean by "cancer"?
2013-02-11 01:06:51 AM  
1 votes:
I was puzzled by the reference to it as a vaccine.  It's clearly not a preventative shot, more like a treatment for an existing cancer.
2013-02-11 12:56:14 AM  
1 votes:
Actually, reading it again, it seems they might have just given one dose to the subjects, saw that it was very effective, then never gave them any more, and watched them die.

If continued usage of it is required, it's still just a treatment they'll milk people for, instead of a one time deal.
2013-02-11 12:52:33 AM  
1 votes:

RabidJade: As long as you use a lot of ice and a serum from an immune host you should be good.

//if not just drive to the safe haven in Connecticut or something


Or, ya know, allow the human race to evolve, like it did in the original ending.
2013-02-11 12:50:16 AM  
1 votes:
As long as you use a lot of ice and a serum from an immune host you should be good.

//if not just drive to the safe haven in Connecticut or something
2013-02-11 12:49:38 AM  
1 votes:
I'm sure everything--hang on, someone's banging on my do
2013-02-11 12:26:47 AM  
1 votes:
Still no cure for virus
 
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