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(Live Science)   I don't mean to worry anyone, but a top health official in Britain has called antibiotic-resistant bacteria a doomsday scenario just waiting to happen. Have a nice day   (livescience.com) divider line 51
    More: Scary, doomsday scenarios, Staphylococcus aureus, Britain, health officials, parliamentary immunity, bacteria  
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1738 clicks; posted to Geek » on 26 Jan 2013 at 4:40 PM (1 year ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2013-01-26 03:19:17 PM
Ah yes, this thread again. I'll just say this: People who can't even grab a door handle without a dainty ass-tissue are hilarious.
 
2013-01-26 04:33:06 PM
Well hell, Captain, relax and take some Trips.....
 
2013-01-26 04:41:18 PM
Yup.
 
2013-01-26 04:44:21 PM
I'm more worried about some lab- created thing being released on purpose than I am about the naturally occurring stuff.
 
2013-01-26 04:48:37 PM
Good. There are 6 billion too many farking people.
 
2013-01-26 04:51:11 PM
Nonsense. Most advancements in fighting infectious disease have come from public sanitation efforts and not some doctors or hospitals. You live longer now? Thank the garbage man and the people that clean your water. Not getting sick in the first place and all that.
 
2013-01-26 04:58:08 PM
Hah! Y'all called me crazy for buying a bunker, AK-47, and 500 cans of baked beans for the Mayan apocalypse but who's laughing now!
 
2013-01-26 04:58:50 PM
It was a race between the evolution of the microbes, and the evolution-denial of the fundies.

/ Darwin FTW ... aw, crap.
 
2013-01-26 04:59:32 PM

Richard C Stanford: Hah! Y'all called me crazy for buying a bunker, AK-47, and 500 cans of baked beans for the Mayan apocalypse but who's laughing now!


THE BEANS HAVE THE BACTERIA THE BEANS HAVE THE BACTER---
 
2013-01-26 05:01:05 PM

SpdrJay: I'm more worried about some lab- created thing being released on purpose than I am about the naturally occurring stuff.


The naturally-occurring stuff has a pretty good track record. The rising number of cases of resistant TB and the increasing prevalence of MRSA scare me plenty enough. Someone can correct me if I'm wrong, but wasn't the worst epidemic of the last century the 1918 flu? The flu. Killed millions, specifically striking the young and healthy with the greatest virulence.
 
2013-01-26 05:05:02 PM

born_yesterday: The naturally-occurring stuff has a pretty good track record. The rising number of cases of resistant TB and the increasing prevalence of MRSA scare me plenty enough. Someone can correct me if I'm wrong, but wasn't the worst epidemic of the last century the 1918 flu? The flu. Killed millions, specifically striking the young and healthy with the greatest virulence


At least the useful people are safe.
 
2013-01-26 05:09:07 PM
So basically, we'll just be back in the late 19th century all over again?
Women having to conceive 10 children starting at the age of 15 because
half are going to die to resistant bacteria X or Y?
 
2013-01-26 05:09:11 PM
I was going to make a "What an anti-biotic resistant doomsday scenario might look like?" quip, but there are just too many spoiled actress pictures to choose from.
 
2013-01-26 05:20:08 PM

born_yesterday: SpdrJay: I'm more worried about some lab- created thing being released on purpose than I am about the naturally occurring stuff.

The naturally-occurring stuff has a pretty good track record. The rising number of cases of resistant TB and the increasing prevalence of MRSA scare me plenty enough. Someone can correct me if I'm wrong, but wasn't the worst epidemic of the last century the 1918 flu? The flu. Killed millions, specifically striking the young and healthy with the greatest virulence.


Not to mention the totally-drug-resistant Gonorrhea. And that Clostridium Dificile that requires killing ALL your gut bacteria and then transplanting someone else's poop into your system.
 
2013-01-26 06:19:57 PM
www.celsias.com

Thanks Monsanto! by the way, how's that "feeding the world" thing going?
 
2013-01-26 06:21:32 PM

dionysusaur: Not to mention the totally-drug-resistant Gonorrhea. And that Clostridium Dificile that requires killing ALL your gut bacteria and then transplanting someone else's poop into your system.


I had c diff and didn't have to go through that, thankfully.

Thing is, no matter what bacteria/virus there is, someone, somewhere will beat it and not be affected by it. Hell, there are people who are immune to HIV
 
2013-01-26 06:21:46 PM

dionysusaur: born_yesterday: SpdrJay: I'm more worried about some lab- created thing being released on purpose than I am about the naturally occurring stuff.

The naturally-occurring stuff has a pretty good track record. The rising number of cases of resistant TB and the increasing prevalence of MRSA scare me plenty enough. Someone can correct me if I'm wrong, but wasn't the worst epidemic of the last century the 1918 flu? The flu. Killed millions, specifically striking the young and healthy with the greatest virulence.

Not to mention the totally-drug-resistant Gonorrhea. And that Clostridium Dificile that requires killing ALL your gut bacteria and then transplanting someone else's poop into your system.


At some point, we're going to have to put antibiotics on strict regulatory control. Meaning that if you want them, the doctor sees to it that you take every single dose, as ordered, and has the police bring you to him if you don't show up on time.

Because that's where drug resistant bugs come from... Idiot takes half the drugs, kills 95% of them, feels better since their immune system can clean up the rest on its own, and the most drug-resistant .1% are the last handful that escape when they fail to take the other half of the drugs even though the doctor said "take all of them on schedule."
 
2013-01-26 06:22:14 PM

Ego edo infantia cattus: [www.celsias.com image 435x290]

Thanks Monsanto! by the way, how's that "feeding the world" thing going?


Source that GMO crops have anything to do with this? I am pretty sure it is due to the overprescribing of antibiotics moreso than that.
 
2013-01-26 06:23:58 PM

Ego edo infantia cattus: Thanks Monsanto! by the way, how's that "feeding the world" thing going?


???

This, um, doesn't really have much of anything to do with GMO crops.
 
2013-01-26 06:27:20 PM

Ego edo infantia cattus: [www.celsias.com image 435x290]

Thanks Monsanto! by the way, how's that "feeding the world" thing going?


Dear Hippy,

You realize that GMO foods have nothing what so ever to do with human diseases becoming immune to antibiotics, right? If you posted a picture of a cow being fed antibiotics every day of its life to keep it alive in the horrifying disease-ridden squalor of the industrial farm in which it lives we might agree.

Also, supply of food is just fine; you're welcome. Planet is still having issues with distribution but that's not our problem.

-- Monsanto
 
2013-01-26 06:42:13 PM

AcneVulgaris: Good. There are 6 billion too many farking people.


There's always someone in every thread who wants someone to die. Politics threads, religion threads, iPhone vs Android threads, there's usually someone saying someone needs to die, and usually he gets roundly heckled and rightly so. Then we have comments about overpopulation, where it is seemingly acceptable to wish for the deaths of 6 billion people, and no one cares? I'm sure someone can misattribute a quote to Stalin summing it up.
 
2013-01-26 06:46:41 PM

mrlewish: Nonsense. Most advancements in fighting infectious disease have come from public sanitation efforts and not some doctors or hospitals. You live longer now? Thank the garbage man and the people that clean your water. Not getting sick in the first place and all that.


Not possible. The esteemed Fark Nobel laureates and PhDs have assured me that we don't live longer than 3000 years ago.
 
2013-01-26 06:51:21 PM
I was worried about this when I first heard about it in the 90's.
 
2013-01-26 06:52:55 PM

Slaxl: Then we have comments about overpopulation, where it is seemingly acceptable to wish for the deaths of 6 billion people


Well, I am more for 7 billion, but thats just me.
 
2013-01-26 07:08:41 PM
The worst part is that the people spreading the flu panic and contributing to people buying anti-bacterial everything should freaking know better. They know that the public panic will help create antibiotic resistant bugs, but they fearmonger anyway. Now look where we're headed!
 
2013-01-26 07:16:34 PM
This is why I wash my hands with a mild solution of lye.
 
2013-01-26 08:08:58 PM
Sounds like something out of a Spellberg movie
 
2013-01-26 08:24:27 PM
This is not like those other times such dire warnings from top officials have come. This time it's the first time you've seen it.
 
2013-01-26 08:40:39 PM

Nickninja: The worst part is that the people spreading the flu panic and contributing to people buying anti-bacterial everything should freaking know better. They know that the public panic will help create antibiotic resistant bugs, but they fearmonger anyway. Now look where we're headed!


Well, some of the anti-bacterial stuff, like, say, the hand-lotions, aren't realy antiobiotic based, and more "NUKE THEM WITH ALCOHOL" based.
 
2013-01-26 09:03:55 PM

alienated: Slaxl: Then we have comments about overpopulation, where it is seemingly acceptable to wish for the deaths of 6 billion people

Well, I am more for 7 billion, but thats just me.


Really, there's more than twice the number idiots I can deal with already.

/remember, the star trek universe had a nice ww3
 
2013-01-26 09:04:15 PM

sirgrim: born_yesterday: The flu. Killed millions, specifically striking the young and healthy with the greatest virulence

At least the useful people are safe.


Oh snap!
 
2013-01-26 10:21:28 PM
We already have airborne strains of TB that are not treatable with any antibiotic.

Care to see what it feels like to have your lungs slowly eaten away by bacteria until you finally suffocate or bleed out?

Meanwhile, your constant coughing spreads the bacteria around for others.

But on the plus side, the corporate factory farms were able to make the animals they raised gain weight a bit faster through constant additions of antibiotics to their food.

Yay profit.
 
2013-01-26 11:58:38 PM
Also, don't look at this image in the sidebar for too long
img849.imageshack.us
Or your heart will quietly fail.

/you've been warned
 
2013-01-27 09:24:46 AM
Antibiotics + evolution = superbugs. Who'da thunkit.
 
2013-01-27 10:05:22 AM
Is humanity smarter than evolution?

Stay tuned true believers ...
 
2013-01-27 11:06:06 AM

Felgraf: Nickninja: The worst part is that the people spreading the flu panic and contributing to people buying anti-bacterial everything should freaking know better. They know that the public panic will help create antibiotic resistant bugs, but they fearmonger anyway. Now look where we're headed!

Well, some of the anti-bacterial stuff, like, say, the hand-lotions, aren't realy antiobiotic based, and more "NUKE THEM WITH ALCOHOL" based.


This. And bacteria cannot become alcohol resistant (it is like you becoming resistant to being set on fire), so that isn't part of the problem. Same with bleach.
 
2013-01-27 12:22:30 PM

alienated: Slaxl: Then we have comments about overpopulation, where it is seemingly acceptable to wish for the deaths of 6 billion people

Well, I am more for 7 billion, but thats just me.


3.bp.blogspot.com
 
2013-01-27 12:25:56 PM

machoprogrammer: Felgraf: Nickninja: The worst part is that the people spreading the flu panic and contributing to people buying anti-bacterial everything should freaking know better. They know that the public panic will help create antibiotic resistant bugs, but they fearmonger anyway. Now look where we're headed!

Well, some of the anti-bacterial stuff, like, say, the hand-lotions, aren't realy antiobiotic based, and more "NUKE THEM WITH ALCOHOL" based.

This. And bacteria cannot become alcohol resistant (it is like you becoming resistant to being set on fire), so that isn't part of the problem. Same with bleach.


whatculture.com

So, we're going to have a bunch of "human torch" bacteria to deal with in a few years.

Yeah, I can see that being a doomsday situation.
 
2013-01-27 12:56:05 PM
Just a note, though the comment on GMOs was badly out of place:

Currently, the most common GMOs create a very similar situation on an agricultural level. They are engineered to be resistant to glyphosate and glufosinate (herbicides), in order to make it possible to basically spray said herbicides much more freely. Naturally, this has led to resistant weeds. The other major modification is a gene so plants produce Bt toxins (which are toxic to insects but otherwise very safe, though there is a difference between spraying the outside of a plant and having the plant produce the chemicals itself). This, also, has naturally led to resistant pests. Notice one of these things is a way to sell a ton of herbicide, though the other is more benign in a sense. Neither of them, however, have anything to do with feeding the world or making food more nutritious.

So, perhaps some of that enthusiasm for GMOs should be tempered. Just sayin'.

In any case, overuse/misuse of chemicals against unwanted organisms is a good way to set yourself up for trouble. If used carefully, then these chemical agents are a great boon. If used carelessly, though, not so much.
 
2013-01-27 02:24:47 PM

machoprogrammer: Felgraf: Nickninja: The worst part is that the people spreading the flu panic and contributing to people buying anti-bacterial everything should freaking know better. They know that the public panic will help create antibiotic resistant bugs, but they fearmonger anyway. Now look where we're headed!

Well, some of the anti-bacterial stuff, like, say, the hand-lotions, aren't realy antiobiotic based, and more "NUKE THEM WITH ALCOHOL" based.

This. And bacteria cannot become alcohol resistant (it is like you becoming resistant to being set on fire), so that isn't part of the problem. Same with bleach.


But you could fail to become resistant by denying yourself exposure to everyday bacteria.
 
2013-01-27 05:32:39 PM

machoprogrammer: And bacteria cannot become alcohol resistant (it is like you becoming resistant to being set on fire)


Not being a bacteriologist ... why can't bacteria become resistant to alcohol? What makes alcohol like fire to them?"
Google tells me it "dissolves cell membranes." Fine, but if more than a single molecule is needed to do that, I don't see why bacteria shouldn't be able to evolve alcohol resistance.
 
2013-01-27 08:16:44 PM

Uncle Tractor: machoprogrammer: And bacteria cannot become alcohol resistant (it is like you becoming resistant to being set on fire)

Not being a bacteriologist ... why can't bacteria become resistant to alcohol? What makes alcohol like fire to them?"
Google tells me it "dissolves cell membranes." Fine, but if more than a single molecule is needed to do that, I don't see why bacteria shouldn't be able to evolve alcohol resistance.


It would still go right through the second wall. It basically dissolves the cell wall and dries them out.
 
2013-01-27 09:27:40 PM

machoprogrammer: Uncle Tractor: machoprogrammer: And bacteria cannot become alcohol resistant (it is like you becoming resistant to being set on fire)

Not being a bacteriologist ... why can't bacteria become resistant to alcohol? What makes alcohol like fire to them?"
Google tells me it "dissolves cell membranes." Fine, but if more than a single molecule is needed to do that, I don't see why bacteria shouldn't be able to evolve alcohol resistance.

It would still go right through the second wall. It basically dissolves the cell wall and dries them out.


Fun fact: it also does the same to our cells, in high enough concentration. Our skin is already dead and dried out so it's not too bad, but this is why we don't drink pure lab alcohol, boys and girls.
 
2013-01-27 09:34:46 PM

Uncle Tractor: Not being a bacteriologist ... why can't bacteria become resistant to alcohol? What makes alcohol like fire to them?"
Google tells me it "dissolves cell membranes." Fine, but if more than a single molecule is needed to do that, I don't see why bacteria shouldn't be able to evolve alcohol resistance.


I should also mention: Most drug resistance is due to the mutation of a single protein (or group of proteins) that are the drug targets, making the drug unable to bind to its function. Think of it as a lock and key; the bacterial target protein is a lock, and the antibiotic is the key. Changing a couple of pins in the lock means the key doesn't fit anymore.

In order to do the same thing for alcohol, bacteria would need to basically come up with a brand-new set of resistance factors, which is just not the way evolution works. That being said, there are actually some bacteria that are becoming slightly alcohol-resistant or detergent resistant, so it's not like it's impossible...
 
2013-01-27 10:24:59 PM
I'm in the hospital right now hooked up to a venkomycin and cefazolin IV solution and I am thusly getting a kick out of these replies.

But I am in the US.

Watching Top Gear

Topsy Turvey world
 
2013-01-27 11:22:57 PM

Chameleon: Uncle Tractor: Not being a bacteriologist ... why can't bacteria become resistant to alcohol? What makes alcohol like fire to them?"
Google tells me it "dissolves cell membranes." Fine, but if more than a single molecule is needed to do that, I don't see why bacteria shouldn't be able to evolve alcohol resistance.

I should also mention: Most drug resistance is due to the mutation of a single protein (or group of proteins) that are the drug targets, making the drug unable to bind to its function. Think of it as a lock and key; the bacterial target protein is a lock, and the antibiotic is the key. Changing a couple of pins in the lock means the key doesn't fit anymore.

In order to do the same thing for alcohol, bacteria would need to basically come up with a brand-new set of resistance factors, which is just not the way evolution works. That being said, there are actually some bacteria that are becoming slightly alcohol-resistant or detergent resistant, so it's not like it's impossible...


It sounds like Mycobacterium are already somewhat resistant to alcohol though, so it is kind of misleading.
 
2013-01-28 12:43:35 AM

machoprogrammer: It sounds like Mycobacterium are already somewhat resistant to alcohol though, so it is kind of misleading.


Yeah, the waxy coat is inherently resistant to an extent. Since Mycobacteria are the only genera with the coat it's not something I'd lose much sleep over--regular bacteria aren't capable of adapting the coat (it would take way too much genetic adaptation) Also, the only major outbreaks seem to have been in immunocompromised people. Still, the idea of alcohol/detergent-resistant Mtb is not exactly a pleasant thought.
 
2013-01-28 03:09:48 AM

machoprogrammer: It would still go right through the second wall. It basically dissolves the cell wall and dries them out.


...But how much alcohol does it take to do this? Just one single molecule? If it requires more than that, isn't that the beginning of alcohol resistance? If a bacteria can survive one or two alcohol molecules but is killed by three, then a mutation should be able to let it's descendants survive three.

Chameleon: Yeah, the waxy coat is inherently resistant to an extent. Since Mycobacteria are the only genera with the coat it's not something I'd lose much sleep over--regular bacteria aren't capable of adapting the coat (it would take way too much genetic adaptation) Also, the only major outbreaks seem to have been in immunocompromised people. Still, the idea of alcohol/detergent-resistant Mtb is not exactly a pleasant thought.


If one kind of bacteria can do it, so can others. IMO, of course. This isn't my field.

Maybe a bacteria could evolve a way to process alcohol into something that doesn't harm it?
 
2013-01-28 03:23:14 AM

Uncle Tractor: Maybe a bacteria could evolve a way to process alcohol into something that doesn't harm it?


It did. It evolved into multi-cellular life and developed beer.
 
2013-01-28 11:04:45 AM
I'm always amazed at how often the journalists who report on antibiotics have no clue as to what makes them so useful. It's not just that they can kill bacteria, it's that they can kill bacteria inside you. Sure, a high concentration of hydrogen-peroxide can kill even the toughest of super bugs, but you can't inject that into your blood!
 
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