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(Gizmodo)   Scientists are working on an alcoholism vaccine that will give you terrible hangovers. Shh... don't tell them PBR already does that   (gizmodo.com) divider line 31
    More: Strange, alcoholism, vaccines  
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2364 clicks; posted to Main » on 26 Jan 2013 at 5:23 AM (1 year ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2013-01-26 12:52:06 AM  
I know it's not a vaccine, but doesn't Antabuse basically do the same thing?

And if this vaccine works how long before people will want to give it to their kids?
 
2013-01-26 12:55:26 AM  

fusillade762: I know it's not a vaccine, but doesn't Antabuse basically do the same thing?

And if this vaccine works how long before people will want to give it to their kids?


That's exactly what Antabuse does, and it's been around for decades. It doesn't cure alcoholism though, cause no sane alcoholic will take it.
 
2013-01-26 12:57:59 AM  
Who's this product aimed at?
 
2013-01-26 01:26:43 AM  

fusillade762: And if this vaccine works how long before people will want to give it to their kids?


From a successfully preventing alcohol abuse standpoint, that's the best use of it - if their first and every subsequent experience is really unpleasant, one has to assume they're not going to be doing many keg stands. But yeah it raises many questions about the extent of parental rights and whether it's acceptable at all for non-adults considering the vast majority of people use alcohol reasonably responsibly and have fun doing so.

I sure as hell would have avoided it had my first experience been similar to the day following five "Catamaran Killers", five shots of white liquor each. That was the worst thing in the history of ever, and I've broken most of the bones in my body and torn a goodly portion of the ligaments and things over the years.
 
2013-01-26 01:31:58 AM  

Confabulat: fusillade762: I know it's not a vaccine, but doesn't Antabuse basically do the same thing?

And if this vaccine works how long before people will want to give it to their kids?

That's exactly what Antabuse does, and it's been around for decades. It doesn't cure alcoholism though, cause no sane alcoholic will take it.


Disulfram (Antabuse) lasts a few weeks.

Asenjo is using gene therapy and hoping to get efficacy for several months after the initial injection. This looks like the paper (PDF warning) that describes the original idea, although it's a couple of years old.
 
2013-01-26 05:32:55 AM  
The other day I was hung over, but I didn't feel especially terrible. I just woke up and had a slight headache. Then out of nowhere I got nauseated and had some dry heaves. I took a shower and sat down. I didn't have much of an appetite, so I just had a glass of water, and I immediately felt nauseated again and threw up the water I just drank. Lather, rinse, repeat a few times and by 9am I was back to normal.

I try to stick to whisky, but that previous night I was trying everything.
 
2013-01-26 05:33:45 AM  
Because horrible comedowns are what deter most drug addicts.
 
2013-01-26 05:56:59 AM  
I get horrible hangovers and it keeps me more sober than I otherwise might be, though my hangovers could be worse as a result of only binge drinking once a month. I'm sure I'd handle them better if I did that twice a week, but once a month is plenty.
 
2013-01-26 06:01:20 AM  

swahnhennessy: I get horrible hangovers and it keeps me more sober than I otherwise might be, though my hangovers could be worse as a result of only binge drinking once a month. I'm sure I'd handle them better if I did that twice a week, but once a month is plenty.


Hair of the dog, man.
 
2013-01-26 06:08:16 AM  

AverageAmericanGuy: The other day I was hung over, but I didn't feel especially terrible. I just woke up and had a slight headache. Then out of nowhere I got nauseated and had some dry heaves. I took a shower and sat down. I didn't have much of an appetite, so I just had a glass of water, and I immediately felt nauseated again and threw up the water I just drank. Lather, rinse, repeat a few times and by 9am I was back to normal.

I try to stick to whisky, but that previous night I was trying everything.


Isn't it weird how mixing liquors like that leads to such awful hangovers when if you had consumed the equivalent amount of a single thing you would have been fine? I've always found it odd, and really irritating, and a recipe for disaster at the clubs.

OTOH,, I actually have a fond memory of one particularly bad hangover day, after I took my best friend to her first club/rave type thingy. We saw Oakenfold at Rain in Vegas. I'd been trying to get her to come with me to see a DJ spin for almost 10 years, and since she was in Vegas for a rotation I made it happen. Well, we were both hungover as all hell the next day but it was a fun say, staying in together and watching movies and eating hangover food. As miserable as we felt, it's a fond memory I wouldn't have had had we not had so much to drink of different things.
 
2013-01-26 06:11:24 AM  

Uchiha_Cycliste: AverageAmericanGuy: The other day I was hung over, but I didn't feel especially terrible. I just woke up and had a slight headache. Then out of nowhere I got nauseated and had some dry heaves. I took a shower and sat down. I didn't have much of an appetite, so I just had a glass of water, and I immediately felt nauseated again and threw up the water I just drank. Lather, rinse, repeat a few times and by 9am I was back to normal.

I try to stick to whisky, but that previous night I was trying everything.

Isn't it weird how mixing liquors like that leads to such awful hangovers when if you had consumed the equivalent amount of a single thing you would have been fine? I've always found it odd, and really irritating, and a recipe for disaster at the clubs.

OTOH,, I actually have a fond memory of one particularly bad hangover day, after I took my best friend to her first club/rave type thingy. We saw Oakenfold at Rain in Vegas. I'd been trying to get her to come with me to see a DJ spin for almost 10 years, and since she was in Vegas for a rotation I made it happen. Well, we were both hungover as all hell the next day but it was a fun say, staying in together and watching movies and eating hangover food. As miserable as we felt, it's a fond memory I wouldn't have had had we not had so much to drink of different things.


Next year I'll be out there CES. Company-sponsored hangover? I guess, if they insist.
 
2013-01-26 06:19:02 AM  
They insist, they insist.
Be sure to have the drinks with a vendor so that it's company business and try to get a receipt that doesn't say it was booze... some laces don't reimburse alcohol =(
 
2013-01-26 06:26:03 AM  

fusillade762: I know it's not a vaccine, but doesn't Antabuse basically do the same thing?

And if this vaccine works how long before people will want to give it to their kids?


If today's parents could get away with it they would all vaccinate their kids against drinking, smoking, boob groping, asking questions, falling in love, and living in general.
 
2013-01-26 06:41:40 AM  
Let me get this straight... You expect addicts to decide not to abuse their chemical of choice based on consequences? If consequences were all it took, there would be no addicts.
 
2013-01-26 06:57:26 AM  

Honest Bender: Let me get this straight... You expect addicts to decide not to abuse their chemical of choice based on consequences? If consequences were all it took, there would be no addicts.


*ding* *ding* *ding*
 
2013-01-26 07:35:19 AM  
Are the ingredients ipecac, mustard, cayenne, asafetida, and gunpowder?

Is this the "scientist" in question?
www.imfdb.org
 
2013-01-26 07:50:54 AM  

Smgth: Addicts are hardly going to stop because what they're doing is all of a sudden even more unpleasant then usual...if the effects of what they were doing were enough to put them off, almost no one would be addicted to ANYTHING! Isn't the definition of an addict 'someone who repeatedly does something DESPITE the myriad adverse effects'?


no

Adverse side effects happen when an addict STOPS taking their addictive drug of choice.
Intended effects occur when they ingest their addictive drug of choice.
 
2013-01-26 07:54:07 AM  

Honest Bender: Let me get this straight... You expect addicts to decide not to abuse their chemical of choice based on consequences? If consequences were all it took, there would be no addicts.


And addicts straighten up every day because of the consequences of their addiction, too.
 
2013-01-26 08:06:00 AM  

Honest Bender: Let me get this straight... You expect addicts to decide not to abuse their chemical of choice based on consequences? If consequences were all it took, there would be no addicts.


A friend of mine has the mutation that this drug is trying to express. Even one shot of alcohol causes him to go straight into hangover mode, with no buzz to appreciate. So it's not just about increasing the consequences, it's about taking the enjoyment out of it as well.
 
2013-01-26 08:12:14 AM  
Any parent that gives this to their mud is a farking a-hole.

And lots of parents are just that.
 
2013-01-26 08:13:08 AM  
Because these types of negative reinforcement techniques work so well with alcoholics.
 
2013-01-26 08:42:06 AM  
What they should do is make a pill that triples your liver's toxin processing power against ethanol.

No one's gonna waste money on booze if they can't get glassy eyed anymore.
 
2013-01-26 08:45:41 AM  

HST's Dead Carcass: Because these types of negative reinforcement techniques work so well with alcoholics.


I took antabuse when I was trying to sober up. I had to sign a paper that if I drank while on it and died, tough shiat--the people who gave it to me were not responsible.

I drank on it, of course. My face turned bright red, my whole body got bright red blotches on it, my head started pounding, and then I went into a blackout after a couple of drinks. So yes, in that fashion--it worked. It took every bit of enjoyment out of drinking, I thought I might have a heart attack, and blackouts are scary enough without knowing that you're going to have one if you even touch alcohol.

I didn't take it for very long, but it did the trick. Whenever I thought about drinking after that, I kept telling myself that if I couldn't get my shiat together, I'd have to take the Antabuse again. And that usually worked.
 
2013-01-26 09:41:34 AM  
How soon before MADD demands that everyone under 21 be injected with this in order to cut down on underage drinking?
 
2013-01-26 09:58:58 AM  
Why do you need a vaccine? Feed your target with inky cap mushrooms (Coprinopsis atramentaria). The target won't be able to drink for days without facial reddening, nausea, vomiting, malaise, agitation, and palpitations possibly leading to heart attack.
 
2013-01-26 10:31:54 AM  
Unavailable for comment:

i45.tinypic.com
 
2013-01-26 12:23:52 PM  

arcas: How soon before MADD demands that everyone under 21 be injected with this in order to cut down on underage drinking?


Not just under 21. Everybody. Because if you have 1 beer at home you'll go out driving and run over a dozen babies
 
2013-01-26 01:16:40 PM  
It inoculates against TF?
 
2013-01-26 01:21:08 PM  
Michelob too, at least for me. I'll have a headache before I finish drinking half a bottle of that stuff.
 
2013-01-27 12:43:01 PM  
so it's basically Four Loko?
 
2013-01-27 09:03:07 PM  

edmo: Michelob too, at least for me. I'll have a headache before I finish drinking half a bottle of that stuff.


Busch beer also .
 
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