If you can read this, either the style sheet didn't load or you have an older browser that doesn't support style sheets. Try clearing your browser cache and refreshing the page.

(Boobies)   Scientists believe they're a large step closer to curing AIDS, despite massive clamoring from the scientific community to figure out more important issues like why we always stick USB drives in upside down   (firstpost.com) divider line 168
    More: Cool, aides, USB, drug therapies, scientific community, Queensland Institute of Medical Research, David Harrich, proteins  
•       •       •

9331 clicks; posted to Main » on 16 Jan 2013 at 11:09 AM (1 year ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



168 Comments   (+0 »)
   
View Voting Results: Smartest and Funniest

Archived thread

First | « | 1 | 2 | 3 | 4 | » | Last | Show all
 
2013-01-16 11:49:00 AM
I'm not an evolutionary biologist, but could this work? It seems to me that all you're doing is introducing a very poor competitor into a gene pool. The HIV that is replication-inhibited would fail to replicate, while the normal HIV would continue to run amok. This is like trying to drive human beings extinct by introducing a few hundred million sterile people into the world. Except even worse, because viruses reproduce asexually.
 
2013-01-16 11:49:48 AM
If you don't see any problem with the standard USB form factor then I sincerely hope you are not an engineer.
 
2013-01-16 11:50:20 AM

joseelsegundo: Yeah subby's totally right on about the USB drives. And don't get me started about those farking reversed concave spoons!


FTFM
 
2013-01-16 11:50:45 AM
One step closer, only 27,130,583 steps to go.
 
2013-01-16 11:51:54 AM
Done already...
Link (http://www.flipperusb.com)
and here:
Link (http://www.redferret.net/?p=25333)
 
2013-01-16 11:52:05 AM

orbister: The USB symbol goes on top.
[static.guim.co.uk image 400x194]


That only works if the port is horizontal. Since most of the machines I work with are tower workstations, it doesn't help me.
 
2013-01-16 11:53:31 AM
I always wondered why they didn't design USB so you could plug it in either way and it would just work. The only thing I can figure is that no one considered we would be using things like flash drives and cellphone chargers that are constantly being plugged in and unplugged.
 
2013-01-16 11:55:51 AM

aedude01: Kazan: there already IS a cure. it just isn't a feasible one. bone marrow translates from elite controllers (people with natural genetic immunity)

Correct me if I'm wrong, but didn't they recently discover that it's any bone marrow transplant that works, not just one from elite controllers?


no. it must be from an elite controller, because you're gaining the elite controllers immunity. transplant from a normal person just gives aids more cells it can infect.
 
2013-01-16 11:56:40 AM

vudukungfu: Stop sticking USB drives in the wrong hole.


That's how you get ComputerAIDS.
 
2013-01-16 11:58:54 AM

orbister: The USB symbol goes on top.
[static.guim.co.uk image 400x194]


Most of the time. I have 2 cables and chargers from 2 different vendors that go in opposite ways.

The people that designed USB completely failed Poka-Yoke design.
 
2013-01-16 11:59:11 AM
Unlike AIDS - the USB connector is badly designed.

/window seat
 
2013-01-16 11:59:47 AM
Right... a "cure". It'll only take years of very expensive medicines that the quack will use to "treat" your AIDS.

/thank FSM we have boner pills
 
2013-01-16 12:00:02 PM

movieman_1979: "...like why we always stick USB drives in upside down"

Shiat ain't funny. I do that all the farking time!


For something that has the word Universal right in the farking name, this is irritating.
 
2013-01-16 12:00:42 PM
*puts on tinfoil hat*

Magic Johnson doesn't have AIDS and never had AIDS but they needed a recognizable and likable spokesperson to get the message out and help garner compassion in the 90s and a straight guy named Magic Johnson was too perfect to pass us up.

*takes of tinfoil hat*

*shrugs*
 
2013-01-16 12:01:07 PM
One unqualified good thing about "lightning": no "top" or "bottom".
fark knows why they couldn't figure that out before they released Light Peak/Thunderbolt.

Yes, it was an improvement over 70s/80s design to have keyed plugs so that you couldn't put the cord in 'wrong' and fry your gadget.
But this is the year 2013 ffs. Auto-sensing how the thing is plugged in and handling shiat properly without frying things is well understood.

Catch the fark up, propeller-heads.

/ USB is a lost cause
// or would be, in a sane world
 
2013-01-16 12:01:17 PM

Digital Communist: If you don't see any problem with the standard USB form factor then I sincerely hope you are not an engineer.


There's an easy fix, just paint half the plug and half the jack. Then you can see which way it goes.
 
2013-01-16 12:02:04 PM
one drug, one protein... let's get together and feel all right
 
2013-01-16 12:04:29 PM

Ghastly: Once they cure AIDS the super herpes virus will kill us all.


My 15 year old brother in-law was playing a game where you create a disease to wipe out the world (yes, I know). He named it Flurpes. Now, we are all terrified of getting the Flurp.
 
2013-01-16 12:04:36 PM

ElBarto79: I always wondered why they didn't design USB so you could plug it in either way and it would just work. The only thing I can figure is that no one considered we would be using things like flash drives and cellphone chargers that are constantly being plugged in and unplugged.


Because certain pins were for current and others were for data. If you made it reversible then both the device and the host would have to have some intermediate logic added (read: cost) to determine what each pin is for based on how it's plugged in.
 
2013-01-16 12:08:01 PM

busy chillin': *puts on tinfoil hat*

Magic Johnson doesn't have AIDS and never had AIDS but they needed a recognizable and likable spokesperson to get the message out and help garner compassion in the 90s and a straight guy named Magic Johnson was too perfect to pass us up.

*takes of tinfoil hat*

*shrugs*


He never did have AIDS... he only has The HIV
 
2013-01-16 12:08:31 PM

roc6783: Ghastly: Once they cure AIDS the super herpes virus will kill us all.

My 15 year old brother in-law was playing a game where you create a disease to wipe out the world (yes, I know). He named it Flurpes. Now, we are all terrified of getting the Flurp.


So move to Madagascar.
 
2013-01-16 12:09:04 PM

Donnchadha: busy chillin': *puts on tinfoil hat*

Magic Johnson doesn't have AIDS and never had AIDS but they needed a recognizable and likable spokesperson to get the message out and help garner compassion in the 90s and a straight guy named Magic Johnson was too perfect to pass us up.

*takes of tinfoil hat*

*shrugs*

He never did have AIDS... he only has The HIV


okie dokie...he doesn't have HIV either.
 
2013-01-16 12:09:21 PM

roc6783: Ghastly: Once they cure AIDS the super herpes virus will kill us all.

My 15 year old brother in-law was playing a game where you create a disease to wipe out the world (yes, I know). He named it Flurpes. Now, we are all terrified of getting the Flurp.


Fortunately, we've got a supply of flurbiprofen to help combat it
 
2013-01-16 12:10:42 PM

busy chillin': *puts on tinfoil hat*

Magic Johnson doesn't have AIDS and never had AIDS but they needed a recognizable and likable spokesperson to get the message out and help garner compassion in the 90s and a straight guy named Magic Johnson was too perfect to pass us up.

*takes of tinfoil hat*

*shrugs*


Perry Farrell had the aids too.
Remember when Magic had his talk show 'the magic hour'?  He had Howard Stern on one time, and it was hilarious.  HS is telling Magic he had fun getting aids.  Now Howard, no one has fun getting aids.  Ah ah buddy, you had fuuuuuuun getting aids.
 
2013-01-16 12:11:41 PM

orbister: The USB symbol goes on top.
[static.guim.co.uk image 400x194]


Not always, but when it doesn't, the cable manufacturer puts their logo there. Seems to work every time for me.
You know they could engineer USB 4.0 to be like that Apple socket on the new iPhone. Then all this goes away. It would even be backwards compliant since you could slide it in like this MicroSD adapter. All it needs are pins on the other side.
 
2013-01-16 12:12:18 PM
USB replaced both RS 232, principally, and SCSI. Both of those were impossible to install in small spaces that you couldn't see, and, if you were wrong, you might bend the pins. Some SCSI cable cost as much as $300.
 
2013-01-16 12:15:24 PM

offacue: NightOwl2255: offacue: NightOwl2255: /Always wear your jimmy.

I didn't pay a doctor to slit holes in my nuts and fish around inside to tug out the little strings to cut them and tie knots in them and stuff them back in and sew up the holes with a needle and thread so I could wear a "Jimmy" while I bang my wife of 19 years.

Yeah, but the guys that she's banging on the side, may not be wearing a jimmy either.

/Kidding!
//I'm sure they are wearing one.

Then it won't matter when I systematically torture and eventually kill them since I'm just gonna die from the aids anyhow. Right? Right?


Dude, maybe you should talk to your doctor about increasing your meds. And you might mention that stick in your ass while you're at it.
 
2013-01-16 12:17:45 PM
In all seriousness, the USB plug is a pretty piss-poor design.
 
2013-01-16 12:19:16 PM
The fork-shaped icon should always face upwards.

/At least with Apple products.
 
2013-01-16 12:19:58 PM

Jument: In all seriousness, the USB plug is a pretty piss-poor design.


Yeah, It was cooler when you wanted to plug in your zip drive and you had to shut your computer down and put those tiny screws of the SCSI cable in the plug in the back and then restart. Good times.
 
2013-01-16 12:20:33 PM
Next up, Queensland Institute of Medical Research researchers discover a new prion that causes brain tissue to melt...

/ hoping not.

On the USB question, I put a stripe of neon-green nail polish on the "away-from-the-motherboard" side of the USB sticks and cables that stay in my tech support kit. You can't miss it visually, and you can at least feel the bump when you're crawling around under a desk.
 
2013-01-16 12:21:35 PM

Sock Ruh Tease: This article from Boobies.com is very informative.


Came here to point this out, so instead I'll just note that the research was done at Quimmer.
 
2013-01-16 12:22:49 PM

maxheck: Next up, Queensland Institute of Medical Research researchers discover a new prion that causes brain tissue to melt...

/ hoping not.

On the USB question, I put a stripe of neon-green nail polish on the "away-from-the-motherboard" side of the USB sticks and cables that stay in my tech support kit. You can't miss it visually, and you can at least feel the bump when you're crawling around under a desk.


I can't see green so I'm still screwed! lol
 
2013-01-16 12:24:12 PM

wingding:

I can't see green so I'm still screwed! lol


derbyimages.woot.com
 
2013-01-16 12:25:34 PM
In case it hasn't already been posted: USB icon is on the side that goes up.
 
2013-01-16 12:25:58 PM
So how long until this research mysteriously falls off the face of the earth?
 
2013-01-16 12:26:23 PM
images.gizmag.com

commonsenseatheism.com
 
2013-01-16 12:28:29 PM
wingding:

maxheck: Next up, Queensland Institute of Medical Research researchers discover a new prion that causes brain tissue to melt...

/ hoping not.

On the USB question, I put a stripe of neon-green nail polish on the "away-from-the-motherboard" side of the USB sticks and cables that stay in my tech support kit. You can't miss it visually, and you can at least feel the bump when you're crawling around under a desk.

I can't see green so I'm still screwed! lol


Well, you can probably tell "not black" better than the black-bas relief-on-black plastic USB logo on most cables and devices.

/ uses hot pink nail polish for marking car parts for reassembly.
 
2013-01-16 12:28:40 PM

lennavan: roc6783: Ghastly: Once they cure AIDS the super herpes virus will kill us all.

My 15 year old brother in-law was playing a game where you create a disease to wipe out the world (yes, I know). He named it Flurpes. Now, we are all terrified of getting the Flurp.

So move to Madagascar.


Donnchadha: roc6783: Ghastly: Once they cure AIDS the super herpes virus will kill us all.

My 15 year old brother in-law was playing a game where you create a disease to wipe out the world (yes, I know). He named it Flurpes. Now, we are all terrified of getting the Flurp.

Fortunately, we've got a supply of flurbiprofen to help combat it


I love Fark.
 
2013-01-16 12:33:23 PM
They say it wouldn't be a cure for 'hiv infection', but i believe it would... If you are able to stop the virus from replicating, the immune system would take care of whatever remnants were already in the body.

Tommy Moo: I'm not an evolutionary biologist, but could this work? It seems to me that all you're doing is introducing a very poor competitor into a gene pool. The HIV that is replication-inhibited would fail to replicate, while the normal HIV would continue to run amok. This is like trying to drive human beings extinct by introducing a few hundred million sterile people into the world. Except even worse, because viruses reproduce asexually.


The modified virus will then attack the non-modified virus. As it stands, current medication can drive the virus down to nearly undetectable levels, however, its accumulates once again if medication is stopped.

So.. if a patient who is on effective medication is then introduced to the modified virus, it will already have a leg up on the game, as there won't be much competition left to fight. Who knows, maybe at that point, the immune system will be able to eradicate the rest of the virus all by itself.
 
2013-01-16 12:33:56 PM

JamesSirBensonMum: I've always believed in the quantum state of USB plugs.
[www.globalnerdy.com image 550x483]


I wonder how many people actually get that :)
 
2013-01-16 12:34:40 PM

JamesSirBensonMum: I've always believed in the quantum state of USB plugs.
[www.globalnerdy.com image 550x483]


Accurate.
www.maniacworld.com
 
2013-01-16 12:35:28 PM
I had a hell of a time plugging an HDMI cable into the back of my television last night.
I know, it's not even remotely relevant, but I wanted to participate.
 
2013-01-16 12:36:25 PM
While on the USB question: how come they also fit into an Ethernet port?
 
2013-01-16 12:36:49 PM

dk47: In case it hasn't already been posted: USB icon is on the side that goes up.


Now, if only all USB plugs followed that standard.

And if only all USB ports were not 90° perpendicular to the "up-down" axis.

And if only all USB drives had that icon at all.

:-\
 
2013-01-16 12:37:08 PM

zarberg: The Angry Hand of God: The last thing in the world you would want is to find your Jimmy being sold next to a broken toaster being sold for $22, and have to talk the guy down to $17. Just make sure you take it home and wash it off, then you should feel complete again.

I saw them in concert once, their guitarist looked like Sam Kinison added 200 lbs, and some completely stoned girl spent half the concert with her hand in my pants.

/CSB


Did you finish?
 
2013-01-16 12:37:41 PM

zarberg: The Angry Hand of God: The last thing in the world you would want is to find your Jimmy being sold next to a broken toaster being sold for $22, and have to talk the guy down to $17. Just make sure you take it home and wash it off, then you should feel complete again.

I saw them in concert once, their guitarist looked like Sam Kinison added 200 lbs, and some completely stoned girl spent half the concert with her hand in my pants.

/CSB


had backstage passes to see them at the 9:30 club in Wash DC back in the 90's sometime..

As I was waiting for the band to come in, two girls with broken noses came in bleeding everywhere. The slammed danced into each other.

The band came in and offered them a ride home in their limo.
 
2013-01-16 12:38:57 PM
T.rex:

They say it wouldn't be a cure for 'hiv infection', but i believe it would... If you are able to stop the virus from replicating, the immune system would take care of whatever remnants were already in the body.Tommy Moo: I'm not an evolutionary biologist, but could this work? It seems to me that all you're doing is introducing a very poor competitor into a gene pool. The HIV that is replication-inhibited would fail to replicate, while the normal HIV would continue to run amok. This is like trying to drive human beings extinct by introducing a few hundred million sterile people into the world. Except even worse, because viruses reproduce asexually.

The modified virus will then attack the non-modified virus. As it stands, current medication can drive the virus down to nearly undetectable levels, however, its accumulates once again if medication is stopped.

So.. if a patient who is on effective medication is then introduced to the modified virus, it will already have a leg up on the game, as there won't be much competition left to fight. Who knows, maybe at that point, the immune system will be able to eradicate the rest of the virus all by itself.


IANABiologist, but the way I read the article is that they're not modifying HIV, they're flooding the patient's system with this "almost-but-not-quite-HIV's" protien and that's interfereing with HIV's replication.
 
2013-01-16 12:39:09 PM

Jument: In all seriousness, the USB plug is a pretty piss-poor design.


The thing was designed in the mid 90s, perhaps earlier. Not bad considering.
 
2013-01-16 12:39:19 PM

Donnchadha: roc6783: Ghastly: Once they cure AIDS the super herpes virus will kill us all.

My 15 year old brother in-law was playing a game where you create a disease to wipe out the world (yes, I know). He named it Flurpes. Now, we are all terrified of getting the Flurp.

Fortunately, we've got a supply of flurbiprofen to help combat it


Phineas and Flurb
 
Displayed 50 of 168 comments

First | « | 1 | 2 | 3 | 4 | » | Last | Show all

View Voting Results: Smartest and Funniest


This thread is closed to new comments.

Continue Farking
Submit a Link »






Report