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(BBC)   Faster DNA sequencing controls MRSA outbreak at socialist hospital. "We think this is the first case where whole genome sequencing has actually led to a clinical intervention and brought the outbreak to a close"   (bbc.co.uk) divider line 8
    More: Cool, MRSA, genome sequencing, Wellcome Trust Sanger Institute, DNA sequencing, The Lancet Infectious Diseases, genetic code  
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1995 clicks; posted to Geek » on 14 Nov 2012 at 7:20 AM (1 year ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2012-11-14 08:28:16 AM
3 votes:
Medicine takes an amazing step so what do we discuss?

i224.photobucket.com
2012-11-14 09:48:56 AM
1 votes:
"We think this is the first case where whole genome sequencing has actually led to a clinical intervention and brought the outbreak to a close."

No.

NIH uses genome sequencing to help quell bacterial outbreak in Clinical Center
2012-11-14 09:31:59 AM
1 votes:

Xai: Hey, don't talk about prayer that way! Prayer always works in diligently sending all people afflicted with any ailment directly to Heaven.


I'm not sure how prayer go into the GEEK tab, but if we must discuss it ... I have a child who has/had an illness we have tracked since infancy. This child has a specialist, quarterly blood work, has had to undergo a biopsy. At times, depending on how the things with the illness were going, the blood work has been monthly or even weekly. This child had been placed on an experimental medication to control the illness, but it was a flop.

Our specialist knows that though I am merely an English major and not science savvy (please don't even ask about math); I have an interest in science. I like reading about science. I love reading on any topic that might benefit my children. The specialist encouraged me, helped me subscribe to a magazine meant for medical professionals, pointed me to websites, and so on.

My child got worse and the specialist was looking at controlling the illness only. So, I happened upon a medication approved for adults only that has a 10% cure rate. I read about it, went in, and requested the med for my child. The doctor said "No, because you're looking for a cure. That's not going to happen and you're going to get mad at me."

Well, that didn't dissuade me. We continued to talk. Finally, the doctor said "No one even really understands why the ten percent that are cured are cured. It's not approved. We're going to have to fight the insurance company. But you've sold me on trying it, but only if you will pray for and ask your meeting for worship (that probably was not the term he used) to pray for xxx." I agreed and he stated he would also put in a prayer request at his faith home. I did not know this mans' beliefs and would not have suggested prayer to him for fear of offending him. I just would have quietly done it without involving him. I went further and wrote each of my four siblings in four different cities and had them ask the people at their faith homes to pray for my child.

A woman at our meeting for worship who is a bit older than my mother, who lost a child to childhood cancer, and is very fond of my children; swung into action the best way she knew how. She emailed me diet tips for building the immune system with kid friendly recipes almost every week. She dug through alternative treatment literature and sent me articles on acupuncture among other things. And she carried a prayer request to the two other faith groups she attends: a Buddhist Temple and a local, liberal (her description) Mosque. Per this woman, someone at the Mosque passed that request onto all the other Mosques in the city.

So, people who attend at least one synagogue, five Christian groups, one Buddhist temple, and handful of Mosques prayed for my child. Here's the important part for those of you who think all Christians are anti-science: in addition to the prayers, I gave my child injections of medication. (You can't imagine how scary that task is until you have to do it.)

As far as we can tell at this time, my child has been blessed with the cure that her specialist, at one point, thought was impossible. S/he is due for lab work around Christmas. If it's all good, s/he'll have another follow-up a year from now. I think s/he'll have to be tracked most of his/her life. Still, we could not have hoped for a better outcome.

I do not believe G-d is judging either the children or the parents when an illness takes a child away as happened with my friend and her son. I do not believe G-d causes or inflicts illness on us. Nor do I believe G-d to be all-powerful with the capacity to override any and every bad thing that might ever happen to any of us. I suppose that's heresy to a certain extent.

I do believe that G-d is love. I believe that calling upon that love creates some subtle force or energy in our world. I believe that science glorifies G-d and that, if science threatens your notion of G-d, maybe your faith wasn't so great to begin with. I think both prayer and science are valuable and useful.

This statement came out longer than I had intended.
2012-11-14 09:17:22 AM
1 votes:

Lunaville: It would scare the hooey out of me if I were in any sort of supervisory position in a hospital that had 12 babies infected with MRSA. Great, innovative work demonstrated though. I do hope it spreads and benefits many others.


Maybe not the best choice of words there...
2012-11-14 08:49:42 AM
1 votes:
Its pretty amazing how far sequencing has come in less than 10 years. "Second-Generation" sequencing only became widely available in 2008. In four years it has improved by orders of magnitude and third-generation technologies are now available. We are rapidly approaching $1000 for a whole human genome to be resequenced (its about 5k-10k right now) and exomes (just the gene coding regions) is about 1-2k at the moment. And for bacterial outbreaks like this or the E.coli outbreak last year, and viral outbreaks, we now really can leverage sequencing to intervene in real time. Clinical use of human genomics has already started as well. At least one children's hospital is doing it for every infant who has to be admitted in to NICU to try and identify any genetic conditions.
2012-11-14 08:13:43 AM
1 votes:

BronyMedic: Bontesla: How many times has prayer been solely responsible for something similar?

Really? Do I have to be that guy?

[www.designsbybethann.com image 360x360]


I think he was comparing prayer to an insidious infection that sweeps through a closed population killing all that stand it its way.

Which sounds about right.
2012-11-14 08:12:30 AM
1 votes:
It's nice to see the good guys win once in a while.
2012-11-14 08:10:28 AM
1 votes:
But this can't be possible... they have national health care.. and thats bad.. nothing good could happen there...
 
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