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(Telegraph)   Cure for cancer found. Still no cure for ... oh wait   (telegraph.co.uk) divider line 35
    More: Cool, liver cancer, cancer types, cell lines, theses, Amgen, Uppsala, neuroendocrine cancer, rare disease  
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25060 clicks; posted to Main » on 01 Sep 2012 at 1:51 PM (2 years ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



Voting Results (Smartest)
View Voting Results: Smartest and Funniest


Archived thread
2012-09-01 02:02:00 PM
6 votes:
there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.
2012-09-01 02:08:39 PM
4 votes:
Another example of how the American government, forming its laws around and to support big business in certain areas, has made opportunities for other organizations doing the same thing any other way disappear. Like US auto makers made immune from threats from startup car companies, or any other business with a ridiculously high regulatory barrier for entry.

Everyone likes to believe the reason we haven't found a cure for cancer is that no one's discovered it. The truth is, no one knows a way to make it pay for its own development because the American health care business is fossilized into one very profitable business model that the government won't change for fear of losing its income stream.
2012-09-01 01:54:16 PM
4 votes:
This is the first and probably last time we'll ever hear about this.
2012-09-01 02:55:17 PM
3 votes:
I'll just leave this here....
Oncolytics Biotech - Reolysin

/Naturally occurring Reovirus (Not modified)
//Incredible results thus far (works on 2/3 of cancer cells - up to 99% metastatic cancer)
///About to release Phase 3 interim results (Head and Neck)
////Synergistic with just about every chemo drug and radiation ( think 1+1 = 4)
//Side effects are "mild flu like symptoms" for 2-3 days
//Could be approved in 2013
(and Yes, I own some shares)
Zel
2012-09-01 02:17:33 PM
3 votes:
Lots of people work with viruses in medical research. Theyre a useful avenue to injecting particular cells with new genes or behaviors. The reason the cure for cancer never comes easily is that cancer is not one disease, but any of a billion ways for normal cells to go haywire. We're learning all about cell growth and normal behavior during cancer research. When we can control cells completely its going to be a lot more awesome than just a cancer cure.
2012-09-01 03:32:35 PM
2 votes:

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Yup. All those glorious ten-thousandaire lab techs are sitting on the data because they like collecting food stamps.

/As a manager, we saw people in other labs selling data about how new experimental designs worked for new ipads and crap. Do you really think the people who do the work of the science would stay close mouthed about this shiat?
2012-09-01 02:27:23 PM
2 votes:

AccuJack: Another example of how the American government, forming its laws around and to support big business in certain areas, has made opportunities for other organizations doing the same thing any other way disappear.


And all the more sinister- American laws have reached all the way to SWEDEN. Why isn't that the headline?

TofuTheAlmighty: I was already skeptical of the article's premise but this shreds the author's crediblility.


The article is mostly bullshiat. The guy has a potentially promising viral cancer treatment, like a thousand other medical researchers. That's fine and all, but it's hardly some inditement of modern society that he's not getting funded.

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Because the person with a cure for a wide variety of cancers isn't going to be able to name their price, right? There will never be a cure for cancer because cancer is not a single thing, it's not a single disease, and the pathology of each kind of cancer is very different relative to another kind. It's complex, it's difficult, and it takes a long time to go from, "hey, this works in a petri dish!" to "wait, I think we have an actual treatment here."

Also: £1,000,000 to get to medical trials? I think somebody's severely underestimating the costs, or the journalist completely screwed up on the currency conversion.
2012-09-01 08:04:05 PM
1 votes:

marcusdmc: Isn't this how the movie "I Am Legend" begins?


Yes. Fortunately, that's what they call fiction.
Just another in a long line of movies that reflect people worrying about new technology and scientific knowledge that they don't understand.


ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Oh for fark's sake, of course there is. It just has to be patent-able.
Don't you think any pharmaceutical company would like, not only to be the one that invented the cure for cancer (and be paid for all those treatments), but to also immediately render all their competitors lesser cancer treatments obsolete? It's not like they need to worry about running out of patients, people aren't going to stop getting cancer.
2012-09-01 06:06:08 PM
1 votes:

Amos Quito: ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Indeed, and they will do anything and everything to protect their golden-egg laying goose.


The Nutraceutical Barons certainly sleep better at night knowing their snake oil can still sell false hope.
2012-09-01 05:33:17 PM
1 votes:
I think we're all missing the most important thing here:

i.telegraph.co.uk

The doctor is hot.
2012-09-01 05:10:53 PM
1 votes:
Did the author of this column have a minimum word quota he had to fill? There is so much noncontributing detritus in the article I couldn't follow the main idea. Thank _______ for Fark comments. What happened to "brevity is the soul of wit"?
2012-09-01 05:06:16 PM
1 votes:

Crotchrocket Slim: LabGrrl: ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.

Yup. All those glorious ten-thousandaire lab techs are sitting on the data because they like collecting food stamps.

/As a manager, we saw people in other labs selling data about how new experimental designs worked for new ipads and crap. Do you really think the people who do the work of the science would stay close mouthed about this shiat?

Researchers and not CEOs make budgetary decisions on what gets funded these days?


Oh, so your theory is that the CEOs have magic mirrors that only allow them to fund the research that they know doesn't work...and that the researchers and lab personnel are so clueless they don't know that the stuff they are doing has already been proven to not work?

How does that work?

No, really, how does that work. I totally want to know.

/Disregarding the fact that most grants and funding sources let you switch techniques and even compounds under study without needing to rewrite them completely...some you don't even need to file an amendment.
2012-09-01 04:58:01 PM
1 votes:
Dear conspiracy theorists,

Rigorous testing and review of new drugs and medical treatments is a good thing.
2012-09-01 04:55:25 PM
1 votes:

AccuJack: Another example of how the American government, forming its laws around and to support big business in certain areas, has made opportunities for other organizations doing the same thing any other way disappear. Like US auto makers made immune from threats from startup car companies, or any other business with a ridiculously high regulatory barrier for entry.

Everyone likes to believe the reason we haven't found a cure for cancer is that no one's discovered it. The truth is, no one knows a way to make it pay for its own development because the American health care business is fossilized into one very profitable business model that the government won't change for fear of losing its income stream.


See, the problem that I have with this statement is that its glaringly obvious that you don't personally know a single scientist in your life. So let me help you out. I do, and your statement is absurd on its face. Thousands of researchers slave away for 60-80 hours a week with often shaky career prospects trying to advance human knowledge in this dark corner of science by a tiny, tiny sliver. Often the disappointments far outweigh the victories because cancers are a collection of very ingenious and difficult to treat diseases that use our own bodies highly evolved mechanisms against us and constantly change. And at the end of it all, after the small hard fought victories give over many years some people hope for alleviation of their pain, it all gets called a conspiracy theory. If your theory holds any weight, name the ways that anyone "has made opportunities for other organizations doing the same thing any other way disappear" or that someone has discovered a cure. Enlighten us.
2012-09-01 04:33:55 PM
1 votes:

Oznog: Billy Bathsalt: I sped-read that about half-way through. That surely was a wall o' text. I didn't get to the part that explains why he didn't email Steve Jobs and tell him about the good news.

No farking kidding. Rambling lengths of text detailing irrelevant thoughts does not build drama.


No joke? After the third or fourth "but why isn't a trial starting" followed by useless thoughts, I gave up.
2012-09-01 04:24:55 PM
1 votes:
Penn University is using dormant-HIV-reprogrammed-to-target-cancer-cells to cure cancer.

They wrote about it last year or so.

Link

Still in clinical trials IIRC.
2012-09-01 03:27:37 PM
1 votes:

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Uh huh, there's no money in a cure that costs next to nothing and has a 90+% success rate. No one could possibly make money off that.

Do you people know how stupid you sound?
2012-09-01 03:26:10 PM
1 votes:
VSV shakes it's tiny, bacterial fists in rage.
2012-09-01 03:21:10 PM
1 votes:
Drew has $1million.

He could have the cancer cure named, "Fark you Cancer"
2012-09-01 03:04:50 PM
1 votes:

Crotchrocket Slim: antibiotic-resistant superviruses


ummm.. viruses have always been antibiotic-resistant. Anitbiotics target bacteria.

/nitpicks, I has them
2012-09-01 03:02:49 PM
1 votes:

TexasPeace: 'horseradish peroxidase conjugated donkey anti-goat antibody'. ??


This is basically just a thing used to detect whether or not (and in what approximate amount) something (let's call it POOP, here, 'cause that amuses me) is present in a sample.

1) "horseradish peroxidase conjugated": http://en.wikipedia.org/wiki/Horseradish_peroxidase (tl;dr version: HP gets attached to the antibody to make it easier to detect)
2) "donkey anti-goat antibody": antibodies (for these/similar purposes) are produced using two species--first a goat (the goat antibodies target POOP), then a donkey (the donkey antibodies target the goat antibodies).
In this case, they took a sample of the thing they want to look for, or POOP, injected it into a goat. The goat's immune system, upon finding POOP in its body, produces antibodies that target POOP (it's more complex than that, but let's keep it simple). By drawing out some of the goat's blood, you can then obtain some antibodies that will bind to POOP. That's all well and good, but the goat antibodies, by themselves, aren't going to let you actually detect POOP in a lab experiment (they're just going to bind and do their thing), so they take the goat antibodies and inject them into a different species--in this case, a donkey. The donkey's immune system finds the goat antibodies and produces its own antibodies to target those goat antibodies (i.e., "donkey anti-goat antibodies"). Repeat the serum removal/extraction and you can get donkey antibodies targeting the goat antibodies. The donkey antibodies can then have horseradish peroxidase (or similar stuff) attached to them to make it more detectable. Then you can take a lab sample that may or may not contain POOP, add some of the goat antibodies that will bind to the POOP, then add some of the donkey antibodies that will bind to goat antibodies, then use science stuff to figure out how much POOP was present.

Probably more of an explanation than you were looking for, but science is fun and the techniques and ways people have figured out how to get around technical limitations are kinda cool.
2012-09-01 03:01:44 PM
1 votes:

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.



Indeed, and they will do anything and everything to protect their golden-egg laying goose.
2012-09-01 02:42:17 PM
1 votes:
How are we not discussing the claim that 29-year-old Dr. Justyna Leja looks like Scarlett Johansson. Didn't anyone read the article?!
2012-09-01 02:41:35 PM
1 votes:
'horseradish peroxidase conjugated donkey anti-goat antibody'. ??
2012-09-01 02:30:32 PM
1 votes:

AccuJack: Another example of how the American government, forming its blah, blah, blah...

Everyone likes to believe the reason we haven't found a cure for cancer is that no one's discovered it. The truth is, no one knows a way to make it pay for its own development because the American blah, blah, blah.


It's a shame there are not other countries in the world with intelligent scientists.
2012-09-01 02:28:39 PM
1 votes:
Zel typed to appear above,
When we can control cells completely its going to be a lot more awesome than just a cancer cure.
When that happens, it might be the semi-automagic answer to many of the medical woes, very least.
2012-09-01 02:24:31 PM
1 votes:

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Reminds me of that scene from the All-Star Superman film where Lex Luthor develops a cure for tuberculosis (or was that cancer? been a while since I saw the movie) but sits on it because he wants to develop a life-long treatment for it to sell to the public. I swear drug companies are all run by IRL Luthors (albeit not anywhere nearly as brilliant).
2012-09-01 02:17:31 PM
1 votes:

FTFA:

Keep an eye on what the quacks are saying, and you have an idea of what might be promising at the Wild West frontier of medicine.
I was already skeptical of the article's premise but this shreds the author's crediblility.
2012-09-01 02:10:10 PM
1 votes:
Uh yeah once every ten years this story has surfaced since the 80's. *shakes head..
2012-09-01 02:09:59 PM
1 votes:
I sped-read that about half-way through. That surely was a wall o' text. I didn't get to the part that explains why he didn't email Steve Jobs and tell him about the good news.
2012-09-01 02:04:45 PM
1 votes:
The Uppsala virus isn't unique. Since the 1880s, doctors have known that viral infections can cause dramatic reductions in tumours. In 1890 an Italian clinician discovered that prostitutes with cervical cancer went into remission when they were vaccinated against rabies, and for several years he wandered the Tuscan countryside injecting women with dog saliva. In another, 20th-century, case, a 14-year-old boy with lymphatic leukaemia caught chickenpox: within a few days his grotesquely enlarged liver and spleen had returned to ordinary size; his explosive white blood cell count had shrunk nearly 50-fold, back to normal.


If this has been known for 130 years, then Dr. Essand can't be the only guy in the world pursuing a viral cure for cancer. Surely there must be other teams and other companies doing this. It seems unlikely that this one guy is the only scientist on the planet exploring this.
2012-09-01 02:03:24 PM
1 votes:
And when your immune system begins producing antibodies to this virus... ?
2012-09-01 02:00:11 PM
1 votes:
So for sensationalistic journalo-crap this is not too bad.
2012-09-01 01:58:09 PM
1 votes:
One of these stories again.. I'll be back in 10 years and see if there is a followup..
2012-09-01 01:26:05 PM
1 votes:
Sadly, no kickstarter yet?
 
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