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(Telegraph)   Cure for cancer found. Still no cure for ... oh wait   (telegraph.co.uk) divider line 121
    More: Cool, liver cancer, cancer types, cell lines, theses, Amgen, Uppsala, neuroendocrine cancer, rare disease  
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25064 clicks; posted to Main » on 01 Sep 2012 at 1:51 PM (2 years ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2012-09-01 01:26:05 PM  
Sadly, no kickstarter yet?
 
2012-09-01 01:54:16 PM  
This is the first and probably last time we'll ever hear about this.
 
2012-09-01 01:57:18 PM  
Isn't this how the movie "I Am Legend" begins?
 
2012-09-01 01:57:34 PM  
Seen it.

upload.wikimedia.org
 
2012-09-01 01:58:09 PM  
One of these stories again.. I'll be back in 10 years and see if there is a followup..
 
2012-09-01 01:58:45 PM  
He just needs funding to cure cancer? Too bad The Oatmeal is raising money to build a goddamn Tesla museum. Otherwise, we could find out if he believes cancer bad.
 
2012-09-01 01:58:54 PM  
'Not "eliminates"! Not "invented", no!'

No. He said, "no".
 
2012-09-01 02:00:11 PM  
So for sensationalistic journalo-crap this is not too bad.
 
2012-09-01 02:01:53 PM  
So a good way to battle cancer is to work with children or become a flight attendant. Both occupations plunge you into cesspits of virii.
 
2012-09-01 02:02:00 PM  
there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.
 
2012-09-01 02:03:24 PM  
And when your immune system begins producing antibodies to this virus... ?
 
2012-09-01 02:04:45 PM  
The Uppsala virus isn't unique. Since the 1880s, doctors have known that viral infections can cause dramatic reductions in tumours. In 1890 an Italian clinician discovered that prostitutes with cervical cancer went into remission when they were vaccinated against rabies, and for several years he wandered the Tuscan countryside injecting women with dog saliva. In another, 20th-century, case, a 14-year-old boy with lymphatic leukaemia caught chickenpox: within a few days his grotesquely enlarged liver and spleen had returned to ordinary size; his explosive white blood cell count had shrunk nearly 50-fold, back to normal.


If this has been known for 130 years, then Dr. Essand can't be the only guy in the world pursuing a viral cure for cancer. Surely there must be other teams and other companies doing this. It seems unlikely that this one guy is the only scientist on the planet exploring this.
 
2012-09-01 02:06:28 PM  

EggSniper: Seen it.

[upload.wikimedia.org image 220x325]


STOP STEALING MY THOUGHTS
 
2012-09-01 02:08:39 PM  
Another example of how the American government, forming its laws around and to support big business in certain areas, has made opportunities for other organizations doing the same thing any other way disappear. Like US auto makers made immune from threats from startup car companies, or any other business with a ridiculously high regulatory barrier for entry.

Everyone likes to believe the reason we haven't found a cure for cancer is that no one's discovered it. The truth is, no one knows a way to make it pay for its own development because the American health care business is fossilized into one very profitable business model that the government won't change for fear of losing its income stream.
 
2012-09-01 02:09:59 PM  
I sped-read that about half-way through. That surely was a wall o' text. I didn't get to the part that explains why he didn't email Steve Jobs and tell him about the good news.
 
2012-09-01 02:10:10 PM  
Uh yeah once every ten years this story has surfaced since the 80's. *shakes head..
 
2012-09-01 02:14:28 PM  
On the snow-clotted plains of central Sweden where Wotan and Thor, the clamorous gods of magic and death

Thats so Wednesday and Thursday

Wait. Wednesday's magic? Needs that special Wednesday underwear right now.
 
2012-09-01 02:17:31 PM  

FTFA:

Keep an eye on what the quacks are saying, and you have an idea of what might be promising at the Wild West frontier of medicine.
I was already skeptical of the article's premise but this shreds the author's crediblility.
 
Zel
2012-09-01 02:17:33 PM  
Lots of people work with viruses in medical research. Theyre a useful avenue to injecting particular cells with new genes or behaviors. The reason the cure for cancer never comes easily is that cancer is not one disease, but any of a billion ways for normal cells to go haywire. We're learning all about cell growth and normal behavior during cancer research. When we can control cells completely its going to be a lot more awesome than just a cancer cure.
 
2012-09-01 02:23:39 PM  
FTA:
"In 1890 an Italian clinician discovered that prostitutes with cervical cancer went into remission when they were vaccinated against rabies"

Jesus, them's some rough hookers when they have to vaccinated against rabies...
 
2012-09-01 02:24:31 PM  

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Reminds me of that scene from the All-Star Superman film where Lex Luthor develops a cure for tuberculosis (or was that cancer? been a while since I saw the movie) but sits on it because he wants to develop a life-long treatment for it to sell to the public. I swear drug companies are all run by IRL Luthors (albeit not anywhere nearly as brilliant).
 
2012-09-01 02:25:50 PM  

Hector Remarkable: 'Not "eliminates"! Not "invented", no!'

No. He said, "no".



But doesn't that make it legitimate?

/so confused
 
2012-09-01 02:27:23 PM  

AccuJack: Another example of how the American government, forming its laws around and to support big business in certain areas, has made opportunities for other organizations doing the same thing any other way disappear.


And all the more sinister- American laws have reached all the way to SWEDEN. Why isn't that the headline?

TofuTheAlmighty: I was already skeptical of the article's premise but this shreds the author's crediblility.


The article is mostly bullshiat. The guy has a potentially promising viral cancer treatment, like a thousand other medical researchers. That's fine and all, but it's hardly some inditement of modern society that he's not getting funded.

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Because the person with a cure for a wide variety of cancers isn't going to be able to name their price, right? There will never be a cure for cancer because cancer is not a single thing, it's not a single disease, and the pathology of each kind of cancer is very different relative to another kind. It's complex, it's difficult, and it takes a long time to go from, "hey, this works in a petri dish!" to "wait, I think we have an actual treatment here."

Also: £1,000,000 to get to medical trials? I think somebody's severely underestimating the costs, or the journalist completely screwed up on the currency conversion.
 
2012-09-01 02:28:25 PM  

vudukungfu: Sadly, no kickstarter yet?


Came to say this. It would take a day for all kickstarter records to be shattered.
 
2012-09-01 02:28:39 PM  
Zel typed to appear above,
When we can control cells completely its going to be a lot more awesome than just a cancer cure.
When that happens, it might be the semi-automagic answer to many of the medical woes, very least.
 
2012-09-01 02:30:32 PM  

AccuJack: Another example of how the American government, forming its blah, blah, blah...

Everyone likes to believe the reason we haven't found a cure for cancer is that no one's discovered it. The truth is, no one knows a way to make it pay for its own development because the American blah, blah, blah.


It's a shame there are not other countries in the world with intelligent scientists.
 
2012-09-01 02:35:54 PM  
Man, if Fark could raise 1 million pounds, he'd have to name it the Fark Virus...
Or maybe he would take requests (for a million pounds I would!) and he would call it the UFIA Virus.
 
2012-09-01 02:40:56 PM  
Hurry up with this, please.
 
2012-09-01 02:41:35 PM  
'horseradish peroxidase conjugated donkey anti-goat antibody'. ??
 
2012-09-01 02:42:04 PM  

Lord Huggington: This is the first and probably last time we'll ever hear about this.


If, like bleach, fire, exposure to extreme cold, etc., it only can kill cancer cells in a culture flask, then, yes, this will be the last time we ever hear of it.

/I can kill cancer cells with my fingertips
//So can you
///Problem is getting them separated from all the other cells and/or not killing off the non-cancer cells
 
2012-09-01 02:42:17 PM  
How are we not discussing the claim that 29-year-old Dr. Justyna Leja looks like Scarlett Johansson. Didn't anyone read the article?!
 
2012-09-01 02:43:10 PM  

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Yes, there is absolutely no money curing a disease which is diagnosed in millions of people a year, particularly for the companies which aren't involved in the treatment of cancer.
 
2012-09-01 02:45:25 PM  

Crotchrocket Slim: ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.

Reminds me of that scene from the All-Star Superman film where Lex Luthor develops a cure for tuberculosis (or was that cancer? been a while since I saw the movie) but sits on it because he wants to develop a life-long treatment for it to sell to the public. I swear drug companies are all run by IRL Luthors (albeit not anywhere nearly as brilliant).


Do you know how much money drug companies make on antibiotics?
 
2012-09-01 02:48:33 PM  

meanmutton: Crotchrocket Slim: ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.

Reminds me of that scene from the All-Star Superman film where Lex Luthor develops a cure for tuberculosis (or was that cancer? been a while since I saw the movie) but sits on it because he wants to develop a life-long treatment for it to sell to the public. I swear drug companies are all run by IRL Luthors (albeit not anywhere nearly as brilliant).

Do you know how much money drug companies make on antibiotics?


You mean those things that are over-prescribed to the point that we're seeing antibiotic-resistant superviruses we effectively have no treatment for now?
 
2012-09-01 02:55:17 PM  
I'll just leave this here....
Oncolytics Biotech - Reolysin

/Naturally occurring Reovirus (Not modified)
//Incredible results thus far (works on 2/3 of cancer cells - up to 99% metastatic cancer)
///About to release Phase 3 interim results (Head and Neck)
////Synergistic with just about every chemo drug and radiation ( think 1+1 = 4)
//Side effects are "mild flu like symptoms" for 2-3 days
//Could be approved in 2013
(and Yes, I own some shares)
 
2012-09-01 03:01:44 PM  

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.



Indeed, and they will do anything and everything to protect their golden-egg laying goose.
 
2012-09-01 03:02:49 PM  

TexasPeace: 'horseradish peroxidase conjugated donkey anti-goat antibody'. ??


This is basically just a thing used to detect whether or not (and in what approximate amount) something (let's call it POOP, here, 'cause that amuses me) is present in a sample.

1) "horseradish peroxidase conjugated": http://en.wikipedia.org/wiki/Horseradish_peroxidase (tl;dr version: HP gets attached to the antibody to make it easier to detect)
2) "donkey anti-goat antibody": antibodies (for these/similar purposes) are produced using two species--first a goat (the goat antibodies target POOP), then a donkey (the donkey antibodies target the goat antibodies).
In this case, they took a sample of the thing they want to look for, or POOP, injected it into a goat. The goat's immune system, upon finding POOP in its body, produces antibodies that target POOP (it's more complex than that, but let's keep it simple). By drawing out some of the goat's blood, you can then obtain some antibodies that will bind to POOP. That's all well and good, but the goat antibodies, by themselves, aren't going to let you actually detect POOP in a lab experiment (they're just going to bind and do their thing), so they take the goat antibodies and inject them into a different species--in this case, a donkey. The donkey's immune system finds the goat antibodies and produces its own antibodies to target those goat antibodies (i.e., "donkey anti-goat antibodies"). Repeat the serum removal/extraction and you can get donkey antibodies targeting the goat antibodies. The donkey antibodies can then have horseradish peroxidase (or similar stuff) attached to them to make it more detectable. Then you can take a lab sample that may or may not contain POOP, add some of the goat antibodies that will bind to the POOP, then add some of the donkey antibodies that will bind to goat antibodies, then use science stuff to figure out how much POOP was present.

Probably more of an explanation than you were looking for, but science is fun and the techniques and ways people have figured out how to get around technical limitations are kinda cool.
 
2012-09-01 03:04:50 PM  

Crotchrocket Slim: antibiotic-resistant superviruses


ummm.. viruses have always been antibiotic-resistant. Anitbiotics target bacteria.

/nitpicks, I has them
 
2012-09-01 03:12:28 PM  
I can think of a pretty easy source of investment that isn't worried about big payouts, only results. People dying of cancer who will all too soon have no use for any of their money.

If you have a cure that "the man" won't let you use then GO SOMEWHERE ELSE. You find some banana republic and make it the new cancer treatment capitol of the world, you don't sit on it for years lamenting your lack of corporate investors or public grants.
 
2012-09-01 03:21:10 PM  
Drew has $1million.

He could have the cancer cure named, "Fark you Cancer"
 
2012-09-01 03:24:35 PM  

vudukungfu: Sadly, no kickstarter yet?


TheSwizz: vudukungfu: Sadly, no kickstarter yet?

Came to say this. It would take a day for all kickstarter records to be shattered.


Yeah. These doctors aren't very bright. Quite frankly, neither is the reporter, if everything they say is true. It should be trivial to get a million pounds for a working cure for cancer.

I'm thinking someone involved is full of shiat.
 
2012-09-01 03:26:10 PM  
VSV shakes it's tiny, bacterial fists in rage.
 
2012-09-01 03:27:37 PM  

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Uh huh, there's no money in a cure that costs next to nothing and has a 90+% success rate. No one could possibly make money off that.

Do you people know how stupid you sound?
 
2012-09-01 03:28:40 PM  
um, until I got sick (my immune system is run amok, it will kill cancer just fine. It also eats healthy cells, which is the problem) I worked for large cancer research institute which will remain nameless (but if you do tissue culture you have media with our old initials on it ) and about every 4th lab was doing what most people would consider a variation on this...it's not unstudied.

...and about half of what was left were doing variations on turning immune systems into mine...which is scary...and I can go tinfoil hat about it if I'm on the right drugs.

/HRP is oldschool. I like antibodies conjugated to proprietary fluorescent molecules.
//You can take my 4-color fluorescent western blot from my cold, dead hands.
 
2012-09-01 03:32:35 PM  

ltdanman44: there is no money involved in a cure. Cancer treatment is a multi-billion dollar industry.


Yup. All those glorious ten-thousandaire lab techs are sitting on the data because they like collecting food stamps.

/As a manager, we saw people in other labs selling data about how new experimental designs worked for new ipads and crap. Do you really think the people who do the work of the science would stay close mouthed about this shiat?
 
2012-09-01 03:35:25 PM  

chupathingie: Crotchrocket Slim: antibiotic-resistant superviruses

ummm.. viruses have always been antibiotic-resistant. Anitbiotics target bacteria.

/nitpicks, I has them


Hey what can I say I work in IT. Got issues with Windows or OS X?
 
2012-09-01 03:36:23 PM  

t3knomanser: The article is mostly bullshiat. The guy has a potentially promising viral cancer treatment, like a thousand other medical researchers. That's fine and all, but it's hardly some inditement of modern society that he's not getting funded.


Assuming the £1-2M figure is in the right ballpark, you could have funded hundreds of thousands of trials for the cost of the Iraq war.
 
2012-09-01 03:38:45 PM  

CowardlyLion: TexasPeace: 'horseradish peroxidase conjugated donkey anti-goat antibody'. ??

This is basically just a thing used to detect whether or not (and in what approximate amount) something (let's call it POOP, here, 'cause that amuses me) is present in a sample.

1) "horseradish peroxidase conjugated": http://en.wikipedia.org/wiki/Horseradish_peroxidase (tl;dr version: HP gets attached to the antibody to make it easier to detect)
2) "donkey anti-goat antibody": antibodies (for these/similar purposes) are produced using two species--first a goat (the goat antibodies target POOP), then a donkey (the donkey antibodies target the goat antibodies).
In this case, they took a sample of the thing they want to look for, or POOP, injected it into a goat. The goat's immune system, upon finding POOP in its body, produces antibodies that target POOP (it's more complex than that, but let's keep it simple). By drawing out some of the goat's blood, you can then obtain some antibodies that will bind to POOP. That's all well and good, but the goat antibodies, by themselves, aren't going to let you actually detect POOP in a lab experiment (they're just going to bind and do their thing), so they take the goat antibodies and inject them into a different species--in this case, a donkey. The donkey's immune system finds the goat antibodies and produces its own antibodies to target those goat antibodies (i.e., "donkey anti-goat antibodies"). Repeat the serum removal/extraction and you can get donkey antibodies targeting the goat antibodies. The donkey antibodies can then have horseradish peroxidase (or similar stuff) attached to them to make it more detectable. Then you can take a lab sample that may or may not contain POOP, add some of the goat antibodies that will bind to the POOP, then add some of the donkey antibodies that will bind to goat antibodies, then use science stuff to figure out how much POOP was present.

Probably more of an explanation than you were looking for, but science is fu ...


The only question is, why not conjugate the HRP directly to the goat antibodies? The reasons include amplification (several of the donkey antibodies can bind to a goat antibody amplifying the signal) and more importantly cost. There are brazillians of proteins out there that people have made antibodies to. If you go and spend the money to conjugate each one you're wasting money when you can just make conjugated antigoat, antirabbit, antirat, or antimouse antibodies that pretty much cover all your bases with only a few antisera.
 
2012-09-01 03:41:18 PM  
Kellis-Amberlee - the virus from this book


http://en.wikipedia.org/wiki/Feed_%28Grant_novel%29

Kellis-Amberlee cured cancer (all kinds) the common cold. Amazing triumph. Then the virus mutated. and all mammals above 40lbs turn to when they die. Solid research on microbiology, starts fast and keeps going.
 
2012-09-01 03:42:13 PM  
Phleghm_Flavored_Bubblegum: Kellis-Amberlee - the virus from this book


http://en.wikipedia.org/wiki/Feed_%28Grant_novel%29

Kellis-Amberlee cured cancer (all kinds) the common cold. Amazing triumph. Then the virus mutated. and all mammals above 40lbs turn to when they die. Solid research on microbiology, starts fast and keeps going.
 
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