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(NPR)   Oh, I'm being eaten/By a boa constrictor/A boa constrictor/I'm being eaten by a boa constrictor/And I don't like it--one bit/Well, what do you know?/It's nibblin' my toe./Oh, gee/It's up to my knee./Oh my/It gave me Ebola   (npr.org ) divider line
    More: Scary, ebola, UCSF, Taryn Hook, snakes, virus, knees  
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8414 clicks; posted to Main » on 14 Aug 2012 at 3:37 PM (3 years ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



39 Comments     (+0 »)
 
View Voting Results: Smartest and Funniest
 
2012-08-14 01:54:57 PM  
cias.rit.edu
 
2012-08-14 02:36:59 PM  
Wow, subby. Does THAT take me back to my childhood.
 
2012-08-14 03:40:02 PM  
Just glad it's not in the Frigidaire
 
2012-08-14 03:42:23 PM  
Arenaviruses are why I don't go to sporting events.
 
2012-08-14 03:44:12 PM  
FTA: "He likes American Idol."

Anthropomorphize much?
 
2012-08-14 03:47:01 PM  
i.imgur.com
 
2012-08-14 03:51:03 PM  
Long story made short. Snake is okay; owner not so much.
 
2012-08-14 03:51:21 PM  
"One of its genes is actually most closely related to the same gene in Ebola virus," he says. "So this virus is actually a mashup, or a genetic mix of arenaviruses and Ebola virus."

So, how does an African hemorrhagic fever virus have the chance to mash-up and find its way into new world boas?
 
2012-08-14 03:53:34 PM  
Get this in before it devolves into a boa constrictor pun page:

That's very interesting and now we must wonder if the latest Ebola outbreaks started from eating pythons instead of fruit bats, which were the previously unindicted carriers of filoviruses. Be scary if it was snakes all the time.
 
2012-08-14 03:54:25 PM  
I read a lot.

That's the weirdest thing I've ever read.
 
2012-08-14 04:01:59 PM  
to the tune of?
 
2012-08-14 04:02:04 PM  
People who keep snakes (or pretty much any reptile) as pets aren't right in the head....
 
2012-08-14 04:03:20 PM  
So it's not cool to have sex with snakes any more? Asking for a friend of mine...
 
2012-08-14 04:08:41 PM  

Carn: So it's not cool to have sex with snakes any more? Asking for a friend of mine...



Just not oral. Otherwise, you're golden.
 
2012-08-14 04:10:32 PM  
HMM, Cure for Floridas snake problems in everglades? nothing wrong with letting a mutated ebola virus free to roam around in that primordial swamp. Now to test it on pythons.


muah hah hah ahah (mad scientist laughter ensues)
 
2012-08-14 04:13:31 PM  

hobnail: "One of its genes is actually most closely related to the same gene in Ebola virus," he says. "So this virus is actually a mashup, or a genetic mix of arenaviruses and Ebola virus."

So, how does an African hemorrhagic fever virus have the chance to mash-up and find its way into new world boas?


We're learning that viruses infect hosts that aren't their primary targets all the time. If there happen to be two viruses that infect simultaneously, they can recombine and you get something else. Lots of work has been done looking at the immune history of African bush hunters and they often have been infected with tiger and monkey viruses much more frequently than we thought. They just can't reproduce well enough in humans to be transmitted from human to human.

In this work, it's impossible to say, though, because the viral family these come from is not well fleshed out enough to know whether they all have this gene, indicating ancestral inheritance, or whether only one or a few do, indicating recombination.

(CSB and full disclosure: I know Prof. Derisi and the grad student who did the work--they are both friends of mine, though I don't work in that particular lab)
 
2012-08-14 04:16:50 PM  
 
2012-08-14 04:20:01 PM  
----^ thank you sir.
 
2012-08-14 04:21:43 PM  

prometa: hobnail: "One of its genes is actually most closely related to the same gene in Ebola virus," he says. "So this virus is actually a mashup, or a genetic mix of arenaviruses and Ebola virus."

So, how does an African hemorrhagic fever virus have the chance to mash-up and find its way into new world boas?

We're learning that viruses infect hosts that aren't their primary targets all the time. If there happen to be two viruses that infect simultaneously, they can recombine and you get something else. Lots of work has been done looking at the immune history of African bush hunters and they often have been infected with tiger and monkey viruses much more frequently than we thought. They just can't reproduce well enough in humans to be transmitted from human to human.

In this work, it's impossible to say, though, because the viral family these come from is not well fleshed out enough to know whether they all have this gene, indicating ancestral inheritance, or whether only one or a few do, indicating recombination.

(CSB and full disclosure: I know Prof. Derisi and the grad student who did the work--they are both friends of mine, though I don't work in that particular lab)


I get all of that... the fact that this virus is related to the arenavirus is no surprise, given that rodents are the natural reservoir for arenaviruses, while at the same time comprising a large part of the diet of boas.

My question is how New World snakes get a virus that has close relations with an Old World virus (ebola).

Maybe it originated with Old World snakes and made the jump to boas in captivity?
 
2012-08-14 04:25:31 PM  

chevydeuce: People who keep snakes (or pretty much any reptile) as pets aren't right in the head....


Why not? Does that also include people who keep birds or fish?
 
2012-08-14 04:26:37 PM  
Coming this October from SYFY
BOLABOA.
 
2012-08-14 04:26:58 PM  

chevydeuce: People who keep snakes (or pretty much any reptile) as pets aren't right in the head....


^^That!!!^^
 
2012-08-14 04:28:35 PM  

SwingDancer: HMM, Cure for Floridas snake problems in everglades? nothing wrong with letting a mutated ebola virus free to roam around in that primordial swamp. Now to test it on pythons.


muah hah hah ahah (mad scientist laughter ensues)


GET OUT OF MY HEAD
 
2012-08-14 04:34:15 PM  
I love Shshelel Silverstein.

...Oh heck, it's up to my neck!
...Oh dread, it's up to my mrrpphwerrgg...
 
2012-08-14 04:42:48 PM  
Subby, I am giving you Internet hugs because you made my freaking day.

/Shel Silverstein is my favorite poet EVER.
 
2012-08-14 04:44:57 PM  

SecretAgentWoman: I love Shshelel Silverstein.

...Oh heck, it's up to my neck!
...Oh dread, it's up to my mrrpphwerrgg...


Did you just have a stroke?
/Shel is awesome. Vital for any awesome childhood.
 
2012-08-14 04:45:53 PM  

chevydeuce: People who keep snakes (or pretty much any reptile) as pets aren't right in the head....


FTFA: "Larry (the snake) is a member of the family in every respect," she says. "He gets in bed with us and watches television. He likes American Idol."

/SSSSSeacrest, out!
 
2012-08-14 04:46:19 PM  
Link

Everybody loves a nut...
 
2012-08-14 05:07:57 PM  
What does Rocky BalBoa have to say about all this.
 
2012-08-14 05:44:53 PM  
subby needs to know that snakes eat their prey head first. It reduces complications.
 
2012-08-14 05:46:01 PM  
Wow, that really brings me back. I didn't know it was a poem. I only knew it as a song on a children's album by (I thought) Pete Seeger.

♫ Oh fiddle, it's up to my middle. ♫
♫ Oh dread, it's up to my...

img819.imageshack.us

Thanks for ruining my childhood memories, Subby.
 
2012-08-14 06:08:09 PM  

WordsnCollision: chevydeuce: People who keep snakes (or pretty much any reptile) as pets aren't right in the head....

FTFA: "Larry (the snake) is a member of the family in every respect," she says. "He gets in bed with us and watches television. He likes American Idol."


That wasn't the snake dear...
 
2012-08-14 06:13:07 PM  
Wasn't that performed by Charlotte Diamond?

/takes me back too, man.
 
2012-08-14 06:42:03 PM  
Can we use this disease to help save the everglades in Florida?
http://www.nydailynews.com/news/national/monstrous-17-foot-python-dis c overed-florida-everglades-carrying-87-fertilized-eggs-article-1.113581 0
 
2012-08-14 09:54:28 PM  
Oh god, I remember my 1st grade teacher Sr. Luke singing a version of that with her autoharp.

Well done subby, well done.
 
2012-08-14 11:16:40 PM  
I'll tell you where I heard that before...

i.ebayimg.com
 
2012-08-14 11:22:03 PM  
Or, if you like the whole collection...

upload.wikimedia.org
 
2012-08-15 02:07:32 AM  
When your skin is several times shinier then the scaly reptile you're holding, you just might have some sort of condition yourself.
 
2012-08-15 09:01:53 AM  
Prediction of future Fark headline: Florida's attempt to reduce wild boa population with virus jumps the shark and other species barriers.
 
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