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(BBC)   Medical ethicists say baby-making with 2 women and 1 man is just dandy   (bbc.co.uk) divider line 202
    More: Spiffy, IVF, Wellcome Trust, bioethics, human culture, mitochondrial disorder, mitochondrial DNA, social benefits, Newcastle University  
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20223 clicks; posted to Main » on 12 Jun 2012 at 2:39 PM   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2012-06-12 04:16:45 PM
I have been there and I have done that, and dandy is an understatement.

That being said, the article is a lot less hot than I was expecting.
 
2012-06-12 04:22:02 PM
now lets try making a baby out of 12 vagrants from the public library
 
2012-06-12 04:22:35 PM
And the fearmongers once again demonstrate their total ignorance of biology, or at least, their willingness to exploit same in others.

"Designer babies?" ... do they know what mitochondira actually are, and why Jurassic Park was FICTION?
 
gja [TotalFark]
2012-06-12 04:24:24 PM
HumbertoEcho: www.eatnineghost.com
You guys are slipping. They are legal since a few years already.... :-)



WOW! You could have the frank AND bean worked at the same time, and only have to buy 1 dinner!
 
2012-06-12 04:24:24 PM
ParaHandy: And the fearmongers once again demonstrate their total ignorance of biology, or at least, their willingness to exploit same in others.

"Designer babies?" ... do they know what mitochondira actually are, and why Jurassic Park was FICTION?


They're hoping to get their baby made by coach, or some other bag maker
 
2012-06-12 04:24:51 PM
CrispFlows: Isn't what's wrong with eugenics the concept of racial purity? THAT's the ethical flaw, not the 'controlled breeding' .

The strict definition of eugenics is the practice of improving the genetic composition of a population. In that sense even the removal of genetic defects and diseases from a population is eugenics because you would effectively be 'improving' the genetics of the population.

But no one really has an issue with that. It's when that improvement moves to non-health related characteristics that people start to get squeamish.
 
2012-06-12 04:25:56 PM
fozziewazzi: But no one really has an issue with that. It's when that improvement moves to non-health related characteristics that people start to get squeamish.

If you think about it, that's a pretty good point of where to draw the line.
 
2012-06-12 04:26:08 PM
I wouldn't mind but there's some local guy who works on the garbage truck. He has multiple children by multiple girlfriends. He and the girlfriends look about how you'd expect, all on the public dole.
This guy we did not need 7 more of.
/that number may be low.
 
2012-06-12 04:26:34 PM
gja: WOW! You could have the frank AND bean worked at the same time, and only have to buy 1 dinner!

I'm laughing. I shouldn't be, but I am.
 
2012-06-12 04:30:39 PM
Gaseous Anomaly: Joce678: Do you have any idea how difficult it is to adopt a human child?

Healthy white baby? 7 years? What else you got?


I got two Koreans and a negra born with his heart on the outside.
 
2012-06-12 04:31:31 PM
ialdabaoth: downstairs: serpent_sky: There's also EXTREMELY high standards for adoption

^^^This. Its a nightmare. An acquantence of mine, my sister's best friend and her husband have been trying to adobt for YEARS. I totally applaud them for keeping up with the BS... but some people don't have the mental fortitude to do so.

Its not like there's a bank of kids witout homes, where you can visit some website and "add to cart".

Only if you care about the kid's race.


They don't. Well, they don't as in they don't need the kid to be white. They are white, but specifically want to adopt a minority kid for all the right reasons... no one wants them.
 
2012-06-12 04:32:06 PM
zedster: tenton: zedster: well IVF with a surrogate already does this naturally (DNA from dad and mom, mDNA from the surrogate mother) now they just want to find away to implant the mDNA and have the DNA mother do the birth

Since when? I'm pretty sure mDNA comes from the biological mother's genes, not imparted during the gestational period.

Looks like I am wrong, it is the newer IVF they are discussing in this article of using the DNA from one egg with the shell of another that causes this.

I swear I did read of case before this where the surrogates mtDNA was passed on. Cannot find any such info now


well the mDNA comes from the mitochondrial DNA present in the egg that gets fertilized so I cant see anyway that DNA from the surrogate would get imparted. you are prolly just mashing together some bits of information from similar stories. something about antibodies perhaps?

anyway, this is realllllly cool and could have the potential for some huge advances in getting genetic diseases out of the gene pool
 
2012-06-12 04:33:58 PM
Mugato: God's trying to give you a hint. We have too many people here already. Adopt.

If only someone could come up with a modest proposal...
 
2012-06-12 04:36:22 PM
epguides.com

/Approves
 
2012-06-12 04:38:39 PM
serpent_sky: serial_crusher: I object to fertility science in general.
If you have some biological fault that prevents you from producing healthy children, just go adopt some of the perfectly fine ones

There are some pretty rough adoption stories out there and a lot of adopted kids don't end up so well off, what with having to come to terms with biological parent(s) that didn't want them, often not knowing much, if anything, about their genetic background.,things like that. Plus, not everyone could love an adopted child like their own.

There's also EXTREMELY high standards for adoption, to the point that a good lot of people don't qualify, but anyone can go for fertility treatments as far as I know.

I know I would be a horrible parent (I don't like kids) and wouldn't be good at either. I resent people telling me how much I should want kids, so I'll extend the same courtesies I'd like extended to me to people desperate enough to have children that they spend tons of money and go through many emotionally difficult and medically invasive procedures to have them. And I certainly respect people who can, and do, adopt.


Utah

Utah and Florida are among the states that historically imposed more stringent restrictions of LGBT adoption. Utah prohibits adoption by "a person who is cohabiting in a relationship that is not a legally valid and binding marriage,"[69] making it legal for single people to adopt, regardless of sexual orientation, so long as they are not co-habitating in non-marital relationships.

Florida

In re: Gill

In Florida, adoption by homosexuals was expressly forbidden by a law passed by the 1977 Legislature, in the wake of the anti-gay Save Our Children campaign led by Anita Bryant. However, in November 2008, the law was struck down by state circuit court Judge Cindy Lederman in the case In re: Gill, involving a gay male couple raising two young foster children placed with them in 2004 by state child welfare workers.

In her ruling granting the adoption, Lederman found that the law violated the Florida Constitution's equal protection guarantees for the children and their adoptive parents; she added that there was no rational basis to prohibit gay parents from adopting, particularly since the scientific evidence of the suitability of gay parents is extensive, and the state allows them to act as foster parents.[70] The state appealed Judge Lederman's decision.

On September 22, 2010, the Third District Court of Appeals of the State of Florida unanimously upheld the decision of the lower court. On October 22 of that year, Attorney General Bill McCollum subsequently announced that the State of Florida would not appeal the court's ruling, thus ending the 33-year-old ban on gay adoptions in Florida.[71]

Arkansas

On November 4, 2008, Arkansas voters approved Act 1, a measure to ban anyone "co-habitating outside of a valid marriage" from being foster parents or adopting children. Although the law could apply to heterosexual couples, it was believed to have been written to target gay couples due to the fact that same-sex marriage is prohibited in that state, thereby making an adoption impossible.[72] Single gay men and lesbians were still allowed to adopt in Arkansas. The law was overturned on April 16, 2010 by state judge Chris Piazza.[73] The Arkansas Supreme Court upheld the lower court's decision on April 7, 2011.[74]

Louisiana

In December 2008, in the case of Adar v. Smith, a U.S. District Court in Louisiana "ordered the state registrar to honor the New York adoption of a baby boy by a same-sex couple, saying her continued failure to do so violated" the Full Faith and Credit Clause of the U.S. Constitution, and directed that the state issue a new birth certificate for the child listed both men as parents.[75]

However, the Attorney General of Louisiana appealed the decision, and on April 12, 2011, the Fifth Circuit Court of Appeals overturned the district court ruling, holding that "the full faith and credit clause does not oblige Louisiana to confer particular benefits on unmarried adoptive parents contrary to its law. . . . Louisiana has a right to issue birth certificates in the manner it deems fit."
 
2012-06-12 04:40:47 PM
Dr David King, the director of Human Genetics Alert, said: "Just as Frankenstein's creation was produced by sticking together bits from many different bodies, it seems that there is no grotesquerie, no violation of the norms of nature or human culture at which scientists and their bioethical helpers will balk.

Really? Dude has that much of a stick up his ass about the biological equivalent of installing a backup power supply in case the first one fails?

shiat, man, let's do this to _everyone_, it's not like multiple mitochondria are going to fight each other for supremacy or anything, they're largely immunologically neutral. If we assign multiple sets to every woman born from now on we'll never have to worry about any mitochondrial interaction issue again.

fozziewazzi: These women are practicing blatant eugenics and no one seems to really have a problem with it. But when people start talking about modifying genes directly for desirable traits for your offspring, ala 'Gattaca', suddenly that's a problem.

Well, there are two issues with direct genetic interference that differentiate it from simple statistical selection.

1- Guaranteed results vs statistical results. If you're just mixing genes as usual in a manner that will trend toward certain traits, you still have a lot of recessives and so on bouncing around that will provide an evolutionary 'backup' should something go wrong. If you're directly altering the code and the process becomes popular enough then you're in danger of creating a monoculture, which biologically is a synonym for "setting your species up to be wiped out by the next pathogen that comes along". Even "bad" genes like sickle-cell anemia have turned out to have positive effects in the past (a recessesive "carrier" for sickle-cell is significantly resistant to malaria) that we as scientists can get understandably leery of direct intervention even for the purpose of eliminating genetic disease.

Basically, we'd feel like right prats if we eliminated, say, MS completely from the gene pool and then it turned out that the partial (recessive) phenotype was the only thing keeping the bird flu from killing us all in the space of a weekend, and our knowledge of the biology of the entire planet isn't quite to the point we can guarantee that's not the case. So, while doing this on a small scale (as currently) isn't really an issue, we want to be edgy about the precedents we set for when human genetic fiddling really takes off.

2- Sociologically, we simply have to resolve at least some of the issues with people that are just so farking stupid they need an assistant (usually a congressional page) to tie their shoes in the morning. It would be nice to just ignore the bloody retards and go forward with beneficial research, but unfortunately a significant portion of society is made up of superstitious idiots who have to be calmly talked down from their paranoid fits for three to four decades before they'll stop blocking your research into umbrellas for fear of their shadow dying from dehydration.

We run into this with every new idea, and the solution, as with nuclear power, is to simply quietly educate the next generation as to the actual facts of the matter and wait for the congressmen, etc who side with the blatantly luddistic morons to die of old age/cancer/etc. Give it another 40 or 50 years and we can get back into Eugenics without the uninformed terrified bleating of the sheep disrupting the process. Though, obviously, we'll probably have to call it something other than eugenics because Israel will still have a huge lobby and those guys just won't let anything even vaguely associated with their nation's reason for existence go.

//I'm slightly less bitter about this than the above paragraph would indicate... slightly.
 
2012-06-12 04:44:28 PM
serpent_sky: serial_crusher: I object to fertility science in general.
If you have some biological fault that prevents you from producing healthy children, just go adopt some of the perfectly fine ones

There are some pretty rough adoption stories out there and a lot of adopted kids don't end up so well off, what with having to come to terms with biological parent(s) that didn't want them, often not knowing much, if anything, about their genetic background.,things like that. Plus, not everyone could love an adopted child like their own.

There's also EXTREMELY high standards for adoption, to the point that a good lot of people don't qualify, but anyone can go for fertility treatments as far as I know.

I know I would be a horrible parent (I don't like kids) and wouldn't be good at either. I resent people telling me how much I should want kids, so I'll extend the same courtesies I'd like extended to me to people desperate enough to have children that they spend tons of money and go through many emotionally difficult and medically invasive procedures to have them. And I certainly respect people who can, and do, adopt.


According to China, I'm too fat to adopt a baby from there. I'm serious.
 
2012-06-12 04:44:38 PM
cman: 2 girls

I like to think of this as 2 girls 1 schtup!
 
2012-06-12 04:47:11 PM
CrispFlows: fozziewazzi: But no one really has an issue with that. It's when that improvement moves to non-health related characteristics that people start to get squeamish.

If you think about it, that's a pretty good point of where to draw the line.


That's a line that will be impossible to enforce. Once genetic modification is safe and effective it will be done. Illegal in the U.S.? No problem. Fly to another country where they will gladly monkey with your genetic material to get the best the both of you can provide to your child. Once that ball gets rolling it will snowball. What parent wants their child competing against Übermensch?
 
2012-06-12 04:47:50 PM
loonatic112358: ParaHandy: And the fearmongers once again demonstrate their total ignorance of biology, or at least, their willingness to exploit same in others.

"Designer babies?" ... do they know what mitochondira actually are, and why Jurassic Park was FICTION?

They're hoping to get their baby made by coach


Coach? I guess it beats the back seat of a Volkswagen.
 
2012-06-12 04:53:47 PM
I_C_Weener: dletter: Of course... two women is hot and two guys is icky.

It's science, biatches!


Were balls touching?
 
2012-06-12 04:57:35 PM
Kurmudgeon: I wouldn't mind but there's some local guy who works on the garbage truck. He has multiple children by multiple girlfriends. He and the girlfriends look about how you'd expect, all on the public dole.
This guy we did not need 7 more of.
/that number may be low.



Something about your anecdote doesn't quite add up.
 
2012-06-12 05:02:14 PM
CrispFlows:

Isn't what's wrong with eugenics the concept of racial purity? THAT's the ethical flaw, not the 'controlled breeding' .


Historically, that's what caused it to lose favor among the general public. It had already fallen out of favor among biologists about 20 years earlier, because it is abject nonsense.
 
2012-06-12 05:02:50 PM
Biological Ali: serial_crusher: I object to fertility science in general.
If you have some biological fault that prevents you from producing healthy children, just go adopt some of the perfectly fine ones that need homes. Yes, even the black ones.

Wouldn't that apply to everyone? If there are kids that need adopting, adopt them instead of having your own - there's no logical reason to single out people who use just certain techniques for having children.


That's a good point, but I look at it from a money standpoint. If I can make a kid the easy and cheap way, I'll try that first.
But if I have to jump through a bunch of hoops and spend a bunch of money, might as well adopt at that point.
I also have ethical issues with the way IVF is implemented in most cases, making a bunch of embryos in a batch and then keeping most of them frozen in case the first few don't take (and then performing medical experiments on them if the other ones do take). Being a "life begins at conception" person, I can only support IVF if every embryo gets an equal chance.


Khellendros: serial_crusher: I object to fertility science in general.
If you have some biological fault that prevents you from producing healthy children, just go adopt some of the perfectly fine ones that need homes. Yes, even the black ones.

You're missing the issue with adoption. There are LOADS of people who want to adopt. Literally tens of thousands who are trying to adopt (through both state and private means). And there are tens of thousands of children in orphanages and temporary foster care. The problem is that the couples want infants, and the orphanages are filled with children that are 4+ years old. They have tons of mental issues, emotional issues, and physical problems.


I thought it was more specific, that people want white infants, but there are plenty of black and hispanic infants that go on to become 4+ year olds eventually. But I admit I haven't studied the problem in detail. So, sorry if I was incorrect.
 
2012-06-12 05:16:24 PM
125 posts and this is the first Giggity?
 
2012-06-12 05:20:32 PM
ArcadianRefugee: serpent_sky: There are some pretty rough adoption stories out there and a lot of adopted kids don't end up so well off, what with having to come to terms with biological parent(s) that didn't want them, often not knowing much, if anything, about their genetic background.,things like that. Plus, not everyone could love an adopted child like their own.

There's also EXTREMELY high standards for adoption, to the point that a good lot of people don't qualify, but anyone can go for fertility treatments as far as I know.

Everyone I know who has adopted did so from another country*: Guatemala, Russia, etc. None of them adopted from within the US because of how freakin' annoying it can be.

* [shakes baby rattle] THEY TOOK OUR JERBS!


It's really interesting that you mention overseas adoption:

a) Overseas adoption agencies and "Christian adoption agencies" in the US specialising in private adoptions tend to be the two areas where the old specter of baby farming crops up...only nowadays, they usually don't kill off the undesirable babies, but tend to adopt these out to parents who are pretty much ineligible otherwise to adopt. (Nowadays, this is probably best described as "baby mills".)

This is NOT to say all international adoption is like this, but unfortunately baby mills DO tend to be more common due to less regulation.

b) Guatemala in particular is an interesting case, because (as it turns out) dominionist baby mills catering to "white Christian families" overseas forced the effective shutdown of the entire international adoption program in Guatemala.

You see...there were rumours (so many that the US Department of State's travel advisories warned Americans not to be seen with Guatemalan kids in rural areas) that kids and babies were being stolen to adopt out to overseas prospective-parents...and it turned out there was a terrible, terrible truth to these rumours as kids were being adopted out in many cases without parental rights being terminated or parents even being told--typically they were told their children died in childbirth, or that they would be cared for whilst the parents got in better financial circumstances....and instead the kids would be adopted out to largely American "white Christian" households.

(Some of the same perpetrators who did this in Guatemala--who largely moved in after a massive earthquake in 1971--tried to do the same thing in Haiti after the horrid quake there, but fortunately there was a bit better awareness of international baby mills at this point.)

Of note--Guatemala seems to have been particularly popular because it wasn't a Hague Convention state until recently (the Hague Convention is an international treaty designed to allow children who are abducted or wrongfully taken from their parents to be returned quickly to their home country--you see it much more often in the context of international parental child abduction, but the Convention has provisions for state authorities to approve adoptions rather than the chain of notaries and apostilles that Guatemala formerly had) which functionally made it very easy for children to be wrongfully taken from their birth parents.

And yes, in the Guatemalan situation, it's ALREADY turning into a massive fustercluck as birth parents in Guatemala start suing for custody of their children from people who illegally adopted them from private agencies :P

Most of the countries with "desirable" children either tend to be from non-Hague Convention countries or are from East Asian countries with strong regional prejudice against adoption and/or sexual favouritism against boys (China is a hot-spot in particular for this, as is South Korea; the baby mills are pretty much run by the Chinese government in the first case, and by various dominionist charities and a very few legitimate ones in the other case); other countries (largely in the former Eastern Bloc) tend to restrict international adoption to what would be referred to as "special needs" children here, though this is often not well publicised in the US.

(And no, things aren't going to get better in this--apparently one of the major "baby mill" operators in Guatemala promptly set up shop in Ethiopia, which is becoming the "new hotness" in private international adoptions. :P)
 
2012-06-12 05:22:14 PM
serial_crusher: I thought it was more specific, that people want white infants, but there are plenty of black and hispanic infants that go on to become 4+ year olds eventually. But I admit I haven't studied the problem in detail. So, sorry if I was incorrect.

Even the irish ones?
 
2012-06-12 05:25:08 PM
TheShavingofOccam123: Utah and Florida are among the states that historically imposed more stringent restrictions of LGBT adoption.

The book Steven Petrow's Complete Gay & Lesbian Manners: The Definitive Guide to LGBT Life has a chapter dedicated to LBGT people looking to have kids (including by adoption). It's pretty helpful if it's something you're concerned about.
 
2012-06-12 05:27:28 PM
fozziewazzi: Once genetic modification is safe and effective it will be done. Illegal in the U.S.? No problem. Fly to another country where they will gladly monkey with your genetic material to get the best the both of you can provide to your child. Once that ball gets rolling it will snowball. What parent wants their child competing against Übermensch?

images.wikia.com

Intrigued.
 
2012-06-12 05:33:07 PM
How do they feel about two women and one cup?
 
2012-06-12 05:38:32 PM
gja: HumbertoEcho: [www.eatnineghost.com image 450x341]
You guys are slipping. They are legal since a few years already.... :-)



WOW! You could have the frank AND bean worked at the same time, and only have to buy 1 dinner!


I don't know what's stranger, the fact that HumbertoEcho was keeping tabs on her/their birthday or what it would be like to get a beej like that. One thing is for sure is that I'd have scrunchies on hand to tie up their hair. I'd want to see what's going on.
 
2012-06-12 05:43:23 PM
naughtyrev: How do they feel about two women and one cup?

depends whats in the cup is in coke or pepsi or *bleeaghhh* dr pepper
 
2012-06-12 05:43:36 PM
redonkulon: Just take the mitochondria from the father who presumably isn't a waster and mix it with the broken ones from the mother. The healthier mitochondirons will win out and then the merger is just from 2 parents and the ethicists can go back to lighting up their bongs.

I believe the mitochondria comes only from the mother. Maybe my cell biology information is wrong.
 
2012-06-12 05:51:14 PM
And in regards to the actual article (which involves nucleus transfer in the case of mitochondrial unwellness):

This is actually something I am glad the ethicists agreed was Perfectly OK, and for a number of reasons:

a) Mitochondrial disorders tend to lead to some rather nasty metabolic disorders (everything from your muscles spontaneously disintegrating when exercising to some forms of diabetes--at least one form of diabetes/"metabolic syndrome" HAS been linked to mtDNA hiccups and is colloquially known as "Type III Diabetes" by researchers)

b) Mitochondria, unlike every other part of a cell, have their own separate genetic code that is actually more related to bacteria than eukaryotic life (the latest theory is that mitochondria are basically descendants of rickettsia that may have colonised ur-eukaryotic cells and then set up such a strongly symbiotic relationship that one can't live without the other...the really interesting thing is that this happened at least twice, with bikonts (including plants) having the same thing going on with chloroplasts (descended from cyanobacteria) and unikonts with mitochondria (likely rickettsia-descendents)...seriously, it's enormously neat if you think of it, right up there with endogenous retroviruses being a possible kick-start for evolution neatness).

In other words, this is more akin to a functional organ transplant--basically a "cell organ" is broken, so they put the nucleus of a cell in a denucleated egg with working "cell organs" (which are actually bacteria!)...

Not nearly as squidgy IMHO as, say, surrogate parenting proper :D
 
2012-06-12 05:52:38 PM
Somacandra: ph0rk: f you have bad DNA, why the fark do you need to procreate anyway?

Protip: No one ever turns and says to the spouse: "Let us create babby for to spread great DNA"


Why are you channeling meow_said?
 
2012-06-12 05:53:01 PM
Listen to the liberal parents whine when their precious little snowflakes are failing in the real world because they chose to go with their natural, new agey conception and incubation. You had plenty of opportunity to give your child the tools they'd need to succeed in life, but you chose not to have a superhuman. Too bad, so sad.

/I feel like I'd understand this process better through a hilariously over-simplified cartoon.
 
2012-06-12 05:59:47 PM
ph0rk: No, but by the time you're seeing your nth specialist and looking for a second woman to donate an egg, you've probably been informed that one of you has pretty shiatty DNA.

Not really. Fertility problems sometimes have very little to do with the "quality" of someone's DNA. For example, a variety of environmental factors can cause men to create "monstrous sperm" or teratozoospermia. Over 85% of these sperm in a sample and that's considered infertile.
 
2012-06-12 06:01:25 PM
It's a lot easier to know which side of the family to blame when there's only two donors (and of course the kid didn't get that from MY side of the family!) when the kid starts displaying bad habits.
Having to figure which to blame, between two other donors makes this needlessly complicated.
 
2012-06-12 06:02:07 PM
demaL-demaL-yeH: Why are you channeling meow_said?

Because saying "Let us create babby for to spread great DNA" is hilarious, especially in an overserious deep voice.

I actually find the aforementioned poster quite hilarious as well :-)

LAUGHTEROL
 
2012-06-12 06:03:29 PM
FloydA: CrispFlows:

Isn't what's wrong with eugenics the concept of racial purity? THAT's the ethical flaw, not the 'controlled breeding' .

Historically, that's what caused it to lose favor among the general public. It had already fallen out of favor among biologists about 20 years earlier, because it is abject nonsense.


It fell out of favor because Hitler.
The basic tenants of the practice require you to treat people like dogs but would probably work. The idea is Something Europeans never had a problem with. Then one of their leaders got serious about it.

The Germans wanted to be a superior people up until Hitler showed them, and everyone else, what it takes to make the sausage.
It's social madness that was considered acceptable for a long time. He made it unfashionable.

/He also ruined a mustache.
 
2012-06-12 06:05:07 PM
dericwater: redonkulon: Just take the mitochondria from the father who presumably isn't a waster and mix it with the broken ones from the mother. The healthier mitochondirons will win out and then the merger is just from 2 parents and the ethicists can go back to lighting up their bongs.

I believe the mitochondria comes only from the mother. Maybe my cell biology information is wrong.


They are just from the mother--sperm, alone of all cells other than mature erythrocytes, lack mitochondria (or pretty much anything else other than DNA and a way to get the DNA into the egg)...much as erythocytes lack nuclei, mitochondria, or really anything other than ways to carry hemoglobin.

Eggs do have mitochondria, hence why we can quite reliably say that mitochondria (and hiccups in mtDNA) are from Mom's side of the family.

The particular process that's being used involves taking a nucleus (which contains the actual genetic code) from a cell that has broken mitochondria, and placing it in a denucleated (and unfertilised) egg that has working mitochondria--the only way it'd ever work with daddy's DNA is if you managed to rejuvenate adult cells into stem cells, split this, and somehow make an egg out of the "X" half.
 
2012-06-12 06:06:46 PM
t0.gstatic.com
Doctor, you mentioned the ratio of ten women to each man. Now, wouldn't that necessitate the abandonment of the so-called monogamous sexual relationship, I mean, as far as men were concerned?
jenniferlynn612.files.wordpress.com

Regrettably, yes. But it is, you know, a sacrifice required for the future of the human race. I hasten to add that since each man will be required to do prodigious... service along these lines, the women will have to be selected for their sexual characteristics which will have to be of a highly stimulating nature.


Ambassador de Sadesky: I must confess, you have an astonishingly good idea there, Doctor.
 
2012-06-12 06:18:14 PM
way south: FloydA: CrispFlows:

Isn't what's wrong with eugenics the concept of racial purity? THAT's the ethical flaw, not the 'controlled breeding' .

Historically, that's what caused it to lose favor among the general public. It had already fallen out of favor among biologists about 20 years earlier, because it is abject nonsense.

It fell out of favor because Hitler.



That's correct.


The basic tenants of the practice require you to treat people like dogs but would probably work.


That is not correct. It's based on an assumption that (A) a "superior" phenotype can be objectively identified, (B) that the selective environment is stable, and (C) that removing unwanted variation will have no maladaptive repercussions.

None of those assumptions stands up to scrutiny.


So you're correct that it became "unfashionable" due to the revelations of the Nazi atrocities, but it was already largely abandoned by scientists a couple of decades before the rise of the Nazis.
 
2012-06-12 06:18:56 PM
serpent_sky: serial_crusher: I object to fertility science in general.
If you have some biological fault that prevents you from producing healthy children, just go adopt some of the perfectly fine ones

There are some pretty rough adoption stories out there and a lot of adopted kids don't end up so well off, what with having to come to terms with biological parent(s) that didn't want them, often not knowing much, if anything, about their genetic background.,things like that. Plus, not everyone could love an adopted child like their own.

There's also EXTREMELY high standards for adoption, to the point that a good lot of people don't qualify, but anyone can go for fertility treatments as far as I know.

I know I would be a horrible parent (I don't like kids) and wouldn't be good at either. I resent people telling me how much I should want kids, so I'll extend the same courtesies I'd like extended to me to people desperate enough to have children that they spend tons of money and go through many emotionally difficult and medically invasive procedures to have them. And I certainly respect people who can, and do, adopt.


Pretty much this. The adoption specs are so hard to get through that even good, loving foster parents who've had the kid for 10 years and the kid wants to stay with them, can't get adoption rights half the time.

Plus, even with a legal adoption that (supposedly) severs all parental rights, you have to worry about a biological parent out there somewhere deciding she was pressured into adoption, or is REALLY ALL BETTER NOW and would be a great mom, or something similar. Not saying that it happens all the time, or even very often, but it's got to be on the minds of everyone who adopts a kid.

I'm not sure why we as a society make it really easy for dumbasses to have kids and so hard for decent people to pick up after them when the kids need parents.
 
2012-06-12 06:29:03 PM
LeroyBourne:

I don't know what's stranger, the fact that HumbertoEcho was keeping tabs on her/their birthday or what it would be like to get a beej like that. One thing is for sure is that I'd have scrunchies on hand to tie up their hair. I'd want to see what's going on.

How long have you been on Fark? :-)

Somebody has to be the first to tap that. For science.
 
2012-06-12 06:36:48 PM
serial_crusher: I object to fertility science in general.
If you have some biological fault that prevents you from producing healthy children, just go adopt some of the perfectly fine ones that need homes. Yes, even the black ones.



You'd change your mind if you were diagnosed with the fault yourself, believe me.
 
2012-06-12 06:37:57 PM
lazyguineapig33: ph0rk: Mostly makes sense to me, with one minor question:

If you have bad DNA, why the fark do you need to procreate anyway? No shortage of humans, people.

in this case they were replacing the mitocondria. mitocondria are actually highly highly evolved symbiotic organisms. they have their own DNA and reproduce on their own inside your cells. What they did here is more like a transplant than replacing genes.


Charles Wallace?

/obscure?
//paging Dr. Colubra
 
2012-06-12 06:45:08 PM
HumbertoEcho: [www.eatnineghost.com image 450x341]

You guys are slipping. They are legal since a few years already.... :-)


It is pretty impressive that they are now I think 22 and they haven't done any major media that I am aware of since they were like 16 or 17.

Although, I found their uncyclopedia page, and it is pretty funny... http://uncyclopedia.wikia.com/wiki/Brittany_Hensel
 
2012-06-12 06:46:03 PM
Podmore makes a valid point that should be stressed:

A lot of people don't get that, for lots of women, part of their self worth is wrapped up in being able to make a baby. It's not rational, but it's true. Probably like a guy being able to get an erection

i wondered why couples with known serious genetic defects in their families are still bound & determined to have their own. evidently the pull is so strong that nature & wishful thinking wins out. evidently the ticking clock is strong mojo.

Mrs.Kritter has a slew of sisters each with a slew of children while she could have none. Yes it is apparent the presence or absence of children affects peoples lives.
 
2012-06-12 06:47:00 PM
FloydA: Somacandra: ph0rk: f you have bad DNA, why the fark do you need to procreate anyway?

Protip: No one ever turns and says to the spouse: "Let us create babby for to spread great DNA"


If I was married and wanted kids, I definitely would say it exactly that way!


Lady Oreamnos says this regularly. Based on observation, I say no matter what the genetic input, that stupidity, uh... finds a way.

/breeding also appears to cause brain damage in the parents
 
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