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(Yahoo)   News: Doctors discover that a drug that will reduce your chances of dying from most common forms of cancer by up to 60% when taken daily. Holy fark: It's aspirin   (news.yahoo.com) divider line 70
    More: Interesting, aspirin, lung cancer, prostate cancer, esophageal cancer, The Lancet, infant formula, NYU Langone Medical Center, cardiovascular diseases  
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3678 clicks; posted to Geek » on 07 Dec 2010 at 12:08 PM (3 years ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



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2010-12-07 11:44:19 AM
looks like aspirin is next up on the Schedule I list...
 
2010-12-07 12:00:47 PM
In other news, Merck has just sequenced the DNA of the willow tree and applied for a patent on any and all products derived therefrom
 
2010-12-07 12:11:34 PM
Tomorrow's headline: Study shows aspirin increases your cancer risk by 60%.
 
2010-12-07 12:19:05 PM
This totally explains why married men tend to live longer.
 
2010-12-07 12:19:30 PM
Weaver95: looks like aspirin is next up on the Schedule I list...

That's what I'm assuming.
 
2010-12-07 12:22:47 PM
Saw a news story about this yesterday. I haven't read the report, but if someone has, or has more info about it: have they ruled out the correlation/causation factor? Perhaps someone who takes aspirin daily is more inclined to take better care of themselves overall?
 
2010-12-07 12:23:14 PM
I've read (not remembering where) that many cancers have been correlated to chronic low-level general inflammation. Likely an aspirin regiment impacts that factoring. If this is the case the same could be addressed comparably through healthier diets and exercise. Pursuing pill solutions is much more American though.
 
2010-12-07 12:29:15 PM
This scientific break thru brought to you by the good people at Bayer.

ecx.images-amazon.com

/Bayers repeating
 
2010-12-07 12:29:15 PM
Weaver95: looks like aspirin is next up on the Schedule I list...

Why do you think that?
 
2010-12-07 12:29:29 PM
Nexzus: Saw a news story about this yesterday. I haven't read the report, but if someone has, or has more info about it: have they ruled out the correlation/causation factor? Perhaps someone who takes aspirin daily is more inclined to take better care of themselves overall?

Or other factors, like people who take aspirin are much less likely to regularly take acetaminophen or ibuprofen, maybe they have some relation to it?

Or that a huge group of people who take aspirin are those typically cannot take either of the aforementioned painkillers (due to a history of clotting or interactions or whatnot).
 
2010-12-07 12:30:33 PM
Treygreen13: Tomorrow's headline: Study shows aspirin increases your cancer erectile dysfunction risk by 60%.

FTFY
 
2010-12-07 12:32:06 PM
Yeah, pretty much what Nexzus said. Even if the doctors said 'Group A take aspirin daily, group B don't,' I'm sure not everyone in group A took aspirin every day. Did they throw out the ones that didn't? Goes back to the whole if they are going to take aspirin every day for 20 years they are more likely to exercise regularly and eat better as well.
 
2010-12-07 12:34:15 PM
BlazeTrailer: I've read (not remembering where) that many cancers have been correlated to chronic low-level general inflammation. Likely an aspirin regiment impacts that factoring. If this is the case the same could be addressed comparably through healthier diets and exercise. Pursuing pill solutions is much more American though.

Seems to coincide with another of their findings:

"And while cautioning that more research is necessary to build on this "proof of principle," the authors suggested that people who embark on a long-term, low-dose aspirin regimen in their late 40s and 50s are probably the ones who stand to benefit the most."

Late 40s/50s being people that have probably stopped working out and possibly eating right. Though it appears to provide a slight benefit for the younger test subjects. I'm guessing it is more beneficial for people that don't eat right and work out then people who do, but that wouldn't necessarily mean it wont help those working out a little bit.
 
2010-12-07 12:35:04 PM
cast55: This totally explains why married men tend to live longer.

Aspirin also causes partial deafness in married males.

/Tip your waitresses
 
2010-12-07 12:42:50 PM
Weaver95: looks like aspirin is next up on the Schedule I list...

Cannabis and Aspirin should be at the same level, regardless of if it's Schedule I or not scheduled at all. What with the pharmacopoeia of Western medicine (pre-1937) entry and all.

Thanks a lot Marihuana Tax Act of 1937.
 
2010-12-07 12:43:28 PM
Is there nothing astin can't do?
 
2010-12-07 12:43:46 PM
BlazeTrailer: I've read (not remembering where) that many cancers have been correlated to chronic low-level general inflammation. Likely an aspirin regiment impacts that factoring. If this is the case the same could be addressed comparably through healthier diets and exercise. Pursuing pill solutions is much more American though.

It goes back to Virchow in the 1860s - he was the first to connect chronic inflammation with cancer. There are a host of reasons for the connection: immune cells release reactive oxygen species to destroy invaders but can also damage DNA in cells, immune response generates a whole bunch of molecular signals that act as pro-growth signals in cancer cells, etc.

if anyone's interested in the technical stuff: Link (new window)

/molecular biologist studying cancer and inflammation
 
2010-12-07 12:44:04 PM
You know what else will reduce death by cancer? A bullet in the head.
 
2010-12-07 12:47:38 PM
still no cure for cancer

/bringing it back
 
2010-12-07 12:52:20 PM
bad_blood: It goes back to Virchow in the 1860s - he was the first to connect chronic inflammation with cancer. There are a host of reasons for the connection: immune cells release reactive oxygen species to destroy invaders but can also damage DNA in cells, immune response generates a whole bunch of molecular signals that act as pro-growth signals in cancer cells, etc.

So why the hate for aspirin? Is It a money thing?
 
2010-12-07 12:53:36 PM
Actually for those of us interested in the science behing low-carb diets, this finding isn't too suprising. It's well known that aspiring generally works its magic by blocking micro hormones in the body called eicosaniods, of which there are two series, production of one is triggered by insulin, the other by glucagon. The Insulin series Eicos tend to contstrict airways and bloodvessels, speed blood clotting, and encourage rapid cellular proliferation which can be linked to cancer. The Glucagon ons do the opposite. Since the average American diet is such that most people produce more insulin that glucagon, the eicos most likely to be present, and therefore blocked, by aspirin are the Insulin series which includes the eicos linked to tumor and cancer growth
 
2010-12-07 12:59:35 PM
bad_blood: BlazeTrailer: I've read (not remembering where) that many cancers have been correlated to chronic low-level general inflammation. Likely an aspirin regiment impacts that factoring. If this is the case the same could be addressed comparably through healthier diets and exercise. Pursuing pill solutions is much more American though.

It goes back to Virchow in the 1860s - he was the first to connect chronic inflammation with cancer. There are a host of reasons for the connection: immune cells release reactive oxygen species to destroy invaders but can also damage DNA in cells, immune response generates a whole bunch of molecular signals that act as pro-growth signals in cancer cells, etc.

if anyone's interested in the technical stuff: Link (new window)

/molecular biologist studying cancer and inflammation


That's interesting. So why would anyone expect aspirin to have greater effect than any drug with anti-inflammatory properties?

And I stand by my diet/exercise comment. I know some types of foods are tied to such inflammation more than other types. I don't remember the theorized physiology behind the exercise piece though.
 
2010-12-07 01:00:15 PM
GutFunk: Yeah, pretty much what Nexzus said. Even if the doctors said 'Group A take aspirin daily, group B don't,' I'm sure not everyone in group A took aspirin every day. Did they throw out the ones that didn't? Goes back to the whole if they are going to take aspirin every day for 20 years they are more likely to exercise regularly and eat better as well.

According to the article it was a 5 year study, and they were provided with low doses of Aspirin to take daily (75mg). This isn't a case of let's look at a bunch of people and figure out what they have in common.
 
2010-12-07 01:01:58 PM
Yes, take aspirin everyday. Just never cut yourself, becaue you'll bleed and bleed and bleed.
 
2010-12-07 01:02:25 PM
Holy shiat. What doesn't asprine fix? Lets sprinkle some on the Federal deficit and see what happens.
 
2010-12-07 01:03:16 PM
Aren't most middle-age people already taking low-dose aspirin for cardiovascular health?

/81 mg
 
2010-12-07 01:05:09 PM
...and so the doctor says "Take two red pills every morning with a glass of water, take the yellow pill with a glass of water after lunch, and take three blue pills with a glass of water just before going to bed each night. Follow this regimen for 3 weeks" The patient asks "That's an awful lot of pills; what seems to be the problem?"

Doctor replies, "You're not drinking enough water".
 
2010-12-07 01:07:17 PM
Nexzus: Saw a news story about this yesterday. I haven't read the report, but if someone has, or has more info about it: have they ruled out the correlation/causation factor? Perhaps someone who takes aspirin daily is more inclined to take better care of themselves overall?

All the people that I know that take aspirin daily were told to do so by their doctor because of heart conditions(or heart attacks).
 
2010-12-07 01:11:23 PM
Magorn: In other news, Merck has just sequenced the DNA of the willow tree and applied for a patent on any and all products derived therefrom

Gotta love those salicylates.
 
2010-12-07 01:20:03 PM
reddawg555: Holy shiat. What doesn't asprine fix?

Haemophilia
 
2010-12-07 01:22:27 PM
mcreadyblue:, BlazeTrailer:

It's not that there's hate for aspirin, just that all medical boards and groups are super careful about just saying "hey, take anti inflammatories forever". Look what happened with people taking Cox-2 inhibitors chronically (CV risk). And if you want a look at what happens when they do deliberate and carefully release new guidelines, check out the news twisting the new mammogram schedules earlier this year - they basically made it sound like the NIH wanted women to die. They're sort of in a no win scenario when it comes to consumers and not talking directly to physicians.

Magorn: Actually for those of us interested in the science behing low-carb diets, this finding isn't too suprising. It's well known that aspiring generally works its magic by blocking micro hormones in the body called eicosaniods, of which there are two series, production of one is triggered by insulin, the other by glucagon. The Insulin series Eicos tend to contstrict airways and bloodvessels, speed blood clotting, and encourage rapid cellular proliferation which can be linked to cancer. The Glucagon ons do the opposite. Since the average American diet is such that most people produce more insulin that glucagon, the eicos most likely to be present, and therefore blocked, by aspirin are the Insulin series which includes the eicos linked to tumor and cancer growth

If you want to get more molecular biology-y, the whole prostaglandin metabolism pathway is rife with transient by products that induce inflammation (i.e, PGE2)
 
2010-12-07 01:35:53 PM
I went to the 100 Anniversary of aspirin party thrown by Bayer at the German embassy about 10 years ago. Good party! Lots of free booze. I probably took tylenol fo the hangover the next day though.
 
2010-12-07 01:48:29 PM
Makes sense. The reason you take it to ward off heart attacks is because inflammation makes plaque in your blood vessels unstable & squishy, making it much more likely to burst & cause the blood clot that blocks the artery & kills you.
 
2010-12-07 02:06:11 PM
happydude45: Makes sense. The reason you take it to ward off heart attacks is because inflammation makes plaque in your blood vessels unstable & squishy, making it much more likely to burst & cause the blood clot that blocks the artery & kills you.

Actually, the reason it's given for heart disease patients is that it causes an irreversible anti-thrombotic effect by farking up platelets' COX-1 enzyme.
 
2010-12-07 02:10:01 PM
Bleh I'm allergic to aspirin so I'm pretty screwed
 
2010-12-07 02:15:11 PM
CSB... took tylenol fo the hangover... /CSB

PSA: do NOT take tylenol (acetaminophen) with alcohol. Seriously, it shreds your liver.

If they'd discovered it this year it would be prescription-only.
 
2010-12-07 02:16:20 PM
Oh, and don't try to kill yourself with Tylenol either - it takes you about 3 days to die painfully of liver failure; way too long to have second thoughts...
 
2010-12-07 02:20:39 PM
and in 30 years, EVERY drug ever produced by a drug company in this Nation will have miraculous properties.


hell, those liars will have convinced americans by then that viagra will make them smart.


fools will be fools......


wanna' know what reduces cancer the most??

1)eat whole natural foods...avoid processed crap and artificial colors/flavors,preservatives, etc etc.

2)exercise

3)get enough sleep

4)minimize stress

5)avoid drugs and bad habits like boozing, nicotine, etc

6)keep at a healthy weight

7)have healthy/satisfying personal relationships and community life

8)ta da!! its MAGIC!

there you have it. simple. but no drug pusher is going to tell you that because he won't be able to sell you more drugs.
 
2010-12-07 02:25:29 PM
Linux_Yes:
wanna' know what reduces cancer the most??


1. Be born with superior genetics.

/game over
 
2010-12-07 02:26:13 PM
Linux_Yes: and in 30 years, EVERY drug ever produced by a drug company in this Nation will have miraculous properties.


hell, those liars will have convinced americans by then that viagra will make them smart.


fools will be fools......


wanna' know what reduces cancer the most??

1)eat whole natural foods...avoid processed crap and artificial colors/flavors,preservatives, etc etc.

2)exercise

3)get enough sleep

4)minimize stress

5)avoid drugs and bad habits like boozing, nicotine, etc

6)keep at a healthy weight

7)have healthy/satisfying personal relationships and community life

8)ta da!! its MAGIC!

there you have it. simple. but no drug pusher is going to tell you that because he won't be able to sell you more drugs.


You forgot a few: "inherit good genes" "no smoking" and "don't work around known carcinogens." I see you included nicotine but it's not the nicotine in tobacco that kills, it's the known cancer causing agents in the inhaled smoke.
 
2010-12-07 02:30:02 PM
Precious Roy's Horse Dividers: Is there nothing astin can't do?

Boil em, mash em, stick em in a stew...
 
2010-12-07 02:43:40 PM
Linux_Yes: and in 30 years, EVERY drug ever produced by a drug company in this Nation will have miraculous properties.


hell, those liars will have convinced americans by then that viagra will make them smart.


fools will be fools......


wanna' know what reduces cancer the most??

1)eat whole natural foods...avoid processed crap and artificial colors/flavors,preservatives, etc etc.

2)exercise

3)get enough sleep

4)minimize stress

5)avoid drugs and bad habits like boozing, nicotine, etc

6)keep at a healthy weight

7)have healthy/satisfying personal relationships and community life

8)ta da!! its MAGIC!

there you have it. simple. but no drug pusher is going to tell you that because he won't be able to sell you more drugs.


Then explain to me why cancer was rampant in ancient Egypt. They ate tons of totally organic foods heavy on the whole grains and light on the red meat, got plenty of exercise, nary a one of them smoked, most slept from sundown to sun-up, and they liked to do things as a community, like bang out pyramids
 
2010-12-07 02:45:11 PM
Magorn: Linux_Yes: and in 30 years, EVERY drug ever produced by a drug company in this Nation will have miraculous properties.


hell, those liars will have convinced americans by then that viagra will make them smart.


fools will be fools......


wanna' know what reduces cancer the most??

1)eat whole natural foods...avoid processed crap and artificial colors/flavors,preservatives, etc etc.

2)exercise

3)get enough sleep

4)minimize stress

5)avoid drugs and bad habits like boozing, nicotine, etc

6)keep at a healthy weight

7)have healthy/satisfying personal relationships and community life

8)ta da!! its MAGIC!

there you have it. simple. but no drug pusher is going to tell you that because he won't be able to sell you more drugs.

Then explain to me why cancer was rampant in ancient Egypt. They ate tons of totally organic foods heavy on the whole grains and light on the red meat, got plenty of exercise, nary a one of them smoked, most slept from sundown to sun-up, and they liked to do things as a community, like bang out pyramids


Not to mention didn't live past 40-50 very often.
 
2010-12-07 02:53:56 PM
Nexzus: Saw a news story about this yesterday. I haven't read the report, but if someone has, or has more info about it: have they ruled out the correlation/causation factor? Perhaps someone who takes aspirin daily is more inclined to take better care of themselves overall?

or that chronic aspirin takers die of liver disease before cancer ever has a chance to take hold?
 
2010-12-07 02:55:27 PM
Magorn: Linux_Yes: and in 30 years, EVERY drug ever produced by a drug company in this Nation will have miraculous properties.


hell, those liars will have convinced americans by then that viagra will make them smart.


fools will be fools......


wanna' know what reduces cancer the most??

1)eat whole natural foods...avoid processed crap and artificial colors/flavors,preservatives, etc etc.

2)exercise

3)get enough sleep

4)minimize stress

5)avoid drugs and bad habits like boozing, nicotine, etc

6)keep at a healthy weight

7)have healthy/satisfying personal relationships and community life

8)ta da!! its MAGIC!

there you have it. simple. but no drug pusher is going to tell you that because he won't be able to sell you more drugs.

Then explain to me why cancer was rampant in ancient Egypt. They ate tons of totally organic foods heavy on the whole grains and light on the red meat, got plenty of exercise, nary a one of them smoked, most slept from sundown to sun-up, and they liked to do things as a community, like bang out pyramids


What makes you think diets that are heavy in whole grains are healthy?
 
2010-12-07 03:13:22 PM
Linux_Yes: and in 30 years, EVERY drug ever produced by a drug company in this Nation will have miraculous properties.


hell, those liars will have convinced americans by then that viagra will make them smart.


fools will be fools......


wanna' know what reduces cancer the most??

1)eat whole natural foods...avoid processed crap and artificial colors/flavors,preservatives, etc etc.

2)exercise

3)get enough sleep

4)minimize stress

5)avoid drugs and bad habits like boozing, nicotine, etc

6)keep at a healthy weight

7)have healthy/satisfying personal relationships and community life

8)ta da!! its MAGIC!

there you have it. simple. but no drug pusher is going to tell you that because he won't be able to sell you more drugs.


I'd rather listen to a "drug pusher" than a fool.
 
2010-12-07 03:19:30 PM
cast55: This totally explains why married men tend to live longer.

LOL...oh man.. just took a swig of Coca-Cola.. it burns coming out the nostrils.
 
2010-12-07 03:23:55 PM
Magorn: Then explain to me why cancer was rampant in ancient Egypt.

Jesus hadn't come yet.
 
2010-12-07 03:48:33 PM
Magorn: Then explain to me why cancer was rampant in ancient Egypt.

The nerve gas that God sent to kill all the first-born turned out to be a mutagen in the adult population.
 
2010-12-07 04:08:45 PM
BlazeTrailer: If this is the case the same could be addressed comparably through healthier diets and exercise.

I take aspirin prior to exercise to reduce muscle soreness.

My diet, however, remains sub-optimal; it consists primarily of "junk foods" and dietary supplements.
 
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