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(Yahoo)   Scientists discover genetic "On/Off" switch for chronic pain. Still no cure for cancer, but arthritis is getting nervous   ( news.yahoo.com) divider line
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12965 clicks; posted to Main » on 30 Jul 2006 at 12:01 PM (11 years ago)   |   Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



103 Comments     (+0 »)
 


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2006-07-30 11:06:19 AM  
I love the "still no cure for cancer" cliche. As if anyone's looking for cures anymore. Why cure a patient with one expensive pill, when instead you can "treat" them with one expensive pill a day for the rest of the patient's life. Extracting a continuous stream of money is the goal. Capitalist medicine looks for "treatments", not cures.
 
2006-07-30 12:05:14 PM  
YES!!!

As a man in his early 40s who is already crippled by osteoarthritis this really makes me happy in my joints....

.... as long as side effects don't include heart attacks, thank you very much Vioxx.
 
2006-07-30 12:06:15 PM  
Stiletto, you took all the fun out of it.

/Still, you're right.
 
2006-07-30 12:08:15 PM  
Scientific research is the work of the devil!
 
2006-07-30 12:09:20 PM  
Same reason why they won't a toothpaste that repairs cavities,stiletto_the_wise.

As long as these things are vetoed or approved by a board 100% affected by the industry, things that cripple them like instant cures will always be pushed under the rug.
 
2006-07-30 12:09:55 PM  
won't make
 
2006-07-30 12:10:31 PM  
Leprosy?
 
2006-07-30 12:10:53 PM  
Capitalist medicine looks for "treatments", not cures.

So you mean my doctor lied to me when I moved from remission to being cured of cancer? That bastard just wants a continuous stream of money! That's exactly why he said I only need to go every year (or less) depending on how I feel and should only get an X-ray annually instead of a CT-scan. BASTARD!!!
 
2006-07-30 12:11:22 PM  
I wonder if this might be an eventual treatment for fibromyalgia, as well.
 
2006-07-30 12:11:36 PM  
Ask Dre about the cure for chronic pain...

/'mo chronic, fool
 
2006-07-30 12:11:57 PM  
I'm in!

/chronic pain sufferer
//seriously
 
2006-07-30 12:12:17 PM  
If God had wanted us to be pain free, he wouldn't have given us this protein.
 
2006-07-30 12:12:40 PM  
Stiletto, were you immunized against the many childhood diseases that were such a huge problem just a generation ago? Like polio, measles, whooping cough, diptheria, tetanus, mumps, etc.

Just wondering...
 
2006-07-30 12:12:43 PM  
stiletto_the_wise: Capitalist medicine looks for "treatments", not cures.

Sounds like you could use some yourself.
 
2006-07-30 12:13:12 PM  
To get the pain gene to switch off, does it involve applying something directly to forehead ?
 
2006-07-30 12:14:21 PM  
Man I wish they would turn mine off right now. I have the world worst case of Swimmers Ear EVER! Luckily my dad still has some hydrocodone left over from his surgery a couple months back. But man does it hurt like a .....


-Sean
 
2006-07-30 12:14:29 PM  
Stiletto

er... didn't they just "cure" (well, create a vaccine for)cervical cancer?
 
2006-07-30 12:14:34 PM  
tonesskin: That bastard just wants a continuous stream of money!


I think that was more pointed at pharmaceutical corporations and such. Not individual doctors, they have a little more incentive to keep you alive: reputation.
 
2006-07-30 12:14:46 PM  
this actually makes sense. my family on my mothers side, we deal with chronic pain all the time. my mother has osteoarthritis, sciatica, teeth issues, and fibromyalgia. she should be crippled with pain, but its just every so often it all flares up enough to be an issue. i have damaged joints that should hurt like a biatch that dont, a tooth thats needed root canal for a while, that the dentist poled six months ago, and i said, ow, that hurt a bit. the dentists responce? a bit? that should be hurting you 24/7.
 
2006-07-30 12:15:34 PM  
You'd apply it directly to your genes. Duh.
 
2006-07-30 12:16:48 PM  
I would have to say thanks to someone if this was true...!

I've forgotten what it's like to live a day without pain.

You learn to manage.
 
2006-07-30 12:16:53 PM  
AstroMech

Oh, in that case. Those damn pharmaceutical companies who designed my chemotherapy clearly want a steady stream of money. That is why they tell my doctor to lie to me and say I'm "cured" of cancer. And we all know that pharmaceutical companies could care less about reputation.

Bastard pharmaceutical companies and their cancer curing chemotherapy that is all a conspiracy to keep a steady stream of money coming their way! BASTARDS!!!!!!
 
2006-07-30 12:18:12 PM  
stiletto_the_wise: I love the "still no cure for cancer" cliche. As if anyone's looking for cures anymore. Why cure a patient with one expensive pill, when instead you can "treat" them with one expensive pill a day for the rest of the patient's life.

Yawn, another conspiracy theory. In actuality there are a plethora of companies working on various treatments and research towards a cure (different types of cancer would require different types of drugs). BUT, the person/team/company that finds and patents a CURE is going to make a farking buttload of money! Exponentially more then just a particular treating drug(s) for a particular type of cancer(s).

You're suggestion relies on the notion that captialists don't like to make farking buttloads of money.
 
2006-07-30 12:18:27 PM  
tonesskin: Bastard pharmaceutical companies and their cancer curing chemotherapy that is all a conspiracy to keep a steady stream of money coming their way! BASTARDS!!!!!!

There is no pleasing you. Would you be interested in the on/off switch that inspired this discussion?

/Bong and a blintz maybe?
 
2006-07-30 12:19:00 PM  
Ya know, there's a reason people feel pain. Without it, we'd all be indestructible... for just a moment anyway.
 
2006-07-30 12:20:36 PM  
Would you be interested in the on/off switch that inspired this discussion?

I guess that was my point in the first place. How did an on/off switch for pain inspire a discussion of OMG TEH CUMPNYS'LL NE'ER CURE DAPAIN!
 
2006-07-30 12:24:26 PM  
AstroMech

I think that was more pointed at pharmaceutical corporations and such. Not individual doctors, they have a little more incentive to keep you alive: reputation.


While I can understand where this sort of opinion is coming from, I hate to hear it. Have people become so cynical they can't believe in benevolent doctors anymore?
 
2006-07-30 12:24:26 PM  
What about the mental and financial pain caused by my ex-wife?
 
2006-07-30 12:24:56 PM  
tonesskin: I guess that was my point in the first place. How did an on/off switch for pain inspire a discussion of OMG TEH CUMPNYS'LL NE'ER CURE DAPAIN!

You need some topical cream for your argumentitis.

/Article was short but cool.
//My parents will be thrilled.
//I'm out.
 
2006-07-30 12:27:39 PM  
On/Off...apply directly to arthritis.
On/Off...apply directly to arthritis.
On/Off...apply directly to arthritis.
 
2006-07-30 12:28:18 PM  
stiletto_the_wise may be exaggerating a bit, but the ethical dilemma that corporate-sponsered research finds itself in is real. Remember, it's only been in the last couple of decades that most medical research has moved into the corporate domain.
 
2006-07-30 12:30:02 PM  
stiletto_the_wise

You're also mistaking pharmaceutical companies with peopling doing academic research. While money often comes from patents derived from scientific discoveries, you'd be hard pressed to find someone who is in the academic Biochemistry research field to make money... if that was their main goal, they'd have switched over to an industry job, where salaries double.
 
2006-07-30 12:34:20 PM  
My mother has had over 15 failed surgeries on her lower spine and surrounding areas (half of them to attempt to repair the damage already done by the previous surguries). This is the sort of thing that could potentially return some of her life to her. She will never have full mobility, but a nights sleep and the ability to walk from her room to the kitchen without a walker would be a nice a change. The reason we feel pain is to warn us when we are doing something harmful; in the case of my mother, and others with similar conditions, I do not think this is the case.

They (the doctors) refuse to do nerve separation on her as her pain affects too large of an area... instead they installed an internal morphine drop type thing... which effectively numbs the area AND makes go on the nod. This makes it hard for her to get through the day; and the machine needs to be replaced every 7 years, plus constant "refills" of whatever drug they put in it now. Nerve separation would have been a 30 minute mirco surgery that only ever needed to happen once. This is how the medical community chooses to deal with someone who has insurance... the most expensive procedures in the world, combined with the most expensive follow ups in the world.

After having conducted my own research into my mothers problem, I found the doctor was the wrong kind of doctor, and given her condition and the location of the slipped disk, he did the absolute WRONG procedjure. Mind you this is one of the top rated surgeons in the country, and he now refuses to return phone calls from me or my mother. Dr. Tom Jones (No joke) Neuro-surgery.... the guys a dick. I wanted to make sure that everyone who is in the greater Santa Barbara area knows about this guy. He might be good surgeon, but hes a terrible human being.

Also, as I did find that there were multiple other less invasive options for her condition, even at the time, and that there were FAR better recovery options then the gizmos and devices they were telling her she needed to buy; I am going to side with Stilleto on this one. The medical community is a business, and most of the people within that community seem to view the patients like a butcher views a cow.
 
2006-07-30 12:35:07 PM  
Sorry but, ahhh, no.

Pain happens for a reason. Those who don't experience pain tend to damage themselves, using their hands as hammers and pliers, they lop off ends of fingers and bite their tongues.

Does chronic pain happen without cause? My father has chronic pain in the spine, pelvic area, and legs. They've been misdiagnosing, performing useless operations to remove or reattach imaginary stuff, and bouncing him from doctor to doctor, specialist to specialist etc... for years and years.

I should add: These are hmo doctors. So if they don't which drug to throw at it then they give you vicodin and prozac and schedule another appointment in 6 months - hoping for addiction, divine intervention, or death. Anything other than those three things gets you more vicodin and prozac. No cutting edge medical breathroughs happening here.

I'll bet that genetic "on/off" switch (which could lead to a drop in vicodin and prozac sales) gets forgotten about anyway, even if it isn't snake oil.

Of course, from a Pollyanna perspective, one might appreciate being able to withstand pepper spray, mace, fire (for short periods), microwave weapons, and those damn "HEAD ON: APPLY DIRECTLY TO THE FORHEAD" commercials.
 
2006-07-30 12:36:21 PM  
I'm sure that if people could cure cancer, they would. People (especially Americans) still have tons of things wrong with them. If cancer is cured, they'll just move on to other problems. Also, people don't really appreciate how tough cancer is to kill. I mean, the cure for cancer is bleach. The only problem is, bleach tends to kill you along with the cancer.

/Have a lot of friends and colleagues working on cancer therapies. They dedicate their lives to trying to make cancer patients' lives better.
 
2006-07-30 12:37:05 PM  
I had horrible sciatica for six months, and then I read "The Mindbody Prescription" by Dr. John Sarno. The book alone pretty much fixed me. It totally goes against everything conventional medicine says about chronic pain, and I believe it, because it worked better for me than any medical advice I have ever received.
 
2006-07-30 12:37:35 PM  
Let me just mention that in ancient China, instead of paying doctors for treating them, they did the exact opposite: They paid a doctor a retainer fee on a regular basis, and then when they got sick they STOPPED paying him until he made them healthy again. There's incentive for ya, yes?
 
2006-07-30 12:40:30 PM  
So...If I like get this shot then......My Mother-in-Law will go away/?/
 
2006-07-30 12:40:36 PM  
[image from raw360.com too old to be available]
/Unimpressed
 
2006-07-30 12:42:01 PM  
Bah! I'm perfectly happy with Morphine thanks very much.
 
2006-07-30 12:43:38 PM  
So you mean my doctor lied to me when I moved from remission to being cured of cancer?

If it wasn't removed, yes.
 
2006-07-30 12:53:08 PM  
Am I the only one who RTFA? There are no medical doctors involved here... Richard Ambron, Ph.D., is a Professor in the Columbia Department of Neurobiology and Behavior. He discovered a pathway important in chronic pain. That's a good thing, even if no medical treatment ends up coming from the discovery. He does not work for an "evil drug corporation", nor is he an "HMO Doctor". End of Story.
 
2006-07-30 12:56:39 PM  
Damn everyone has beaten me to "And that switch is called Morphine"
 
2006-07-30 12:56:49 PM  
stiletto_the_wise: Capitalist medicine looks for "treatments", not cures.


Well, that's definitely true compared to Communist medicine.
For example, in Western medicine, when a patient has an STD we treat that one disease while allowing the patient to continue having sex and contracting other diseases. In contrast, China during its Cultural Revolution simply had all persons with STD's killed. Now that's a cure for ya.

 
2006-07-30 12:58:14 PM  
My wife was a nationally-competitive equestrian as a teenager, until she was thrown off her mount into a concrete wall, breaking her back. She was told she would never walk again; after many many months of surgery, treatment, and physical therapy, she proved them wrong. Needless to say, she is still in serious pain, every day, and will be for the rest of her life.

She is now an anesthesiologist, working on a chronic pain fellowship, and studying to be a clinical chronic pain physician at a world-renowned medical research institution. She is also one of the most compassionate people I've ever met, partially because she can empathize with suffering. Her own experiences are directly responsible for her career path.

Capitalism be damned, if she could find a true cure for pain, she'd be the first in line to use it, and then treat anyone else who came to her in the same agony that she has experienced.

/Blame the corporations, but be careful not to lump the front-line physicians in with the establishment.
//My wife is also the bravest person I have ever met.
///I don't care if I'm being sappy, it's absolutely true.
 
2006-07-30 12:59:43 PM  
What are you complaining about, Skippy?

At least one person has already applied the "HeadOn" cliche...much to my chagrin.

/dammit
//I'm not bitter
///I'll get over it...
////there...over it...yep, still over it...and still over it...
 
2006-07-30 01:01:13 PM  
According to Dr. Sarno, most chronic pain is actually caused by your brain to serve as a physical distraction from things your subconcious has deemed stressful. For some reason your subconcious believes that physical pain is better than psychological stress.

By understanding where this pain truly eminates from, your brain starts to realize that the pain is actually ridiculous, and begins to shut it off.

You have to actually stop doing all of the "rituals" you engage in on a daily basis to stop the pain, because all of these things serve as a distraction, and help aid the reason your brain started the pain in the first place.
 
2006-07-30 01:22:21 PM  
Ghastly
YES!!!
As a man in his early 40s who is already crippled by osteoarthritis this really makes me happy in my joints....
.... as long as side effects don't include heart attacks, thank you very much Vioxx.


A cure or even something that just stops the cycle of chronic pain would be life changing!
They tried me on Vioxx, I felt great on day three, just before the crippling chest pains set in.
 
2006-07-30 01:25:15 PM  
Boobies N' Beer. The cause of and solution to all of life's problems.

[image from img115.imageshack.us too old to be available]

/I lub you Elisha Cuthbert doppelganger
 
2006-07-30 01:25:37 PM  
[image from myspace-248.vo.llnwd.net too old to be available]

The doctor said I need a backiotomy!
 
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