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(Salt Lake Tribune)   Killer cocktail of compounds collected from cone snail creature creates comforting chemical for courageous cancer-battling congregate   (sciencentral.com) divider line 35
    More: Cool  
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3960 clicks; posted to Main » on 03 Apr 2005 at 4:43 AM (10 years ago)   |  Favorite    |   share:  Share on Twitter share via Email Share on Facebook   more»



35 Comments   (+0 »)
   

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2005-04-03 01:20:35 AM  
Still no cure...
 
2005-04-03 01:37:51 AM  
That is so cool, considering cone snails are some of the most poisonous creatures known. Poison + cancer = health?
 
2005-04-03 03:24:58 AM  
A good many current medicines are poisonous except in tiny doses.
 
2005-04-03 04:52:19 AM  
omg enough of this crap
 
2005-04-03 04:52:57 AM  
Ow, my head.

Alliteration gold to you, submitter.
 
2005-04-03 04:53:34 AM  
Close, submitter, but you could have replaced Killer with calamitous :P
 
2005-04-03 04:54:33 AM  
Escargot is expensive so I collected several dozen large snails from my German garden, kept them for weeks, washing, rinsing, feeding them flour until they were crapping pure white stuff. Prepared them according to a method gleaned from the internets. Results were less than satisfactory.
/is there a moral to this story? Nope.
[image from img226.exs.cx too old to be available]
 
2005-04-03 04:55:42 AM  
Clever Neologism

As I'm sure you know, most of what they use to treat cancer (chemo, radiation) is very poisonous to the body as well. I guess the idea is to hope that the rest of the body can stand up to (though sustain serious damage) what may actually kill or stop the growth of the mutated cells.

It's interesting logic.
 
2005-04-03 04:57:54 AM  
After reading TFA, there was no reference anywhere to cancer. Submitter didn't read the article either, I take it?
 
2005-04-03 04:58:12 AM  
If my neighbor is a pain in the butt, do I eat a cone snail myself or shove it up his ass?
 
2005-04-03 05:04:37 AM  
Zyklon B. Goode:

I think the moral is that snails taste as good as they look.
 
2005-04-03 05:06:49 AM  
Zyklon B. Goode:

I think I see Akbar in that pic!
 
2005-04-03 05:10:13 AM  
"...we never dreamt when we started that it would lead to a therapeutic application."

WELL, WHY IN GOD'S NAME ARE THEY STUDYING THE GD SNAILS FOR!!!!...?

Stupid scientists just picking crap up from anywhere, blindly going along putting HCL on anything to melt it and then say "Let's see if this will kill germs!!!"
"Did it work?"
"No."
"Add salt."
 
2005-04-03 05:14:12 AM  
Pot comes from snails?
 
2005-04-03 05:16:15 AM  
Anyone watch Penn & Teller's Bull@#$% ?

This is totally giving me the image of the snail mucus facials.
 
2005-04-03 05:28:14 AM  
Sorry, you're trying way too hard.
 
2005-04-03 05:42:34 AM  
ahbtbone: WELL, WHY IN GOD'S NAME ARE THEY STUDYING THE GD SNAILS FOR!!!!...?

In other news, still no cure for cancer.
 
2005-04-03 06:44:57 AM  
"Morphine is the gold stallion for any analgesics," says Dubois.

WTF's a 'gold stallion'?
 
2005-04-03 09:00:01 AM  
""Morphine is the gold stallion for any analgesics," says Dubois."
I think he means 'the gold standard'
 
2005-04-03 09:10:05 AM  
WELL, WHY IN GOD'S NAME ARE THEY STUDYING THE GD SNAILS FOR!!!!...?

... Because that's what scientists DO. They study things; all things.

Gah! It's just so hard to keep my cool after seeing something like that. I am way more angry at anyone who thinks like that than they are angry at the scientists.

...

Want to know why they were studying the snails? THEY WERE STUDYING THE DAMN SNAILS BECAUSE IF THEY DIDN'T STUDY THE DAMN SNAILS, THEY'D HAVE NEVER FOUND OUT THAT THEIR VENOM CAN BE USED AS A PAINKILLER!

What the hell do you people think science is about? What, you think there's just some magic button labeled "Cancer Cure", and we just don't have enough Vespian Gas to research it!?

Scientists study and observe everything. Usually, they discover jack squat. Once in a while, they'll find something new. Once that new thing has been discovered, it can be researched, developed, and improved. However, when it comes to discovering anything new, focused scientific research almost never delivers.

Almost all major breakthroughs were accidental, or happened during unrelated research. The guy that discovered Penicillin wasn't testing the effect of mold on bacteria; he left a test sample out when he went on a trip, and when he came back, it was moldy.

You want to know what science is? Science is throwing spoiled milk out of a third story window onto a tin plate, just to see what sound it makes.

Here we are, a perfect example of just how this process works, and people are still biatching!...

I swear (and I say this too often), if society worked the way people like that are demanding, we would still be sitting in a cave, trying to find a "cure" for a "Fatal Tiger Mauling".
 
2005-04-03 09:28:47 AM  
Ooooooo. What a pretty snail.

/must. fight urge. to. pick up. pretty. snail.
 
2005-04-03 09:58:32 AM  
Charming cocktail contains compounds collected from cone-snail creature creates comforting chemical for courageous cancer crushing congregate
 
2005-04-03 10:51:13 AM  
C-I-L-L my land-lord.
 
2005-04-03 10:53:15 AM  
I had escargot in China, and it was delicioius.

Except the Chinese don't cut off the foot, which has granules of sand in it.

.
 
2005-04-03 11:00:08 AM  
Alliterative headlines suck.
 
2005-04-03 11:01:51 AM  
After all the radiation I got for my cancer I think cone snail poison would be a refreshing change. Especially if it's served with salt around the rim of the glass and a dash of lime.
 
2005-04-03 12:01:42 PM  
Came to congratulate and credit competent creator of cool headline copy consonance confection.
 
2005-04-03 01:36:06 PM  
I hate to get into semantics, but couldn't it be cone-snail?
 
2005-04-03 01:56:37 PM  
I don't care if 50,000,000 people could be helped, leave those snails alone.

Oops! I channeled some animal rights wacko, sorry.
 
2005-04-03 07:53:56 PM  
Just don't show this to the Republicans, who say progress is worth making extinct a few species here and there.
 
2005-04-03 10:03:59 PM  
Don't they mean whelks? What the f-ck is a cone snail?
 
2005-04-03 10:24:30 PM  
red_beard_neo

Just don't show this to the Republicans, who say progress is worth making extinct a few species here and there.


They won't actually have to use the snails because they can probably get a bacterium to synthesize the drug on a large scale in reactors. All they have to do is clone the DNA sequence responsible for the drug (it is simply a relatively short polypeptide) and overexpress it. Pretty easy to do, actually.

Unfortunately, this drug will never be available in pill form because it's a peptide, and those get degraded in the gut. So, Grandma is going to have to inject it.

Red Space Dragon

Couldn't have said it better myself. Thanks.
 
2005-04-04 04:30:22 AM  
Actually, Prialt is injected intrathecally by a metered pump. Direct into the space around the spinal cord. Doesn't work otherwise. And it has to be a metered pump or it'll kill you. They also don't mention that one of the possible side effects is psychosis. It's a big black-box warning at the top of the drug literature. Essentially, the only people who are going to be on Prialt are people who've already failed a morphine pump.
 
2005-04-04 09:35:14 AM  
sfphinkter: They won't actually have to use the snails because they can probably get a bacterium to synthesize the drug on a large scale in reactors. All they have to do is clone the DNA sequence responsible for the drug (it is simply a relatively short polypeptide) and overexpress it. Pretty easy to do, actually.

Trust me, I wasn't imagining snail farms. My point was, they needed the snails to study in the first place. Every time we eliminate a species, we eliminate the ability to study it (aside from bones and preserved carcasses).
 
2005-04-05 01:47:36 AM  
red_beard_neo I was watching a PBS special yesterday about venoms and they went into this same subject. For the most part they don't need to kill the snails. They harvest the poison from live ones.

Of course they can kill them, and do that to some, to get the poison and some are studied to find out other things, like how they make the poisons (though the show didn't go into that).
 
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